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NACC2 Gene

protein-coding   GIFtS: 45
GCID: GC09M138898

NACC Family Member 2, BEN And BTB (POZ) Domain Containing

(Previous name: BTB (POZ) domain containing 14A)
(Previous symbol: BTBD14A)
  Search for NACC2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NACC Family Member 2, BEN And BTB (POZ) Domain Containing1 2     BTBD142
BTBD14A1 2 3     BTBD312
BTB (POZ) Domain Containing 14A1 2     RBB2
BEN Domain Containing 91 2     Nucleus Accumbens-Associated Protein 22
NAC-22 3     Transcription Repressor With A BTB Domain And A BEN Domain2
BTB/POZ Domain-Containing Protein 14A2 3     NAC23
BEND92     

External Ids:    HGNC: 238461   Entrez Gene: 1381512   Ensembl: ENSG000001484117   UniProtKB: Q96BF63   

Export aliases for NACC2 gene to outside databases

Previous GC identifers: GC09M138039 GC09M108365


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NACC2 Gene:
NACC2 (NACC family member 2, BEN and BTB (POZ) domain containing) is a protein-coding gene. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding and protein homodimerization activity. An important paralog of this gene is ZBTB34.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the NACC2 gene promoter:
         STAT5B   STAT1   STAT4   STAT6   STAT1beta   STAT1alpha   CREB   deltaCREB   STAT2   STAT3   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NACC2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NACC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

NACC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NACC2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M138898:  view genomic region     (about GC identifiers)

Start:
138,898,383 bp from pter      End:
138,987,131 bp from pter
Size:
88,749 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NACC2_HUMAN, Q96BF6 (See protein sequence)
Recommended Name: Nucleus accumbens-associated protein 2  
Size: 587 amino acids; 62837 Da

Explore the universe of human proteins at neXtProt for NACC2: NX_Q96BF6

Explore proteomics data for NACC2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NACC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_653254.1  
    ENSEMBL proteins: 
     ENSP00000360818   ENSP00000277554  

    NACC2 Human Recombinant Protein Products:

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    Novus Biologicals NACC2 Protein
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for NACC2 

    NACC2 Antibody Products:

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    Search for Antibodies for NACC2 at Abcam
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    LSBio Antibodies in human, mouse, rat for NACC2

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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for NACC2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BEND: BEN domain containing
    BTBD: BTB/POZ domain containing

    4 InterPro protein domains:
     IPR018379 BEN_domain
     IPR000210 BTB/POZ-like
     IPR011333 BTB/POZ_fold
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry Q96BF6

    ProtoNet protein and cluster: Q96BF6

    UniProtKB/Swiss-Prot: NACC2_HUMAN, Q96BF6
    Similarity: Contains 1 BEN domain
    Similarity: Contains 1 BTB (POZ) domain


    Find genes that share domains with NACC2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA--
    GO:0001076RNA polymerase II transcription factor binding transcription factor activity IDA--
    GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription IDA--
    GO:0004407histone deacetylase activity IDA--
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with NACC2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NACC2:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NACC2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NACC2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NACC2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NACC2

    miRNA
    Products:
        
    miRTarBase miRNAs that target NACC2:
    hsa-mir-30b-5p (MIRT023430), hsa-mir-130b-3p (MIRT020125), hsa-mir-92a-3p (MIRT049121), hsa-mir-92b-3p (MIRT040661), hsa-mir-423-3p (MIRT016683), hsa-mir-10a-5p (MIRT047631), hsa-mir-19b-3p (MIRT031107), hsa-mir-26b-5p (MIRT028773), hsa-mir-93-5p (MIRT027987)

    Block miRNA regulation of human, mouse, rat NACC2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NACC2 (see all 150):
    hsa-miR-194* hsa-miR-106a hsa-miR-199a-3p hsa-miR-128 hsa-miR-3921 hsa-miR-519a hsa-miR-1273d hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidNACC2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NACC2
    Predesigned siRNA for gene silencing in human, mouse, rat NACC2

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: NACC2 (NM_144653)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NACC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NACC2

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACC2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2
    endoplasmic reticulum1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000790nuclear chromatin IDA--
    GO:0005634nucleus ISS--
    GO:0016581colocalizes with NuRD complex IDA--
    GO:0016604nuclear body ISS--

    Find genes that share ontologies with NACC2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NACC2
    Interactions:

        Search GeneGlobe Interaction Network for NACC2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for NACC2 (Q96BF63 ENSP000002775544) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NACC1Q96RE73, ENSP000002924314I2D: score=2 STRING: ENSP00000292431
    UBE2IENSP000003248974STRING: ENSP00000324897
    ZBTB17ENSP000003648954STRING: ENSP00000364895
    SLX1AENSP000002513034STRING: ENSP00000251303
    SLX1BENSP000003289404STRING: ENSP00000328940
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006366transcription from RNA polymerase II promoter IDA--
    GO:0008284positive regulation of cell proliferation ISS--
    GO:0008285negative regulation of cell proliferation IDA--
    GO:0010608posttranscriptional regulation of gene expression IMP--
    GO:0016575histone deacetylation IDA--

    Find genes that share ontologies with NACC2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NACC2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NACC2 gene: 
    NM_144653.4  

    Unigene Cluster for NACC2:

    NACC family member 2, BEN and BTB (POZ) domain containing
    Hs.112895  [show with all ESTs]
    Unigene Representative Sequence: NM_144653
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371753(uc004cgv.4 uc010nbh.3) ENST00000467669 ENST00000277554

