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Aliases for N4BP2L1 Gene

Aliases for N4BP2L1 Gene

  • NEDD4 Binding Protein 2-Like 1 2 3
  • Hypothetical Gene CG018 2 3
  • CG018 3
  • CG081 4

External Ids for N4BP2L1 Gene

Previous GeneCards Identifiers for N4BP2L1 Gene

  • GC13M031872
  • GC13M032974
  • GC13M013786

Summaries for N4BP2L1 Gene

GeneCards Summary for N4BP2L1 Gene

N4BP2L1 (NEDD4 Binding Protein 2-Like 1) is a Protein Coding gene. GO annotations related to this gene include kinase activity. An important paralog of this gene is N4BP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for N4BP2L1 Gene

Genomics for N4BP2L1 Gene

Regulatory Elements for N4BP2L1 Gene

Genomic Location for N4BP2L1 Gene

32,400,723 bp from pter
32,429,614 bp from pter
28,892 bases
Minus strand

Genomic View for N4BP2L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for N4BP2L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for N4BP2L1 Gene

Proteins for N4BP2L1 Gene

  • Protein details for N4BP2L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    NEDD4-binding protein 2-like 1
    Protein Accession:
    Secondary Accessions:
    • A4QN21
    • Q5TBK0

    Protein attributes for N4BP2L1 Gene

    243 amino acids
    Molecular mass:
    28981 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for N4BP2L1 Gene


neXtProt entry for N4BP2L1 Gene

Proteomics data for N4BP2L1 Gene at MOPED

Post-translational modifications for N4BP2L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for N4BP2L1 Gene

Domains & Families for N4BP2L1 Gene

Protein Domains for N4BP2L1 Gene


Suggested Antigen Peptide Sequences for N4BP2L1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with N4BP2L1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for N4BP2L1 Gene

Function for N4BP2L1 Gene

Phenotypes for N4BP2L1 Gene

genes like me logo Genes that share phenotypes with N4BP2L1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for N4BP2L1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for N4BP2L1 Gene

Localization for N4BP2L1 Gene

Subcellular locations from

Jensen Localization Image for N4BP2L1 Gene COMPARTMENTS Subcellular localization image for N4BP2L1 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for N4BP2L1 Gene

Pathways & Interactions for N4BP2L1 Gene

SuperPathways for N4BP2L1 Gene

No Data Available

Interacting Proteins for N4BP2L1 Gene

Gene Ontology (GO) - Biological Process for N4BP2L1 Gene


No data available for Pathways by source and SIGNOR curated interactions for N4BP2L1 Gene

Drugs & Compounds for N4BP2L1 Gene

No Compound Related Data Available

Transcripts for N4BP2L1 Gene

Unigene Clusters for N4BP2L1 Gene

NEDD4 binding protein 2-like 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for N4BP2L1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for N4BP2L1 Gene

No ASD Table

Relevant External Links for N4BP2L1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for N4BP2L1 Gene

mRNA expression in normal human tissues for N4BP2L1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for N4BP2L1 Gene

This gene is overexpressed in Liver (24.7), CD8 Tcells (20.4), Blymphocyte (15.6), and NK cells (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for N4BP2L1 Gene

SOURCE GeneReport for Unigene cluster for N4BP2L1 Gene Hs.732118

genes like me logo Genes that share expression patterns with N4BP2L1: view

Protein tissue co-expression partners for N4BP2L1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for N4BP2L1 Gene

Orthologs for N4BP2L1 Gene

This gene was present in the common ancestor of animals.

Orthologs for N4BP2L1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia N4BP2L1 35
  • 89.81 (n)
  • 90.67 (a)
N4BP2L1 36
  • 82 (a)
(Mus musculus)
Mammalia N4bp2l1 35
  • 83.61 (n)
  • 81.93 (a)
N4bp2l1 16
N4bp2l1 36
  • 84 (a)
(Pan troglodytes)
Mammalia N4BP2L1 35
  • 98.22 (n)
  • 96.71 (a)
N4BP2L1 36
  • 96 (a)
(Rattus norvegicus)
Mammalia N4bp2l1 35
  • 82.91 (n)
  • 81.51 (a)
(Bos Taurus)
Mammalia N4BP2L1 36
  • 75 (a)
(Monodelphis domestica)
Mammalia N4BP2L1 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia N4BP2L1 36
  • 7 (a)
(Gallus gallus)
Aves N4BP2L1 35
  • 73.48 (n)
  • 69.06 (a)
N4BP2L1 36
  • 58 (a)
(Anolis carolinensis)
Reptilia N4BP2L1 36
  • 59 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia n4bp2l1 35
  • 75 (n)
  • 72.37 (a)
(Danio rerio)
Actinopterygii N4BP2L1 36
  • 19 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7139 36
  • 7 (a)
Species with no ortholog for N4BP2L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for N4BP2L1 Gene

Gene Tree for N4BP2L1 (if available)
Gene Tree for N4BP2L1 (if available)

Paralogs for N4BP2L1 Gene

Paralogs for N4BP2L1 Gene

(3) SIMAP similar genes for N4BP2L1 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with N4BP2L1: view

Variants for N4BP2L1 Gene

Structural Variations from Database of Genomic Variants (DGV) for N4BP2L1 Gene

Variant ID Type Subtype PubMed ID
nsv832576 CNV Gain 17160897

Variation tolerance for N4BP2L1 Gene

Residual Variation Intolerance Score: 30.11% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.27; 6.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for N4BP2L1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for N4BP2L1 Gene

Disorders for N4BP2L1 Gene

Relevant External Links for N4BP2L1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with N4BP2L1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for N4BP2L1 Gene

Publications for N4BP2L1 Gene

  1. Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. (PMID: 8812419) Couch F.J. … Simard J. (Genomics 1996) 2 67
  2. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 67
  3. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. (PMID: 23535733) Garcia-Closas M. … Kraft P. (Nat. Genet. 2013) 67
  4. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 67
  5. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 67

Products for N4BP2L1 Gene

Sources for N4BP2L1 Gene

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