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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAP1L1 Gene

protein-coding   GIFtS: 56
GCID: GC12M076438

Nucleosome Assembly Protein 1-Like 1

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleosome Assembly Protein 1-Like 11 2     NAP1L2 5
NRP2 3     NAP12
hNRP2 3     HSP22-Like Protein Interacting Protein2
NAP-1-Related Protein2 3     NAP-1 Related Protein2

External Ids:    HGNC: 76371   Entrez Gene: 46732   Ensembl: ENSG000001871097   OMIM: 1640605   UniProtKB: P552093   

Export aliases for NAP1L1 gene to outside databases

Previous GC identifers: GC12M073514 GC12P075989 GC12M076156 GC12M074726


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NAP1L1 Gene:
This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA
replication and may play a role in modulating chromatin formation and contribute to the regulation of cell
proliferation. Alternative splicing of this gene results in several transcript variants; however, not all have
been fully described. (provided by RefSeq, Jul 2008)

GeneCards Summary for NAP1L1 Gene: 
NAP1L1 (nucleosome assembly protein 1-like 1) is a protein-coding gene. Diseases associated with NAP1L1 include emery-dreifuss muscular dystrophy, and muscular dystrophy. GO annotations related to this gene include protein binding. An important paralog of this gene is NAP1L3.

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209
Function: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation

Gene Wiki entry for NAP1L1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NAP1L1 gene promoter:
         E2F-4   E2F-3a   E2F-5   p300   E2F-2   AP-4   YY1   GATA-1   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAP1L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NAP1L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAP1L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21.2   Ensembl cytogenetic band:  12q21.2   HGNC cytogenetic band: 12q21.1

NAP1L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAP1L1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M076438:  view genomic region     (about GC identifiers)

Start:
76,438,670 bp from pter      End:
76,478,813 bp from pter
Size:
40,144 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209 (See protein sequence)
Recommended Name: Nucleosome assembly protein 1-like 1 precursor  
Size: 391 amino acids; 45374 Da
Subcellular location: Nucleus. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage
I to stage IV

Explore the universe of human proteins at neXtProt for NAP1L1: NX_P55209

Explore proteomics data for NAP1L1 at MOPED 

Post-translational modifications:

  • UniProtKB: Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in
    polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated
    due to the absence of functional TTLL10 in human (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P55209

  • NAP1L1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NAP1L1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_004528.1  NP_631946.1  

    ENSEMBL proteins: 
     ENSP00000261182   ENSP00000450236   ENSP00000376947   ENSP00000409795   ENSP00000446804  
     ENSP00000448167   ENSP00000437507   ENSP00000444759   ENSP00000445008   ENSP00000447793  
     ENSP00000448007   ENSP00000447196   ENSP00000446520   ENSP00000449649   ENSP00000448133  
     ENSP00000448764   ENSP00000446787   ENSP00000448836   ENSP00000446756   ENSP00000448661  
     ENSP00000449333  

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    ProSpec Recombinant Protein for NAP1L1
    Cloud-Clone Corp. Proteins for NAP1L1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0042470melanosome IEA--

    NAP1L1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR002164 NAP_family

    Graphical View of Domain Structure for InterPro Entry P55209

    ProtoNet protein and cluster: P55209

    1 Blocks protein domain: IPB002164 Nucleosome assembly protein (NAP)

    UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209
    Domain: The acidic domains are probably involved in the interaction with histones
    Similarity: Belongs to the nucleosome assembly protein (NAP) family


    NAP1L1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NP1L1_HUMAN, P55209
    Function: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11940655
         
    NAP1L1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NAP1L1:
     Decreased viability after Chla 

         1 MGI phenotypic allele for Nap1l1 (no phenotypes)

    NAP1L1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NAP1L1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAP1L1 
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    SwitchGear 3'UTR luciferase reporter plasmidNAP1L1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAP1L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/147 Interacting proteins for NAP1L1 (P552091, 2, 3 ENSP000002611824) via UniProtKB, MINT, STRING, and/or I2D (see all 147)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2BP678702, 3MINT-8253451 I2D: score=2 
    ENSG00000206406P678702, 3MINT-8253451 I2D: score=2 
    ENSG00000224398P678702, 3MINT-8253451 I2D: score=2 
    ENSG00000224774P678702, 3MINT-8253451 I2D: score=2 
    ENSG00000228875P678702, 3MINT-8253451 I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication TAS8297347
    GO:0006334nucleosome assembly IEA--
    GO:0008284positive regulation of cell proliferation TAS8297347

    NAP1L1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAP1L1 (NP1L1)

