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Aliases for NAMPTP1 Gene

Aliases for NAMPTP1 Gene

  • Nicotinamide Phosphoribosyltransferase Pseudogene 1 2 3 5
  • Nicotinamide Phosphoribosyltransferase-Like 2 3
  • Pre-B-Cell Colony Enhancing Factor 2 2 3
  • Novel Protein Similar To Pre-B Cell Enhancing Factor (PBEF) 3
  • BA92J19.4 3
  • NAMPTL 3
  • PBEF2 3

External Ids for NAMPTP1 Gene

Previous HGNC Symbols for NAMPTP1 Gene

  • PBEF2
  • NAMPTL

Summaries for NAMPTP1 Gene

GeneCards Summary for NAMPTP1 Gene

NAMPTP1 (Nicotinamide Phosphoribosyltransferase Pseudogene 1) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAMPTP1 Gene

Genomics for NAMPTP1 Gene

Regulatory Elements for NAMPTP1 Gene

Enhancers for NAMPTP1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around NAMPTP1 on UCSC Golden Path with GeneCards custom track

Promoters for NAMPTP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around NAMPTP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for NAMPTP1 Gene

Chromosome:
10
Start:
36,521,721 bp from pter
End:
36,524,236 bp from pter
Size:
2,516 bases
Orientation:
Minus strand

Genomic View for NAMPTP1 Gene

Genes around NAMPTP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NAMPTP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NAMPTP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAMPTP1 Gene

Proteins for NAMPTP1 Gene

Post-translational modifications for NAMPTP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NAMPTP1 Gene

Domains & Families for NAMPTP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NAMPTP1 Gene

Function for NAMPTP1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NAMPTP1 Gene

Localization for NAMPTP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NAMPTP1 Gene

Pathways & Interactions for NAMPTP1 Gene

SuperPathways for NAMPTP1 Gene

No Data Available

Interacting Proteins for NAMPTP1 Gene

Gene Ontology (GO) - Biological Process for NAMPTP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NAMPTP1 Gene

Drugs & Compounds for NAMPTP1 Gene

(2) Drugs for NAMPTP1 Gene - From: ApexBio

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
FK866 (APO866) Pharma NAMPT inhibitor,non-competitive, highly specific 0
GNE-617 Pharma NAMPT inhibitor 0

(2) ApexBio Compounds for NAMPTP1 Gene

Compound Action Cas Number
FK866 (APO866) NAMPT inhibitor,non-competitive, highly specific 658084-64-1
GNE-617 NAMPT inhibitor 1362154-70-8
genes like me logo Genes that share compounds with NAMPTP1: view

Transcripts for NAMPTP1 Gene

mRNA/cDNA for NAMPTP1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NAMPTP1 Gene

No ASD Table

Relevant External Links for NAMPTP1 Gene

GeneLoc Exon Structure for
NAMPTP1
ECgene alternative splicing isoforms for
NAMPTP1

Expression for NAMPTP1 Gene

mRNA expression in normal human tissues for NAMPTP1 Gene

Protein differential expression in normal tissues from HIPED for NAMPTP1 Gene

This gene is overexpressed in Urine (29.8), Heart (24.1), and Saliva (10.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from for NAMPTP1 Gene



genes like me logo Genes that share expression patterns with NAMPTP1: view

Protein tissue co-expression partners for NAMPTP1 Gene

- Elite partner

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NAMPTP1 Gene

Orthologs for NAMPTP1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NAMPTP1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NAMPT 36
  • 92 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 91 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 80 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Nampt 36
  • 91 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 92 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia NAMPTL 36
  • 98 (a)
OneToOne
chicken
(Gallus gallus)
Aves PBEF1 36
  • 90 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 90 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii BX248331.2 36
  • 75 (a)
ManyToMany
CT033790.1 36
  • 75 (a)
ManyToMany
CT033790.3 36
  • 75 (a)
ManyToMany
nampta 36
  • 82 (a)
ManyToMany
si:dkey-145c18.2 36
  • 38 (a)
ManyToMany
si:dkey-145c18.3 36
  • 50 (a)
ManyToMany
Species with no ortholog for NAMPTP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NAMPTP1 Gene

ENSEMBL:
Gene Tree for NAMPTP1 (if available)
TreeFam:
Gene Tree for NAMPTP1 (if available)

Paralogs for NAMPTP1 Gene

Pseudogenes.org Pseudogenes for NAMPTP1 Gene

genes like me logo Genes that share paralogs with NAMPTP1: view

No data available for Paralogs for NAMPTP1 Gene

Variants for NAMPTP1 Gene

Variation tolerance for NAMPTP1 Gene

Gene Damage Index Score: 5.35; 70.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NAMPTP1 Gene

HapMap Linkage Disequilibrium report
NAMPTP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for NAMPTP1 Gene

Disorders for NAMPTP1 Gene

No disorders were found for NAMPTP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for NAMPTP1 Gene

Publications for NAMPTP1 Gene

  1. Cloning and characterization of the cDNA encoding a novel human pre- B-cell colony-enhancing factor. (PMID: 8289818) Samal B. … McNiece I. (Mol. Cell. Biol. 1994) 2 3 67
  2. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for NAMPTP1 Gene

Sources for NAMPTP1 Gene

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