Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAA15 Gene

protein-coding   GIFtS: 49
GCID: GC04P140222

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

(Previous name: NMDA receptor regulated 1 )
(Previous symbol: NARG1)
 Explore 20 diseases affiliated with
NAA15 via our new
 Human Malady Compendium 
Biological research products
for NAA15
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
N(Alpha)-Acetyltransferase 15, NatA Auxiliary Subunit1 2     NMDA Receptor-Regulated Protein 12 3
NARG11 2 3     FLJ133401
NATH1 2 3     Ga192
TBDN1001 2 3     N-Alpha-Acetyltransferase 15, NatA Auxiliary Subunit2
NMDA Receptor Regulated 11 2     Transcriptional Coactivator Tubedown-1002
Gastric Cancer Antigen Ga192 3     Tubedown-11
Protein Tubedown-12 3     GA193
N-Terminal Acetyltransferase2 3     Tbdn1003

External Ids:    HGNC: 307821   Entrez Gene: 801552   Ensembl: ENSG000001641347   OMIM: 6080005   UniProtKB: Q9BXJ93   

Export aliases for NAA15 gene to outside databases

Previous GC identifer: GC04P135952


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NAA15:
This gene encodes a protein of unknown function. However, similarity to proteins in yeast and other species suggests
that this protein may be an N-acetyltransferase. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
Function: The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for
vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult
ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin
promoter

Gene Wiki entry for NAA15 (NARG1)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NAA15
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAA15 promoter sequence
   Search SABiosciences Chromatin IP Primers for NAA15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAA15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q31.1   Ensembl cytogenetic band:  4q31.1   HGNC cytogenetic band: 4q31.1

NAA15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAA15 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P140222:  view genomic region     (about GC identifiers)

Start:
140,222,609 bp from pter      End:
140,341,187 bp from pter
Size:
118,579 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9 (See protein sequence)
Recommended Name: N-alpha-acetyltransferase 15, NatA auxiliary subunit  
Size: 866 amino acids; 101272 Da
Subunit: Interacts with NAA10, XRCC6, NAA50, XRCC5 and HYPK. Associates with HYPK when in a complex with NAA10
Subcellular location: Cytoplasm. Nucleus. Note=Mainly cytoplasmic, nuclear in some cases. Present in the free cytosolic
and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes
Sequence caution: Sequence=AAH39818.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A
sequence;
Secondary accessions: D3DNY6 Q52LG9 Q8IWH4 Q8NEV2 Q9H8P6
Alternative splicing: 2 isoforms:  Q9BXJ9-1   Q9BXJ9-4   

Explore the universe of human proteins at neXtProt for NAA15: NX_Q9BXJ9

Post-translational modifications:

  • Cleaved by caspases during apoptosis, resulting in a stable 35 kDa fragment1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BXJ9

  • NAA15 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_476516.1  
    ENSEMBL proteins: 
     ENSP00000296543   ENSP00000381920   ENSP00000421839  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for NAA15 
    GenScript Custom Purified and Recombinant Proteins Services for NAA15
    Novus Biologicals NAA15 Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12145306
    GO:0005667transcription factor complex IDA12145306
    GO:0005737cytoplasm IDA--


    NAA15 for ontologies           About GeneDecksing



    NAA15 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NAA15 
    GenScript Custom Superior Antibodies Services for NAA15
    Novus Biologicals NAA15 Antibodies
    Search for Antibodies for NAA15 at Abcam  
    Browse Antibodies at Uscn
    Search ThermoFisher Antibodies for NAA15

    Assay Products for NAA15: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NAA15
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NAA15 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011990 TPR-like_helical
     IPR013105 TPR_2
     IPR013026 TPR-contain_dom
     IPR021183 NatA_aux_su
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9BXJ9

    ProtoNet protein and cluster: Q9BXJ9

    1 Blocks protein family: IPB002197 FIS bacterial regulatory protein HTH signature

    UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
    Similarity: Contains 8 TPR repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
    Function: The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for
    vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult
    ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin
    promoter

    miRNA
    Products:
        
    miRTarBase miRNAs that target NAA15:
    hsa-mir-124 (MIRT004101), hsa-mir-16 (MIRT005271)

    OriGene 3'-UTR Clone: NAA15
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAA15
    8/138 QIAGEN miScript miRNA Assays for microRNAs that regulate NAA15 (see all 138):
    hsa-miR-128 hsa-miR-3653 hsa-miR-92b hsa-miR-509-3-5p hsa-miR-761 hsa-miR-374b* hsa-miR-130a* hsa-miR-32
    SwitchGear 3'UTR luciferase reporter plasmidNAA15 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAA15 (see all 4)
    OriGene shRNA RFP: NAA15
    OriGene siRNA: NAA15
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAA15

