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N6AMT1 Gene

protein-coding   GIFtS: 55
GCID: GC21M030244

N-6 Adenine-Specific DNA Methyltransferase 1 (Putative)

(Previous names: chromosome 21 open reading frame 127, HemK methyltransferase...)
(Previous symbols: C21orf127, HEMK2)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
N-6 Adenine-Specific DNA Methyltransferase 1 (Putative)1 2     MTQ22
C21orf1271 2 3     N6-DNA-methyltransferase2
HEMK21 2 3     N6AMT2
HemK Methyltransferase Family Member 21 2     m.HsaHemK2P2
N(6)-Adenine-Specific DNA Methyltransferase 12 3     EC 2.1.1.-3
Chromosome 21 Open Reading Frame 1271     M.HsaHemK2P3

External Ids:    HGNC: 160211   Entrez Gene: 291042   Ensembl: ENSG000001562397   OMIM: 6145535   UniProtKB: Q9Y5N53   

Export aliases for N6AMT1 gene to outside databases

Previous GC identifers: GC21M026827 GC21M029166 GC21M015649


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for N6AMT1 Gene:
This gene encodes protein methyltransferase. The encoded enzyme may be involved in the methylation of release
factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite
monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternate splicing results in multiple transcript
variants. A pseudogene of this gene is found on chromosome 11. (provided by RefSeq, Mar 2012)

GeneCards Summary for N6AMT1 Gene:
N6AMT1 (N-6 adenine-specific DNA methyltransferase 1 (putative)) is a protein-coding gene. GO annotations related to this gene include protein methyltransferase activity and nucleic acid binding.

UniProtKB/Swiss-Prot: HEMK2_HUMAN, Q9Y5N5
Function: Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl
L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently
methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of
monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000021.8  NC_018932.2  NT_011512.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the N6AMT1 gene promoter:
         E2F-4   E2F-3a   E2F-5   NCX/Ncx   Nkx2-2   E2F-2   YY1   E2F   Ik-2   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidN6AMT1 promoter sequence
   Search Chromatin IP Primers for N6AMT1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat N6AMT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q21.3   Ensembl cytogenetic band:  21q21.3   HGNC cytogenetic band: 21q21.3

N6AMT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
N6AMT1 gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21M030244:  view genomic region     (about GC identifiers)

Start:
30,244,513 bp from pter      End:
30,257,693 bp from pter
Size:
13,181 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: HEMK2_HUMAN, Q9Y5N5 (See protein sequence)
Recommended Name: HemK methyltransferase family member 2  
Size: 214 amino acids; 22900 Da
Subunit: Heterodimer with TRMT112
Caution: Was originally (Ref.1) proposed to be a DNA methyltransferase, but was then shown to be a protein
methyltransferase (PubMed:18539146)
Secondary accessions: Q96F73
Alternative splicing: 2 isoforms:  Q9Y5N5-1   Q9Y5N5-2   

Explore the universe of human proteins at neXtProt for N6AMT1: NX_Q9Y5N5

Explore proteomics data for N6AMT1 at MOPED


See N6AMT1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_037372.3  NP_877426.3  

ENSEMBL proteins: 
 ENSP00000303584   ENSP00000286764   ENSP00000436490  

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR004557 PrmC_related
 IPR002052 DNA_methylase_N6_adenine_CS

Graphical View of Domain Structure for InterPro Entry Q9Y5N5

ProtoNet protein and cluster: Q9Y5N5

1 Blocks protein domain: IPB002052 N-6 Adenine-specific DNA methylase

UniProtKB/Swiss-Prot: HEMK2_HUMAN, Q9Y5N5
Similarity: Belongs to the eukaryotic/archaeal PrmC-related family


Find genes that share domains with N6AMT1           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: HEMK2_HUMAN, Q9Y5N5
Function: Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl
L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently
methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of
monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid

     Enzyme Number (IUBMB): EC 2.1.1.-1

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding IEA--
GO:0005515protein binding IPI18539146
GO:0008168methyltransferase activity ----
GO:0008276protein methyltransferase activity IDA18539146
     
Find genes that share ontologies with N6AMT1           About GenesLikeMe


Phenotypes:
     3 GenomeRNAi human phenotypes for N6AMT1:
 Cell cycle / mitosis defect  Increased cell number in G1, s  Synthetic lethal with c-Myc af 

     3 MGI mutant phenotypes (inferred from 1 allele(MGI details for N6amt1):
 embryogenesis  growth/size/body  mortality/aging 

