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NAA50 Gene

protein-coding   GIFtS: 52
GCID: GC03M113437

N(Alpha)-Acetyltransferase 50, NatE Catalytic Subunit

(Previous names: Mak3 homolog (S. cerevisiae), N-acetyltransferase 13, N-acetyltransferase...)
(Previous symbols: MAK3, NAT13)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
N(Alpha)-Acetyltransferase 50, NatE Catalytic Subunit1 2     N-Acetyltransferase San Homolog2 3
NAT131 2 3 5     SAN2 5
MAK31 2 3     Mak3 Homolog (S. Cerevisiae)1
NAT52 3 5     NAT13P2
N-Acetyltransferase 13 (GCN5-Related)1 2     NAT5P2
N-Acetyltransferase 131 3     Mak3 Homolog2
NatE Catalytic Subunit2 3     N-Alpha-Acetyltransferase 502
hNAT52 3     N-Alpha-Acetyltransferase 50, NatE Catalytic Subunit2
hSAN2 3     Separation Anxiety2
N-Acetyltransferase 52 3     EC 2.3.1.-3

External Ids:    HGNC: 295331   Entrez Gene: 802182   Ensembl: ENSG000001215797   OMIM: 6108345   UniProtKB: Q9GZZ13   

Export aliases for NAA50 gene to outside databases

Previous GC identifer: GC03M110812


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NAA50 Gene:
NAA50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit) is a protein-coding gene. GO annotations related to this gene include N-acetyltransferase activity.

UniProtKB/Swiss-Prot: NAA50_HUMAN, Q9GZZ1
Function: Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal)
acetyltransferase activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NAA50
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAA50 promoter sequence
   Search Chromatin IP Primers for NAA50

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NAA50


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.2   Ensembl cytogenetic band:  3q13.2   HGNC cytogenetic band: 3q13.31

NAA50 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAA50 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M113437:  view genomic region     (about GC identifiers)

Start:
113,435,307 bp from pter      End:
113,465,147 bp from pter
Size:
29,841 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NAA50_HUMAN, Q9GZZ1 (See protein sequence)
Recommended Name: N-alpha-acetyltransferase 50  
Size: 169 amino acids; 19398 Da
Subunit: Interacts with NAA35 (By similarity). Interacts with NAA15 and NAA11
3 PDB 3D structures from and Proteopedia for NAA50:
2OB0 (3D)        2PSW (3D)        3TFY (3D)    
Secondary accessions: D3DN74 Q68DQ1
Alternative splicing: 2 isoforms:  Q9GZZ1-1   Q9GZZ1-2   (No experimental confirmation available. Contains a N6-acetyllysine at position 34)

Explore the universe of human proteins at neXtProt for NAA50: NX_Q9GZZ1

Explore proteomics data for NAA50 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys34, Lys37, Lys126, Lys152
  • Modification sites at PhosphoSitePlus

  • See NAA50 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079422.1  
    ENSEMBL proteins: 
     ENSP00000240922   ENSP00000417110   ENSP00000417488   ENSP00000418490   ENSP00000418473  
     ENSP00000418323   ENSP00000417837   ENSP00000419729  

    NAA50 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    NAA: N(alpha)-acetyltransferase subunits

    2 InterPro protein domains:
     IPR000182 GNAT_dom
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry Q9GZZ1

    ProtoNet protein and cluster: Q9GZZ1

    UniProtKB/Swiss-Prot: NAA50_HUMAN, Q9GZZ1
    Similarity: Belongs to the acetyltransferase family. GNAT subfamily
    Similarity: Contains 1 N-acetyltransferase domain


    Find genes that share domains with NAA50           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAA50_HUMAN, Q9GZZ1
    Function: Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal)
    acetyltransferase activity

         Enzyme Number (IUBMB): EC 2.3.1.-1

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004596peptide alpha-N-acetyltransferase activity IDA17502424
    GO:0005515protein binding IPI16507339
    GO:0008080N-acetyltransferase activity ----
    GO:0010485H4 histone acetyltransferase activity IDA19744929
    GO:0052858peptidyl-lysine N-acetyltransferase activity IDA19744929
         
    Find genes that share ontologies with NAA50           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NAA50
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAA50
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NAA50

    miRNA
    Products:
        
    miRTarBase miRNAs that target NAA50:
    hsa-mir-155-5p (MIRT020825), hsa-mir-1229-3p (MIRT036324), hsa-mir-192-5p (MIRT026586), hsa-mir-26b-5p (MIRT029581), hsa-let-7b-5p (MIRT032326), hsa-mir-215-5p (MIRT024728)

