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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MYSM1 Gene

protein-coding   GIFtS: 55
GCID: GC01M059120

Myb-Like, SWIRM And MPN Domains 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Myb-Like, SWIRM And MPN Domains 11 2     RP4-592A1.12
Myb-Like, SWIRM And MPN Domain-Containing Protein 12 3     Histone H2A Deubiquitinase MYSM12
2A-DUB2 3     EC 3.4.19.-3
2ADUB2 5     EC 3.1.2.158
KIAA19153 5     

External Ids:    HGNC: 294011   Entrez Gene: 1148032   Ensembl: ENSG000001626017   OMIM: 6121765   UniProtKB: Q5VVJ23   

Export aliases for MYSM1 gene to outside databases

Previous GC identifers: GC01M058833 GC01M058892 GC01M057235


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MYSM1 Gene: 
MYSM1 (Myb-like, SWIRM and MPN domains 1) is a protein-coding gene. Diseases associated with MYSM1 include bronchogenic carcinoma, and diabetic retinopathy. GO annotations related to this gene include chromatin binding and ubiquitin thiolesterase activity. An important paralog of this gene is MPND.

UniProtKB/Swiss-Prot: MYSM1_HUMAN, Q5VVJ2
Function: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for
epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates
monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the
phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the
initiation and elongation steps of androgen receptor (AR)-induced gene activation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYSM1 gene promoter:
         TBP   HNF-1A   FOXL1   MEF-2A   HNF-1   TFIID   FOXJ2 (long isoform)   aMEF-2   FOXJ2   TGIF   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MYSM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYSM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.1   Ensembl cytogenetic band:  1p32.1   HGNC cytogenetic band: 1p32.1

MYSM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYSM1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M059120:  view genomic region     (about GC identifiers)

Start:
59,120,411 bp from pter      End:
59,165,764 bp from pter
Size:
45,354 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MYSM1_HUMAN, Q5VVJ2 (See protein sequence)
Recommended Name: Histone H2A deubiquitinase MYSM1  
Size: 828 amino acids; 95032 Da
Subunit: Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and
KIF11/TRIP5. Binds histones
Subcellular location: Nucleus
Sequence caution: Sequence=BAB67808.1; Type=Erroneous initiation; Sequence=BAG54377.1; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for MYSM1:
2CU7 (3D)        2DCE (3D)    
Secondary accessions: A8KA54 B3KX65 Q68DD3 Q6AI53 Q7Z3G8 Q96PX3
Alternative splicing: 3 isoforms:  Q5VVJ2-1   Q5VVJ2-2   Q5VVJ2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MYSM1: NX_Q5VVJ2

Explore proteomics data for MYSM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VVJ2

  • 4/12 DME Specific Peptides for MYSM1 (Q5VVJ2) (see all 12)
     LTCLQKLL  DPFQLIPC  RLQSMRTR  IGAINFGCE 

    MYSM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MYSM1 Protein Expression
    REFSEQ proteins: NP_001078956.1  
    ENSEMBL proteins: 
     ENSP00000418734  

    Human Recombinant Protein Products for MYSM1: 
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    Novus Biologicals MYSM1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MYSM1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA18669648

    MYSM1 for ontologies           About GeneDecksing



    MYSM1 Antibody Products: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MYSM1 
    Cloud-Clone Corp. CLIAs for MYSM1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR000555 JAB1_Mov34_MPN_PAD1
     IPR017884 SANT_dom
     IPR001005 SANT/Myb
     IPR011991 WHTH_DNA-bd_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q5VVJ2

    ProtoNet protein and cluster: Q5VVJ2

    1 Blocks protein domain: IPB000555 Mov34 family

    UniProtKB/Swiss-Prot: MYSM1_HUMAN, Q5VVJ2
    Domain: Binds double-stranded DNA via the SANT domain. The SWIRM domain does not bind double-stranded DNA
    Similarity: Belongs to the peptidase M67A family. MYSM1 subfamily
    Similarity: Contains 1 MPN (JAB/Mov34) domain
    Similarity: Contains 1 SANT domain
    Similarity: Contains 1 SWIRM domain