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NACC2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NACC2 (see all 150):
    hsa-miR-194* hsa-miR-106a hsa-miR-199a-3p hsa-miR-128 hsa-miR-3921 hsa-miR-519a hsa-miR-1273d hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidNACC2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NACC2
    Predesigned siRNA for gene silencing in human, mouse, rat NACC2
    Clone
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    OriGene clones in human, mouse for NACC2 (see all 6)
    OriGene ORF clones in mouse, rat for NACC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NACC2 (NM_144653)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NACC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NACC2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NACC2
    OriGene qSTAR qPCR primer pairs in human, mouse for NACC2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NACC2
      QuantiTect SYBR Green Assays in human, mouse, rat NACC2
      QuantiFast Probe-based Assays in human, mouse, rat NACC2

    Additional mRNA sequence: 

    AK055078.1 AK056521.1 AK094914.1 AK308497.1 AK309247.1 AK311634.1 AL832276.1 BC015649.2 
    BC045702.1 

    5 DOTS entries:

    DT.312270  DT.308796  DT.75101753  DT.40106727  DT.65287577 

    Selected AceView cDNA sequences (see all 55):

    AI336998 CA425918 BM795567 BM714009 AI989498 BI823351 AW237064 BQ929493 
    NM_144653 BC015649 AI917857 BM550374 BU689592 BF940160 AI184528 BQ220455 
    AI380814 BX331874 BX369734 AI218896 AI806391 BX110449 AI741885 BQ083066 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NACC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NACC2 Expression
    About this image


    NACC2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Eye (Sensory Organs)
             Retina
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Spinal Cord (Nervous System)
    NACC2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NACC2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.112895
        Custom PCR Arrays for NACC2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NACC2 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nacc21 , 5 nucleus accumbens associated 2, BEN and BTB (POZ) domain more1, 5 86.36(n)1
    93.32(a)1
      2 (18.29 cM)5
    679911  NM_026495.31  NP_080771.31 
     260555355 
    chicken
    (Gallus gallus)
    Aves NACC21 NACC family member 2, BEN and BTB (POZ) domain containing 80.79(n)
    85.42(a)
      417128  NM_001030681.1  NP_001025852.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nacc21 NACC family member 2, BEN and BTB (POZ) domain containing 74.99(n)
    79.93(a)
      100125188  NM_001103074.1  NP_001096544.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5595201 nucleus accumbens-associated protein 2-like 67.59(n)
    63.54(a)
      559520  XM_005172027.1  XP_005172084.1 


    ENSEMBL Gene Tree for NACC2 (if available)
    TreeFam Gene Tree for NACC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NACC2 gene
    ZBTB342  ZBTB222  NACC12  ZBTB452  ZBTB62  ZBTB92  ZBTB262  ZBTB432  
    ZBTB372  ZBTB122  ZBTB202  
    1 SIMAP similar gene for NACC2 using alignment to 1 protein entry:     NACC2_HUMAN:
    NACC1

    Find genes that share paralogs with NACC2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for NACC2
    PGOHUM00000244444


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NACC2 (see all 1894)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs345144331,2
    C--108380500(+) AAAAA-/A/AAA 
            
    GATAA
    1 -- int11NA 2
    rs78748681,2
    C,A--138898003(+) GGTGAG/AGCAGA 1 -- ds50014Minor allele frequency- A:0.05CSA WA NA EA 360
    rs78758931,2
    C,F,A,H--138898063(+) GAGACC/TCCCCG 1 -- ds50018Minor allele frequency- T:0.03NS EA WA NA 752
    rs1151839721,2
    C,F--138898087(+) GCCTGC/TGGGTC 1 -- ds50011Minor allele frequency- T:0.09WA 118
    rs107768661,2
    C,F,A,H--138898172(+) CACTGA/GGGAGA 1 -- ds500128Minor allele frequency- G:0.49NS EA NA WA CSA 2777
    rs111032621,2
    C,F,H--138898254(+) GGGACG/ACCGCT 1 -- ds500117Minor allele frequency- A:0.12NS EA NA WA 2158
    rs1468415011,2
    --138898265(+) AACAGG/TGACGG 1 -- ds50010--------
    rs795632301,2
    C--138898317(+) CTTCAA/GTAGCC 1 -- ds50010--------
    rs1444070981,2
    --138898415(+) GTAAAC/TGTGAA 1 -- ut310--------
    rs1452274481,2
    --138898514(+) CCCTCA/GGTTTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NACC2 (138898383 - 138987131 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for NACC2 (see all 38):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2739319CNV Deletion23290073
    esv2739318CNV Deletion23290073
    esv2739320CNV Deletion23290073
    dgv1387e199CNV Deletion23128226
    esv2676603CNV Deletion23128226
    nsv415943CNV Insertion16902084
    esv1257856CNV Insertion17803354
    nsv415932CNV Insertion16902084
    nsv6761CNV Insertion18451855
    nsv509332CNV Insertion20534489

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NACC2
    DNA2.0 Custom Variant and Variant Library Synthesis for NACC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with NACC2           About GenesLikeMe

    Genetic Association Database (GAD): NACC2
    Human Genome Epidemiology (HuGE) Navigator: NACC2 (1 document)

    Export disorders for NACC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NACC2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NACC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene. (PubMed id 22926524)1 Xuan C....Shang Y. (Oncogene 2013)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)
    9. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H.... Kim N.S. (Mamm. Genome 2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 138151 HGNC: 23846 AceView: BTBD14A Ensembl:ENSG00000148411 euGenes: HUgn138151
    ECgene: NACC2 H-InvDB: NACC2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NACC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NACC2 gene:
    Search GeneIP for patents involving NACC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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