    Block miRNA regulation of human, mouse, rat NAA50 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NAA50 (see all 148):
    hsa-miR-411* hsa-miR-579 hsa-miR-3938 hsa-miR-376b hsa-miR-128 hsa-miR-938 hsa-miR-3074-3p hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidNAA50 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat NAA50

    Gene Editing
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NAA50 (NM_025146)
    Sino Biological Human cDNA Clone for NAA50
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAA50
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAA50
    Addgene plasmids for NAA50 

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for NAA50 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAA50


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NAA50_HUMAN, Q9GZZ1: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA16507339
    GO:0031415colocalizes with NatA complex IDA16507339
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with NAA50           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NAA50 About    
    See pathways by source

    SuperPathContained pathways About
    1Biological oxidations
    metapathway biotransformation0.42


    1 BioSystems Pathway for NAA50
        metapathway biotransformation



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NAA50
    Interactions:

        Search GeneGlobe Interaction Network for NAA50

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NAA50 (Q9GZZ13 ENSP000002409224) via UniProtKB, MINT, STRING, and/or I2D (see all 67)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EIF1BO607393, ENSP000002329054I2D: score=1 STRING: ENSP00000232905
    CYP3A4P086843I2D: score=5 
    DDA1Q9BW613I2D: score=1 
    TRAF6Q9Y4K33I2D: score=1 
    UBA5Q9GZZ93I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006474N-terminal protein amino acid acetylation TAS16507339
    GO:0043967histone H4 acetylation IDA19744929
    GO:0071962mitotic sister chromatid cohesion, centromeric IDA17502424

    Find genes that share ontologies with NAA50           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NAA50



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NAA50 gene: 
    NM_025146.2  

    Unigene Cluster for NAA50:

    N(alpha)-acetyltransferase 50, NatE catalytic subunit
    Hs.372378  [show with all ESTs]
    Unigene Representative Sequence: NM_025146
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000240922(uc010hqm.2 uc011bij.2 uc003ean.2) ENST00000477813
    ENST00000497525 ENST00000497255 ENST00000493454 ENST00000481432 ENST00000493900
    ENST00000478020 ENST00000467022
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NAA50 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NAA50 (see all 148):
    hsa-miR-411* hsa-miR-579 hsa-miR-3938 hsa-miR-376b hsa-miR-128 hsa-miR-938 hsa-miR-3074-3p hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidNAA50 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NAA50
    Predesigned siRNA for gene silencing in human, mouse, rat NAA50
    Clone
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    OriGene clones in human, mouse for NAA50 (see all 7)
    OriGene ORF clones in mouse, rat for NAA50
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NAA50 (NM_025146)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAA50
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAA50
    Addgene plasmids for NAA50 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NAA50
    OriGene qSTAR qPCR primer pairs in human, mouse for NAA50
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAA50
      QuantiTect SYBR Green Assays in human, mouse, rat NAA50
      QuantiFast Probe-based Assays in human, mouse, rat NAA50

    Additional mRNA sequence: 

    AK022540.1 AK023090.1 AK023256.1 AK296456.1 AK307184.1 AK311403.1 AK315876.1 BC012731.2 
    CR749314.1 

    Selected DOTS entries (see all 25):

    DT.80100959  DT.120919577  DT.101983516  DT.100663051  DT.120919499  DT.104062  DT.100829009  DT.120919388 
    DT.91935021  DT.120919412  DT.120919362  DT.120919454  DT.104061  DT.87011728  DT.100641093  DT.120919378 
    DT.121312617  DT.120919439  DT.120919450  DT.120919486  DT.92394648  DT.92449061  DT.95329606  DT.95329607 

    Selected AceView cDNA sequences (see all 521):

    R68785 AW575466 BU161167 AI251844 BQ921324 CB139805 AA382450 BG257648 
    AW850934 CN481312 BQ962896 AW770843 BQ102248 BG779257 AA827879 AW572694 
    AU117029 BQ223689 BU180835 CD370557 AI918660 BQ102515 BQ004272 BP360089 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NAA50    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c
    SP1:                          -                                       
    SP2:                          -                                       
    SP3:                    -     -                                       
    SP4:                                                                  