Find genes that share phenotypes with N6AMT1           About GenesLikeMe

Animal Models:
     MGI mouse knock-out N6amt1tm1Gxu for N6AMT1

   genOway: Develop your customized and physiologically relevant rodent model for N6AMT1

miRNA
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miRTarBase miRNAs that target N6AMT1:
hsa-mir-99a-5p (MIRT048642), hsa-mir-26b-5p (MIRT029107)

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2 qRT-PCR Assays for microRNAs that regulate N6AMT1:
hsa-miR-4328 hsa-miR-513a-3p
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol3
nucleus2
peroxisome1
plasma membrane1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005737cytoplasm ----
GO:0043234protein complex IDA18539146

Find genes that share ontologies with N6AMT1           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for N6AMT1
Interactions:

    Search GeneGlobe Interaction Network for N6AMT1

STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

Selected Interacting proteins for N6AMT1 (Q9Y5N52, 3 ENSP000003035844) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
InteractantInteraction Details
GeneCardExternal ID(s)
TRMT112Q9UI302, 3, ENSP000003094334MINT-6571489 I2D: score=1 STRING: ENSP00000309433
RBBP5Q152913, ENSP000002645154I2D: score=6 STRING: ENSP00000264515
MTRF1LQ9UGC73, ENSP000003562024I2D: score=1 STRING: ENSP00000356202
ETF1P624953, ENSP000003537414I2D: score=1 STRING: ENSP00000353741
KIAA1456Q9P2723I2D: score=2 
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006479protein methylation IDA18539146
GO:0030307positive regulation of cell growth IDA18539146

Find genes that share ontologies with N6AMT1           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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  Browse compounds at ApexBio 

Browse Tocris compounds for N6AMT1 (HEMK2)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for N6AMT1 gene (2 alternative transcripts): 
NM_013240.4  NM_182749.3  

Unigene Cluster for N6AMT1:

N-6 adenine-specific DNA methyltransferase 1 (putative)
Hs.163846  [show with all ESTs]
Unigene Representative Sequence: AK021678
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000303775(uc002ymo.1) ENST00000351429(uc002ymp.1) ENST00000460212(uc002ymq.1)

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hsa-miR-4328 hsa-miR-513a-3p
SwitchGear 3'UTR luciferase reporter plasmidN6AMT1 3' UTR sequence
Inhib. RNA
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  QuantiFast Probe-based Assays in human, mouse, rat N6AMT1

Additional mRNA sequence: 

AF139682.1 AK021678.1 AK225515.1 AK314100.1 BC011554.1 NR_047510.1 

4 DOTS entries:

DT.91651052  DT.101976162  DT.100815348  DT.100832676 

Selected AceView cDNA sequences (see all 70):

CR616062 CR612892 CR620576 BE348272 BF026677 Z40121 BG477556 BX328055 
AL558133 AI684642 AK092128 AK021678 BC011554 F07022 AF139682 BI520047 
BU625644 AI523341 BM312393 BX506362 CA843746 BQ710426 AU118636 AW136986 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for N6AMT1    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1:                                                            
SP2:                                -                           
SP3:                                -                           


ECgene alternative splicing isoforms for N6AMT1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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N6AMT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AAGGACCCCT
N6AMT1 Expression
About this image


N6AMT1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 6) fully expand
 
 Brain (Nervous System)    fully expand to see all 4 entries
         Cerebral Cortex
 
 Trophoblast (Extraembryonic Tissues)
         Trophoblast Cells Trophoblast
 
 Ovary (Reproductive System)
         Oviduct
 
 Testis (Reproductive System)
         Leydig Cells Testis Interstitium
 
 Liver (Hepatobiliary System)
         Hepatocytes Liver Lobule
N6AMT1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

N6AMT1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.163846

UniProtKB/Swiss-Prot: HEMK2_HUMAN, Q9Y5N5
Tissue specificity: Widely expressed, with highest expression in parathyroid and pituitary glands, followed by
adrenal gland and kidney, and lowest expression in leukocytes and mammary gland

