Aliases for MYT1L Gene
External Ids for MYT1L Gene
Previous GeneCards Identifiers for MYT1L Gene
This gene encodes a member of the zinc finger superfamily of transcription factors. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
GeneCards Summary for MYT1L Gene
MYT1L (Myelin Transcription Factor 1 Like) is a Protein Coding gene. Diseases associated with MYT1L include Mental Retardation, Autosomal Dominant 39 and Autism Spectrum Disorder. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MYT1.
UniProtKB/Swiss-Prot for MYT1L Gene
May function as a panneural transcription factor associated with neuronal differentiation. May play a role in the development of neurons and oligodendroglia in the CNS (By similarity).