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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NAP1L1 Gene

protein-coding GIFtS: 54
GCID: GC12M076438

nucleosome assembly protein 1-like 1

Explore 5 diseases affiliated with
NAP1L1 via

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Nucleosome Assembly Protein 1-Like 1¹ ²		NAP-1-Related Protein² ³
NRP¹ ² ³		MGC23410¹
NAP1L¹ ² ⁵		MGC8688¹
NAP1¹ ²		HSP22-Like Protein Interacting Protein²
HNRP¹		NAP-1 Related Protein²

External Ids:	HGNC: 7637¹	Entrez Gene: 4673²	Ensembl: ENSG00000187109⁷	OMIM: 164060⁵	UniProtKB: P55209³

Export aliases for NAP1L1 gene to outside databases

Previous GC identifers: GC12M073514 GC12P075989 GC12M076156 GC12M074726

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NAP1L1:

This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA

replication and may play a role in modulating chromatin formation and contribute to the regulation of cell

proliferation. Alternative splicing of this gene results in several transcript variants; however, not all have been

fully described. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Function: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation

Gene Wiki entry for NAP1L1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NAP1L1 gene promoter:
E2F-4 E2F-3a E2F-5 p300 E2F-2 AP-4 YY1 GATA-1 E2F E2F-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NAP1L1 promoter sequence

Search SABiosciences Chromatin IP Primers for NAP1L1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAP1L1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21.2 Ensembl cytogenetic band: 12q21.2 HGNC cytogenetic band: 12q21.1

NAP1L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAP1L1 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M076438: view genomic region (about GC identifiers)

Start:	76,438,670 bp from pter	End:	76,478,813 bp from pter
Size:	40,144 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209 (See protein sequence)

Recommended Name: Nucleosome assembly protein 1-like 1 precursor

Size: 391 amino acids; 45374 Da

Subcellular location: Nucleus. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to

stage IV

Explore the universe of human proteins at neXtProt for NAP1L1: NX_P55209

Post-translational modifications:

Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate

chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence

of functional TTLL10 in human (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P55209

NAP1L1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_004528.1 NP_631946.1

ENSEMBL proteins:

ENSP00000261182 ENSP00000450236 ENSP00000376947 ENSP00000446305 ENSP00000409795

ENSP00000446804 ENSP00000448167 ENSP00000437507 ENSP00000444759 ENSP00000445008

ENSP00000447793 ENSP00000448007 ENSP00000447196 ENSP00000446520 ENSP00000449649

ENSP00000448133 ENSP00000448764 ENSP00000446787 ENSP00000448836 ENSP00000446756

ENSP00000448661 ENSP00000449333

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	Uscn Proteins for NAP1L1

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005678	chromatin assembly complex	--	--
GO:0042470	melanosome	IEA	--

NAP1L1 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NAP1L1 for domains About GeneDecksing

1 InterPro domain/family:

IPR002164 NAP_family

Graphical View of Domain Structure for InterPro Entry P55209

ProtoNet protein and cluster: P55209

1 Blocks protein family: IPB002164 Nucleosome assembly protein (NAP)

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Domain: The acidic domains are probably involved in the interaction with histones

Similarity: Belongs to the nucleosome assembly protein (NAP) family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Function: May be involved in modulating chromatin formation and contribute to regulation of cell proliferation

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NAP1L1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAP1L1
		8/97 QIAGEN miScript miRNA Assays for microRNAs that regulate NAP1L1 (see all 97):
		hsa-miR-124* hsa-miR-548j hsa-miR-3146 hsa-miR-199a-3p hsa-miR-218-1* hsa-miR-200a hsa-miR-30d hsa-miR-138-2*

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--

NAP1L1 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for NAP1L1:

Decreased viability after Chla

Animal Models:
1 MGI phenotypic allele

for Nap1l1 (no phenotypes)

NAP1L1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NAP1L1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/141 Interacting proteins for NAP1L1 (P55209^{1, 2, 3} ENSP00000261182⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 141)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TTLL10	Q6ZVT0²^,³, ENSP00000368591⁴	MINT-6493231 MINT-6493246 MINT-6493222 MINT-6493255 MINT-6493277 I2D: score=1 STRING: ENSP00000368591
TP53	P04637²^,³, ENSP00000269305⁴	MINT-72857 MINT-72858 I2D: score=1 STRING: ENSP00000269305
FSD1	Q9BTV5²^,³, ENSP00000221856⁴	MINT-63875 I2D: score=4 STRING: ENSP00000221856
CREBBP	Q92793¹^,³, ENSP00000262367⁴	EBI-356392,EBI-81215 I2D: score=3 STRING: ENSP00000262367
HBA1	P69905²^,³	MINT-63873 I2D: score=3

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006260	DNA replication	TAS	8297347
GO:0006334	nucleosome assembly	IEA	--
GO:0008284	positive regulation of cell proliferation	TAS	8297347

