NACA Gene
protein-coding GIFtS: 54
GCID: GC12M057106
|
|
nascent polypeptide-associated complex alpha subunit(Previous name: nascent-polypeptide-associated complex alpha polypeptide...)
| |
Aliases
for NACA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nascent Polypeptide-Associated Complex Alpha Subunit1 2 | | Alpha-NAC3 | | NACA11 2 | | Nascent Polypeptide-Associated Complex Subunit Alpha2 | | Nascent-Polypeptide-Associated Complex Alpha Polypeptide1 2 | | Alpha-NAC3 | | NAC-Alpha1 | | Allergen Hom S 23 |
Export aliases for NACA gene to outside databasesPrevious GC identifers: GC12M057078 GC12M057330 GC12M056820 GC12M055392 GC12M054144 |
Summaries
for NACA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NACA:
The protein encoded by this gene associates with basic transcription factor 3 (BTF3) to form the nascentpolypeptide-associated complex (NAC). NAC binds to nascent proteins as they emerge from the ribosome, blockinginteraction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum.However, nascent proteins with an exposed signal peptide will not be bound by the encoded protein, enabling them tobind the SRP and enter the secretory pathway. This protein has been determined to be an IgE autoantigen in atopicdermatitis patients. Several transcript variants encoding two different isoforms have been found for this gene.(provided by RefSeq, Oct 2011)
UniProtKB/Swiss-Prot: NACA_HUMAN, Q13765Function: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds tonascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognitionparticle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity ofribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN,binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters
Gene Wiki entry for NACA
|
Genomic Views
for NACA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NACA gene promoter:
GR GR-beta ATF-2 GR-alpha c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for NACA
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NACA |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q23-q24.1 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q23-q24.1NACA Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M057106: view genomic region
(about GC identifiers)
Start:
|
57,106,211 bp from pter |
End:
|
57,125,412 bp from pter |
Size:
|
19,202 bases |
Orientation:
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minus strand |
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Proteins
for NACA gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NACA_HUMAN, Q13765 (See
protein sequence)Recommended Name: Nascent polypeptide-associated complex subunit alpha Size: 215 amino acids; 23384 Da
Subunit: Interacts with TBP and JUN (By similarity). Part of the nascent polypeptide-associated complex (NAC),consisting of NACA and BTF3. NAC associates with ribosomes through the BTF3 subunit. Both subunits can contact nascentpolypeptide chains. Interacts with ASFV protein H339R
Subcellular location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus
Allergen: Causes an allergic reaction in human. Binds to IgE from atopic dermatitis (AD) patients. Identified as an IgEautoantigen in atopic dermatitis (AD) patients with severe skin manifestations
Sequence caution: Sequence=AAV83778.1; Type=Erroneous initiation;
3 PDB 3D structures from  and Proteopedia  for NACA:3LKX (3D)
3MCB (3D)
3MCE (3D)
Secondary accessions: F8VU71 Q3KQV4 Q53A18 Q53G46Alternative splicing: 2 isoforms: Q13765-1 Q13765-2 (No experimental confirmation available. May be due to intron retention)Explore the universe of human proteins at neXtProt for NACA: NX_Q13765
Post-translational modifications:
Phosphorylation of Thr-159 by GSK3B may promote proteasome mediated degradation (By similarity). Phosphorylation ofSer-43 by ILK during cell adhesion may promote nuclear localization1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13765
NACA Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001106673.1 NP_001106674.2
ENSEMBL proteins: ENSP00000448039 ENSP00000448035 ENSP00000349212 ENSP00000447821 ENSP00000377469 ENSP00000447705 ENSP00000446801 ENSP00000446745 ENSP00000447133 ENSP00000450383 ENSP00000446933 ENSP00000447764 ENSP00000447207 ENSP00000447666 ENSP00000403817
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NACA for ontologies About GeneDecksing
NACA Antibody Products:
Assay Products for NACA: |
Protein
Domains /
Families
for NACA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NACA for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13765ProtoNet protein and cluster: Q13765 UniProtKB/Swiss-Prot: NACA_HUMAN, Q13765Similarity: Belongs to the NAC-alpha familySimilarity: Contains 1 NAC-A/B (NAC-alpha/beta) domainSimilarity: Contains 1 UBA domain |
Function
for NACA gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NACA_HUMAN, Q13765Function: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds tonascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognitionparticle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity ofribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN,binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters Genatlas biochemistry entry for NACA:nascent polypeptide-associated complex A/1.9.2,with two alternatively spliced isoform,acting as a muscle specificisoform