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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for N6AMT1 gene from Selected species (see all 19)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia N6amt11 , 5 N-6 adenine-specific DNA methyltransferase 1 (putative)1, 5 84.11(n)1
86.92(a)1
  16 (49.52 cM)5
677681  NM_026366.21  NP_080642.11 
 873541855 
chicken
(Gallus gallus)
Aves N6AMT11 N-6 adenine-specific DNA methyltransferase 1 (putative) 71.36(n)
71.83(a)
  418481  NM_001278078.1  NP_001265007.1 
lizard
(Anolis carolinensis)
Reptilia N6AMT16
N-6 adenine-specific DNA methyltransferase 1 (puta...
58(a)
1 ↔ 1
3(146650466-146657416)
African clawed frog
(Xenopus laevis)
Amphibia Xl.212862 Xenopus laevis transcribed sequence with moderate similarity more 75.23(n)    BX853748.1 
zebrafish
(Danio rerio)
Actinopterygii n6amt11 N-6 adenine-specific DNA methyltransferase 1 (putative) 59.97(n)
62.68(a)
  436775  NM_001002502.1  NP_001002502.1 
fruit fly
(Drosophila melanogaster)
Insecta snapin3
CG99601
synaptic vesicle exocytosis3
CG99601
39(a)3
49.1(n)1
41.87(a)1
  23A3
37719661  NM_001032050.21  NP_001027221.11 
worm
(Caenorhabditis elegans)
Secernentea C33C12.93
CELE_C33C12.91
CELE_C33C12.91 47(a)3
50.09(n)1
48.13(a)1
  II(2187216-2189751)3
1735751  NM_061808.31  NP_494209.21 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MTQ2(YDR140W)4 S-adenosylmethionine-dependent methyltransferase of more   --   4(734138-734803) 851718  NP_010424.1 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G134401 AT3G13440 48.56(n)
41.62(a)
  820545  NM_112189.3  NP_187952.1 
rice
(Oryza sativa)
Liliopsida Os03g08242001 Os03g0824200 50.6(n)
44.04(a)
  4334624  NM_001058284.1  NP_001051749.1 


ENSEMBL Gene Tree for N6AMT1 (if available)
TreeFam Gene Tree for N6AMT1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for N6AMT1 gene
1 SIMAP similar gene for N6AMT1 using alignment to 1 protein entry:     HEMK2_HUMAN:
HEMK2

Find genes that share paralogs with N6AMT1           About GenesLikeMe


1 Pseudogenes.org Pseudogene for N6AMT1
PGOHUM00000242428


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for N6AMT1 (see all 452)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 21 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs81340051,2
C,F,A,H--30244170(+) tcattG/Aactca 1 -- ds500123Minor allele frequency- A:0.33NS EA NA WA CSA 2353
rs27389551,2
C,H--30244213(+) ccctaT/Cgtctc 1 -- ds500113Minor allele frequency- C:0.00NA WA CSA EA 378
rs350280161,2
C--30244258(+) GACAC-/AAGAGA 1 -- ds50012Minor allele frequency- A:0.25NA CSA 4
rs622222001,2
C,F--30244282(+) GCCCAT/CCCTAA 1 -- ds50013Minor allele frequency- C:0.16WA NA EA 358
rs622222011,2
C,F--30244311(+) TAACTT/GGATTA 1 -- ds50013Minor allele frequency- G:0.16WA NA EA 358
rs1852547661,2
--30244381(+) ATTTTA/GTTGGG 1 -- ds50010--------
rs1492210681,2
--30244386(+) GTTGGA/GGGGAC 1 -- ds50010--------
rs790016071,2
C--30244449(+) GCTCCA/TTAGTT 1 -- ds50010--------
rs1885220901,2
--30244461(+) AGTTAA/CATTTG 1 -- ds50010--------
rs1481999561,2
C--30244497(+) AGGCAC/TGCGTA 1 -- ds50010--------

HapMap Linkage Disequilibrium report for N6AMT1 (30244513 - 30257693 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for N6AMT1:    About this table    
Variant IDTypeSubtypePubMed ID
nsv9862CNV Gain18304495
dgv1371e1CNV Complex17122850

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 614553    OMIM disorders: --


Find genes that share disorders with N6AMT1           About GenesLikeMe

Genetic Association Database (GAD): N6AMT1
Human Genome Epidemiology (HuGE) Navigator: N6AMT1 (1 document)

Export disorders for N6AMT1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for N6AMT1 gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with N6AMT1)
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  1. HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1. (PubMed id 18539146)1, 2, 9 Figaro S.... Heurgue-Hamard V. (FEBS Lett. 2008)
  2. Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity. (PubMed id 21193388)1, 2 Ren X.... Zhang L. (Environ. Health Perspect. 2011)
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  4. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M.... Yaspo M.-L. (Nature 2000)
  5. N-6-adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms and arsenic methylation in Andean women. (PubMed id 23665909)1 Harari F....Broberg K. (Environ. Health Perspect. 2013)
  6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29104 HGNC: 16021 AceView: C21orf127 Ensembl:ENSG00000156239 euGenes: HUgn29104
ECgene: N6AMT1 H-InvDB: N6AMT1

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for N6AMT1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for N6AMT1 gene:
Search GeneIP for patents involving N6AMT1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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