    Search CenterWatch for drugs/clinical trials and news about NAP1L1 / NP1L1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NAP1L1 gene (2 alternative transcripts): 
    NM_004537.4  NM_139207.2  

    Unigene Clusters for NAP1L1:

    Nucleosome assembly protein 1-like 1
    Hs.524599  [show with all ESTs], Hs.695185  [show with all ESTs]
    Unigene Representative Sequences: NM_004537, BM971179
    18/26 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
    ENST00000261182(uc001sxw.2 uc001sxx.2 uc010sty.1 uc001sxz.2 uc010stz.1 uc010sua.1 uc001syb.3)
    ENST00000552056 ENST00000393263 ENST00000431879 ENST00000552147 ENST00000547773
    ENST00000552013 ENST00000544816 ENST00000542344 ENST00000535020 ENST00000549596
    ENST00000547993 ENST00000547969 ENST00000552342 ENST00000547529 ENST00000548044
    ENST00000550934 ENST00000551992
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/97 QIAGEN miScript miRNA Assays for microRNAs that regulate NAP1L1 (see all 97):
    hsa-miR-124* hsa-miR-548j hsa-miR-3146 hsa-miR-199a-3p hsa-miR-218-1* hsa-miR-200a hsa-miR-30d hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidNAP1L1 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: AF088017.1 

    24/98 DOTS entries (see all 98):

    DT.95370575  DT.86998877  DT.97868590  DT.100698900  DT.92325026  DT.121178617  DT.99953720  DT.75168697 
    DT.100698902  DT.95370610  DT.100698923  DT.100698892  DT.100698889  DT.100698906  DT.100045864  DT.40292868 
    DT.95370818  DT.100698899  DT.91748847  DT.121178656  DT.121178652  DT.91781259  DT.121178681  DT.91781090 

    24/1688 AceView cDNA sequences (see all 1688):

    CB250488 NM_004537 BU608400 AA255453 AW673795 BQ683819 BF966048 BU737913 
    AA487388 BM680519 R78560 CR609205 AU077046 BE301027 AI061240 CD676893 
    BM695114 CB140373 AA620579 AW204421 AA256335 BE018780 CR593037 BQ059019 

    GeneLoc Exon Structure

    5/22 Alternative Splicing Database (ASD) splice patterns (SP) for NAP1L1 (see all 22)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c · 11d · 11e ^ 12 ^ 13a ·
    SP1:                                                        -                       -     -     -     -                                                         
    SP2:                          -                             -                       -     -     -     -                                                         
    SP3:                          -                             -                       -     -     -     -                                                         
    SP4:                          -                             -                             -     -     -                                                         
    SP5:                          -                             -                 -     -     -     -                                                               

    ExUns: 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b · 18c ^ 19
    SP1:                                                                  
    SP2:                                                                  
    SP3:                                                                  
    SP4:                                                                  
    SP5:                                                                  


    ECgene alternative splicing isoforms for NAP1L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAP1L1 expression in normal human tissues (normalized intensities)      NAP1L1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCTGACATA
    NAP1L1 Expression
    About this image


    NAP1L1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 20 entries
             Mononuclear Myocytes Cervical Primary Hypaxial Myotome
     
     Somite (Muscoskeletal System)    fully expand to see all 16 entries
             Mononuclear Myocytes Cervical Primary Hypaxial Myotome
     
     Limb (Muscoskeletal System)    fully expand to see all 4 entries
             Mononuclear Myocytes Hindlimb Dorsal Muscle
     
     Primitive Streak (Early Embryonic Tissues)
             Notochord
     
     Cartilage (Muscoskeletal System)
             Intervertebral Disc Nucleus Pulposus Cells Lumbar Intervertebral Disc

    See NAP1L1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAP1L1

    SOURCE GeneReport for Unigene clusters: Hs.524599 Hs.695185

    UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209
    Tissue specificity: Ubiquitously expressed

