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NAIF1 Gene

protein-coding   GIFtS: 43
GCID: GC09M130823

Nuclear Apoptosis Inducing Factor 1

(Previous name: chromosome 9 open reading frame 90)
(Previous symbol: C9orf90)
  Search for NAIF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear Apoptosis Inducing Factor 11 2
C9orf901 2 3 5
Nuclear Apoptosis-Inducing Factor 11 2
Chromosome 9 Open Reading Frame 901
bA379C10.22

External Ids:    HGNC: 254461   Entrez Gene: 2032452   Ensembl: ENSG000001711697   OMIM: 6106735   UniProtKB: Q69YI73   

Export aliases for NAIF1 gene to outside databases

Previous GC identifers: GC09M129864 GC09M100438


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NAIF1 Gene:
NAIF1 (nuclear apoptosis inducing factor 1) is a protein-coding gene.

UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7
Function: Induces apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NAIF1 gene promoter:
         Elk-1   NF-E2 p45   c-Ets-1   NRF-2   CBF-A   CBF-B   CP1A   NF-Y   NF-E2   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAIF1 promoter sequence
   Search Chromatin IP Primers for NAIF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NAIF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.11   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.11

NAIF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAIF1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M130823:  view genomic region     (about GC identifiers)

Start:
130,823,512 bp from pter      End:
130,830,485 bp from pter
Size:
6,974 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7 (See protein sequence)
Recommended Name: Nuclear apoptosis-inducing factor 1  
Size: 327 amino acids; 35164 Da
Subunit: Interacts with HARBI1
Secondary accessions: B3KV81 Q8WU12
Alternative splicing: 2 isoforms:  Q69YI7-1   Q69YI7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NAIF1: NX_Q69YI7

Explore proteomics data for NAIF1 at MOPED


See NAIF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_931045.1  
ENSEMBL proteins: 
 ENSP00000362170  

NAIF1 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for NAIF1

 
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Abcam antibodies for NAIF1
Cloud-Clone Corp. Antibodies for NAIF1
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NAIF1 Assay Products:

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Cloud-Clone Corp. ELISAs for NAIF1
Cloud-Clone Corp. CLIAs for NAIF1
Search eBioscience for ELISAs for NAIF1 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR028002 Myb_DNA-bind_5
 IPR026753 NAIF1

Graphical View of Domain Structure for InterPro Entry Q69YI7

ProtoNet protein and cluster: Q69YI7

UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7
Similarity: Belongs to the NAIF1 family


Find genes that share domains with NAIF1           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: NAIF1_HUMAN, Q69YI7
Function: Induces apoptosis

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
Find genes that share ontologies with NAIF1           About GenesLikeMe


Phenotypes:
     2 GenomeRNAi human phenotypes for NAIF1:
 Elongated cells with protrusio  Increased gamma-H2AX phosphory 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NAIF1
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NAIF1

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAIF1
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NAIF1

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat NAIF1 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate NAIF1 (see all 20):
hsa-miR-892b hsa-miR-125a-5p hsa-miR-4251 hsa-miR-146a hsa-miR-331-3p hsa-miR-128 hsa-miR-877* hsa-miR-10b*
SwitchGear 3'UTR luciferase reporter plasmidNAIF1 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for NAIF1
Predesigned siRNA for gene silencing in human, mouse, rat NAIF1

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for NAIF1

Clone
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OriGene clones in human, mouse for NAIF1 (see all 6)
OriGene ORF clones in mouse, rat for NAIF1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NAIF1 (NM_197956)
Sino Biological Human cDNA Clone for NAIF1
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAIF1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAIF1

Cell Line
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GenScript Custom overexpressing Cell Line Services for NAIF1
Browse ESI BIO Cell Lines and PureStem Progenitors for NAIF1 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAIF1


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
NAIF1_HUMAN, Q69YI7: Nucleus
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
cytosol2
mitochondrion1

Gene Ontology (GO): 4 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005730NOT nucleolus IDA--
GO:0005739mitochondrion IDA16378748
GO:0005886plasma membrane IDA--

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NAIF1
Interactions:

    Search GeneGlobe Interaction Network for NAIF1

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

Selected Interacting proteins for NAIF1 (Q69YI73 ENSP000003621704) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
InteractantInteraction Details
GeneCardExternal ID(s)
INTS5Q6P9B93, ENSP000003278894I2D: score=1 STRING: ENSP00000327889
INTS3Q68E013, ENSP000003186414I2D: score=1 STRING: ENSP00000318641
INTS6Q9UL033, ENSP000003102604I2D: score=1 STRING: ENSP00000310260
ULK2Q8IYT83I2D: score=1 
TERF2ENSP000002549424STRING: ENSP00000254942
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0030308negative regulation of cell growth IDA16378748
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process IDA16378748

