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Aliases for NAA38 Gene

Aliases for NAA38 Gene

  • N(Alpha)-Acetyltransferase 38, NatC Auxiliary Subunit 2 3
  • Phosphonoformate Immuno-Associated Protein 2 3 4
  • LSM Domain-Containing Protein 1 3 4
  • LSM Domain Containing 1 2 3
  • PFAAP2 3 4
  • LSMD1 3 4
  • N-Alpha-Acetyltransferase 38, NatC Auxiliary Subunit 3
  • Regulated By Phosphonoformate 3
  • MAK31 4

External Ids for NAA38 Gene

Previous Symbols for NAA38 Gene

  • LSMD1

Summaries for NAA38 Gene

GeneCards Summary for NAA38 Gene

NAA38 (N(Alpha)-Acetyltransferase 38, NatC Auxiliary Subunit) is a Protein Coding gene. GO annotations related to this gene include U6 snRNA binding.

UniProtKB/Swiss-Prot for NAA38 Gene

  • Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAA38 Gene

Genomics for NAA38 Gene

Genomic Location for NAA38 Gene

Start:
7,856,685 bp from pter
End:
7,885,238 bp from pter
Size:
28,554 bases
Orientation:
Minus strand

Genomic View for NAA38 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NAA38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAA38 Gene

No data available for Regulatory Elements for NAA38 Gene

Proteins for NAA38 Gene

  • Protein details for NAA38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BRA0-LSMD1_HUMAN
    Recommended name:
    N-alpha-acetyltransferase 38, NatC auxiliary subunit
    Protein Accession:
    Q9BRA0
    Secondary Accessions:
    • Q8N4M0

    Protein attributes for NAA38 Gene

    Size:
    125 amino acids
    Molecular mass:
    13514 Da
    Quaternary structure:
    • Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

    Alternative splice isoforms for NAA38 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NAA38 Gene

Proteomics data for NAA38 Gene at MOPED

Post-translational modifications for NAA38 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NAA38 Gene

No data available for DME Specific Peptides for NAA38 Gene

Domains for NAA38 Gene

Gene Families for NAA38 Gene

HGNC:
  • NAA :N(alpha)-acetyltransferase subunits

UniProtKB/Swiss-Prot:

LSMD1_HUMAN
Family:
  • Belongs to the snRNP Sm proteins family.:
    • Q9BRA0
genes like me logo Genes that share domains with NAA38: view

Function for NAA38 Gene

Molecular function for NAA38 Gene

UniProtKB/Swiss-Prot Function: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.

Gene Ontology (GO) - Molecular Function for NAA38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with NAA38: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NAA38 Gene

Localization for NAA38 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NAA38 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NAA38 Gene COMPARTMENTS Subcellular localization image for NAA38 gene
Compartment Confidence
nucleus 5
cytosol 3
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for NAA38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA 19398576
GO:0005844 colocalizes_with polysome IDA 19398576
GO:0031417 NatC complex IDA 19398576
genes like me logo Genes that share ontologies with NAA38: view

Pathways for NAA38 Gene

SuperPathways for NAA38 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NAA38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043066 negative regulation of apoptotic process IMP 19398576
genes like me logo Genes that share ontologies with NAA38: view

No data available for Pathways by source for NAA38 Gene

Transcripts for NAA38 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for NAA38 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3
SP1: -
SP2:
SP3: -

Relevant External Links for NAA38 Gene

GeneLoc Exon Structure for
NAA38
ECgene alternative splicing isoforms for
NAA38

Expression for NAA38 Gene

mRNA expression in normal human tissues for NAA38 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NAA38 Gene

genes like me logo Genes that share expressions with NAA38: view

Orthologs for NAA38 Gene

This gene was present in the common ancestor of animals.

Orthologs for NAA38 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LSMD1 37
  • 98 (a)
OneToOne
NAA38 36
  • 99.42 (n)
  • 98.27 (a)
cow
(Bos Taurus)
Mammalia LSMD1 37
  • 77 (a)
OneToOne
NAA38 36
  • 88.69 (n)
  • 88.24 (a)
dog
(Canis familiaris)
Mammalia LSMD1 37
  • 40 (a)
OneToOne
NAA38 36
  • 87.67 (n)
  • 85.55 (a)
mouse
(Mus musculus)
Mammalia Lsmd1 16
Lsmd1 37
  • 76 (a)
OneToOne
Naa38 36
  • 83.33 (n)
  • 94 (a)
oppossum
(Monodelphis domestica)
Mammalia LSMD1 37
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Naa38 36
  • 83.67 (n)
  • 94 (a)
chicken
(Gallus gallus)
Aves LSMD1 36
  • 76.07 (n)
  • 75.64 (a)
LSMD1 37
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia LSMD1 37
  • 66 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.6876 36
tropical clawed frog
(Silurana tropicalis)
Amphibia naa38 36
  • 71.87 (n)
  • 75 (a)
Str.17236 36
zebrafish
(Danio rerio)
Actinopterygii lsmd1 37
  • 64 (a)
OneToOne
naa38 36
  • 66.27 (n)
  • 78.57 (a)
wufj33f12 36
fruit fly
(Drosophila melanogaster)
Insecta CG31950 37
  • 33 (a)
OneToOne
Species with no ortholog for NAA38:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NAA38 Gene

ENSEMBL:
Gene Tree for NAA38 (if available)
TreeFam:
Gene Tree for NAA38 (if available)

Paralogs for NAA38 Gene

Selected SIMAP similar genes for NAA38 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with NAA38: view

No data available for Paralogs for NAA38 Gene

Variants for NAA38 Gene

Structural Variations from Database of Genomic Variants (DGV) for NAA38 Gene

Variant ID Type Subtype PubMed ID
nsv7405 OTHER Inversion 18451855
nsv889088 CNV Gain 21882294
nsv5920 CNV Insertion 18451855

Relevant External Links for NAA38 Gene

HapMap Linkage Disequilibrium report
NAA38

No data available for Sequence variations from dbSNP and Humsavar for NAA38 Gene

Disorders for NAA38 Gene

Relevant External Links for NAA38

Genetic Association Database (GAD)
NAA38
genes like me logo Genes that share disorders with NAA38: view

No data available for UniProtKB/Swiss-Prot for NAA38 Gene

Publications for NAA38 Gene

  1. Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization. (PMID: 19398576) Starheim K.K. … Arnesen T. (Mol. Cell. Biol. 2009) 2 3 4
  2. Embryonic growth-associated protein is one subunit of a novel N- terminal acetyltransferase complex essential for embryonic vascular development. (PMID: 16484612) Wenzlau J.M. … Weiser-Evans M.C.M. (Circ. Res. 2006) 2 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for NAA38 Gene

Sources for NAA38 Gene

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