V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

NAGA Gene

protein-coding GIFtS: 62

GC22M040784

N-acetylgalactosaminidase, alpha-
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
D22S674 ^¹, ²
EC 3.2.1.49 ^³
GALB ^²
alpha-N-acetylgalactosaminidase ^²

Descriptions
Acetylgalactosaminidase, alpha-N- (alpha-galactosidase B) ^²
Alpha-galactosidase B ^³
N-acetylgalactosaminidase, alpha- ^²

External Ids
HGNC: 7631¹
Entrez Gene: 4668²
UniProtKB: P17050³
Ensembl: ENSG00000198951⁷

Search outside databases for aliases for NAGA gene

Previous GC identifers: GC22M039068 GC22M040697 GC22M040778

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for NAGA:

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves

alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified

as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).

[provided by RefSeq]

Gene Wiki entry for NAGA

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NAGA gene

Entrez Gene cytogenetic band: 22q13-qter|22q11 Ensembl cytogenetic band: 22q13.2 HGNC cytogenetic band: 22q13-qter

NAGA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22M040784: (about GC identifiers)

Start:	40,784,331 bp from pter
End:	40,796,792 bp from pter
Size:	12,462 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000022.9 NT_011520.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: NAGAB_HUMAN, P17050 (See protein sequence)

Recommended Name: Alpha-N-acetylgalactosaminidase precursor

Size: 411 amino acids; 46565 Da

Subcellular location: Lysosome

Miscellaneous: Alpha-galactosidase B was first found to be an isoenzyme of alpha-galactosidases,

but apparently it differs from alpha-galactosidase A in substrate specificity and is

alpha-N-acetylgalactosaminidase

Sequence caution: Sequence=AAA59902.1; Type=Frameshift; Positions=320;

REFSEQ proteins: NP_000253.1

ENSEMBL proteins:

ENSP00000384603 ENSP00000385283 ENSP00000355349 ENSP00000379680

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (NAGA)
	Human Recombinant Proteins from Abnova (NAGA)

OriGene Purified Recombinant Human Protein: NAGA

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005764	lysosome	IEA	--

About this table

Antibodies for NAGA:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for NAGA
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (NAGA), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (NAGA)
	Novus Biologicals Antibodies for NAGA

Assays for NAGA:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P17050

ProtoNet protein and cluster: P17050

1 Blocks protein family: IPB002241 Glycosyl hydrolase family 27 signature

UniProtKB/Swiss-Prot: NAGAB_HUMAN, P17050

Similarity: Belongs to the glycosyl hydrolase 27 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAGA)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000262

Applied Biosystems Silencer® siRNAs for NAGA

Sigma-Aldrich siRNA and siRNA Panels for NAGA

Sigma-Aldrich shRNA for NAGA

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for NAGA
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000262
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000262
untagged cDNA clone in CMV expression vector: NM_000262

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000262

UniProtKB/Swiss-Prot: NAGAB_HUMAN, P17050

Catalytic activity: Hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in

N-acetyl-alpha-D-galactosaminides

Enzyme Number (IUBMB): EC 3.2.1.49

Genatlas biochemistry entry for NAGA:

acetyl-galactosaminidase,alpha-N-,lyposomal,catalyzing the degradation of

alpha-N-acetylgalactosaminyl-containing glycoconjugates

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	--
GO:0008456	alpha-N-acetylgalactosaminidase activity	TAS	2174888
GO:0043169	cation binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/7 Sigma-Aldrich "Your Favorite Gene" Pathways for NAGA (Your Favorite Gene powered by Ingenuity) (see all 7 )

Sphingolipid Metabolism
Glycosaminoglycan Degradation
Aminosugars Metabolism
Glycerolipid Metabolism
Galactose Metabolism

GeneDecks NAGA for the pathways selected above

About GeneDecksing

5/8 Interacting proteins for NAGA (ENSP00000355349³) via UniProtKB, MINT, and/or STRING (see all 8 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HEXA	ENSP00000268097³	STRING (score=.96)
B3GALNT1	ENSP00000323479³	STRING (score=.9)
B3GALT5	ENSP00000369992³	STRING (score=.899)
NAGLU	ENSP00000225927³	STRING (score=.8)
GC	ENSP00000273951³	STRING (score=.739)