    ECgene alternative splicing isoforms for NAA50

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NAA50 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTGGTGGT
    NAA50 Expression
    About this image


    NAA50 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    NAA50 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NAA50 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.372378
        Custom PCR Arrays for NAA50
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat NAA50
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAA50

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NAA50 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Naa501 , 5 N(alpha)-acetyltransferase 50, NatE catalytic subunit1, 5 92.26(n)1
    98.81(a)1
      16 (28.47 cM)5
    721171  NM_028108.31  NP_082384.11 
     441398305 
    chicken
    (Gallus gallus)
    Aves NAA501 N(alpha)-acetyltransferase 50, NatE catalytic subunit 89.47(n)
    99.34(a)
      418319  NM_001030778.1  NP_001025949.1 
    lizard
    (Anolis carolinensis)
    Reptilia NAA506
    N(alpha)-acetyltransferase 50, NatE catalytic subu...
    97(a)
    1 ↔ 1
    GL343473.1(380771-398953)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.243702 Xenopus laevis transcribed sequence with strong similarity more 83.67(n)    CF284154.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb01d062 Transcribed sequence with strong similarity to protein more 83.48(n)    CF999251.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta san6
    separation anxiety
    64(a)
    1 ↔ 1
    2R(7248213-7249376)
    worm
    (Caenorhabditis elegans)
    Secernentea F40F4.76
    F54E7.96
    Protein F54E7.9 (F54E7.9) mRNA, complete cds
    31(a)
    30(a)
    many → 1
    many → 1
    X(3243887-3245980) WBGene00018238
    III(5676747-5677892) WBGene00018831
    barley
    (Hordeum vulgare)
    Liliopsida AJ435171.12   -- 70.14(n)    AJ435171.1 


    ENSEMBL Gene Tree for NAA50 (if available)
    TreeFam Gene Tree for NAA50 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NAA50 gene

    Find genes that share paralogs with NAA50           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for NAA50
    PGOHUM00000242270 PGOHUM00000237911


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NAA50 (see all 522)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs752887641,2
    C,F--113434818(+) AACTTG/TTATCT 1 -- int11Minor allele frequency- T:0.03EA 120
    rs787710491,2
    C,F--113434820(+) CTTGTA/TTCTGT 1 -- int11Minor allele frequency- T:0.03EA 120
    rs1819072441,2
    --113434840(+) CCTTTC/TCCACT 1 -- int10--------
    rs1494672551,2
    --113435055(+) AGTCAC/TAGATA 1 -- int10--------
    rs1845394721,2
    --113435164(+) AGATCA/GTTTCT 1 -- int10--------
    rs1438599661,2
    --113435184(+) AAGTGA/CTAAGA 1 -- int10--------
    rs729526591,2
    C,F--113435474(+) ATAATC/TAGATG 1 -- ut313Minor allele frequency- T:0.10WA 122
    rs1890319161,2
    --113435507(+) CAACAC/TGTGCT 1 -- ut310--------
    rs1158570041,2
    C,F--113435579(+) CAAGTA/GAAACT 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs1814214441,2
    --113435784(+) TTCATA/TTTAAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NAA50 (113435307 - 113465147 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NAA50:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv519099CNV Loss19592680
    nsv829678CNV Loss17160897
    nsv877351CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610834    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for NAA50:
    Borderline personality disorder

    Find genes that share disorders with NAA50           About GenesLikeMe


    Export disorders for NAA50 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NAA50 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with NAA50)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates. (PubMed id 19660095)1, 2, 3 Polevoda B.... Sherman F. (BMC Proc. 2009)
    2. Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex. (PubMed id 16507339)1, 2, 3 Arnesen T....Lillehaug J.R. (Gene 2006)
    3. The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent manner. (PubMed id 17502424)1, 3 Hou F....Zou H. (J. Cell Biol. 2007)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
    7. Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. (PubMed id 23557624)1 Foyn H....Arnesen T. (ACS Chem. Biol. 2013)
    8. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    9. Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study. (PubMed id 22311970)1 Evjenth R.H....Lillehaug J.R. (J. Biol. Chem. 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80218 HGNC: 29533 AceView: MAK3 Ensembl:ENSG00000121579 euGenes: HUgn80218
    ECgene: NAA50 H-InvDB: NAA50

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NAA50 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NAA50 gene:
    Search GeneIP for patents involving NAA50

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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