Aliases for NAGA Gene
External Ids for NAGA Gene
Previous GeneCards Identifiers for NAGA Gene
NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease). [provided by RefSeq, Jul 2008]
GeneCards Summary for NAGA Gene
NAGA (Alpha-N-Acetylgalactosaminidase) is a Protein Coding gene. Diseases associated with NAGA include Kanzaki Disease and Schindler Disease, Type I. Among its related pathways are Lysosome and Glycosphingolipid biosynthesis - globo series. GO annotations related to this gene include protein homodimerization activity and alpha-galactosidase activity. An important paralog of this gene is GLA.
UniProtKB/Swiss-Prot for NAGA Gene
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.