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NAP1L1 Gene

protein-coding GIFtS: 60

GC12M074726

nucleosome assembly protein 1-like 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
FLJ16112 ^²
MGC23410 ^¹, ²
MGC8688 ^¹, ²
NAP1 ^¹, ²
NAP1L ^¹, ², ⁵
NRP ^¹, ², ³
hNRP ^³

Descriptions
HSP22-like protein interacting protein ^²
NAP-1 related protein ^²
NAP-1-related protein ^³
nucleosome assembly protein 1-like 1 ^²

External Ids
HGNC: 7637¹
Entrez Gene: 4673²
UniProtKB: P55209³
Ensembl: ENSG00000187109⁷

Search outside databases for aliases for NAP1L1 gene

Previous GC identifers: GC12M073514 GC12P075989 GC12M076156

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for NAP1L1:

This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein

participates in DNA replication and may play a role in modulating chromatin formation and

contribute to the regulation of cell proliferation. Alternative splicing of this gene results in

several transcript variants; however, not all have been fully described. [provided by RefSeq]

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Function: May be involved in modulating chromatin formation and contribute to regulation of cell

proliferation

Gene Wiki entry for NAP1L1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NAP1L1 gene

Entrez Gene cytogenetic band: 12q21.2 Ensembl cytogenetic band: 12q21.2 HGNC cytogenetic band: 12q21.1

NAP1L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M074726: (about GC identifiers)

Start:	74,726,221 bp from pter
End:	74,764,717 bp from pter
Size:	38,497 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.10 NT_029419.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209 (See protein sequence)

Recommended Name: Nucleosome assembly protein 1-like 1

Size: 391 amino acids; 45374 Da

Subcellular location: Nucleus. Melanosome. Note=Identified by mass spectrometry in melanosome

fractions from stage I to stage IV

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_004528.1 NP_631946.1

ENSEMBL proteins:

ENSP00000261182 ENSP00000376947

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich AQUA Peptides for NAP1L1
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (NAP1L1)
	Human Recombinant Proteins from Abnova (NAP1L1)

OriGene Purified Recombinant Human Protein: NAP1L1

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005678	chromatin assembly complex	TAS	8297347
GO:0042470	melanosome	IEA	--

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Antibodies for NAP1L1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for NAP1L1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (NAP1L1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (NAP1L1)
	Novus Biologicals Antibodies for NAP1L1

Assays for NAP1L1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P55209

ProtoNet protein and cluster: P55209

1 Blocks protein family: IPB002164 Nucleosome assembly protein (NAP)

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Domain: The acidic domains are probably involved in the interaction with histones

Similarity: Belongs to the nucleosome assembly protein (NAP) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAP1L1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAP1L1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_004537

Applied Biosystems Silencer® siRNAs for NAP1L1

Sigma-Aldrich siRNA for NAP1L1

Sigma-Aldrich shRNA for NAP1L1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for NAP1L1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_004537
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_004537
untagged cDNA clones in CMV expression vector (see all 2): NM_004537

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_139207

UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209

Function: May be involved in modulating chromatin formation and contribute to regulation of cell

proliferation

1 MGI phenotypic allele for Nap1l1 (no phenotypes)

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	11940655

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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5/27 Interacting proteins for NAP1L1 (ENSP00000261182³ P55209^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 27 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CREBBP	Q92793¹	EBI-356392, EBI-81215
EP300	Q09472¹	EBI-356392, EBI-447295
TTLL10	Q6ZVT0²	MINT-6493231 MINT-6493246 MINT-6493222 MINT-6493255 MINT-6493277
TP53	P04637²	MINT-72857 MINT-72858
FSD1	Q9BTV5²	MINT-63875

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006260	DNA replication	TAS	8297347
GO:0006334	nucleosome assembly	TAS	8297347
GO:0008284	positive regulation of cell proliferation	TAS	8297347

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NAP1L1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAP1L1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAP1L1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_004537

Sigma-Aldrich siRNA for NAP1L1

Sigma-Aldrich shRNA for NAP1L1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004537 NM_139207

REFSEQ mRNAs for NAP1L1 gene (2 alternative transcripts):

NM_004537.4 NM_139207.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004537 NM_139207

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_004537
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_004537
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_004537

Additional cDNA sequence: AF088017.1

24/98 DOTS entries (see all 98 ):

DT.95370575 DT.86998877 DT.97868590 DT.100698900 DT.92325026 DT.121178617 DT.99953720 DT.75168697

DT.100698902 DT.95370610 DT.100698923 DT.100698892 DT.100698889 DT.100698906 DT.100045864 DT.40292868

DT.100698899 DT.95370818 DT.121178652 DT.121178656 DT.91748847 DT.91781259 DT.87009450 DT.121178681

24/1688 AceView cDNA sequences (see all 1688 ):