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	IEA	--
GO:0008152	metabolic process	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NAGA
6 Novoseek chemical compound relationships for NAGA gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
gal(beta1-3)galnac	62.35	1	9653936 (1)
periodate	38.35	1	9247192 (1)
n-acetylglucosamine	34.24	1	17455791 (1)
glycolipid	27.29	2	1418679 (1), 9741689 (1)
atp	0.00	1	1749310 (1)
glucose	0.00	1	10456768 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAGA)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000262

Sigma-Aldrich siRNA and siRNA Panels for NAGA

Sigma-Aldrich shRNA for NAGA

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000262

REFSEQ mRNAs for NAGA gene:

NM_000262.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000262

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000262
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000262
                                 untagged cDNA clone in CMV expression vector: NM_000262

Additional cDNA sequence:

BC000095.2 CR456527.1 CR591632.1 CR592922.1 CR595327.1 CR595848.1 CR596145.1 CR599558.1

CR601288.1 CR601521.1 CR610763.1 CR612931.1 CR618231.1 CR620776.1 CR621618.1 CR622743.1

CR623556.1 M29276.1 M38083.1 M62783.1

16 DOTS entries:

DT.100823590 DT.455140 DT.100823595 DT.100823594 DT.95107270 DT.100698611 DT.95107235 DT.100823593

DT.100643645 DT.100696225 DT.100696639 DT.100712149 DT.100719562 DT.100823598 DT.100777208 DT.95107273

24/336 AceView cDNA sequences (see all 336 ):

AA303896 AL045023 CR599558 BI769830 CR595327 BC000095 BX367373 BU170376

BX374419 CR456527 BM714265 CR596145 M38083 F03932 BX326675 AW296535

BQ645779 CB529326 CR591632 CA748937 CR623556 BM676689 CR620776 CR622743

highest scoring ESTs for NAGA:

AW382779 BC000095 BE279616 BE386881 BE409953 BE784116 BF968581 BG482168 BG829868 BI193237

Unigene Cluster for NAGA:

N-acetylgalactosaminidase, alpha-

Hs.75372 [show with all ESTs]

Unigene Representative Sequence: NM_000262

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for NAGA

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10
SP1:
SP2:							-
SP3:
SP4:													-

About this scheme

ECgene alternative splicing isoforms for NAGA

4 Ensembl transcripts including schematic representations:

ENST00000402937 ENST00000403363 ENST00000361920 ENST00000396398

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

NAGA expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NAGA

¹ / ² / ³

6 probe-sets matching NAGA gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36607_at²^{, 3}	U95-A	1	0.94	1.00	1.00	1.00	Z99716	0.20	0.50	0.38	1
202943_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	M38083	0.80	1.00	0.91	1
202944_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000262	0.60	1.00	0.82	1
202943_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
202944_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1555041_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGATTGGCTT

SOURCE GeneReport for Unigene cluster: Hs.75372
Expression variation in blood from EXPOLDB for NAGA

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NAGA gene from 5/13 species (see all 13 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NAGA¹	--	N-acetylgalactosaminidase, alpha-	87.24(n) 84.63(a)	481226 XM_538347.2 XP_538347.2
chimpanzee (Pan troglodytes)	NAGA¹	--	N-acetylgalactosaminidase, alpha-	99.59(n) 99.51(a)	470279 XM_525662.2 XP_525662.2
cow (Bos taurus)	NAGA¹	--	N-acetylgalactosaminidase, alpha-	87.51(n) 85.64(a)	533357 NM_001046349.1 NP_001039814.1
rat (Rattus norvegicus)	Naga¹	--	N-acetyl galactosaminidase, alpha	83.33(n) 82.76(a)	315165 NM_001012120.1 NP_001012120.1
mouse (Mus musculus)	Naga^{1, 5}	15 (46.00 cM)⁵	N-acetyl galactosaminidase, alpha^{1, 5}	81.83(n)¹ 82.64(a)¹	17939¹ NM_008669.3¹ NP_032695.2¹ AF079458⁵ AJ223966⁵ (see all 14)

