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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MYRIP Gene

protein-coding GIFtS: 55
GCID: GC03P039826

myosin VIIA and Rab interacting protein

Explore 3 diseases affiliated with
MYRIP via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Myosin VIIA And Rab Interacting Protein¹ ²		DKFZp586F1018¹
SLAC2C¹ ² ³ ⁵		MyRIP¹
SLAC2-C¹ ²		Rab Effector MyRIP²
Exophilin-8³		Slp Homologue Lacking C2 Domains²
Myosin-VIIa- And Rab-Interacting Protein² ³		Synaptotagmin-Like Protein Homologue Lacking C2 Domains-C²
Slp Homolog Lacking C2 Domains C² ³		Exophilin-8³
Synaptotagmin-Like Protein Lacking C2 Domains C² ³		SlaC2-C¹

External Ids:	HGNC: 19156¹	Entrez Gene: 25924²	Ensembl: ENSG00000170011⁷	OMIM: 611790⁵	UniProtKB: Q8NFW9³

Export aliases for MYRIP gene to outside databases

Previous GC identifers: GC03P039190 GC03P039084 GC03P039664 GC03P039811

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9

Function: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the

motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase

A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery,

thus facilitating exocytosis, including insulin release (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_022517.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MYRIP gene promoter:
AhR Max1 Tal-1 XBP-1 E47 Arnt CBF-B CBF-A c-Myc CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MYRIP promoter sequence

Search SABiosciences Chromatin IP Primers for MYRIP

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYRIP

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.1 Ensembl cytogenetic band: 3p22.1 HGNC cytogenetic band: 3p21.33

MYRIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYRIP gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P039826: view genomic region (about GC identifiers)

Start:	39,850,405 bp from pter	End:	40,301,812 bp from pter
Size:	451,408 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9 (See protein sequence)

Recommended Name: Rab effector MyRIP

Size: 859 amino acids; 95706 Da

Subunit: Binds MYO5A, MYO7A and F-actin (By similarity). Binds RAB27A that has been activated by GTP-binding via its

N-terminus. Interacts with PRKAR2A. Interacts with components of the exocyst complex, including EXOC3 and EXOC4 (By

similarity)

Subcellular location: Cytoplasm (By similarity). Cytoplasm, perinuclear region (By similarity). Cytoplasmic vesicle,

secretory vesicle (By similarity). Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal

microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments (By

similarity)

Secondary accessions: B3KWM3 B3KWW4 B7Z2H1 B7Z9V3 G3XAI8 Q32M41 Q569F7 Q8IUF5 Q9Y3V4

Alternative splicing: 5 isoforms: Q8NFW9-1 Q8NFW9-2 Q8NFW9-3 Q8NFW9-4 Q8NFW9-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MYRIP: NX_Q8NFW9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NFW9

MYRIP Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_056275.2

ENSEMBL proteins:

ENSP00000398665 ENSP00000301972 ENSP00000389323 ENSP00000400916 ENSP00000413392

ENSP00000379519 ENSP00000438297

Human Recombinant Protein Products for MYRIP:

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	Uscn Proteins for MYRIP

Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000145	exocyst	IEA	--
GO:0001750	photoreceptor outer segment	IEA	--
GO:0005622	intracellular	--	--
GO:0015629	actin cytoskeleton	IEA	--
GO:0030133	transport vesicle	IEA	--

MYRIP for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for MYRIP

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MYRIP for domains About GeneDecksing

4 InterPro domains/families:

IPR006788 Myrip/Melanophilin

IPR013083 Znf_RING/FYVE/PHD

IPR011011 Znf_FYVE_PHD

IPR010911 Rab-bd_domain

Graphical View of Domain Structure for InterPro Entry Q8NFW9

ProtoNet protein and cluster: Q8NFW9

1 Blocks protein family: IPB000306 Zn-finger

UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9

Similarity: Contains 1 FYVE-type zinc finger

Similarity: Contains 1 RabBD (Rab-binding) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MYRIP_HUMAN, Q8NFW9

Function: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the

motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase

A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery,

thus facilitating exocytosis, including insulin release (By similarity)

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--
GO:0005515	protein binding	IPI	17827149
GO:0008270	zinc ion binding	NAS	11964381
GO:0017022	myosin binding	--	--
GO:0017137	Rab GTPase binding	IEA	--

