External Ids for NANOS3 Gene
Previous GeneCards Identifiers for NANOS3 Gene
GeneCards Summary for NANOS3 Gene
NANOS3 (Nanos Homolog 3 (Drosophila)) is a Protein Coding gene. Diseases associated with NANOS3 include spermatocytoma and premature ovarian failure. Among its related pathways are Platelet activation, signaling and aggregation and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include RNA binding. An important paralog of this gene is NANOS2.
UniProtKB/Swiss-Prot for NANOS3 Gene
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.