About this table Species with no ortholog for NAGA

ENSEMBL Gene Tree for NAGA

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for NAGA gene

GLA²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/133 NCBI SNPs in NAGA are shown (see all 133 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 66)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs5758566^1,2	A,C,F,H	40784300(+)	`TACACA/GTTGAT`	1	--	ut3¹		4		EU EA WA	418
	rs133375^1,2	A,C,F,H	40796455(+)	`AGCTTC/GAGTTC`	1	--	ut5¹		14		EA NA MN EU WA	1128
--	rs2859438^1,2	A,C,F,O	40796926(+)	`GAGGCT/AGGCAT`	1	--	ng3¹		3		NA	138
	rs1063392^1,2	A,C,F,H	40784896(-)	`AAGTAT/CAGGGT`	1	--	ut3¹		17		MN EU EA WA NA	1658
	rs133377^1,2	A,C	40796896(+)	`CCCCAC/TTGGGC`	1	--	ng3¹		0	--	--	--	--
	rs2229547^1,2	C,F	40786217(-)	`GGGACA/CTGTGA`	1	--	ut3¹ ese³		4		MN NA	194
	rs133376^1,2	A,C	40796851(+)	`TGCCCC/TGCCCA`	1	--	ng3¹		0	--	--	--	--
	rs11703233^1,2	C,H	40784533(+)	`GAAGGG/ATGAAG`	1	--	ut3¹ ese³		4		EU EA WA	418
	rs17002832^1,2	F,H	40786086(+)	`TGGCCG/ATGAGA`	1	--	ut3¹ ese³		7		NA EU EA WA	562
--	rs12165638^1,2	A	40783906(+)	`ctgtcA/Gcccag`	1	--	ng5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for NAGA (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 104170 disorders: 609241 609242 609241

UniProtKB/Swiss-Prot: NAGAB_HUMAN, P17050

Defects in NAGA are the cause of Schindler disease [MIM:609241]. Schindler disease is a

form of NAGA deficiency characterized by early onset neuroaxonal dystrophy and neurological signs

(convulsion during fever, epilepsy, psychomotor retardation and hypotonia). NAGA deficiency is

typically classified in three main phenotypes: NAGA deficiency type I (Schindler disease or

Schindler disease type I) with severe manifestations; NAGA deficiency type II (Kanzazi disease or

Schindler disease type II) which is mild; NAGA deficiency type III (Schindler disease type III)

characterized by mild-to-moderate neurologic manifestations. NAGA deficiency results in the

increased urinary excretion of glycopeptides and oligosaccharides containing

alpha-N-acetylgalactosaminyl moieties. Inheritance is autosomal recessive

Defects in NAGA are the cause of Kanzaki disease [MIM:609242]; also known as NAGA

deficiency type II or Schindler disease type II. Kanzaki disease is an autosomal recessive

disorder characterized by late onset, angiokeratoma corporis diffusum and mild intellectual

impairment

10/16 Novoseek disease relationships for NAGA gene (see all 16 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neuroaxonal dystrophies	91.96	5	8466216 (1), 2122121 (1), 11313741 (1), 1907616 (1) (see all 5)
neuroaxonal dystrophy, infantile	89.91	4	1907616 (2), 2122121 (1)
angiokeratoma	82.50	3	7707696 (1), 1907616 (1)
fucosidosis	82.19	4	10571005 (2), 2208741 (1), 2122119 (1)
fabry disease	80.34	7	11251574 (2), 2208741 (2), 2160280 (1), 8040340 (1) (see all 5)
lysosomal storage diseases	69.45	3	11251574 (1), 7707696 (1), 2208741 (1)
sialidosis	67.39	2	2208741 (1), 2122119 (1)
enzyme deficiency	57.99	1	8466216 (1)
deficiency diseases	57.20	1	12005440 (1)
nephropathy iga	50.67	1	18925530 (1)

About this table

Genatlas disease: NAGA

angiokeratoma corporis diffusum with glycopeptiduria,Schindler,Seitelberger disease,neuroaxonal

dystrophy,infantile and adult types

Human Gene Mutation Database: NAGA

(Possibly Related Articles in Doctor's Guide)
About This Section

AASLD: MELD not Superior to Child-Pugh for Predicting Outcome of Acute Variceal Bleeding

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/113 PubMed articles for NAGA gene (see all 113 ):

