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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NACAD Gene

protein-coding   GIFtS: 42
GCID: GC07M045120

NAC Alpha Domain Containing

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NAC Alpha Domain Containing1 2
NAC-Alpha Domain-Containing Protein 12
KIAA03633

External Ids:    HGNC: 221961   Entrez Gene: 231482   Ensembl: ENSG000001362747   UniProtKB: O150693   

Export aliases for NACAD gene to outside databases

Previous GC identifers: GC07M045087 GC07M045067 GC07M045004


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NACAD Gene: 
NACAD (NAC alpha domain containing) is a protein-coding gene. Diseases associated with NACAD include cblc. An important paralog of this gene is NACA.

UniProtKB/Swiss-Prot: NACAD_HUMAN, O15069
Function: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May
bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal
recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the
inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NACAD gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   NF-kappaB   HEN1   PPAR-gamma1   E2F-1   E2F   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for NACAD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NACAD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p13   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13

NACAD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NACAD gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M045120:  view genomic region     (about GC identifiers)

Start:
45,120,036 bp from pter      End:
45,128,513 bp from pter
Size:
8,478 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 45,159,326-45,167,663     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NACAD_HUMAN, O15069 (See protein sequence)
Recommended Name: NAC-alpha domain-containing protein 1  
Size: 1562 amino acids; 161101 Da
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)

Explore the universe of human proteins at neXtProt for NACAD: NX_O15069

Explore proteomics data for NACAD at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O15069

  • NACAD Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NACAD Protein Expression
    REFSEQ proteins: NP_001139806.1  
    ENSEMBL proteins: 
     ENSP00000420477  

    Human Recombinant Protein Products for NACAD: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for NACAD
    GenScript Custom Purified and Recombinant Proteins Services for NACAD
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    NACAD for ontologies           About GeneDecksing



    NACAD Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
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    OriGene Custom Antibody Services for NACAD
    GenScript Custom Superior Antibodies Services for NACAD
    Novus Biologicals NACAD Antibody
    Search for Antibodies for NACAD at Abcam
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for NACAD
    LSBio Antibodies in human, mouse, rat for NACAD 

    Assay Products for NACAD: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NACAD
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NACAD
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR016641 EGD2/NACA
     IPR002715 Nas_poly-pep-assoc_cplx_dom

    Graphical View of Domain Structure for InterPro Entry O15069

    ProtoNet protein and cluster: O15069

    UniProtKB/Swiss-Prot: NACAD_HUMAN, O15069
    Similarity: Belongs to the NAC-alpha family
    Similarity: Contains 1 NAC-A/B (NAC-alpha/beta) domain


    NACAD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NACAD_HUMAN, O15069
    Function: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May
    bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal
    recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the
    inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for NACAD:

     Decreased cell number and incr 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NACAD 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NACAD

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NACAD 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NACAD 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NACAD
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NACAD
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NACAD
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NACAD

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NACAD
    Sirion Biotech Customized adenovirus for overexpression of NACAD

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NACAD (see all 5)
    OriGene ORF clones in mouse, rat for NACAD
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NACAD (NM_001146334)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NACAD
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NACAD

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NACAD
    Search LifeMap BioReagents cell lines for NACAD
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACAD


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NACAD

    5/8 Interacting proteins for NACAD (O150692, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBLCQ9ULV82, 3MINT-8250690 I2D: score=2 
    HDAC6Q9UBN72, 3MINT-8258054 I2D: score=2 
    MAP4K2Q128512, 3MINT-8260438 I2D: score=2 
    NR4A1P227362, 3MINT-8264072 I2D: score=2 
    PTK2Q053972, 3MINT-8267605 I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--

    NACAD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NACAD

    Search CenterWatch for drugs/clinical trials and news about NACAD

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NACAD gene: 
    NM_001146334.1  

    Unigene Cluster for NACAD:

    NAC alpha domain containing
    Hs.96633  [show with all ESTs]
    Unigene Representative Sequence: NM_001146334
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000490531(uc003tmt.3) ENST00000460409
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NACAD
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NACAD
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NACAD
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NACAD
    Clone
    Products:
         
    OriGene clones in human, mouse for NACAD (see all 5)
    OriGene ORF clones in mouse, rat for NACAD
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NACAD (NM_001146334)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NACAD
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NACAD
    Primer
    Products:
        
    Browse OriGene qPCR
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NACAD
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NACAD
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NACAD

    Additional mRNA sequence: AB002361.1 

    3 DOTS entries:

    DT.109423  DT.100658926  DT.97787649 

    24/64 AceView cDNA sequences (see all 64):

    AA297699 AB002361 CD675048 BM727592 BF528737 BM728120 BM680676 AL119753 
    BM723495 BE645604 BM681033 BU855107 BM047267 BM696401 AV726228 BU859196 
    AW206432 BM700205 BM313707 CK905158 BX411309 BP431048 BU682625 BU543827 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NACAD expression in normal human tissues (normalized intensities)      NACAD embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCCACTGA
    NACAD Expression
    About this image


    NACAD expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             ganglion/cranial/facial VII   
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 2 entries
             autonomic/sympathetic/ganglion   
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 2 entries
             Midgut
     
     Eye (Sensory Organs)
             Retina
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See NACAD Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NACAD

