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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAA15 Gene

protein-coding   GIFtS: 50
GCID: GC04P140222

N(Alpha)-Acetyltransferase 15, NatA Auxiliary Subunit

(Previous name: NMDA receptor regulated 1)
(Previous symbol: NARG1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
N(Alpha)-Acetyltransferase 15, NatA Auxiliary Subunit1 2     NMDA Receptor-Regulated Protein 12 3
NARG11 2 3     Ga192
NMDA Receptor Regulated 11 2     N-Alpha-Acetyltransferase 15, NatA Auxiliary Subunit2
Gastric Cancer Antigen Ga192 3     Transcriptional Coactivator Tubedown-1002
Protein Tubedown-12 3     tubedown-12
NATH2 3     GA193
TBDN1002 3     Tbdn1003
N-Terminal Acetyltransferase2 3     

External Ids:    HGNC: 307821   Entrez Gene: 801552   Ensembl: ENSG000001641347   OMIM: 6080005   UniProtKB: Q9BXJ93   

Export aliases for NAA15 gene to outside databases

Previous GC identifer: GC04P135952


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NAA15 Gene:
This gene encodes a protein of unknown function. However, similarity to proteins in yeast and other species
suggests that this protein may be an N-acetyltransferase. (provided by RefSeq, Jul 2008)

GeneCards Summary for NAA15 Gene: 
NAA15 (N(alpha)-acetyltransferase 15, NatA auxiliary subunit) is a protein-coding gene. Diseases associated with NAA15 include estrogen-receptor negative breast cancer, and gastric cancer. GO annotations related to this gene include acetyltransferase activity and ribosome binding. An important paralog of this gene is NAA16.

UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
Function: The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for
vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in
adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the
osteocalcin promoter

Gene Wiki entry for NAA15 (NARG1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NAA15
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAA15 promoter sequence
   Search SABiosciences Chromatin IP Primers for NAA15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAA15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q31.1   Ensembl cytogenetic band:  4q31.1   HGNC cytogenetic band: 4q31.1

NAA15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAA15 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P140222:  view genomic region     (about GC identifiers)

Start:
140,222,609 bp from pter      End:
140,341,187 bp from pter
Size:
118,579 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9 (See protein sequence)
Recommended Name: N-alpha-acetyltransferase 15, NatA auxiliary subunit  
Size: 866 amino acids; 101272 Da
Subunit: Interacts with NAA10, XRCC6, NAA50, XRCC5 and HYPK. Associates with HYPK when in a complex with NAA10
Subcellular location: Cytoplasm. Nucleus. Note=Mainly cytoplasmic, nuclear in some cases. Present in the free
cytosolic and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes
Sequence caution: Sequence=AAH39818.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: D3DNY6 Q52LG9 Q8IWH4 Q8NEV2 Q9H8P6
Alternative splicing: 2 isoforms:  Q9BXJ9-1   Q9BXJ9-4   

Explore the universe of human proteins at neXtProt for NAA15: NX_Q9BXJ9

Explore proteomics data for NAA15 at MOPED 

Post-translational modifications:

  • UniProtKB: Cleaved by caspases during apoptosis, resulting in a stable 35 kDa fragment
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BXJ9

  • NAA15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NAA15 Protein Expression
    REFSEQ proteins: NP_476516.1  
    ENSEMBL proteins: 
     ENSP00000296543   ENSP00000381920   ENSP00000421839  

    Human Recombinant Protein Products for NAA15: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12140756
    GO:0005667transcription factor complex IDA12145306
    GO:0005737cytoplasm IDA--

    NAA15 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NAA: N(alpha)-acetyltransferase subunits

    5 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR013105 TPR_2
     IPR013026 TPR-contain_dom
     IPR021183 NatA_aux_su
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9BXJ9

    ProtoNet protein and cluster: Q9BXJ9

    1 Blocks protein domain: IPB002197 FIS bacterial regulatory protein HTH signature

    UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
    Similarity: Contains 8 TPR repeats


    NAA15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAA15_HUMAN, Q9BXJ9
    Function: The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for
    vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in
    adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the
    osteocalcin promoter

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12145306
    GO:0008080N-acetyltransferase activity IEA--
    GO:0016407contributes to acetyltransferase activity IDA15496142
    GO:0043022contributes to ribosome binding IDA15496142
         
    NAA15 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NAA15:
     Increased G1 DNA content  Synthetic lethal with Ras 