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NAP1L1 gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nap1l11 , 5 nucleosome assembly protein 1-like 11, 5 93.27(n)1
    98.21(a)1
      10 (58.67 cM)5
    536051  NM_001146707.11  NP_001140179.11 
     1114731925 
    chicken
    (Gallus gallus)
    Aves NAP1L11 nucleosome assembly protein 1-like 1 86.96(n)
    92.84(a)
      417864  XM_416106.3  XP_416106.1 
    lizard
    (Anolis carolinensis)
    Reptilia NAP1L16
    nucleosome assembly protein 1-like 1
    85(a)
    1 ↔ 1
    5(40559945-40619366)
    African clawed frog
    (Xenopus laevis)
    Amphibia nap1l1-prov2 nucleosome assembly protein 1-like 1 84.5(n)    BC043903.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nap1l12 nucleosome assembly protein 1, like 1 77.01(n)   368260  BC044152.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nap11 , 3 nucleosome assembly histone-specific
    chaperone3
    Nucleosome assembly protein 11
    47(a)
    (best of 2)3
    51.78(n)1
    49.16(a)1
      60A93
    377981  NM_057780.31  NP_477128.11 
    worm
    (Caenorhabditis elegans)
    Secernentea D2096.83
    nap-11
    Protein NAP-11 41(a)3
    50.97(n)1
    45.13(a)1
      IV(8378271-8379497)3
    1776361  NM_069021.51  NP_501422.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NAP16
    Protein that interacts with mitotic cyclin Clb2p; ...
    29(a)
    1 → many
    XI(525387-526640)
    rice
    (Oryza sativa)
    Liliopsida Os05g05397001 hypothetical protein 54.42(n)
    45.37(a)
      4339460  NM_001062710.1  NP_001056175.1 


    ENSEMBL Gene Tree for NAP1L1 (if available)
    TreeFam Gene Tree for NAP1L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NAP1L1 gene
    NAP1L32  NAP1L62  NAP1L22  NAP1L42  
    5 SIMAP similar genes for NAP1L1 using alignment to 20 protein entries:     NP1L1_HUMAN (see all proteins):
    NAP1L6    NAP1L4    NAP1L4b    NAP1L2    NAP1L3

    NAP1L1 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for NAP1L1
    PGOHUM00000261126 PGOHUM00000239403 PGOHUM00000258722 PGOHUM00000238149 PGOHUM00000261822


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/827 SNPs in NAP1L1 are shown (see all 827)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1819773251,2
    --76438218(+) TCCCAC/TAGGAA 2 -- ds50010--------
    rs753154961,2
    C,F--76438261(+) AGTAAT/CCTATT 2 -- ds50012Minor allele frequency- C:0.04WA NA 238
    rs751084371,2
    F--76438263(+) TAATCT/CATTAT 2 -- ds50011Minor allele frequency- C:0.09WA 118
    rs1436915641,2
    --76438301(+) TCAGAA/CTCTTG 2 -- ds50010--------
    rs1862071731,2
    --76438774(+) ACCATC/TACCAT 2 -- ut310--------
    rs788291071,2
    C,F--76438891(+) ATATAT/CGTACA 2 -- ut311Minor allele frequency- C:0.02EA 120
    rs1916585201,2
    --76438895(+) ATGTAC/TAGTGC 2 -- ut310--------
    rs1835486311,2
    --76438900(+) CAGTGC/TAGATT 2 -- ut310--------
    rs1863480281,2
    --76438906(+) AGATTA/TAAAAA 2 -- ut310--------
    rs1912552441,2
    --76439040(+) AAGGCC/TTAAAT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for NAP1L1 (76438670 - 76478813 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NAP1L1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NAP1L1
    DNA2.0 Custom Variant and Variant Library Synthesis for NAP1L1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 164060    OMIM disorders: --

    5 diseases for NAP1L1:    About MalaCards
    emery-dreifuss muscular dystrophy    muscular dystrophy    malaria    ovarian cancer
    breast cancer

    1 disease from the University of Copenhagen DISEASES database for NAP1L1:
    Emery-Dreifuss muscular dystrophy

    NAP1L1 for disorders           About GeneDecksing


    Export disorders for NAP1L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAP1L1 gene, integrated from 9 sources (see all 103):
    (articles sorted by number of sources associating them with NAP1L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation. (PubMed id 8297347)1, 2, 3 Simon H.-U....Siminovitch K.A. (1994)
    2. The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription. (PubMed id 18226242)1, 2 Vardabasso C.... Giacca M. (2008)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)1, 2 Chi A....Hunt D.F. (2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    6. A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. (PubMed id 15308774)1, 2 Kho Y.... Zhao Y. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The nucleosome assembly activity of NAP1 is enhanced by Alien. (PubMed id 17339334)1, 9 Eckey M....Baniahmad A. (2007)
    9. Functional characterization of human nucleosome assem bly protein 1-like proteins as histone chaperones. (PubMed id 20002496)1, 9 Okuwaki M....Nagata K. (2010)
    10. Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators. (PubMed id 11073993)1, 9 Shikama N....La Thangue N.B. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4673 HGNC: 7637 AceView: NAP1L1 Ensembl:ENSG00000187109 euGenes: HUgn4673
    ECgene: NAP1L1 H-InvDB: NAP1L1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAP1L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NAP1L1 gene:
    Search GeneIP for patents involving NAP1L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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