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Aliases & Descriptions for N4BP2L2
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases 92M18.3 2 CG005 1 , 2 , 3 CG016 2 FLJ36195 2 FLJ41089 2 FLJ43077 2 OTTHUMP00000018230 2 OTTHUMP00000042409 2 OTTHUMP00000042420 2 PFAAP5 1 , 2 , 3
Descriptions 92M18.3 (novel protein) 2 NEDD4 binding protein 2-like 2 2 Phosphonoformate immuno-associated protein 5 2 , 3 protein from BCRA2 region 2
Search outside databases for aliases for N4BP2L2 gene
Summaries for N4BP2L2 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Location for N4BP2L2
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 13q13.1 Ensembl cytogenetic band: 13q13.1 HGNC cytogenetic band: 13q13.1 N4BP2L2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 13 GeneLoc Exon Structure
GeneLoc location for GC13M031891:
(about GC identifiers )
Start:
31,891,545 bp from pter
End:
32,010,936 bp from pter
Size:
119,392 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000013.9 NT_024524.13 Proteins for N4BP2L2
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: N42L2_HUMAN, Q92802 (See
protein sequence )Recommended Name: NEDD4-binding protein 2-like 2 Size : 583 amino acids; 67459 Da
Secondary accessions : A3KME8Alternative splicing : 2 isoforms : Q92802-1 Q92802-2
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
View phosphorylation sites using PhosphoSite 2 (PFAAP5)
REFSEQ proteins (2 alternative transcripts):
NP_055702.1 NP_149102.3 ENSEMBL proteins: ENSP00000267068 ENSP00000369464 ENSP00000350104 ENSP00000382328 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 1 Gene Ontology (GO) cellular component term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005575 cellular_component
ND --
About this table Antibodies for N4BP2L2: Assays for N4BP2L2:
Protein
Domains/ Families for N4BP2L2(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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ProtoNet protein and cluster: Q92802
Gene Function for N4BP2L2
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_033111 Applied Biosystems Silencer ® siRNAs for N4BP2L2 Sigma-Aldrich siRNA for N4BP2L2 Sigma-Aldrich shRNA for N4BP2L2 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_014887                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_014887                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_014887  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_033111 1 Gene Ontology (GO) molecular function term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0003674 molecular_function
ND --
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Pathways & Interactions for N4BP2L2
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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1 Interacting protein for N4BP2L2 (ENSP00000350104 3 ) via UniProtKB, MINT, and/or STRING About this table 1 Gene Ontology (GO) biological process term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0008150 biological_process
ND --
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Drugs & Compounds for N4BP2L2 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Transcripts for N4BP2L2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
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OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_033111 Sigma-Aldrich siRNA for N4BP2L2 Sigma-Aldrich shRNA for N4BP2L2 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_014887 NM_033111
REFSEQ mRNAs for N4BP2L2 gene (2 alternative transcripts): NM_014887.2 NM_033111.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_014887 NM_033111
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_014887                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_014887                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_014887  
Additional cDNA sequence: AF530063.1 AK093514.1 AK123084.1 AK298546.1 AK310280.1 AK312924.1 AL049783.1 AL049802.1 BC010643.1 BC131631.1 BT007172.1 CR596312.1 CR601845.1 U50529.1 U50532.1 U50535.1 Z36834.1
24/45 DOTS entries (see all 45
): DT.317482 DT.91754565 DT.412749 DT.92454943 DT.100797278 DT.120793871 DT.100777575 DT.95325227 DT.100797284 DT.109140 DT.92454928 DT.100797290 DT.100797280 DT.100797279 DT.120793931 DT.95368042 DT.100797275 DT.92454938 DT.97847541 DT.120793822 DT.100655678 DT.91745197 DT.92420379 DT.100737250
24/449 AceView cDNA sequences (see all 449
):AW236098 BE645120 CD722084 AU117279 BQ267843 AA890530 AK093514 CB240991 BE502838 AL049788 BP379646 AI338989 AL596913 BM543104 AW009076 BM670744 NM_052818 BM456347 BX483989 BC010643 AI536840 CA840895 BM667255 AA488718
Unigene Cluster for N4BP2L2: NEDD4 binding protein 2-like 2 Hs.507680 [show with all ESTs ] Unigene Representative Sequence: NM_014887 GeneLoc Exon Structure 5/14 Alternative Splicing Database (ASD) splice patterns (SP) for N4BP2L2 (see all 14
) ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ SP1 :                                                     SP2 :                                             -   -     -   SP3 :                         -     -   -                       SP4 :                       -   -     -   -       -   -   -   -   -   -   -   -   SP5 :                                     -   -   -   -   -   -     -  
ExUns: 14 ^ 15 ^ 16a · 16b · 16c · 16d · 16e ^ 17 ^ 18 ^ 19a · 19b SP1 :                       SP2 :   -                     SP3 :                       SP4 : -   -                     SP5 : -   -                    
About this scheme ECgene alternative splicing isoforms for N4BP2L2 4 Ensembl transcripts including schematic representations : ENST00000267068
ENST00000380121
ENST00000357505
ENST00000399396
Expression for N4BP2L2
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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N4BP2L2 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for N4BP2L2 1 / 2
14 probe-sets matching N4BP2L2 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GTGTGTCTCGSOURCE GeneReport for Unigene cluster: Hs.507680
Orthologs for N4BP2L2
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for N4BP2L2 gene from 4 species
About this table Species with no ortholog for N4BP2L2 ENSEMBL Gene Tree for N4BP2L2 Paralogs for N4BP2L2 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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SNPs/Variants for N4BP2L2 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for N4BP2L2 (up to first 250kb)
Disorders & Mutations for N4BP2L2
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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Medical News for N4BP2L2 (Possibly Related Articles in
Doctor's Guide )
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Publications for N4BP2L2 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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8 PubMed articles for N4BP2L2 gene :
Search for N4BP2L2
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Genome Databases showing N4BP2L2
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing N4BP2L2
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Specialized Databases showing N4BP2L2 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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