V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

NAGS Gene

protein-coding GIFtS: 60

GC17P039437

N-acetylglutamate synthase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AGAS ^¹, ²
ARGA ^¹, ²
EC 2.3.1.1 ^³
MGC133025 ^²
NAT7 ^¹

Descriptions
Amino-acid acetyltransferase ^³
N-acetylglutamate synthase ^²

External Ids
HGNC: 17996¹
Entrez Gene: 162417²
UniProtKB: Q8N159³
Ensembl: ENSG00000161653⁷

Search outside databases for aliases for NAGS gene

Previous GC identifers: GC17P041823 GC17P044259 GC17P042092 GC17P042557

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for NAGS:

The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of

N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl

phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may

regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in

N-acetylglutamate synthase have been associated with hyperammonemia. [provided by RefSeq]

UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159

Function: Plays a role in the regulation of ureagenesis by producing variable amounts of

N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NAGS gene

Entrez Gene cytogenetic band: 17q21.31 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31

NAGS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P039437: (about GC identifiers)

Start:	39,437,558 bp from pter
End:	39,441,962 bp from pter
Size:	4,405 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000017.9 NT_010783.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159 (See protein sequence)

Recommended Name: N-acetylglutamate synthase, mitochondrial precursor

Size: 534 amino acids; 58156 Da

Subcellular location: Mitochondrion matrix

Secondary accessions: B2RAZ9 Q8IWR4

Post-translational modifications:

Probably processed by mitochondrial processing peptidase (MPP). The long form has not yet been

isolated (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_694551.1

ENSEMBL proteins:

ENSP00000293404

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (NAGS)
	Human Recombinant Proteins from Abnova (NAGS)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--
GO:0005759	mitochondrial matrix	IEA	--

About this table

Antibodies for NAGS:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for NAGS
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (NAGS), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (NAGS)
	Novus Biologicals Antibody for NAGS

Assays for NAGS:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8N159

ProtoNet protein and cluster: Q8N159

UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159

Similarity: Belongs to the acetyltransferase family

Similarity: Contains 1 N-acetyltransferase domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAGS)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAGS)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_153006

Applied Biosystems Silencer® siRNAs for NAGS

Sigma-Aldrich siRNA for NAGS

Sigma-Aldrich shRNA for NAGS

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_153006
Myc/DDK tagged cDNA clone in CMV expression vector: NM_153006
untagged cDNA clone in CMV expression vector: NM_153006

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_153006

UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159

Function: Plays a role in the regulation of ureagenesis by producing variable amounts of

N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity

Catalytic activity: Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate

Enzyme regulation: Increased by L-arginine

Enzyme Number (IUBMB): EC 2.3.1.1

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003991	acetylglutamate kinase activity	IEA	--
GO:0004042	amino-acid N-acetyltransferase activity	IEA	--
GO:0008415	acyltransferase activity	IEA	--
GO:0016740	transferase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for NAGS (Your Favorite Gene powered by Ingenuity)

Urea Cycle and Metabolism of Amino Groups

GeneDecks NAGS for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159

Pathway: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from

L-glutamate: step 1/4

5/22 Interacting proteins for NAGS (ENSP00000293404³ Q8N159²) via UniProtKB, MINT, and/or STRING (see all 22 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TMEM39B	Q9GZU3²	MINT-64900
CPS1	ENSP00000233072³	STRING (score=.963)
ALDH18A1	ENSP00000360268³	STRING (score=.917)
ADC	ENSP00000362540³	STRING (score=.875)
GLS2	ENSP00000310447³	STRING (score=.874)

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000050	urea cycle	IEA	--
GO:0006526	arginine biosynthetic process	IEA	--
GO:0006536	glutamate metabolic process	IEA	--
GO:0008152	metabolic process	IEA	--
GO:0008652	amino acid biosynthetic process	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NAGS
7 Novoseek chemical compound relationships for NAGS gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
n-acetylglutamate	98.59	105	2241918 (4), 11131349 (3), 12459178 (2), 14605506 (2) (see all 31)
n-carbamylglutamate	97.49	14	18414145 (3), 17421020 (2), 15480384 (2), 17510757 (1)
cpsi	89.67	9	12459178 (2), 15050968 (2), 12633501 (1), 16321554 (1)
carbamoyl phosphate	88.88	10	12459178 (1), 15050968 (1), 12594532 (1), 15164414 (1) (see all 7)
urea	68.13	16	18666241 (2), 12459178 (1), 12754705 (1), 12633501 (1) (see all 10)
acetyl-coa	57.90	4	16321554 (1), 12447942 (1)
ornithine	56.26	3	12633501 (1), 15164414 (1), 2105747 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAGS)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAGS)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_153006

Sigma-Aldrich siRNA for NAGS

Sigma-Aldrich shRNA for NAGS

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_153006

REFSEQ mRNAs for NAGS gene:

NM_153006.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_153006

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_153006
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_153006
                                 untagged cDNA clone in CMV expression vector: NM_153006

Additional cDNA sequence:

AK074407.1 AK300923.1 AK314432.1 AY116538.1 AY158070.1 BC111713.1

3 DOTS entries:

DT.100021284 DT.40107565 DT.410925

24/34 AceView cDNA sequences (see all 34 ):

NM_153006 BF589712 AY116538 AI193178 BX106329 AX747266 AI076316 AI241153

W86007 CK724890 AY158070 AK074407 AA703140 AK091938 BI909116 BE222718

AI470965 AA385859 AA700249 AV696264 N46975 T48765 BF195825 N34056

highest scoring ESTs for NAGS:

AI076316 AA385859 AA700249 AA703140 AI193178 AI241153 AI470965 AI952208 AK074407 AV696264

Unigene Cluster for NAGS:

N-acetylglutamate synthase

Hs.8876 [show with all ESTs]

Unigene Representative Sequence: NM_153006

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for NAGS

ExUns:	1	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6a	·	6b	^	7a	·	7b
SP1:											-
SP2:											-				-
SP3:

About this scheme

ECgene alternative splicing isoforms for NAGS

1 Ensembl transcript including schematic representation:

ENST00000293404

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

NAGS expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NAGS

¹ / ² / ³

3 probe-sets matching NAGS gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
47145_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	AI076316	1.00	1.00	1.00	1
229432_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AV696264	0.80	1.00	0.91	1
229432_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks NAGS for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ACCCCAGGCA

SOURCE GeneReport for Unigene cluster: Hs.8876
UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159
Tissue specificity: Highly expressed in the adult liver, kidney and small intestine. Weakly
expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NAGS gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NAGS¹	--	N-acetylglutamate synthase	87.39(n) 88.39(a)	490943 XM_548066.2 XP_548066.2
chimpanzee (Pan troglodytes)	NAGS¹	--	N-acetylglutamate synthase	99.69(n) 99.81(a)	468274 XM_001152480.1 XP_001152480.1
cow (Bos taurus)	NAGS¹	--	N-acetylglutamate synthase	86.64(n) 87.08(a)	538004 XM_618194.3 XP_618194.2
rat (Rattus norvegicus)	Nags¹	--	N-acetylglutamate synthase	83.49(n) 86.91(a)	303563 XM_220939.3 XP_220939.1
mouse (Mus musculus)	Nags^{1, 5}	11⁵	N-acetylglutamate synthase^{1, 5}	83.24(n)¹ 86.72(a)¹	217214¹ NM_145829.1¹ NP_665828.1¹ AF462069⁵ AI415708⁵ (see all 10)

About this table Species with no ortholog for NAGS

ENSEMBL Gene Tree for NAGS

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/23 NCBI SNPs in NAGS are shown (see all 23 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 30)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs186636^1,2	A,C,F,H	39441498(-)	`GGTGAG/AGGTCA`	1	--	ut3¹ ese³		10		MN EA EU WA NA	2460
	rs640631^1,2	A,C,F,H	39441706(+)	`CAACTT/CGACTC`	1	--	ut3¹ ese³		9		MN EU EA WA	1018
--	rs189052^1,2	A,C	39442028(-)	`gtcttA/Taaaaa`	1	--	ng3¹		0	--	--	--	--
	rs1994366^1,2	A,C	39442337(+)	`GGGAGG/TAGAAG`	1	--	ng3¹		0	--	--	--	--
--	rs170639^1,2	A,C,F	39440878(-)	`TGGGGG/CTTAGG`	1	--	int¹		1		MN	184
	rs228770^1,2	A,C	39439366(-)	`CCCCTA/GCCCCC`	1	--	int¹		0	--	--	--	--
	rs228773^1,2	A,C	39440676(-)	`GTGGCA/GGGACC`	1	--	int¹		0	--	--	--	--
	rs228772^1,2	A,C	39439903(-)	`TCTCCC/TGGTCG`	1	--	int¹		0	--	--	--	--
	rs228771^1,2	F	39439623(-)	`TCCCCC/GGCCCG`	1	--	int¹		1		MN	184
--	rs9893971^1,2	--	39442094(+)	`cagccC/Ttgacc`	1	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for NAGS (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 608300 disorders: 237310

UniProtKB/Swiss-Prot: NAGS_HUMAN, Q8N159

Defects in NAGS are the cause of N-acetylglutamate synthase deficiency (NAGSD)

[MIM:237310]. NAGSD is a rare autosomal recessively inherited metabolic disorder leading to severe

neonatal or late onset hyperammonemia without increased excretion of orotic acid. Clinical

symptoms are somnolence, tachypnea, feeding difficulties, a severe neurologic presentation

characterized by uncontrollable movements, developmental delay, visual impairment, failure to

thrive and hyperammonemia precipitated by the introduction of high-protein diet or febrile illness