    Animal Models:
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    8/138 QIAGEN miScript miRNA Assays for microRNAs that regulate NAA15 (see all 138):
    hsa-miR-128 hsa-miR-3653 hsa-miR-92b hsa-miR-509-3-5p hsa-miR-761 hsa-miR-374b* hsa-miR-130a* hsa-miR-32
    SwitchGear 3'UTR luciferase reporter plasmidNAA15 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAA15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/29 Interacting proteins for NAA15 (Q9BXJ93 ENSP000002965434) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NAA10P412273, ENSP000004177634I2D: score=4 STRING: ENSP00000417763
    UBA5Q9GZZ93, ENSP000003485654I2D: score=2 STRING: ENSP00000348565
    XRCC6P129563, ENSP000003522574I2D: score=2 STRING: ENSP00000352257
    RPL26P612543, ENSP000002938424I2D: score=1 STRING: ENSP00000293842
    TNIKQ9UKE53, ENSP000003995114I2D: score=1 STRING: ENSP00000399511
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006474N-terminal protein amino acid acetylation IDA15496142
    GO:0030154cell differentiation IEA--
    GO:0045893positive regulation of transcription, DNA-dependent IDA12145306

    NAA15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NAA15 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAA15

    1 Novoseek inferred chemical compound relationship for NAA15 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    n-atc 89.6 1 15911569 (1)

    Search CenterWatch for drugs/clinical trials and news about NAA15

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NAA15 gene: 
    NM_057175.3  

    Unigene Cluster for NAA15:

    N(alpha)-acetyltransferase 15, NatA auxiliary subunit
    Hs.745047  [show with all ESTs]
    Unigene Representative Sequence: NM_057175
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296543(uc003ihu.1) ENST00000398947 ENST00000482087 ENST00000480277
    ENST00000468029 ENST00000496716 ENST00000485905 ENST00000515576
    miRNA
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    hsa-miR-128 hsa-miR-3653 hsa-miR-92b hsa-miR-509-3-5p hsa-miR-761 hsa-miR-374b* hsa-miR-130a* hsa-miR-32
    SwitchGear 3'UTR luciferase reporter plasmidNAA15 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAA15

    Additional mRNA sequence: 

    AF327722.1 AJ314788.1 AK001595.1 AK023387.1 AK023402.1 AK091308.1 AK304417.1 AK314626.1 
    AY039242.1 AY112670.1 BC032642.1 BC039818.1 BC093928.1 BC104806.1 

    9 DOTS entries:

    DT.100647925  DT.100783125  DT.436409  DT.97847843  DT.99939452  DT.206919  DT.86851419  DT.121255691 
    DT.92005232 

    24/148 AceView cDNA sequences (see all 148):

    BX116461 BX647018 CA429026 AU119807 AK001595 BQ214565 BQ778193 BM044197 
    BU622204 AI804279 CK570340 AA845552 BM724518 AA761423 AL556909 NM_025085 
    CA418377 BX111747 BM463359 BP871471 BM834812 AA039352 AI744486 AA707217 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for NAA15 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c ^ 17 ^ 18 ^ 19a · 19b ^ 20a ·
    SP1:                    -     -                                                                                                                                 
    SP2:                    -     -                                                                                   -                                             
    SP3:                    -                                                                                                                                       
    SP4:                          -                                                                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 20b ^ 21 ^ 22a · 22b ^ 23
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:  -                           


    ECgene alternative splicing isoforms for NAA15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAA15 expression in normal human tissues (normalized intensities)      NAA15 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGACAAAG
    NAA15 Expression
    About this image


    NAA15 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Skeletal Muscle (Muscoskeletal System)
             deltoid muscle   

    See NAA15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAA15

    SOURCE GeneReport for Unigene cluster: Hs.745047

    UniProtKB/Swiss-Prot: NAA15_HUMAN, Q9BXJ9
    Tissue specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain
    (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver,
    pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract.
    Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi).
    Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic
    retinopathy

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAA15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NAA15 gene from 8/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Naa151 , 5 N(alpha)-acetyltransferase 15, NatA auxiliary subunit1, 5 93.1(n)1
    98.5(a)1
      3 (22.47 cM)5
    748381  NM_053089.31  NP_444319.31 
     514160165 
    chicken
    (Gallus gallus)
    Aves NAA151 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 85.83(n)
    96.1(a)
      422440  XM_420407.3  XP_420407.3 
    lizard
    (Anolis carolinensis)
    Reptilia NAA156
    Uncharacterized protein
    95(a)
    1 ↔ 1
    5(120269656-120307473)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.42002 Xenopus laevis putative N-terminal acetyltransferase more 80.29(n)    AF247679.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.153802 Danio rerio, Similar to transcriptional coactivator more 75.45(n)    AY391464.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nat11 CG12202-PA 53.61(n)
    54.94(a)
      32934  NM_133156.1  NP_573384.1 
    worm
    (Caenorhabditis elegans)
    Secernentea hpo-291 Protein HPO-29 52.38(n)
    44.1(a)
      175189  NM_064779.3  NP_497180.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NAT16
    Subunit of the N-terminal acetyltransferase NatA (...
    28(a)
    1 → many
    IV(378874-381438)


