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NAGPA Gene

protein-coding GIFtS: 50

GC16M005014

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
APAA ^¹, ²
EC 3.1.4.45 ^³
UCE ^¹, ²

Descriptions
Mannose 6-phosphate-uncovering enzyme ^², ³
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase ^²
Phosphodiester alpha-GlcNAcase ^², ³
alpha-N-acetylglucosaminyl phosphodiesterase ^²
lysosomal alpha-N-acetylglucosaminidase ^²

External Ids
HGNC: 17378¹
Entrez Gene: 51172²
UniProtKB: Q9UK23³
Ensembl: ENSG00000103174⁷

Search outside databases for aliases for NAGPA gene

Previous GC identifers: GC16M005107 GC16M005075

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for NAGPA:

Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the

trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation

of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as

'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues

from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction

most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two

disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the

protein's C-terminus contains multiple signals for trafficking it between lysosomes, the

plasma membrane, and trans-Golgi network. [provided by RefSeq]

UniProtKB/Swiss-Prot: NAGPA_HUMAN, Q9UK23

Function: Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on

lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose

moieties, which are formed in the first step

Gene Wiki entry for NAGPA

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NAGPA gene

Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3

NAGPA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M005014: (about GC identifiers)

Start:	5,014,846 bp from pter
End:	5,023,937 bp from pter
Size:	9,092 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000016.8 NT_037887.4

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: NAGPA_HUMAN, Q9UK23 (See protein sequence)

Recommended Name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor

Size: 515 amino acids; 56153 Da

Subunit: Homotetramer arranged as two disulfide-linked homodimers (By similarity)

Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein.

Note=Cis/medial Golgi

Secondary accessions: Q96EJ8

Alternative splicing: 3 isoforms: Q9UK23-1 Q9UK23-2 Q9UK23-3

REFSEQ proteins: NP_057340.2

ENSEMBL proteins:

ENSP00000310998 ENSP00000371381

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse Abcam for Recombinant Proteins
	Human Recombinant Proteins from Abnova (NAGPA)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005794	Golgi apparatus	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	TAS	10551838

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Antibodies for NAGPA:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Monoclonal and Polyclonal Antibodies from Abnova (NAGPA)
	Novus Biologicals Antibody for NAGPA

Assays for NAGPA:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UK23

ProtoNet protein and cluster: Q9UK23

UniProtKB/Swiss-Prot: NAGPA_HUMAN, Q9UK23

Domain: The tyrosine-based internalization signal may be essential for its retrieval from the

plasma membrane to the TGN

Domain: The C-terminal NPFKD sequence is an attractive candidate for either an endocytosis signal

acting at the plasma membrane or a retrieval signal acting at the TGN to return the enzyme to the

cis/medial-Golgi

Similarity: Contains 1 EGF-like domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAGPA)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAGPA)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016256

Applied Biosystems Silencer® siRNAs for NAGPA

Sigma-Aldrich siRNA for NAGPA

Sigma-Aldrich shRNA for NAGPA

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_016256
Myc/DDK tagged cDNA clone in CMV expression vector: NM_016256
untagged cDNA clone in CMV expression vector: NM_016256

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_016256

UniProtKB/Swiss-Prot: NAGPA_HUMAN, Q9UK23

Function: Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on

lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose

moieties, which are formed in the first step

Catalytic activity: Glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H(2)O =

N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose

Enzyme Number (IUBMB): EC 3.1.4.45

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	TAS	10551838
GO:0016787	hydrolase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: NAGPA_HUMAN, Q9UK23

Pathway: Protein modification; protein glycosylation

5/13 Interacting proteins for NAGPA (ENSP00000310998³) via UniProtKB, MINT, and/or STRING (see all 13 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ALPI	ENSP00000295463³	STRING (score=.868)
ALPL	ENSP00000363965³	STRING (score=.868)
CD4	ENSP00000011653³	STRING (score=.756)
ICAM1	ENSP00000264832³	STRING (score=.746)
CD8A	ENSP00000283635³	STRING (score=.744)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	10551838
GO:0006464	protein modification process	TAS	10551838
GO:0006622	protein targeting to lysosome	TAS	10551838
GO:0007040	lysosome organization	TAS	10551838

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NAGPA
5 Novoseek chemical compound relationships for NAGPA gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
mannose 6-phosphate	89.04	12	15864430 (1), 12058031 (1), 17927214 (1), 8294420 (1) (see all 7)
udp-n-acetylglucosamine	75.62	2	8294420 (1), 2167847 (1)
n-acetylglucosamine	72.69	6	15864430 (1), 12058031 (1), 7786023 (1), 11408573 (1)
phosphodiester	72.65	15	8294420 (4), 10551838 (4), 7786023 (2)
mannose	45.67	2	12058031 (1), 11723124 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAGPA)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAGPA)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016256

