Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAIF1 Gene

protein-coding   GIFtS: 44
GCID: GC09M130823

Nuclear Apoptosis Inducing Factor 1

(Previous name: chromosome 9 open reading frame 90)
(Previous symbol: C9orf90)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nuclear Apoptosis Inducing Factor 11 2
C9orf901 2 3 5
Nuclear Apoptosis-Inducing Factor 11 2
Chromosome 9 Open Reading Frame 901
RP11-379C10.22
bA379C10.22

External Ids:    HGNC: 254461   Entrez Gene: 2032452   Ensembl: ENSG000001711697   OMIM: 6106735   UniProtKB: Q69YI73   

Export aliases for NAIF1 gene to outside databases

Previous GC identifers: GC09M129864 GC09M100438


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NAIF1 Gene: 
NAIF1 (nuclear apoptosis inducing factor 1) is a protein-coding gene. Diseases associated with NAIF1 include esophagitis, and gastric cancer. GO annotations related to this gene include molecular_function.

UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7
Function: Induces apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008470.19  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NAIF1 gene promoter:
         Elk-1   NF-E2 p45   c-Ets-1   NRF-2   CBF-A   CBF-B   CP1A   NF-Y   NF-E2   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAIF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NAIF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAIF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.11   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.11

NAIF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAIF1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M130823:  view genomic region     (about GC identifiers)

Start:
130,823,512 bp from pter      End:
130,830,485 bp from pter
Size:
6,974 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7 (See protein sequence)
Recommended Name: Nuclear apoptosis-inducing factor 1  
Size: 327 amino acids; 35164 Da
Subunit: Interacts with HARBI1
Subcellular location: Nucleus
Secondary accessions: B3KV81 Q8WU12
Alternative splicing: 2 isoforms:  Q69YI7-1   Q69YI7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NAIF1: NX_Q69YI7

Explore proteomics data for NAIF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q69YI7

  • NAIF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NAIF1 Protein Expression
    REFSEQ proteins: NP_931045.1  
    ENSEMBL proteins: 
     ENSP00000362170  

    Human Recombinant Protein Products for NAIF1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for NAIF1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for NAIF1
    GenScript Custom Purified and Recombinant Proteins Services for NAIF1
    Novus Biologicals NAIF1 Protein
    Novus Biologicals NAIF1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NAIF1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA16378748

    NAIF1 for ontologies           About GeneDecksing



    NAIF1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NAIF1
    GenScript Custom Superior Antibodies Services for NAIF1
    Novus Biologicals NAIF1 Antibody
    Abcam antibodies for NAIF1
    Cloud-Clone Corp. Antibodies for NAIF1 
    Search ThermoFisher Antibodies for NAIF1
    Search LSBio for Antibodies for NAIF1 

    Assay Products for NAIF1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NAIF1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NAIF1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NAIF1 
    Cloud-Clone Corp. CLIAs for NAIF1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026753 NAIF1

    Graphical View of Domain Structure for InterPro Entry Q69YI7

    ProtoNet protein and cluster: Q69YI7

    UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7
    Similarity: Belongs to the NAIF1 family


    NAIF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAIF1_HUMAN, Q69YI7
    Function: Induces apoptosis

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    NAIF1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NAIF1:
     Elongated cells with protrusio  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NAIF1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NAIF1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAIF1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NAIF1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAIF1
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate NAIF1 (see all 20):
    hsa-miR-892b hsa-miR-125a-5p hsa-miR-4251 hsa-miR-146a hsa-miR-331-3p hsa-miR-128 hsa-miR-877* hsa-miR-10b*
    SwitchGear 3'UTR luciferase reporter plasmidNAIF1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NAIF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAIF1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NAIF1
    Sirion Biotech Customized adenovirus for overexpression of NAIF1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NAIF1 (see all 6)
    OriGene ORF clones in mouse, rat for NAIF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NAIF1 (NM_197956)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAIF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAIF1
    Sirion Biotech Customized lentivirus for stable overexpression of NAIF1 
                         Customized lentivirus expression plasmids for stable overexpression of NAIF1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NAIF1
    Search LifeMap BioReagents cell lines for NAIF1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAIF1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAIF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for NAIF1 (Q69YI73 ENSP000003621704) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    INTS5Q6P9B93, ENSP000003278894I2D: score=1 STRING: ENSP00000327889
    INTS3Q68E013, ENSP000003186414I2D: score=1 STRING: ENSP00000318641
    INTS6Q9UL033, ENSP000003102604I2D: score=1 STRING: ENSP00000310260
    ULK2Q8IYT83I2D: score=1 
    TERF2ENSP000002549424STRING: ENSP00000254942
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030308negative regulation of cell growth IDA16378748
    GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process IDA16378748