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NACA (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NACA (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): NACA (NM_005594) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NACA | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NACA |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACA |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
NACA for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for NACA:
Animal Models:
8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Naca):
NACA for phenotypes About GeneDecksing
|
Pathways & Interactions
for NACA gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Rho Family GTPases | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for NACA
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NACA
STRING Interaction
Network Preview (showing 5 interactants - click image to see 17)
5/49 Interacting proteins for NACA (Q137651, 2, 3 ENSP000004038174) via UniProtKB, MINT, STRING, and/or I2D (see all 49)About this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table
NACA for ontologies About GeneDecksing
|
Drugs & Compounds
for NACA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NACA
Search CenterWatch for drugs/clinical trials and news about NACA
|
Transcripts
for NACA gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NACA gene (4 alternative transcripts): NM_001113202.1 NM_001113203.2 NM_001113201.1 NM_005594.4 Unigene Cluster for NACA: Nascent polypeptide-associated complex alpha subunit Hs.505735 [show with all ESTs]Unigene Representative Sequence: NM_00111320318/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000550920 ENST00000550952 ENST00000356769 ENST00000552540(uc001slz.2)
ENST00000393891(uc001sly.2) ENST00000548386 ENST00000548563 ENST00000546392
ENST00000547914 ENST00000546410 ENST00000549259 ENST00000551775 ENST00000552055
ENST00000546862 ENST00000549855 ENST00000551793 ENST00000551520 ENST00000550343
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NACA (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NACA (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): NACA (NM_005594) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NACA | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NACA |
Additional cDNA sequence: AF054187.1 AK090650.1 AK096699.1 AK223085.1 AK293209.1 AK311904.1 AY034001.1 AY605660.1 AY911673.1 BC105120.1 BC105122.1 BC106041.1 CR450295.1 NR_045277.1 X80909.1 24/75 DOTS entries (see all 75): DT.100889874 DT.91783886 DT.91733258 DT.97868164 DT.91840150 DT.91718355 DT.95228035 DT.121209295 DT.100889890 DT.452984 DT.100889895 DT.91783876 DT.121209326 DT.121209266 DT.121209229 DT.95228084 DT.121232286 DT.100889896 DT.92056217 DT.121209132 DT.95228072 DT.121209279 DT.86993099 DT.100889884 24/1512 AceView cDNA sequences (see all 1512): BI858408 BP870848 BU182929 CR624198 CB145420 BQ927672 BF062248 BE277036 BU931152 BF831024 BG034283 CR626308 AA328389 BM855187 T54741 CR595197 BM543012 AW406434 CD677442 BE275217 AA025972 BG575016 BM700502 BU634053
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for NACA (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | - | | | | |
| SP2: | | | | | - | | - | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NACA
|
Expression
for NACA gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NACA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCACAAGCAA
About this image
See NACA Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NACA
SOURCE GeneReport for Unigene cluster: Hs.505735
UniProtKB/Swiss-Prot: NACA_HUMAN, Q13765Tissue specificity: Ubiquitously expressed
SABiosciences Custom PCR Arrays for NACA
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NACA
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NACA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NACA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NACA | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACA |
Orthologs
for NACA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NACA gene from 9/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Naca5 |
nascent polypeptide-associated complex alpha polypeptide |
-- |
|
10 (76.39 cM) 128035346 |
chicken
(Gallus gallus) |
Aves |
NACA1 |
nascent polypeptide-associated complex alpha subunit |
73.17(n)
80.5(a) |
|
396544 XM_424297.3 XP_424297.3 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
97(a) |
1 → many |
GL343463.1(1862-7785) |
zebrafish
(Danio rerio) |
Actinopterygii |
naca6 |
nascent polypeptide-associated complex alpha polyp... |
95(a) |
1 → many |
23(18036671-18045059) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Nacalpha1 , 3 |
Nascent polypeptide associated complex protein alpha more1 |
58(a)3
57.81(n)1
63.77(a)1 |
|
2 49D23
364091 NM_057868.31 NP_477216.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y65B4BR.51 |
Protein Y65B4BR.5 |
60.95(n)
64(a) |
|
171646 NM_182046.5 NP_871846.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
EGD21 |
Egd2p |
53.38(n)