    MYSM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MYSM1_HUMAN, Q5VVJ2
    Function: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for
    epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates
    monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the
    phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the
    initiation and elongation steps of androgen receptor (AR)-induced gene activation

         Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.-1

         Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0003713transcription coactivator activity IDA18669648
    GO:0004221ubiquitin thiolesterase activity IDA18669648
    GO:0004843ubiquitin-specific protease activity IDA18669648
         
    MYSM1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MYSM1:
     Lamellipodia cells 

         15 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mysm1):
     adipose tissue  behavior/neurological  cellular  craniofacial  growth/size 
     hematopoietic system  homeostasis/metabolism  immune system  integument  limbs/digits/tail 
     mortality/aging  other  pigmentation  skeleton  vision/eye 

    MYSM1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MYSM1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MYSM1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MYSM1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MYSM1 

    miRNA
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    hsa-miR-21* hsa-miR-323-3p hsa-miR-3685 hsa-miR-607 hsa-miR-429 hsa-miR-199a-3p hsa-miR-200a hsa-miR-128
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYSM1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MYSM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/34 Interacting proteins for MYSM1 (Q5VVJ23 ENSP000004187344) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSPA1AP081073, ENSP000003648024I2D: score=2 STRING: ENSP00000364802
    ENSG00000212866P081073I2D: score=2 
    ENSG00000215328P081073I2D: score=2 
    ENSG00000224501P081073I2D: score=2 
    ENSG00000231555P081073I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006508proteolysis IEA--
    GO:0016578histone deubiquitination IDA18669648
    GO:0045893positive regulation of transcription, DNA-dependent IDA18669648

    MYSM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MYSM1

    Search CenterWatch for drugs/clinical trials and news about MYSM1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MYSM1 gene: 
    NM_001085487.2  

    Unigene Cluster for MYSM1:

    Myb-like, SWIRM and MPN domains 1
    Hs.744921  [show with all ESTs]
    Unigene Representative Sequence: AB067502
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000472487(uc001cza.3 uc001czc.3 uc009wab.2 uc001czd.3)
    ENST00000493821 ENST00000401044 ENST00000481973 ENST00000466774 ENST00000483003
    ENST00000489282
    miRNA
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    8/58 QIAGEN miScript miRNA Assays for microRNAs that regulate MYSM1 (see all 58):
    hsa-miR-21* hsa-miR-323-3p hsa-miR-3685 hsa-miR-607 hsa-miR-429 hsa-miR-199a-3p hsa-miR-200a hsa-miR-128
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Browse for Gene Knock-down Tools from EMD Millipore
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    OriGene clones in human, mouse for MYSM1 (see all 9)
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    GenScript: all cDNA clones in your preferred vector: MYSM1 (NM_001085487)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYSM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYSM1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYSM1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYSM1

    Additional mRNA sequence: 

    AB067502.1 AK126835.1 AK292919.1 BC017579.1 BC037536.1 BX537912.1 BX648168.1 CR627323.1 
    CR749450.1 

    10 DOTS entries:

    DT.415163  DT.91998275  DT.100663053  DT.95225199  DT.40264891  DT.101967775  DT.100738895  DT.121358447 
    DT.95167412  DT.95167413 

    24/151 AceView cDNA sequences (see all 151):

    R12524 AI376858 CB163594 AW571573 BU952502 AA226746 Z42019 BM723744 
    AI655166 AA357512 BC017579 BM263185 AA290597 BX502513 AL135188 AV651910 
    CR627323 AA744868 BX116216 AL710088 AW968237 BM679945 AW673302 BX486864 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for MYSM1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b
    SP1:                                                                    -                                             
    SP2:                                                        -     -                                                   
    SP3:                                                                                                                  


    ECgene alternative splicing isoforms for MYSM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MYSM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGAAAATTC
    MYSM1 Expression
    About this image