    SOURCE GeneReport for Unigene cluster: Hs.96633
        SABiosciences Custom PCR Arrays for NACAD
    Primer
    Products:
    Browse OriGene qPCR
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NACAD
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NACAD
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NACAD
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACAD

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NACAD gene from 10/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nacad1 , 5 NAC alpha domain containing1, 5 68.41(n)1
    58.88(a)1
      11 (4.60 cM)5
    1929501  NM_001081652.11  NP_001075121.11 
     65978235 
    chicken
    (Gallus gallus)
    Aves NACAD1 NAC alpha domain containing 47.42(n)
    36.15(a)
      420409  XM_418516.3  XP_418516.3 
    lizard
    (Anolis carolinensis)
    Reptilia NACAD6
    Uncharacterized protein
    65(a)
    1 ↔ 1
    AAWZ02040392(2124-3349)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.321732 Xenopus laevis transcribed sequence with moderate similarity more 82.68(n)    BJ641912.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nacad6
    NAC alpha domain containing
    17(a)
    1 ↔ 1
    16(29852634-29869234)
    fruit fly
    (Drosophila melanogaster)
    Insecta Nacalpha6
    CG44156
    --
    48(a)
    25(a)
    many ↔ many
    many ↔ many
    2R(8647198-8648377)
    2L(1037246-1038685)
    worm
    (Caenorhabditis elegans)
    Secernentea icd-26
    Nascent polypeptide-associated complex subunit alp...
    46(a)
    1 → many
    I(535789-536670)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes EGD26
    Alpha subunit of the heteromeric nascent polypepti...
    36(a)
    1 → many
    VIII(487712-488236)
    soybean
    (Glycine max)
    eudicotyledons 467218022   -- 73.11(n)  
    rice
    (Oryza sativa)
    Liliopsida Os.90742 Oryza sativa (japonica cultivar-group) isolate 20527 more 77.36(n)    AK099300.1 


    ENSEMBL Gene Tree for NACAD (if available)
    TreeFam Gene Tree for NACAD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NACAD gene
    NACA2  NACA22  
    3 SIMAP similar genes for NACAD using alignment to 1 protein entry:     NACAD_HUMAN:
    NACA    NACAP1    NACA2

    NACAD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/180 SNPs in NACAD are shown (see all 180)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1480819011,2
    --45121817(+) AGATCG/TGCAAG 2 Q P mis10--------
    rs1121564231,2
    C--45121848(+) GGAGGT/CCACCT 2 /T /A mis11Minor allele frequency- C:0.00CSA 1
    rs1814267021,2
    --45121864(+) CTGAGA/GAGTGG 2 L syn10--------
    rs1866793751,2
    --45122188(+) CTGGGC/TACTTC 2 V syn10--------
    rs37354931,2,4
    C,F,A,H--45122324(+) CTGGGC/AAGGAG 2 /C /F mis1 ese321Minor allele frequency- A:0.09EA NS NA 3760
    rs102431851,2,4
    C,F,A,H--45122464(+) GGCGCA/CTCGGG 2 E D mis1 ese315Minor allele frequency- C:0.43NA EA NS WA CSA EU 1048
    rs2006781801,2
    C--45122472(+) GGGGAC/GCTCCC 2 L V mis10--------
    rs1903389401,2
    --45122601(+) ACCTGG/TGTGCG 2 T P mis10--------
    rs1140894811,2
    C,F--45122611(+) GCTCGC/AGCTTC 2 /A syn11Minor allele frequency- A:0.03WA 118
    rs1135588751,2
    C,F--45122612(+) CTCGCG/ACTTCC 2 /A /V mis11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for NACAD (45120036 - 45128513 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NACAD:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1076637CNV Deletion17803354
    nsv888001CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing NACAD
    DNA2.0 Custom Variant and Variant Library Synthesis for NACAD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for NACAD:    About MalaCards
    cblc    


    NACAD for disorders           About GeneDecksing


    Export disorders for NACAD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NACAD gene integrated from 9 sources:
    (articles sorted by number of sources associating them with NACAD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    2. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    4. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23148 HGNC: 22196 AceView: KIAA0363 Ensembl:ENSG00000136274 euGenes: HUgn23148
    ECgene: NACAD H-InvDB: NACAD

    (According to HUGE)
    About This Section
    HUGE: KIAA0363

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NACAD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NACAD gene:
    Search GeneIP for patents involving NACAD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     OriGene Custom Antibody Services for NACAD   OriGene Custom Protein Services for NACAD  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NACAD
     QIAGEN SeqTarget long-range PCR primers for resequencing NACAD
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NACAD
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NACAD
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     GenScript Custom Purified and Recombinant Proteins Services for NACAD GenScript cDNA clones with any tag delivered in your preferred vector for NACAD
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     Search for Antibodies & Assays

     Regulatory tfbs in NACAD promoter
     Search Chromatin IP Primers for NACAD
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     Search Tocris compounds for NACAD
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
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     Search Sino Biological for antibodies, proteins & pathways
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
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     Search for Antibodies for NACAD at Abcam
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     Browse Proteins at Cloud-Clone Corp.
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     Search LifeMap BioReagents cell lines for NACAD
     Gene Synthesis
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     Search ThermoFisher Antibodies for NACAD
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NACAD
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NACAD
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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