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NAA15

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAA15 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAA15
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NAA15 (NM_057175)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAA15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAA15 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NAA15
    Search LifeMap BioReagents cell lines for NAA15

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAA15

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16507339
    GO:0008080N-acetyltransferase activity IEA--
    GO:0016407contributes to acetyltransferase activity IDA15496142
    GO:0043022contributes to ribosome binding IDA15496142


    NAA15 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for NAA15:
     Increased G1 DNA content  Synthetic lethal with Ras 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAA15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/29 Interacting proteins for NAA15 (Q9BXJ93 ENSP000002965434) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NAA10P412273, ENSP000004177634I2D: score=4 STRING: ENSP00000417763
    UBA5Q9GZZ93, ENSP000003485654I2D: score=2 STRING: ENSP00000348565
    XRCC6P129563, ENSP000003522574I2D: score=2 STRING: ENSP00000352257
    RPL26P612543, ENSP000002938424I2D: score=1 STRING: ENSP00000293842
    TNIKQ9UKE53, ENSP000003995114I2D: score=1 STRING: ENSP00000399511
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006474N-terminal protein amino acid acetylation IDA15496142
    GO:0030154cell differentiation IEA--
    GO:0045893positive regulation of transcription, DNA-dependent IDA12145306


    NAA15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NAA15 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAA15
    1 Novoseek chemical compound relationship for NAA15 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    n-atc 89.6 1 15911569 (1)

    Search CenterWatch for drugs/clinical trials and news about NAA15 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NAA15 gene: 
    NM_057175.3  

    Unigene Cluster for NAA15:

    N(alpha)-acetyltransferase 15, NatA auxiliary subunit
    Hs.555985  [show with all ESTs]
    Unigene Representative Sequence: NM_057175
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296543(uc003ihu.1) ENST00000398947 ENST00000482087 ENST00000480277
    ENST00000468029 ENST00000496716 ENST00000485905 ENST00000515576

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: NAA15
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAA15
    8/138 QIAGEN miScript miRNA Assays for microRNAs that regulate NAA15 (see all 138):
    hsa-miR-128 hsa-miR-3653 hsa-miR-92b hsa-miR-509-3-5p hsa-miR-761 hsa-miR-374b* hsa-miR-130a* hsa-miR-32
    SwitchGear 3'UTR luciferase reporter plasmidNAA15 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAA15 (see all 4)
    OriGene shRNA RFP: NAA15
    OriGene siRNA: NAA15
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAA15
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAA15 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAA15
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NAA15 (NM_057175)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAA15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAA15 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAA15
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAA15
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAA15
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAA15

    Additional cDNA sequence: 

    AF327722.1 AJ314788.1 AK001595.1 AK023387.1 AK023402.1 AK091308.1 AK304417.1 AK314626.1 
    AY039242.1 AY112670.1 BC032642.1 BC039818.1 BC093928.1 BC104806.1 

    9 DOTS entries:

    DT.100647925  DT.100783125  DT.436409  DT.97847843  DT.99939452  DT.206919  DT.86851419  DT.121255691 
    DT.92005232 

    24/148 AceView cDNA sequences (see all 148):

    BM456794 AW294949 CK570340 CA418377 BX111747 AA907375 AA039428 AA845552 
    BM463359 CR614926 BC039818 AY112670 AI804279 NM_057175 AU130763 NM_025085 
    CA418241 AJ314788 AA707217 AL556909 BM044197 AI744486 CA429026 AU134337 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for NAA15 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c ^ 17 ^ 18 ^ 19a · 19b ^ 20a ·
    SP1:                    -     -                                                                                                                                 
    SP2:                    -     -                                                                                   -                                             
    SP3:                    -                                                                                                                                       
    SP4:                          -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 20b ^ 21 ^ 22a · 22b ^ 23
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:  -                           


    ECgene alternative splicing isoforms for NAA15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAA15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTGACAAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NAA15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAA15

    SOURCE GeneReport for Unigene cluster: Hs.555985

    UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
    Tissue specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus
    callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas,
    mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric
    cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in
    abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy

        SABiosciences Custom PCR Arrays for NAA15
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAA15
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAA15
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAA15
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAA15
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAA15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NAA15 gene from 9/31 species (see all 31)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Naa151 , 5 N(alpha)-acetyltransferase 15, NatA auxiliary subunit1, 5 93.1(n)1
    98.5(a)1
      3 (22.47 cM)5
    748381  NM_053089.31  NP_444319.31 
     514160165 
    chicken
    (Gallus gallus)
    Aves NAA151 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 85.83(n)
    96.1(a)
      422440  XM_420407.3  XP_420407.3 
    lizard
    (Anolis carolinensis)
    Reptilia NAA156
    --
    95(a)
    1 ↔ 1
    5(120272288-120306520)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.42002 Xenopus laevis putative N-terminal acetyltransferase more 80.29(n)    AF247679.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.153802 Danio rerio, Similar to transcriptional coactivator more 75.45(n)    AY391464.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nat11 CG12202-PA 53.61(n)
    54.94(a)
      32934  NM_133156.1  NP_573384.1 
    worm
    (Caenorhabditis elegans)
    Secernentea hpo-291 Protein HPO-29 52.38(n)
    44.1(a)
      175189  NM_064779.3  NP_497180.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons EMB27536
    tetratricopeptide repeat-containing protein
    39(a)
    1 → many
    1(30227485-30234985)
    rice
    (Oryza sativa)
    Liliopsida --
    tetratricopeptide repeat domain containing protein...
    39(a)
    1 → many
    1(24533783-24545651)