    NAIF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAIF1

    Search CenterWatch for drugs/clinical trials and news about NAIF1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NAIF1 gene: 
    NM_197956.3  

    Unigene Clusters for NAIF1:

    Nuclear apoptosis inducing factor 1
    Hs.373606  [show with all ESTs], Hs.740682  [show with all ESTs]
    Unigene Representative Sequences: NM_197956, BX359223
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000470245(uc022bnv.1) ENST00000373078(uc004bta.3) ENST00000488519
    ENST00000466139
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAIF1
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate NAIF1 (see all 20):
    hsa-miR-892b hsa-miR-125a-5p hsa-miR-4251 hsa-miR-146a hsa-miR-331-3p hsa-miR-128 hsa-miR-877* hsa-miR-10b*
    SwitchGear 3'UTR luciferase reporter plasmidNAIF1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NAIF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAIF1
    Clone
    Products:
         
    OriGene clones in human, mouse for NAIF1 (see all 6)
    OriGene ORF clones in mouse, rat for NAIF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NAIF1 (NM_197956)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAIF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAIF1
    Sirion Biotech Customized lentivirus for stable overexpression of NAIF1 
                         Customized lentivirus expression plasmids for stable overexpression of NAIF1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NAIF1
    OriGene qSTAR qPCR primer pairs in human, mouse for NAIF1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAIF1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAIF1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAIF1

    Additional mRNA sequence: BC047160.1 

    6 DOTS entries:

    DT.97764185  DT.112629  DT.91687588  DT.91990219  DT.91849110  DT.100748534 

    24/91 AceView cDNA sequences (see all 91):

    AA359485 BC013371 CR591717 CA310459 CA426093 CA312400 AI417373 AA642586 
    AI752966 AA340072 CA426906 CA427966 AW079405 AA885000 AA927393 AA411902 
    BM511394 BM757831 AI969211 BX103094 BM740522 AI864878 BF724764 BU162007 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NAIF1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6
    SP1:                    -     -                                             
    SP2:              -     -     -                                             
    SP3:                          -     -                                       
    SP4:                          -                                             
    SP5:                                                                        


    ECgene alternative splicing isoforms for NAIF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAIF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGACTCTT
    NAIF1 Expression
    About this image


    See NAIF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAIF1

    SOURCE GeneReport for Unigene clusters: Hs.373606 Hs.740682

    UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7
    Tissue specificity: Widely expressed

        SABiosciences Custom PCR Arrays for NAIF1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NAIF1
    OriGene qSTAR qPCR primer pairs in human, mouse for NAIF1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAIF1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAIF1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAIF1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAIF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NAIF1 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Naif11 , 5 nuclear apoptosis inducing factor 11, 5 88.07(n)1
    93.88(a)1
      2 (22.09 cM)5
    712541  NM_194335.21  NP_919316.11 
     324504575 
    chicken
    (Gallus gallus)
    Aves NAIF11 nuclear apoptosis inducing factor 1 73.71(n)
    75.39(a)
      417229  NM_001030692.1  NP_001025863.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia AL848131.22   -- 75.91(n)    AL848131.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5627551 nuclear apoptosis inducing factor 1 69.72(n)
    68.81(a)
      562755  NM_001126405.1  NP_001119877.1 


    ENSEMBL Gene Tree for NAIF1 (if available)
    TreeFam Gene Tree for NAIF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/136 SNPs in NAIF1 are shown (see all 136)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs108193421,2
    C,F,A--130823135(+) GACCTC/TGTGAT 1 -- int13Minor allele frequency- T:0.50NA 6
    rs1113469761,2
    C,F--130823164(+) CAAAGC/TGCTGG 1 -- int12Minor allele frequency- T:0.50WA CSA 4
    rs359158821,2
    C--130823344(+) AAAAA-/A/AA  
            
