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Aliases for MYRFL Gene

Aliases for MYRFL Gene

  • Myelin Regulatory Factor-Like 2 3 5
  • C12orf15 3 4
  • C12orf28 3 4
  • Chromosome 12 Open Reading Frame 15 2
  • Chromosome 12 Open Reading Frame 28 2
  • Bcm1377 3

External Ids for MYRFL Gene

Previous HGNC Symbols for MYRFL Gene

  • C12orf15
  • C12orf28

Previous GeneCards Identifiers for MYRFL Gene

  • GC12P070221

Summaries for MYRFL Gene

GeneCards Summary for MYRFL Gene

MYRFL (Myelin Regulatory Factor-Like) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MYRF.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYRFL Gene

Genomics for MYRFL Gene

Regulatory Elements for MYRFL Gene

Enhancers for MYRFL Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MYRFL on UCSC Golden Path with GeneCards custom track

Genomic Location for MYRFL Gene

69,824,569 bp from pter
69,959,097 bp from pter
134,529 bases
Plus strand

Genomic View for MYRFL Gene

Genes around MYRFL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MYRFL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MYRFL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYRFL Gene

Proteins for MYRFL Gene

  • Protein details for MYRFL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Myelin regulatory factor-like protein
    Protein Accession:

    Protein attributes for MYRFL Gene

    910 amino acids
    Molecular mass:
    101670 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB71571.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for MYRFL Gene

Proteomics data for MYRFL Gene at MOPED

Post-translational modifications for MYRFL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MYRFL Gene

No data available for DME Specific Peptides for MYRFL Gene

Domains & Families for MYRFL Gene

Protein Domains for MYRFL Gene

Suggested Antigen Peptide Sequences for MYRFL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 NDT80 DNA-binding domain.
  • Belongs to the MRF family.
  • Contains 1 NDT80 DNA-binding domain.
  • Contains 1 peptidase S74 domain.
  • Belongs to the MRF family.
genes like me logo Genes that share domains with MYRFL: view

No data available for Gene Families for MYRFL Gene

Function for MYRFL Gene

Phenotypes for MYRFL Gene

genes like me logo Genes that share phenotypes with MYRFL: view

Animal Models for MYRFL Gene

MGI Knock Outs for MYRFL:

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for MYRFL Gene

Localization for MYRFL Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYRFL Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MYRFL Gene

Pathways & Interactions for MYRFL Gene

SuperPathways for MYRFL Gene

No Data Available

Interacting Proteins for MYRFL Gene

Gene Ontology (GO) - Biological Process for MYRFL Gene


No data available for Pathways by source and SIGNOR curated interactions for MYRFL Gene

Drugs & Compounds for MYRFL Gene

No Compound Related Data Available

Transcripts for MYRFL Gene

mRNA/cDNA for MYRFL Gene

(27) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MYRFL Gene

Myelin regulatory factor-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MYRFL Gene

No ASD Table

Relevant External Links for MYRFL Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MYRFL Gene

mRNA expression in normal human tissues for MYRFL Gene

mRNA differential expression in normal tissues according to GTEx for MYRFL Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x18.8) and Testis (x4.2).

Protein differential expression in normal tissues from HIPED for MYRFL Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MYRFL Gene

SOURCE GeneReport for Unigene cluster for MYRFL Gene Hs.253773

genes like me logo Genes that share expression patterns with MYRFL: view

Protein tissue co-expression partners for MYRFL Gene

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MYRFL Gene

Orthologs for MYRFL Gene

This gene was present in the common ancestor of animals.

Orthologs for MYRFL Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MYRFL 35
  • 88.44 (n)
  • 86.1 (a)
  • 19 (a)
(Canis familiaris)
Mammalia MYRFL 35
  • 87.39 (n)
  • 86.77 (a)
  • 33 (a)
(Mus musculus)
Mammalia Myrfl 35
  • 84.05 (n)
  • 84.6 (a)
Myrfl 16
Myrfl 36
  • 20 (a)
(Pan troglodytes)
Mammalia MYRFL 35
  • 99.41 (n)
  • 98.96 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Myrfl 35
  • 80.61 (n)
  • 79.44 (a)
(Monodelphis domestica)
Mammalia MYRFL 36
  • 19 (a)
(Ornithorhynchus anatinus)
Mammalia MYRFL 36
  • 12 (a)
(Gallus gallus)
Aves MYRFL 35
  • 70.63 (n)
  • 66.05 (a)
  • 12 (a)
(Anolis carolinensis)
Reptilia MYRFL 36
  • 13 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia myrfl 35
  • 66.28 (n)
  • 62.77 (a)
(Danio rerio)
Actinopterygii LOC100329855 35
  • 57.91 (n)
  • 55.7 (a)
  • 8 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3328 36
  • 2 (a)
(Caenorhabditis elegans)
Secernentea pqn-47 35
  • 45.11 (n)
  • 35.33 (a)
F21A10.2 36
  • 4 (a)
pqn-47 36
  • 4 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 1 (a)
Species with no ortholog for MYRFL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MYRFL Gene

Gene Tree for MYRFL (if available)
Gene Tree for MYRFL (if available)

Paralogs for MYRFL Gene

Paralogs for MYRFL Gene

(2) SIMAP similar genes for MYRFL Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with MYRFL: view

Variants for MYRFL Gene

Sequence variations from dbSNP and Humsavar for MYRFL Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs11177991 - 69,952,145(+) GAAAT(A/G/T)CACTC nc-transcript-variant, reference, missense
rs35051828 - 69,936,576(+) CTCTT(C/T)AAGTC nc-transcript-variant, reference, missense
rs10879065 - 69,957,904(+) AAGGG(A/C)TGGAA reference, missense
rs1921075 -- 69,852,460(-) AAAAC(C/T)AATTG intron-variant
rs1948449 -- 69,921,931(+) TATAA(G/T)TCTCC intron-variant

Variation tolerance for MYRFL Gene

Gene Damage Index Score: 11.06; 92.17% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for MYRFL Gene

Disorders for MYRFL Gene

Relevant External Links for MYRFL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MYRFL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MYRFL Gene

Publications for MYRFL Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney R.J. … Gill M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MYRFL Gene

Sources for MYRFL Gene