    ENSEMBL Gene Tree for NAA15 (if available)
    TreeFam Gene Tree for NAA15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NAA15 gene
    NAA162  
    10 SIMAP similar genes for NAA15 using alignment to 2 protein entries:     NAA15_HUMAN (see all proteins):
    NARG1    NAA16    NARG1L    PAM16    L3MBTL2    ABCG5
    RHBDD3    ADCY7    SYNE1    LOC100506127

    NAA15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1578 SNPs in NAA15 are shown (see all 1578)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1817145331,2
    --140225827(+) TTTTAC/TCTATG 1 -- int10--------
    rs802119471,2
    F--140225884(+) GCAGCA/GTTATC 1 -- int10--------
    rs1499726051,2
    --140225910(+) ACCACC/TACAAT 1 -- int10--------
    rs1856882091,2
    --140225925(+) CTACAC/GAACAA 1 -- int10--------
    rs1442286781,2
    --140225951(+) AGTACC/TCCCCT 1 -- int10--------
    rs1893641621,2
    --140226010(+) ATCCCC/TTCTCG 1 -- int10--------
    rs786472451,2
    C,F--140226205(+) AGTAGG/CGGGGA 1 -- int13Minor allele frequency- C:0.26CSA WA 121
    rs1158786651,2
    C,F--140226221(+) ACAGGG/TCTACT 1 -- int11Minor allele frequency- T:0.03NA 120
    rs1400473271,2
    C--140226377(+) CTGTAA/CGTTTA 1 -- int10--------
    rs1436706621,2
    --140226592(+) CTTTTA/GAGATT 1 -- int10--------

    HapMap Linkage Disequilibrium report for NAA15 (140222609 - 140341187 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for NAA15:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2728426CNV Deletion23290073
    dgv977e199CNV Deletion23128226
    nsv4529CNV Insertion18451855
    nsv830084CNV Loss17160897
    nsv822748CNV Loss20364138
    nsv514254CNV Loss21397061
    nsv880160CNV Gain21882294
    nsv442922CNV CNV18776908

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608000    OMIM disorders: --

    17 diseases for NAA15:    About MalaCards
    estrogen-receptor negative breast cancer    gastric cancer    retinopathy of prematurity    proliferative diabetic retinopathy
    papillary thyroid carcinoma    diabetic retinopathy    papillary carcinoma    papilloma
    burkitt's lymphoma    herpes simplex    thyroiditis    tuberculosis
    retinitis    colorectal cancer    breast cancer    endotheliitis
    neuronitis


    NAA15 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for NAA15 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    thyroid papillary carcinoma 57.6 5 12140756 (2), 16279846 (2), 18991565 (1)
    tumors 0 3 12140756 (2), 16279846 (1)


    Export disorders for NAA15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAA15 gene, integrated from 9 sources (see all 60):
    (articles sorted by number of sources associating them with NAA15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NATH, a novel gene overexpressed in papillary thyroid carcinomas. (PubMed id 12140756)1, 2, 3, 9 Fluge O.... Lillehaug J.R. (2002)
    2. A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates. (PubMed id 19660095)1, 2, 3 Polevoda B.... Sherman F. (2009)
    3. Identification and characterization of the human ARD1-NATH protein acetyltransferase complex. (PubMed id 15496142)1, 2, 9 Arnesen T....Lillehaug J.R. (2005)
    4. Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. (PubMed id 12145306)1, 2, 9 Willis D.M.... Towler D.A. (2002)
    5. A novel Xenopus acetyltransferase with a dynamic expression in early development. (PubMed id 11478804)1, 3, 9 Choi S.C....Han J.K. (2001)
    6. The chaperone-like protein HYPK acts together with Na tA in cotranslational N-terminal acetylation and prevention of Huntingtin aggre gation. (PubMed id 20154145)1, 2 Arnesen T....Anderson D. (2010)
    7. Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex. (PubMed id 16507339)1, 2 Arnesen T....Lillehaug J.R. (2006)
    8. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80155 HGNC: 30782 AceView: TBDN100 Ensembl:ENSG00000164134 euGenes: HUgn80155
    ECgene: NAA15 H-InvDB: NAA15

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAA15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NAA15 gene:
    Search GeneIP for patents involving NAA15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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