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for NAIF1



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for NAIF1 gene: 
NM_197956.3  

Unigene Cluster for NAIF1:

Nuclear apoptosis inducing factor 1
Hs.373606  [show with all ESTs]
Unigene Representative Sequence: NM_197956
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000470245(uc022bnv.1) ENST00000373078(uc004bta.3) ENST00000488519
ENST00000466139
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat NAIF1 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate NAIF1 (see all 20):
hsa-miR-892b hsa-miR-125a-5p hsa-miR-4251 hsa-miR-146a hsa-miR-331-3p hsa-miR-128 hsa-miR-877* hsa-miR-10b*
SwitchGear 3'UTR luciferase reporter plasmidNAIF1 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for NAIF1
Predesigned siRNA for gene silencing in human, mouse, rat NAIF1
Clone
Products:
     
OriGene clones in human, mouse for NAIF1 (see all 6)
OriGene ORF clones in mouse, rat for NAIF1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NAIF1 (NM_197956)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAIF1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAIF1
Primer
Products:
    
OriGene qPCR primer pairs and template standards for NAIF1
OriGene qSTAR qPCR primer pairs in human, mouse for NAIF1
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAIF1
  QuantiTect SYBR Green Assays in human, mouse, rat NAIF1
  QuantiFast Probe-based Assays in human, mouse, rat NAIF1

Additional mRNA sequence: 

AK122729.1 AL833392.1 BC013371.2 BC021580.1 

6 DOTS entries:

DT.97764185  DT.112629  DT.91687588  DT.91990219  DT.91849110  DT.100748534 

Selected AceView cDNA sequences (see all 91):

BX103094 AI417373 AA359485 BM511394 AI752966 AA411902 AA885000 CA427966 
CA312400 AI969211 AW079405 AA642586 BC013371 CA426906 BM740522 CR591717 
AA340072 BM757831 CA426093 AA927393 CA310459 AA631602 AW769468 CB241622 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for NAIF1 (see all 6)    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6
SP1:                    -     -                                             
SP2:              -     -     -                                             
SP3:                          -     -                                       
SP4:                          -                                             
SP5:                                                                        


ECgene alternative splicing isoforms for NAIF1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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NAIF1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CTGGACTCTT
NAIF1 Expression
About this image

NAIF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

NAIF1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.373606

UniProtKB/Swiss-Prot: NAIF1_HUMAN, Q69YI7
Tissue specificity: Widely expressed

    Custom PCR Arrays for NAIF1
Primer
Products:
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OriGene qSTAR qPCR primer pairs in human, mouse for NAIF1
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAIF1
QuantiTect SYBR Green Assays in human, mouse, rat NAIF1
QuantiFast Probe-based Assays in human, mouse, rat NAIF1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAIF1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for NAIF1 gene from Selected species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Naif11 , 5 nuclear apoptosis inducing factor 11, 5 88.07(n)1
93.88(a)1
  2 (22.09 cM)5
712541  NM_194335.21  NP_919316.11 
 324504575 
chicken
(Gallus gallus)
Aves NAIF11 nuclear apoptosis inducing factor 1 72.56(n)
74.45(a)
  417229  NM_001030692.1  NP_001025863.1 
tropical clawed frog
(Xenopus tropicalis)
Amphibia AL848131.22   -- 75.91(n)    AL848131.2 
zebrafish
(Danio rerio)
Actinopterygii naif11 nuclear apoptosis inducing factor 1 69.97(n)
68.6(a)
  562755  NM_001126405.1  NP_001119877.1 


ENSEMBL Gene Tree for NAIF1 (if available)
TreeFam Gene Tree for NAIF1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for NAIF1 (see all 136)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 9 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs108193421,2
C,F,A--130823135(+) GACCTC/TGTGAT 1 -- int13Minor allele frequency- T:0.50NA 6
rs1113469761,2
C,F--130823164(+) CAAAGC/TGCTGG 1 -- int12Minor allele frequency- T:0.50WA CSA 4
rs359158821,2
C--130823344(+) AAAAA-/A/AA  
        