MYRIP for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MYRIP

miRNA Products:		OriGene 3'-UTR Clone: MYRIP Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYRIP
		8/62 QIAGEN miScript miRNA Assays for microRNAs that regulate MYRIP (see all 62):
		hsa-miR-194* hsa-miR-579 hsa-let-7d hsa-miR-15a hsa-miR-200a hsa-miR-650 hsa-miR-449a hsa-miR-570

		SwitchGear 3'UTR luciferase reporter plasmid: MYRIP 3' UTR sequence

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYRIP (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYRIP OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYRIP

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

1.00

1 BioSystems Pathway for MYRIP

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for MYRIP

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/8 Interacting proteins for MYRIP (Q8NFW9^{2, 3} ENSP00000301972⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PIK3R1	P27986²^,³, ENSP00000274335⁴	MINT-8112123 I2D: score=3 STRING: ENSP00000274335
MYO7A	Q13402³, ENSP00000386331⁴	I2D: score=1 STRING: ENSP00000386331
RAB27A	P51159³, ENSP00000337761⁴	I2D: score=3 STRING: ENSP00000337761
NCK1	P16333³, ENSP00000288986⁴	I2D: score=2 STRING: ENSP00000288986
GRB2	P62993³, ENSP00000339007⁴	I2D: score=2 STRING: ENSP00000339007

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006886	intracellular protein transport	IEA	--
GO:0032024	positive regulation of insulin secretion	ISS	--

MYRIP for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MYRIP

1 HMDB Compound for MYRIP About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

Search CenterWatch for drugs/clinical trials and news about MYRIP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MYRIP gene:

NM_015460.2

Unigene Cluster for MYRIP:

Myosin VIIA and Rab interacting protein

Hs.594535 [show with all ESTs]

Unigene Representative Sequence: BC092512

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000444716 ENST00000302541(uc003cka.3 uc010hhu.3 uc010hhv.3 uc010hhw.3 uc011ayz.2)

ENST00000425621 ENST00000458441 ENST00000458292 ENST00000475082(uc010hhx.1)

ENST00000459828 ENST00000482033 ENST00000396217 ENST00000539167

miRNA Products:		OriGene 3'-UTR Clone: MYRIP Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYRIP
		8/62 QIAGEN miScript miRNA Assays for microRNAs that regulate MYRIP (see all 62):
		hsa-miR-194* hsa-miR-579 hsa-let-7d hsa-miR-15a hsa-miR-200a hsa-miR-650 hsa-miR-449a hsa-miR-570

		SwitchGear 3'UTR luciferase reporter plasmid: MYRIP 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: MYRIP (NM_015460)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYRIP
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYRIP

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYRIP
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYRIP

Additional cDNA sequence:

AB083783.1 AF396687.1 AK125334.1 AK126013.1 AK294714.1 AK310972.1 AK312412.1 AK316068.1

AL050090.1 BC092512.1 BC109311.1 BC109312.1

6 DOTS entries:

DT.411498 DT.99954773 DT.120871429 DT.439321 DT.40246508 DT.75104804

24/51 AceView cDNA sequences (see all 51):

AA323164 AI827924 AW594282 AA974678 AA195295 AW665105 AA258345 AB083783

F01507 AA579870 Z45990 BF478223 AA455367 AW237186 F07858 AL050090

NM_015460 AK126013 BX094817 AV697724 AA317752 AV688079 AI968571 AA318334

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for MYRIP About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13	^	14	^	15	^	16	^	17a	·	17b	·	17c
SP1:					-
SP2:					-																		-
SP3:
SP4:					-		-
SP5:					-																		-		-

ECgene alternative splicing isoforms for MYRIP

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MYRIP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATATGCAC

About this image

MYRIP expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Blood Brain Barrier

Adult Endothelial Cells

Blood Brain Barrier, Endothelium

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)

Blood, Endothelium

PureStem™ endothelial Progenitor 30-SM2-3 (Embryonic Progenitor Cell)

Blood, Endothelium

PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)

Endothelium

PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)