Sigma-Aldrich siRNA for NAGPA

Sigma-Aldrich shRNA for NAGPA

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_016256

REFSEQ mRNAs for NAGPA gene:

NM_016256.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_016256

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_016256
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_016256
                                 untagged cDNA clone in CMV expression vector: NM_016256

Additional cDNA sequence:

AF052111.1 AF187072.1 AK025570.1 AK026122.1 AK127952.1 AK302916.1 AK314320.1 BC012194.1

CR598113.1 CR599974.1 CR601621.1

11 DOTS entries:

DT.312162 DT.100790624 DT.100790628 DT.92023445 DT.95199040 DT.100790623 DT.95280284 DT.100024248

DT.100767383 DT.87010533 DT.92424627

24/131 AceView cDNA sequences (see all 131 ):

BU844409 CB123089 CR598113 CR601621 BI193076 AL524697 BM457386 CR599974

AA047671 AW239249 BU859544 BI753989 BU188674 BX352485 AI805575 AF052111

BX401157 BX341574 BI517588 AI452628 BQ372847 BX377209 BI518126 BQ962119

highest scoring ESTs for NAGPA:

AF187072 AK025570 AK026122 AK127952 AU280565 AW239249 BC012194 BG328417 BG422200 BG470128

Unigene Cluster for NAGPA:

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Hs.21334 [show with all ESTs]

Unigene Representative Sequence: BC012194

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for NAGPA (see all 13 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2	^	3	^	4	^	5	^	6a	·	6b	·	6c	^	7	^	8a	·	8b	^	9a	·	9b	·	9c	^	10	^	11a	·	11b	·	11c	·	11d	^	12	^	13a	·	13b	·
SP1:													-						-
SP2:													-						-								-		-
SP3:
SP4:													-						-								-		-		-		-		-		-		-		-		-		-		-
SP5:											-		-						-								-		-

ExUns:	13c
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for NAGPA

2 Ensembl transcripts including schematic representations:

ENST00000312251 ENST00000381955

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

NAGPA expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NAGPA

¹ / ² / ³

5 probe-sets matching NAGPA gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
48811_at²^{, 3}	U95-B	1	1.00	1.00	0.88	1.27	AW007594	0.60	1.00	0.82	1
38956_at²^{, 3}	U95-A	1	1.00	1.00	0.77	1.00	AF052111	0.60	1.00	0.82	1
70257_i_at²^{, 3}	U95-D	1	1.00	1.00	0.76	0.74	AI805575	0.40	1.00	0.76	1
205090_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_016256	0.60	1.00	0.82	1
205090_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTTACAGACC

SOURCE GeneReport for Unigene cluster: Hs.21334
Expression variation in blood from EXPOLDB for NAGPA

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NAGPA gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NAGPA¹	--	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	86.58(n) 85.8(a)	490019 XM_547139.2 XP_547139.2
chimpanzee (Pan troglodytes)	NAGPA¹	--	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	99.35(n) 99.61(a)	453894 XM_510795.2 XP_510795.2
cow (Bos taurus)	NAGPA¹	--	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	85.37(n) 83.11(a)	515935 XM_594044.3 XP_594044.2
rat (Rattus norvegicus)	Nagpa¹	--	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	81.81(n) 81.36(a)	360476 XM_340751.3 XP_340752.2
mouse (Mus musculus)	Nagpa^{1, 5}	16⁵	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase^{1, 5}	82.33(n)¹ 80.58(a)¹	27426¹ NM_013796.2¹ NP_038824.1¹ AF187073⁵ AI596180⁵ (see all 18)

About this table Species with no ortholog for NAGPA

ENSEMBL Gene Tree for NAGPA

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/68 NCBI SNPs in NAGPA are shown (see all 68 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 55)

AB	SNP ID	Valid	Chr 16 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs7110^1,2	A,C,F,H,O	5014953(-)	`GATGAA/GATCAT`	1	--	ut3¹		18		EA MN EU WA NA	3138
	rs1045693^1,2	A,C,F,H	5015227(-)	`GCTGCC/TGAGAA`	1	--	ut3¹ ese³		13		EU EA WA NA	2118
	rs7188856^1,2	A,C,F,H	5015634(+)	`CTGCAG/ATGCTG`	1	I/T	mis¹ ese³		11		EU EA WA NA	948
--	rs15951^1,2	A,C,F	5015249(-)	`TGCTTT/CTCGCC`	1	--	ut3¹		5		MN NA EA	546
	rs917897^1,2	C,F,H	5015154(-)	`TGCCAA/GCGAAC`	1	--	ut3¹ ese³		8		MN EU EA WA NA	736
	rs887855^1,2	F,H	5015341(-)	`GATAGC/GACTTG`	1	--	ut3¹		8		NA EA MN EU WA	838
--	rs2937113^1,2	C	5015247(-)	`CTTCTC/GGCCTG`	1	--	ut3¹ ese³		0	--	--	--	--
	rs13380613^1,2	H	5015428(+)	`AGCCAG/AACCGT`	1	--	ut3¹		4		EU EA WA	386
--	rs2908666^1,2	C	5025078(-)	`ctgggC/Tgacaa`	1	--	ng3¹		0	--	--	--	--
--	rs12448709^1,2	C	5014426(+)	`aaaaaA/Gtttta`	1	--	ng5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for NAGPA (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 607985