GCCAC
1 -- int11NA 2
rs340662661,2
C--130823345(+) AAAAA-/A/A   
   A
/AAA
AAAAA
2 -- int1 cds11NA 2
rs1174838021,2
F--130823370(+) CCACAG/CGTTCA 1 -- int11Minor allele frequency- C:0.03NA 120
rs1469126701,2
--130823534(+) TATGTA/CTTTAA 1 -- ut310--------
rs1814504551,2
C--130823556(+) GACCCA/GGAAAT 1 -- ut310--------
rs1856083861,2
--130823633(+) CAGATA/TTCCAA 1 -- ut310--------
rs1899727051,2
--130823791(+) CCCTCA/GCTGGG 1 -- ut310--------
rs412762201,2
C,F--130823834(+) GCACTG/ACACGA 1 -- ut311Minor allele frequency- A:0.01NA 120

HapMap Linkage Disequilibrium report for NAIF1 (130823512 - 130830485 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for NAIF1:    About this table    
Variant IDTypeSubtypePubMed ID
nsv831727CNV Loss17160897
nsv893859CNV Loss21882294
nsv471324CNV Gain18288195

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing NAIF1
DNA2.0 Custom Variant and Variant Library Synthesis for NAIF1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 610673    OMIM disorders: --


Find genes that share disorders with NAIF1           About GenesLikeMe


Export disorders for NAIF1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for NAIF1 gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with NAIF1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Overexpression of the novel human gene, nuclear apoptosis-inducing factor 1, induces apoptosis. (PubMed id 16378748)1, 2, 3 Lv B.... Lou Y. (Int. J. Biochem. Cell Biol. 2006)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes. (PubMed id 18339812)1, 2 Sinzelle L.... Ivics Z. (Proc. Natl. Acad. Sci. U.S.A. 2008)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
  6. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (amp 2011)
  7. NAIF1 is down-regulated in gastric cancer and promotes apoptosis through the caspase-9 pathway in human MKN45 cells. (PubMed id 21286669)1 Luo Q....Huang C. (Oncol. Rep. 2011)
  8. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. (PubMed id 20133760)1 Malovannaya A....Qin J. (Proc. Natl. Acad. Sci. U.S.A. 2010)
  9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
  10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 203245 HGNC: 25446 AceView: C9orf90 Ensembl:ENSG00000171169 euGenes: HUgn203245
ECgene: NAIF1 H-InvDB: NAIF1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for NAIF1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for NAIF1 gene:
Search GeneIP for patents involving NAIF1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for NAIF1   OriGene RNAi products in human, mouse, rat for NAIF1  
 OriGene qPCR primer pairs and template standards for NAIF1   OriGene Protein Over-expression Lysate for NAIF1  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for NAIF1  
 OriGene qSTAR qPCR primer pairs in human, mouse for NAIF1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for NAIF1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for NAIF1   OriGene Custom Protein Services for NAIF1  

 
 
 Block miRNA regulation of human, mouse, rat NAIF1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NAIF1
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NAIF1 Predesigned siRNA for gene silencing in human, mouse, rat NAIF1
 QuantiFast Probe-based Assays in human, mouse, rat NAIF1 QuantiTect SYBR Green Assays in human, mouse, rat NAIF1
 Custom PCR Arrays for NAIF1 Search Chromatin IP Primers for NAIF1
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAIF1  Search GeneGlobe Interaction Network for NAIF1
 Regulatory tfbs in NAIF1 promoter
 GenScript Custom Purified and Recombinant Proteins Services for NAIF1 GenScript cDNA clones with any tag delivered in your preferred vector for NAIF1
 GenScript Custom Assay Services for NAIF1 GenScript Custom overexpressing Cell Line Services for NAIF1
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for NAIF1
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 cDNA Clones for NAIF1
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 NAIF1 antibodies
 NAIF1 proteins
 NAIF1 lysates
 Antibodies for NAIF1
 See all of Abcam's Antibodies, Kits and Proteins for NAIF1
 Custom Antibody / Protein Production Service
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 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for NAIF1
 Antibodies for NAIF1
 ELISAs for NAIF1
 CLIAs for NAIF1



 Browse ESI BIO Cell Lines and PureStem Progenitors for NAIF1
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAIF1
 SwitchGear 3'UTR luciferase reporter plasmids for NAIF1
 SwitchGear Promoter luciferase reporter plasmids for NAIF1
 Search ThermoFisher Antibodies for NAIF1
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAIF1
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NAIF1
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NAIF1
 Search LSBio for Antibodies for NAIF1
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for NAIF1
  Search eBioscience for proteins for NAIF1
  Search eBioscience for elisas for NAIF1
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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