BQ009602 AA044935 BU608400 BM479891 AA805361 AA599720 BE675342 BQ884238

BF431151 CB215872 AA665466 BQ948185 BG110193 BX491540 CR620230 BQ637361

AI693385 BQ773669 BM680519 AA127585 BC018565 AA730326 BE328545 BM848615

highest scoring ESTs for NAP1L1:

M86667 AA053850 AA057684 AA071214 AA082229 AA083188 AA173360 AA223614 AA300484 AA311655

Unigene Clusters for NAP1L1:

Nucleosome assembly protein 1-like 1

Hs.524599 [show with all ESTs], Hs.695185 [show with all ESTs]

Unigene Representative Sequences: NM_004537, BG621980

GeneLoc Exon Structure

5/22 Alternative Splicing Database (ASD) splice patterns (SP) for NAP1L1 (see all 22 )

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3a	·	3b	·	3c	^	4	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8	^	9	^	10a	·	10b	^	11a	·	11b	·	11c	·	11d	·	11e	^	12	^	13a	·
SP1:																			-								-		-		-		-
SP2:									-										-								-		-		-		-
SP3:									-										-								-		-		-		-
SP4:									-										-										-		-		-
SP5:									-										-						-		-		-		-

ExUns:	13b	^	14	^	15	^	16a	·	16b	^	17a	·	17b	^	18a	·	18b	·	18c	^	19
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for NAP1L1

2 Ensembl transcripts including schematic representations:

ENST00000261182 ENST00000393263

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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NAP1L1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NAP1L1

¹ / ² / ³

23 probe-sets matching NAP1L1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
47018_at²^{, 3}	U95-B	1	1.00	1.00	0.66	0.82	AI168404	0.40	1.00	0.76	1
91187_s_at²^{, 3}	U95-E	1	1.00	1.00	0.85	1.02	AW003426	0.80	1.00	0.91	1
40634_at²^{, 3}	U95-A	1	1.00	1.00	0.95	0.85	M86667	1.00	1.00	1.00	1
91546_r_at²^{, 3}	U95-E	1	1.00	1.00	0.88	0.95	AA521396	0.80	1.00	0.91	1
72989_at²^{, 3}	U95-E	1	1.00	1.00	0.96	1.46	AI983719	0.80	1.00	0.91	1
34099_f_at²^{, 3}	U95-A	3	1.00	0.94	0.80	0.70	W26056	0.40	0.50	0.45	1
571_at²^{, 3}	U95-A	3	1.00	0.90	0.87	1.20	M86667	1.00	1.00	1.00	1
91189_r_at²^{, 3}	U95-E	1	0.94	1.00	0.94	0.90	AW003426	0.80	1.00	0.91	1
75321_f_at²^{, 3}	U95-D	4	0.81	0.56	0.87	1.11	AI985751	0.60	1.00	0.82	1
73229_at²^{, 3}	U95-E	1	0.62	1.00	0.94	1.00	AA053850	0.80	1.00	0.91	1
208754_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL162068	0.80	1.00	0.91	1
208753_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BC002387	0.80	1.00	0.91	1
204528_s_at²^{, 3}	U133-A	3	1.00	0.91	--	--	NM_004537	0.60	1.00	0.82	1
213864_s_at²^{, 3}	U133-A	3	1.00	0.76	--	--	AI985751	0.60	1.00	0.82	1
208752_x_at²^{, 3}	U133-A	4	1.00	0.61	--	--	AI888672	0.40	1.00	0.76	1
212967_x_at²^{, 3}	U133-A	3	0.73	0.65	--	--	AW148801	0.60	1.00	0.82	1
208754_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
208753_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1556121_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
204528_s_at²	U133Plus2	3	1.00	0.91	--	--	--	--	--	--	--
213864_s_at²	U133Plus2	3	1.00	0.76	--	--	--	--	--	--	--
208752_x_at²	U133Plus2	4	1.00	0.61	--	--	--	--	--	--	--
212967_x_at²	U133Plus2	3	0.73	0.65	--	--	--	--	--	--	--

GeneDecks NAP1L1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene clusters: Hs.524599 Hs.695185
Expression variation in blood from EXPOLDB for NAP1L1
UniProtKB/Swiss-Prot: NP1L1_HUMAN, P55209
Tissue specificity: Ubiquitously expressed

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NAP1L1 gene from 5/22 species (see all 22 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NAP1L1¹	--	nucleosome assembly protein 1-like 1	96.5(n) 99.49(a)	475407 XM_859567.1 XP_864660.1
chimpanzee (Pan troglodytes)	NAP1L1¹	--	nucleosome assembly protein 1-like 1	99.91(n) 100(a)	452083 XM_509226.2 XP_509226.2
cow (Bos taurus)	LOC540136¹	--	similar to Nucleosome assembly protein 1-like 1 (NAP-1-related more	96.25(n) 99.23(a)	540136 XM_872313.2 XP_877406.1
rat (Rattus norvegicus)	Nap1l1¹	--	nucleosome assembly protein 1-like 1	94.54(n) 98.21(a)	89825 NM_053561.2 NP_446013.2
mouse (Mus musculus)	Nap1l1^{1, 5}	10 (60.00 cM)⁵	nucleosome assembly protein 1-like 1^{1, 5}	93.35(n)¹ 98.21(a)¹	53605¹ NM_015781.3¹ NP_056596.1¹ AA407126⁵ AI256722⁵ (see all 39)