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/18 PubMed articles for NAGPA gene (see all 18 ):

Molecular cloning and functional expression of two splice forms of human N-acetylglucosamine-1-phosphodiester alpha-N- acetylglucosaminidase. (PubMed id 10551838)^{1, 2, 3, 4} Kornfeld R.H.... Canfield W.M. (1999)
Human mannose 6-phosphate-uncovering enzyme is synthesized as a proenzyme that is activated by the endoprotease furin. (PubMed id 12058031)^{1, 2, 3} Do H....Kornfeld S. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Lysosomal hydrolase mannose 6-phosphate uncovering enzyme resides in the trans-Golgi network. (PubMed id 11408573)^{1, 3} Rohrer J. and Kornfeld R. (2001)
Purification and characterization of human serum N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (PubMed id 7786023)^{1, 3} Lee J.K. and Pierce M. (1995)
Multiple signals regulate trafficking of the mannose 6-phosphate-uncovering enzyme. (PubMed id 11723124)^{1, 3} Lee W.S....Kornfeld S. (2002)
Purification and characterization of human lymphoblast N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (PubMed id 8922957)^{1, 3} Page T....Miller A.L. (1996)
Characterization of the TGN exit signal of the human mannose 6-phosphate uncovering enzyme. (PubMed id 15976452)³ Nair P....Rohrer J. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 51172	HGNC: 17378	AceView: NAGPA	Ensembl:ENSG00000103174	euGenes: HUgn51172
ECgene: NAGPA	H-InvDB: NAGPA

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for NAGPA
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for NAGPA:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NAGPA-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NAGPA		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for NAGPA		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Antibodies for NAGPA

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NAGPA Gene

protein-coding GIFtS: 50

Aliases &
Descriptions
for NAGPA

Summaries
for NAGPA

Genomic Location
for NAGPA

Proteins
for NAGPA

Protein Domains/
Families
for NAGPA

Gene Function
for NAGPA

Pathways & Interactions
for NAGPA

Drugs & Compounds
for NAGPA

Transcripts
for NAGPA

Expression
for NAGPA

Orthologs
for NAGPA

Paralogs
for NAGPA

SNPs/Variants
for NAGPA

Disorders & Mutations
for NAGPA

Medical News
for NAGPA

Publications
for NAGPA

Search for NAGPA

Genome Databases showing NAGPA

Other Databases showing NAGPA

Specialized Databases showing NAGPA

Licensable Technologies
for NAGPA

Services
for NAGPA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NAGPA Gene

protein-coding GIFtS: 50

Aliases & Descriptionsfor NAGPA

Summariesfor NAGPA

Genomic Locationfor NAGPA

Proteinsfor NAGPA

Protein Domains/Familiesfor NAGPA

Gene Functionfor NAGPA

Pathways & Interactionsfor NAGPA

Drugs & Compoundsfor NAGPA

Transcriptsfor NAGPA

Expression for NAGPA

Orthologsfor NAGPA

Paralogsfor NAGPA

SNPs/Variantsfor NAGPA

Disorders & Mutationsfor NAGPA

Medical Newsfor NAGPA

Publicationsfor NAGPA

Search for NAGPA

Genome Databases showing NAGPA

Other Databases showing NAGPA

Specialized Databases showing NAGPA

Licensable Technologiesfor NAGPA

Servicesfor NAGPA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NAGPA

Summaries
for NAGPA

Genomic Location
for NAGPA

Proteins
for NAGPA

Protein Domains/
Families
for NAGPA

Gene Function
for NAGPA

Pathways & Interactions
for NAGPA

Drugs & Compounds
for NAGPA

Transcripts
for NAGPA

Expression
for NAGPA

Orthologs
for NAGPA

Paralogs
for NAGPA

SNPs/Variants
for NAGPA

Disorders & Mutations
for NAGPA

Medical News
for NAGPA

Publications
for NAGPA

Licensable Technologies
for NAGPA

Services
for NAGPA