    ENSEMBL Gene Tree for NAA15 (if available)
    TreeFam Gene Tree for NAA15 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NAA15 gene
    NAA162  
    10 SIMAP similar genes for NAA15 using alignment to 2 protein entries:     NAA15_HUMAN (see all proteins):
    NARG1    NAA16    NARG1L    PAM16    L3MBTL2    ABCG5
    RHBDD3    ADCY7    SYNE1    LOC100506127

    NAA15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for NAA15
         2 CNVs: 37872 92421
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NAA15
    DNA2.0 Custom Variant and Variant Library Synthesis for NAA15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NAA15 for disorders           About GeneDecksing

    OMIM gene information: 608000    OMIM disorders: --

    20 diseases for NAA15:    About MalaCards
    estrogen-receptor negative breast cancer    gastric cancer    proliferative diabetic retinopathy    corpus callosum
    diabetic retinopathy    papillary thyroid carcinoma    herpes simplex    burkitt's lymphoma
    retinopathy of prematurity    thyroid carcinoma    thyroiditis    papilloma
    breast cancer    carcinoma    colorectal cancer    retinitis
    tuberculosis    malaria    neuronitis    mycobacterium tuberculosis

    2 Novoseek disease relationships for NAA15 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    thyroid papillary carcinoma 57.6 5 12140756 (2), 16279846 (2), 18991565 (1)
    tumors 0 3 12140756 (2), 16279846 (1)


    Export disorders for NAA15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAA15 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with NAA15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NATH, a novel gene overexpressed in papillary thyroid carcinomas. (PubMed id 12140756)1, 2, 3, 9 Fluge O.... Lillehaug J.R. (2002)
    2. A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates. (PubMed id 19660095)1, 2, 3 Polevoda B.... Sherman F. (2009)
    3. Identification and characterization of the human ARD1-NATH protein acetyltransferase complex. (PubMed id 15496142)1, 2, 9 Arnesen T....Lillehaug J.R. (2005)
    4. Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. (PubMed id 12145306)1, 2, 9 Willis D.M.... Towler D.A. (2002)
    5. A novel Xenopus acetyltransferase with a dynamic expression in early development. (PubMed id 11478804)1, 3, 9 Choi S.C....Han J.K. (2001)
    6. The chaperone-like protein HYPK acts together with Na tA in cotranslational N-terminal acetylation and prevention of Huntingtin aggre gation. (PubMed id 20154145)1, 2 Arnesen T....Anderson D. (2010)
    7. Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex. (PubMed id 16507339)1, 2 Arnesen T....Lillehaug J.R. (2006)
    8. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80155 HGNC: 30782 AceView: TBDN100 Ensembl:ENSG00000164134 euGenes: HUgn80155
    ECgene: NAA15 H-InvDB: NAA15

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAA15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NAA15 gene:
    Search GeneIP for patents involving NAA15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for NAA15  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAA15   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAA15  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for NAA15   OriGene 3'-UTR Clone for NAA15  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAA15   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAA15  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NAA15   OriGene Custom Protein Services for NAA15  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NAA15
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NAA15
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAA15
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAA15
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAA15
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAA15
     GenScript Custom Purified and Recombinant Proteins Services for NAA15 GenScript cDNA clones with any tag delivered in your preferred vector for NAA15
     GenScript Custom Assay Services for NAA15 GenScript Custom Superior Antibodies Services for NAA15
     GenScript Custom overexpressing Cell Line Services for NAA15 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for NAA15
     Search Chromatin IP Primers for NAA15
     RT2 qPCR Primer Assay in human, mouse, rat NAA15
     Search GNC Networks for NAA15
     SABiosciences Custom PCR Arrays for NAA15
     Search Tocris compounds for NAA15
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NAA15 antibodies
     NAA15 proteins
     Search for Antibodies for NAA15 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NAA15
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn
     Search LifeMap BioReagents cell lines for NAA15
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAA15
     SwitchGear 3'UTR luciferase reporter plasmids for NAA15
     SwitchGear Promoter luciferase reporter plasmids for NAA15
     Search ThermoFisher Antibodies for NAA15
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAA15
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NAA15 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4