    See MYSM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MYSM1

    SOURCE GeneReport for Unigene cluster: Hs.744921
        SABiosciences Expression via Pathway-Focused PCR Array including MYSM1: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYSM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MYSM1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mysm11 , 5 myb-like, SWIRM and MPN domains 11, 5 85.39(n)1
    80.29(a)1
      4 (43.34 cM)5
    3207131  NM_177239.21  NP_796213.21 
     949420405 
    chicken
    (Gallus gallus)
    Aves MYSM11 myb-like, SWIRM and MPN domains 1 73.8(n)
    74.75(a)
      424671  NM_001012927.1  NP_001012945.1 
    lizard
    (Anolis carolinensis)
    Reptilia MYSM16
    Uncharacterized protein
    69(a)
    1 ↔ 1
    5(716044-734853)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.30622 Xenopus laevis transcribed sequence with weak similarity more 76.77(n)    BX846683.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mysm11 Myb-like, SWIRM and MPN domains 1 58.66(n)
    57.87(a)
      561225  NM_001164029.1  NP_001157501.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG47516
    --
    6(a)
    1 → many
    2L(11130741-11136003)


    ENSEMBL Gene Tree for MYSM1 (if available)
    TreeFam Gene Tree for MYSM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MYSM1 gene
    MPND2  

    MYSM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1114 SNPs in MYSM1 are shown (see all 1114)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1422985231,2
    --59120013(+) CCAAAA/CCTCTC 1 -- ds50010--------
    rs45532231,2
    C,F,A--59120107(+) TTAGGC/TGGCTT 1 -- ds500113Minor allele frequency- T:0.35NA WA EA 516
    rs740790091,2
    C,F--59120152(+) CCAGAG/TAATTT 1 -- ds50012Minor allele frequency- T:0.14WA 120
    rs75197511,2
    C,F,A,H--59120184(+) CATTAC/TCCTGG 1 -- ds500111Minor allele frequency- T:0.24NS EA NA CSA WA 782
    rs1114712051,2
    C--59120262(+) CTTCTT/GGTGGG 1 -- ds50012Minor allele frequency- G:0.10WA 120
    rs1880686171,2
    --59120315(+) CTATAC/TAACAG 1 -- ds50010--------
    rs412876521,2
    --59120384(+) TATTGC/TTAATA 1 -- ds50010--------
    rs2328611,2
    C,F,O,A,H--59120399(-) GGATTC/ATTTCT 1 -- ds500116Minor allele frequency- A:0.37NA WA CSA EA 519
    rs2328601,2
    C,F,A,H--59120563(-) AGAATT/CATGAA 1 -- ut31 ese324Minor allele frequency- C:0.28MN NS EA NA WA CSA 2529
    rs153071,2
    C,F,O,H--59120579(-) AAATAT/CCTGCA 1 -- ut3115Minor allele frequency- C:0.13MN EA NS NA WA CSA 893

    HapMap Linkage Disequilibrium report for MYSM1 (59120411 - 59165764 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for MYSM1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv820181CNV Loss19587683
    dgv42n67CNV Gain20364138
    nsv819698CNV Gain19587683
    dgv43n67CNV Gain20364138
    dgv41n67CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612176    OMIM disorders: --

    2 diseases for MYSM1:    About MalaCards
    bronchogenic carcinoma    diabetic retinopathy

    1 disease from the University of Copenhagen DISEASES database for MYSM1:
    Bronchogenic carcinoma

    MYSM1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MYSM1
    Human Genome Epidemiology (HuGE) Navigator: MYSM1 (1 document)

    Export disorders for MYSM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MYSM1 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MYSM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural and functional differences of SWIRM domain subtypes. (PubMed id 17428495)1, 2, 3, 9 Yoneyama M.... Yokoyama S. (2007)
    2. A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. (PubMed id 17707232)1, 2, 3 Zhu P....Rosenfeld M.G. (2007)
    3. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2, 3 Nagase T....Ohara O. (2001)
    4. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)1, 2 Dephoure N.... Gygi S.P. (2008)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 114803 HGNC: 29401 AceView: KIAA1915 Ensembl:ENSG00000162601 euGenes: HUgn114803
    ECgene: MYSM1 H-InvDB: MYSM1

    (According to HUGE)
    About This Section
    HUGE: KIAA1915

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MYSM1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MYSM1 gene:
    Search GeneIP for patents involving MYSM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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