NAP1L1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NAP1L1
Search CenterWatch for drugs/clinical trials and news about NAP1L1 / NP1L1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NAP1L1 gene (2 alternative transcripts):

NM_004537.4 NM_139207.2

Unigene Clusters for NAP1L1:

Nucleosome assembly protein 1-like 1

Hs.524599 [show with all ESTs], Hs.695185 [show with all ESTs]

Unigene Representative Sequences: NM_004537, BM971179

18/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):

ENST00000261182(uc001sxw.2 uc001sxx.2 uc010sty.1 uc001sxz.2 uc010stz.1 uc010sua.1 uc001syb.3)

ENST00000552056 ENST00000393263 ENST00000540878 ENST00000431879 ENST00000552147

ENST00000547773 ENST00000552013 ENST00000544816 ENST00000542344 ENST00000535020

ENST00000549596 ENST00000547993 ENST00000547969 ENST00000552342 ENST00000547529

ENST00000548044 ENST00000550934

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAP1L1
		8/97 QIAGEN miScript miRNA Assays for microRNAs that regulate NAP1L1 (see all 97):
		hsa-miR-124* hsa-miR-548j hsa-miR-3146 hsa-miR-199a-3p hsa-miR-218-1* hsa-miR-200a hsa-miR-30d hsa-miR-138-2*

		SwitchGear 3'UTR luciferase reporter plasmid: NAP1L1 3' UTR sequence

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Additional cDNA sequence: AF088017.1

24/100 DOTS entries (see all 100):

DT.95370575 DT.86998877 DT.100698900 DT.97868590 DT.92325026 DT.121178617 DT.99953720 DT.75168697

DT.100698902 DT.95370610 DT.100698923 DT.100698892 DT.100698889 DT.100698906 DT.100045864 DT.40292868

DT.95370818 DT.100698899 DT.91748847 DT.121178656 DT.121178652 DT.91781259 DT.121178681 DT.91781090

24/1688 AceView cDNA sequences (see all 1688):

AI017431 AA262816 BM797430 BX384991 BQ637361 AF300335 BF196495 BQ773296

CB250488 AW088874 BE295809 CB107845 AA127585 BE018839 BF477462 BI850446

C00199 BQ949857 AI434138 AA864246 AI918869 BM667114 BM756611 BQ774647

GeneLoc Exon Structure

5/22 Alternative Splicing Database (ASD) splice patterns (SP) for NAP1L1 (see all 22) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3a	·	3b	·	3c	^	4	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8	^	9	^	10a	·	10b	^	11a	·	11b	·	11c	·	11d	·	11e	^	12	^	13a	·
SP1:																			-								-		-		-		-
SP2:									-										-								-		-		-		-
SP3:									-										-								-		-		-		-
SP4:									-										-										-		-		-
SP5:									-										-						-		-		-		-

ExUns:	13b	^	14	^	15	^	16a	·	16b	^	17a	·	17b	^	18a	·	18b	·	18c	^	19
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for NAP1L1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NAP1L1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCTGACATA

About this image

NAP1L1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10/22 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 22)

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Forelimb Dorsal Muscles

Mononuclear Myocytes

Skeletal Muscle

Limb

Forelimb Ventral Muscles

Mononuclear Myocytes

Skeletal Muscle

Limb

Hindlimb Dorsal Muscle

Mononuclear Myocytes

Skeletal Muscle

Limb

Hindlimb Ventral Muscle

Mononuclear Myocytes

Skeletal Muscle

Thoracic Epaxial Myotome

Mononuclear Myocytes

Skeletal Muscle

Somite

Cervical Epaxial Myotome

Mononuclear Myocytes

Skeletal Muscle

Somite

Cervical Hypaxial Myotome

Mononuclear Myocytes

Skeletal Muscle

Somite

Cervical Primary Epaxial Myotome

Mononuclear Myocytes

Skeletal Muscle

Somite

Cervical Primary Hypaxial Myotome

Mononuclear Myocytes

Skeletal Muscle

Somite

Lumbar Epaxial Myotome

Mononuclear Myocytes

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NAP1L1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NAP1L1

SOURCE GeneReport for Unigene clusters: Hs.524599 Hs.695185

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Tissue specificity: Ubiquitously expressed