    GCCAC
    1 -- int11NA 2
    rs340662661,2
    C--130823345(+) AAAAA-/A/A   
       A
    /AAA
    AAAAA
    2 -- int1 cds11NA 2
    rs1174838021,2
    F--130823370(+) CCACAG/CGTTCA 1 -- int11Minor allele frequency- C:0.03NA 120
    rs1469126701,2
    --130823534(+) TATGTA/CTTTAA 1 -- ut310--------
    rs1814504551,2
    C--130823556(+) GACCCA/GGAAAT 1 -- ut310--------
    rs1856083861,2
    --130823633(+) CAGATA/TTCCAA 1 -- ut310--------
    rs1899727051,2
    --130823791(+) CCCTCA/GCTGGG 1 -- ut310--------
    rs412762201,2
    C,F--130823834(+) GCACTG/ACACGA 1 -- ut311Minor allele frequency- A:0.01NA 120

    HapMap Linkage Disequilibrium report for NAIF1 (130823512 - 130830485 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NAIF1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831727CNV Loss17160897
    nsv893859CNV Loss21882294
    nsv471324CNV Gain18288195

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NAIF1
    DNA2.0 Custom Variant and Variant Library Synthesis for NAIF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610673    OMIM disorders: --

    2 diseases for NAIF1:    About MalaCards
    esophagitis    gastric cancer


    NAIF1 for disorders           About GeneDecksing


    Export disorders for NAIF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAIF1 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with NAIF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Overexpression of the novel human gene, nuclear apoptosis-inducing factor 1, induces apoptosis. (PubMed id 16378748)1, 2, 3 Lv B.... Lou Y. (2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (2004)
    3. Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes. (PubMed id 18339812)1, 2 Sinzelle L....Ivics Z. (2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    6. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    7. NAIF1 is down-regulated in gastric cancer and promote s apoptosis through the caspase-9 pathway in human MKN45 cells. (PubMed id 21286669)1 Luo Q....Huang C. (2011)
    8. Streamlined analysis schema for high-throughput ident ification of endogenous protein complexes. (PubMed id 20133760)1 Malovannaya A....Qin J. (2010)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 203245 HGNC: 25446 AceView: C9orf90 Ensembl:ENSG00000171169 euGenes: HUgn203245
    ECgene: NAIF1 H-InvDB: NAIF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAIF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NAIF1 gene:
    Search GeneIP for patents involving NAIF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NAIF1  
     OriGene qPCR primer pairs and template standards for NAIF1   OriGene Protein Over-expression Lysate for NAIF1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NAIF1  
     OriGene qSTAR qPCR primer pairs in human, mouse for NAIF1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NAIF1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NAIF1   OriGene Custom Protein Services for NAIF1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NAIF1
     QIAGEN SeqTarget long-range PCR primers for resequencing NAIF1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAIF1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAIF1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAIF1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAIF1
     GenScript Custom Purified and Recombinant Proteins Services for NAIF1 GenScript cDNA clones with any tag delivered in your preferred vector for NAIF1
     GenScript Custom Assay Services for NAIF1 GenScript Custom Superior Antibodies Services for NAIF1
     GenScript Custom overexpressing Cell Line Services for NAIF1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NAIF1 promoter
     Search Chromatin IP Primers for NAIF1
     RT2 qPCR Primer Assay in human, mouse, rat NAIF1
     Search GNC Networks for NAIF1
     SABiosciences Custom PCR Arrays for NAIF1
     Search Tocris compounds for NAIF1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NAIF1 antibodies
     NAIF1 proteins
     NAIF1 lysates
     Antibodies for NAIF1
     See all of Abcam's Antibodies, Kits and Proteins for NAIF1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for NAIF1
     Antibodies for NAIF1
     ELISAs for NAIF1
     CLIAs for NAIF1
     Search LifeMap BioReagents cell lines for NAIF1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAIF1
     SwitchGear 3'UTR luciferase reporter plasmids for NAIF1
     SwitchGear Promoter luciferase reporter plasmids for NAIF1
     Search ThermoFisher Antibodies for NAIF1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAIF1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NAIF1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NAIF1
    Customized:
     lentivirus for stable overexpression of NAIF1
     lentivirus expression plasmids for stable overexpression of NAIF1
     adenovirus for overexpression of NAIF1
     Search LSBio for Antibodies for NAIF1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NAIF1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4