About this table Species with no ortholog for NAP1L1

ENSEMBL Gene Tree for NAP1L1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for NAP1L1 gene

NAP1L6² NAP1L3² NAP1L2² NAP1L5² NAP1L4²

Pseudogenes

4 related pseudogenes

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/243 NCBI SNPs in NAP1L1 are shown (see all 243 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 69)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1063104^1,2	A,C,F,H	74725926(-)	`GCCCAC/TGCACA`	2	--	ng5¹		4		EU EA WA	412
	rs7978288^1,2	A,C,F,H	74726001(+)	`ATAACT/CCAGAA`	2	--	ng5¹		11		EU EA WA NA	982
	rs7978060^1,2	C,F,H	74766557(+)	`TTGTGA/GTGGTT`	2	--	ng3¹ tfbs³		4		EU EA WA	418
	rs17116166^1,2	C,F,H	74725745(+)	`ATATAT/CGTGGC`	2	--	ng5¹		7		NA EU EA WA	562
	rs11180824^1,2	A,F	74764943(+)	`CGCGCC/TTGGGC`	2	--	ng3¹		2		MN EA	1252
--	rs11541040^1,2	F,H	74728087(+)	`CAAGCA/GGACTT`	2	--	int¹ ut3¹ ese³		3		EU EA	300
	rs12427136^1,2	C,H	74766447(+)	`TGCACG/TATGCA`	2	--	ng3¹		4		EU EA WA	408
--	rs1059187^1,2	F	74727423(-)	`AAAAAT/AAAAAT`	2	--	ut3¹ trp³		1		MN	184
--	rs1897645^1,2	A	74726459(-)	`AGCAAA/CATCAT`	2	--	ut3¹		0	--	--	--	--
--	rs11180814^1,2	C	74728411(+)	`TGTAAC/GTAAAT`	2	--	int¹ ut3¹ ese³		0	--	--	--	--

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HapMap Linkage Disequilibrium images for NAP1L1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 164060

1 PharmGKB disease relationship for NAP1L1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

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(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/49 PubMed articles for NAP1L1 gene (see all 49 ):

Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation. (PubMed id 8297347)^{2, 3, 4} Simon H.-U....Siminovitch K.A. (1994)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)^{3, 4} Chi A....Hunt D.F. (2006)
Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220)^{3, 4} Nousiainen M.... Koerner R. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. (PubMed id 15308774)^{3, 4} Kho Y.... Zhao Y. (2004)
The nucleosome assembly activity of NAP1 is enhanced by Alien. (PubMed id 17339334)^{1, 3} Eckey M....Baniahmad A. (2007)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS Spectra. (PubMed id 17924679)⁴ Yu L.-R.... Veenstra T.D. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 4673	HGNC: 7637	AceView: NAP1L1	Ensembl:ENSG00000187109	euGenes: HUgn4673
ECgene: NAP1L1	H-InvDB: NAP1L1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for NAP1L1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for NAP1L1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NAP1L1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NAP1L1		Antibodies for NAP1L1
	Explore super-pooled esiRNAs		Proteins for NAP1L1
	Lentivirus-delivered shRNAs for NAP1L1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
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Antibodies for NAP1L1

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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NAP1L1 Gene at Home site.
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NAP1L1 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for NAP1L1

Summaries
for NAP1L1

Genomic Location
for NAP1L1

Proteins
for NAP1L1

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Families
for NAP1L1

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Expression
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Orthologs
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NAP1L1 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor NAP1L1

Summariesfor NAP1L1

Genomic Locationfor NAP1L1

Proteinsfor NAP1L1

Protein Domains/Familiesfor NAP1L1

Gene Functionfor NAP1L1

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Transcriptsfor NAP1L1

Expression for NAP1L1

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Search for NAP1L1

Genome Databases showing NAP1L1

Other Databases showing NAP1L1

Specialized Databases showing NAP1L1

Licensable Technologiesfor NAP1L1

Servicesfor NAP1L1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NAP1L1

Summaries
for NAP1L1

Genomic Location
for NAP1L1

Proteins
for NAP1L1

Protein Domains/
Families
for NAP1L1

Gene Function
for NAP1L1

Pathways & Interactions
for NAP1L1

Drugs & Compounds
for NAP1L1

Transcripts
for NAP1L1

Expression
for NAP1L1

Orthologs
for NAP1L1

Paralogs
for NAP1L1

SNPs/Variants
for NAP1L1

Disorders & Mutations
for NAP1L1

Medical News
for NAP1L1

Publications
for NAP1L1

Licensable Technologies
for NAP1L1

Services
for NAP1L1