SABiosciences Custom PCR Arrays for NAP1L1

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NAP1L1 gene from 8/32 species (see all 32) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	NAP1L1¹	nucleosome assembly protein 1-like 1	86.96(n) 92.84(a)		417864 XM_416106.3 XP_416106.1
lizard (Anolis carolinensis)	Reptilia	NAP1L1⁶	--	89(a)	1 ↔ 1	5(40559951-40576825)
African clawed frog (Xenopus laevis)	Amphibia	nap1l1-prov²	nucleosome assembly protein 1-like 1	84.5(n)		BC043903.1
zebrafish (Danio rerio)	Actinopterygii	nap1l1²	nucleosome assembly protein 1, like 1	77.01(n)		368260 BC044152.1
fruit fly (Drosophila melanogaster)	Insecta	Nap1^{1 , 3}	nucleosome assembly histone-specific chaperone³ Nucleosome assembly protein 1¹	47(a) (best of 2)³ 51.78(n)¹ 49.16(a)¹		60A9³ 37798¹ NM_057780.3¹ NP_477128.1¹
worm (Caenorhabditis elegans)	Secernentea	D2096.8³ nap-1¹	Protein NAP-1¹	41(a)³ 50.97(n)¹ 45.13(a)¹		IV(8378271-8379497)³ 177636¹ NM_069021.5¹ NP_501422.1¹
thale cress (Arabidopsis thaliana)	eudicotyledons	NAP1;1⁶ NAP1;3⁶ (see all 4)	nucleosome assembly protein 1-like 1 (see all 4)	36(a) 35(a) (see all 4)	many ↔ many many ↔ many (see all 4)	4(13232595-13235879) 5(23032449-23035661)
rice (Oryza sativa)	Liliopsida	Os05g0539700¹	hypothetical protein	54.42(n) 45.37(a)		4339460 NM_001062710.1 NP_001056175.1

ENSEMBL Gene Tree for NAP1L1 (if available)
TreeFam Gene Tree for NAP1L1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NAP1L1 gene

NAP1L3² NAP1L6² NAP1L2² NAP1L4² NAP1L5²

5 SIMAP similar genes for NAP1L1 using alignment to 21 protein entries: NP1L1_HUMAN (see all proteins):

NAP1L6 NAP1L4b NAP1L4 NAP1L2 NAP1L3

NAP1L1 for paralogs About GeneDecksing

5 Pseudogenes.org Pseudogenes for NAP1L1
PGOHUM00000261126 PGOHUM00000239403 PGOHUM00000258722 PGOHUM00000238149 PGOHUM00000261822

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181977325^1,2		--	76438218(+)	`TCCCAC/TAGGAA`	2	--	ds500¹		0	--	--	--	--
rs75315496^1,2	F,	--	76438261(+)	`AGTAAT/CCTATT`	2	--	ds500¹		2		WA NA	238
rs75108437^1,2	F,	--	76438263(+)	`TAATCT/CATTAT`	2	--	ds500¹		1		WA	118
rs143691564^1,2		--	76438301(+)	`TCAGAA/CTCTTG`	2	--	ds500¹		0	--	--	--	--
rs186207173^1,2		--	76438774(+)	`ACCATC/TACCAT`	2	--	ut3¹		0	--	--	--	--
rs78829107^1,2	F,	--	76438891(+)	`ATATAT/CGTACA`	2	--	ut3¹		1		EA	120
rs191658520^1,2		--	76438895(+)	`ATGTAC/TAGTGC`	2	--	ut3¹		0	--	--	--	--
rs183548631^1,2		--	76438900(+)	`CAGTGC/TAGATT`	2	--	ut3¹		0	--	--	--	--
rs186348028^1,2		--	76438906(+)	`AGATTA/TAAAAA`	2	--	ut3¹		0	--	--	--	--
rs191255244^1,2		--	76439040(+)	`AAGGCC/TTAAAT`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NAP1L1 (76438670 - 76478813 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NAP1L1: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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NAP1L1 for disorders           About GeneDecksing

OMIM gene information: 164060    OMIM disorders: --

5 diseases for NAP1L1:    About MalaCards

emery-dreifuss muscular dystrophy treacher collins syndrome muscular dystrophy breast cancer

malaria

Export disorders for NAP1L1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for NAP1L1 gene, integrated from 9 sources (see all 92):
(articles sorted by number of sources associating them with NAP1L1)

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Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation. (PubMed id 8297347)^{1, 2, 3} Simon H.-U....Siminovitch K.A. (1994)
The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription. (PubMed id 18226242)^{1, 2} Vardabasso C.... Giacca M. (2008)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{1, 2} Beausoleil S.A.... Gygi S.P. (2006)
Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)^{1, 2} Chi A....Hunt D.F. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. (PubMed id 15308774)^{1, 2} Kho Y.... Zhao Y. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The nucleosome assembly activity of NAP1 is enhanced by Alien. (PubMed id 17339334)^{1, 9} Eckey M....Baniahmad A. (2007)
Functional characterization of human nucleosome assem bly protein 1-like proteins as histone chaperones. (PubMed id 20002496)^{1, 9} Okuwaki M....Nagata K. (2010)
Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators. (PubMed id 11073993)^{1, 9} Shikama N....La Thangue N.B. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 4673	HGNC: 7637	AceView: NAP1L1	Ensembl:ENSG00000187109	euGenes: HUgn4673
ECgene: NAP1L1	H-InvDB: NAP1L1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NAP1L1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NAP1L1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for NAP1L1 gene:
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nucleosome assembly protein 1-like 1

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NAP1L1 Gene

nucleosome assembly protein 1-like 1

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