Endothelium

See MYRIP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYRIP

SOURCE GeneReport for Unigene cluster: Hs.594535

UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9

Tissue specificity: Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and

testis

SABiosciences Custom PCR Arrays for MYRIP

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MYRIP gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Myrip^{1 , 5}	myosin VIIA and Rab interacting protein^{1, 5}	81.77(n)¹ 80.33(a)¹		9 (71.50 cM)⁵ 245049¹ NM_144557.5¹ NP_653140.1¹ 120303936⁵
chicken (Gallus gallus)	Aves	MYRIP¹	myosin VIIA and Rab interacting protein	69.15(n) 66.86(a)		428455 XM_426015.3 XP_426015.3
lizard (Anolis carolinensis)	Reptilia	-- --	--	74(a) 61(a)	many → 1 many → 1	GL343224.1(1768359-1768574) GL343224.1(1658224-1715156)
zebrafish (Danio rerio)	Actinopterygii	myrip¹	myosin VIIA and Rab interacting protein	56.07(n) 50.4(a)		567049 XM_690337.4 XP_695429.4

ENSEMBL Gene Tree for MYRIP (if available)
TreeFam Gene Tree for MYRIP (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MYRIP gene

MLPH² MOBP²

3 SIMAP similar genes for MYRIP using alignment to 3 protein entries: MYRIP_HUMAN (see all proteins):

MLPH MOBP SYTL4

MYRIP for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs17079659^1,2	C,F,H	--	39849329(+)	`TTGACA/GTTATC`	1	--	us2k¹		17		NA NS EA WA CSA	1228
rs181997855^1,2		--	39849333(+)	`CATTAC/TCCAAA`	1	--	us2k¹		0	--	--	--	--
rs185006322^1,2		--	39849348(+)	`AAATGC/TACATC`	1	--	us2k¹		0	--	--	--	--
rs9864768^1,2	C,F,H	--	39849382(+)	`GTACAG/TATTTA`	1	--	us2k¹		15		NS EA NA CSA WA	1206
rs139484169^1,2		--	39849403(+)	`GTACCC/TCCACA`	1	--	us2k¹		0	--	--	--	--
rs149691550^1,2		--	39849444(+)	`CATGCA/GTAATT`	1	--	us2k¹		0	--	--	--	--
rs144509811^1,2		--	39849653(+)	`TTGTAC/TAACAA`	1	--	us2k¹		0	--	--	--	--
rs76321594^1,2	C	--	39849704(+)	`TGTCAA/CTTTCC`	1	--	us2k¹		0	--	--	--	--
rs78601061^1,2	C	--	39849705(+)	`GTCAAA/TTTCCT`	1	--	us2k¹		0	--	--	--	--
rs74361915^1,2	C	--	39849708(+)	`AATTTA/CCTTGA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MYRIP (39850405 - 40100405 bp, first 250kb of MYRIP)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MYRIP
1 CNV: 91287
1 Indel: 42611

SABiosciences Cancer Mutation PCR Assays

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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MYRIP for disorders           About GeneDecksing

OMIM gene information: 611790    OMIM disorders: --

3 diseases for MYRIP:    About MalaCards

Human Genome Epidemiology (HuGE) Navigator: MYRIP (2 documents)

Export disorders for MYRIP gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for MYRIP gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with MYRIP)

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Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin. (PubMed id 12221080)^{1, 2, 3, 9} Fukuda M. and Kuroda T.S. (2002)
MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes. (PubMed id 11964381)^{1, 2, 3} El-Amraoui A.... Petit C. (2002)
MyRIP anchors protein kinase A to the exocyst complex. (PubMed id 17827149)^{1, 2} Goehring A.S....Scott J.D. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane. (PubMed id 22396429)¹ Huet S....Desnos C. (2012)
Myosin Va acts in concert with Rab27a and MyRIP to re gulate acute von-Willebrand factor release from endothelial cells. (PubMed id 21740491)¹ Rojo Pulido I....Gerke V. (2011)
Whole genome association scan for genetic polymorphis ms influencing information processing speed. (PubMed id 21130836)¹ Luciano M....Deary I.J. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Genome-wide association identifies SKIV2L and MYRIP a s protective factors for age-related macular degeneration. (PubMed id 20861866)¹ Kopplin L.J....Iyengar S.K. (2010)
Rab27a and MyRIP regulate the amount and multimeric s tate of VWF released from endothelial cells. (PubMed id 19270261)¹ Nightingale T.D....Cutler D.F. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 25924	HGNC: 19156	AceView: MYRIP	Ensembl:ENSG00000170011	euGenes: HUgn25924
ECgene: MYRIP	H-InvDB: MYRIP

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for MYRIP	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MYRIP gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MYRIP gene:
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GeneCards and IP:
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myosin VIIA and Rab interacting protein

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