2 Novoseek disease relationships for NAGS gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
nags deficiency	99.29	53	17510757 (5), 17421020 (4), 12594532 (3), 18414145 (3) (see all 18)
hyperammonemia	90.59	18	12594532 (2), 18414145 (2), 11131349 (2), 12459178 (1) (see all 13)

About this table

Human Gene Mutation Database: NAGS
Genetic Association Database: NAGS

(Possibly Related Articles in Doctor's Guide)
About This Section

New Driving Criteria For People With Epilepsy

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/35 PubMed articles for NAGS gene (see all 35 ):

Cloning and expression of the human N-acetylglutamate synthase gene. (PubMed id 12459178)^{1, 2, 3, 4} Caldovic L....Tuchman M. (2002)
Mutation analysis in patients with N-acetylglutamate synthase deficiency. (PubMed id 12754705)^{1, 3, 4} Haeberle J.... Koch H.G. (2003)
Null mutations in the N-acetylglutamate synthase gene associated with acute neonatal disease and hyperammonemia. (PubMed id 12594532)^{1, 3, 6} Caldovic L....Tuchman M. (2003)
Mammalian N-acetylglutamate synthase. (PubMed id 15050968)^{1, 2, 3} Morizono H....Tuchman M. (2004)
Identification of novel mutations of the human N-acetylglutamate synthase gene and their functional investigation by expression studies. (PubMed id 15878741)^{1, 3, 4} Schmidt E.... Koch H.G. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Mutations and polymorphisms in the human N-acetylglutamate synthase (NAGS) gene. (PubMed id 17421020)^{1, 3} Caldovic L....Tuchman M. (2007)
Biochemical properties of recombinant human and mouse N-acetylglutamate synthase. (PubMed id 16321554)^{1, 3} Caldovic L....Tuchman M. (2006)
Deficiency of the carnitine transporter (OCTN2) with partial N-acetylglutamate synthase (NAGS) deficiency. (PubMed id 17703373)^{1, 3} Hwu W.L....Lee N.C. (2007)
Late onset N-acetylglutamate synthase deficiency caused by hypomorphic alleles. (PubMed id 15714518)^{1, 3} Caldovic L....Tuchman M. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 162417	HGNC: 17996	AceView: NAGS	Ensembl:ENSG00000161653	euGenes: HUgn162417
ECgene: NAGS	H-InvDB: NAGS

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
GeneReviews	http://www.genetests.org/query?gene=NAGS
Wikipedia	http://en.wikipedia.org/wiki/N-acetylglutamate_synthase

Licensable Technologies for NAGS
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for NAGS:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NAGS-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NAGS		Antibodies for NAGS
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for NAGS		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (NAGS)
	Antibodies (NAGS)
	Chimera RNAi (NAGS)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (NAGS)
	Antibodies (NAGS)

Search OriGene for NAGS

Search Tocris compounds for NAGS

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for NAGS

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
NAGS Gene at Home site.
Version 2.41.1
server5.xennexinc.com

NAGS Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for NAGS

Summaries
for NAGS

Genomic Location
for NAGS

Proteins
for NAGS

Protein Domains/
Families
for NAGS

Gene Function
for NAGS

Pathways & Interactions
for NAGS

Drugs & Compounds
for NAGS

Transcripts
for NAGS

Expression
for NAGS

Orthologs
for NAGS

Paralogs
for NAGS

SNPs/Variants
for NAGS

Disorders & Mutations
for NAGS

Medical News
for NAGS

Publications
for NAGS

Search for NAGS

Genome Databases showing NAGS

Other Databases showing NAGS

Specialized Databases showing NAGS

Licensable Technologies
for NAGS

Services
for NAGS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NAGS Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor NAGS

Summariesfor NAGS

Genomic Locationfor NAGS

Proteinsfor NAGS

Protein Domains/Familiesfor NAGS

Gene Functionfor NAGS

Pathways & Interactionsfor NAGS

Drugs & Compoundsfor NAGS

Transcriptsfor NAGS

Expression for NAGS

Orthologsfor NAGS

Paralogsfor NAGS

SNPs/Variantsfor NAGS

Disorders & Mutationsfor NAGS

Medical Newsfor NAGS

Publicationsfor NAGS

Search for NAGS

Genome Databases showing NAGS

Other Databases showing NAGS

Specialized Databases showing NAGS

Licensable Technologiesfor NAGS

Servicesfor NAGS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NAGS

Summaries
for NAGS

Genomic Location
for NAGS

Proteins
for NAGS

Protein Domains/
Families
for NAGS

Gene Function
for NAGS

Pathways & Interactions
for NAGS

Drugs & Compounds
for NAGS

Transcripts
for NAGS

Expression
for NAGS

Orthologs
for NAGS

Paralogs
for NAGS

SNPs/Variants
for NAGS

Disorders & Mutations
for NAGS

Medical News
for NAGS

Publications
for NAGS

Licensable Technologies
for NAGS

Services
for NAGS