Molecular cloning of two species of cDNAs for human alpha-N- acetylgalactosaminidase and expression in mammalian cells. (PubMed id 2372288)^{1, 3, 4} Yamauchi T.... Tsuji S. (1990)
A new case of alpha-N-acetylgalactosaminidase deficiency with angiokeratoma corporis diffusum, with Meniere's syndrome and without mental retardation. (PubMed id 11251574)^{1, 3, 4} Kodama K.... Kanzaki T. (2001)
Human alpha-N-acetylgalactosaminidase (alpha-NAGA) deficiency: new mutations and the paradox between genotype and phenotype. (PubMed id 8782044)^{1, 3, 4} Keulemans J.L.M.... van Diggelen O.P. (1996)
The molecular lesion in the alpha-N-acetylgalactosaminidase gene that causes angiokeratoma corporis diffusum with glycopeptiduria. (PubMed id 8040340)^{1, 3, 4} Wang A.M.... Desnick R.J. (1994)
Structural organization and complete sequence of the human alpha-N- acetylgalactosaminidase gene: homology with the alpha-galactosidase A gene provides evidence for evolution from a common ancestral gene. (PubMed id 1646157)^{1, 3, 4} Wang A.M. and Desnick R.J. (1991)
Human alpha-N-acetylgalactosaminidase-molecular cloning, nucleotide sequence, and expression of a full-length cDNA. Homology with human alpha-galactosidase A suggests evolution from a common ancestral gene. (PubMed id 2174888)^{1, 3, 4} Wang A.M.... Desnick R.J. (1990)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{3, 4} Collins J.E.... Dunham I. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{3, 4} Dunham I....O'Brien K.P. (1999)
Photolabeling of the alpha-neuraminidase/beta-galactosidase complex from human placenta with a photoreactive neuraminidase inhibitor. (PubMed id 2256909)^{3, 4} Warner T.G.... Potier M. (1990)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4668	HGNC: 7631	AceView: NAGA	Ensembl:ENSG00000198951	euGenes: HUgn4668
ECgene: NAGA	H-InvDB: NAGA

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
GeneReviews	http://www.genetests.org/query?gene=NAGA

Licensable Technologies for NAGA
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for NAGA:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NAGA-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NAGA		Antibodies for NAGA
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for NAGA		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (NAGA)
	Antibodies (NAGA)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (NAGA)
	Antibodies (NAGA)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for NAGA

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for NAGA

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
NAGA Gene at Home site.
Version 2.41.1
server5.xennexinc.com

NAGA Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for NAGA

Summaries
for NAGA

Genomic Location
for NAGA

Proteins
for NAGA

Protein Domains/
Families
for NAGA

Gene Function
for NAGA

Pathways & Interactions
for NAGA

Drugs & Compounds
for NAGA

Transcripts
for NAGA

Expression
for NAGA

Orthologs
for NAGA

Paralogs
for NAGA

SNPs/Variants
for NAGA

Disorders & Mutations
for NAGA

Medical News
for NAGA

Publications
for NAGA

Search for NAGA

Genome Databases showing NAGA

Other Databases showing NAGA

Specialized Databases showing NAGA

Licensable Technologies
for NAGA

Services
for NAGA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NAGA Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor NAGA

Summariesfor NAGA

Genomic Locationfor NAGA

Proteinsfor NAGA

Protein Domains/Familiesfor NAGA

Gene Functionfor NAGA

Pathways & Interactionsfor NAGA

Drugs & Compoundsfor NAGA

Transcriptsfor NAGA

Expression for NAGA

Orthologsfor NAGA

Paralogsfor NAGA

SNPs/Variantsfor NAGA

Disorders & Mutationsfor NAGA

Medical Newsfor NAGA

Publicationsfor NAGA

Search for NAGA

Genome Databases showing NAGA

Other Databases showing NAGA

Specialized Databases showing NAGA

Licensable Technologiesfor NAGA

Servicesfor NAGA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NAGA

Summaries
for NAGA

Genomic Location
for NAGA

Proteins
for NAGA

Protein Domains/
Families
for NAGA

Gene Function
for NAGA

Pathways & Interactions
for NAGA

Drugs & Compounds
for NAGA

Transcripts
for NAGA

Expression
for NAGA

Orthologs
for NAGA

Paralogs
for NAGA

SNPs/Variants
for NAGA

Disorders & Mutations
for NAGA

Medical News
for NAGA

Publications
for NAGA

Licensable Technologies
for NAGA

Services
for NAGA