44.76(a) |
|
856600 NP_012063.3 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NACA21 |
nascent polypeptide-associated complex subunit alpha-like more |
58.29(n)
56.42(a) |
|
824109 NM_114807.4 NP_190516.1 |
rice
(Oryza sativa) |
Liliopsida |
Os03g01217001 |
hypothetical protein |
51.98(n)
50.99(a) |
|
4331439 NM_001055330.1 NP_001048795.1 |
ENSEMBL Gene Tree for NACA (if available)
TreeFam Gene Tree for NACA (if available) |
Paralogs
for NACA gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NACA gene
- NACAD2 NACA22
3 SIMAP similar genes for NACA using alignment to 10 protein entries: NACA_HUMAN (see all proteins):NACA2 NACAP1 NACAD
NACA for paralogs About GeneDecksing
5/7 Pseudogenes.org Pseudogenes for NACA (see all 7)
PGOHUM00000238640 PGOHUM00000239545 PGOHUM00000261350 PGOHUM00000245476 PGOHUM00000250798
|
Genomic Variants
for NACA gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NACA (57106211 - 57125412 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for NACA
8 CNVs: 86397 76054 76051 71518 86395 86396 76053 76052
1 Indel: 45060 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NACA |
|
Disorders
/ Diseases
for NACA gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NACA for disorders About GeneDecksing
OMIM gene information: 601234
OMIM disorders: --
20/26  diseases for NACA (see all 26): About MalaCardsatopic dermatitis lethal midline granuloma dermatitis juvenile myelomonocytic leukemia
myelomonocytic leukemia papillary thyroid carcinoma tuberous sclerosis folliculitis
ulcerative colitis hepatitis b thyroid carcinoma down syndrome
thyroiditis breast adenocarcinoma hepatocellular carcinoma alzheimer's disease
hepatitis leukemia osteosarcoma adenocarcinoma
1 disease from the University of Copenhagen DISEASES database for NACA:Narcolepsy 2 Novoseek disease relationships for NACA gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hepatitis b |
10.4 |
1 |
15986874 (1) |
| tumors |
0 |
1 |
9202657 (1) |
Export disorders for NACA gene to outside databases
|
Publications
for NACA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NACA gene, integrated from 9 sources (see all 80):
(articles sorted by number of sources associating them with NACA) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- NACA is a positive regulator of human erythroid-cell differentiation. (PubMed id 15784678)1, 2, 9 Lopez S....Gomez S. (2005)
- Investigation of alpha nascent polypeptide-associated complex functions in a human CD8(+) T cell ex vivo expansion model using antisense oligonucleotides. (PubMed id 15196207)1, 2, 9 Al-Shanti N.... Rowbottom A.W. (2004)
- Activation of the JNK-AP-1 signal transduction pathway is associated with pathogenesis and progression of human osteosarcomas. (PubMed id 12689679)1, 2, 9 Papachristou D.J....Papavassiliou A.G. (2003)
- Emergence of young human genes after a burst of retroposition in primates. (PubMed id 16201836)1, 2 Marques A.C.... Kaessmann H. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The alpha-chain of the nascent polypeptide-associated complex binds to and regulates FADD function. (PubMed id 12684039)1, 2 Stilo R.... Vito P. (2003)
- Novel products of the HuD, HuC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library. (PubMed id 12209604)1, 2 Behrends U.... Mautner J.M. (2002)
- The alpha and beta subunit of the nascent polypeptide-associated complex have distinct functions. (PubMed id 10982809)1, 2 Beatrix B.... Wiedmann M. (2000)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
|
External Searches for NACA gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NACA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NACA gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NACA gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for NACA gene:
Search GeneIP for patents involving NACA
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NACA gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NACA | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NACA | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NACA | | | OriGene Protein Over-expression Lysate for NACA | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NACA | | OriGene 3'-UTR Clone for NACA | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NACA | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NACA | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NACA | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NACA | | OriGene Custom Protein Services for NACA | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NACA | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NACA | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NACA | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NACA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NACA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NACA |
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| | | | Search Tocris compounds for NACA |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NACA |
|  |  |  | | | | Search ThermoFisher Antibodies for NACA |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NACA |
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