Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MYORG Gene

Aliases for MYORG Gene

  • Myogenesis Regulating Glycosidase (Putative) 2 3
  • KIAA1161 2 3 4 5
  • Uncharacterized Family 31 Glucosidase KIAA1161 3
  • EC 3.2.1.- 4
  • NET37 3

External Ids for MYORG Gene

Previous HGNC Symbols for MYORG Gene

  • KIAA1161

Summaries for MYORG Gene

GeneCards Summary for MYORG Gene

MYORG (Myogenesis Regulating Glycosidase (Putative)) is a Protein Coding gene. Among its related pathways are Ectoderm Differentiation.

UniProtKB/Swiss-Prot for MYORG Gene

  • Putative glucosidase.

Additional gene information for MYORG Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYORG Gene

Genomics for MYORG Gene

Regulatory Elements for MYORG Gene

Enhancers for MYORG Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H034341 1.1 Ensembl ENCODE dbSUPER 11.9 +33.1 33070 5 NFIA ZIC2 YY1 OSR2 JUND ATF3 SMAD4 RCOR1 HNF4A RXRB NUDT2 MYORG C9orf24 RNU2-50P DNAI1 FAM219A DCAF12 IMPDH1P1 ENSG00000230729 RPP25L
GH09H034333 0.9 ENCODE dbSUPER 12.1 +42.3 42336 1 SOX5 SOX13 GATAD2A SAP130 SP5 ARID4B EBF1 ZNF644 SSRP1 ZGPAT NUDT2 MYORG C9orf24 CNTFR UBAP1 GC09P034356
GH09H034346 0.9 ENCODE dbSUPER 11.9 +29.5 29468 1 SCRT1 MAX ZNF384 NR2F2 YY1 JUND SCRT2 HNF4G ZBTB33 HNF4A MYORG C9orf24 RNU2-50P DNAI1 FAM219A IMPDH1P1 DCAF12 ENSG00000230729 RPP25L KIF24
GH09H034332 0.7 ENCODE 12.1 +44.3 44349 0 CTCF ZNF654 PKNOX1 ARID4B REST RAD21 ZNF316 MAFF SMC3 HNF4A MYORG C9orf24 CNTFR NUDT2 GC09P034356
GH09H033620 1.1 Ensembl ENCODE 4.8 +755.8 755786 2 LEF1 ATF1 ARNT BACH1 CEBPG ZNF316 FOXK2 ZNF366 POLR2A ZNF600 ENSG00000260947 TRBV24OR9-2 CYP4F26P MYORG PIR37945 ANXA2P2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MYORG on UCSC Golden Path with GeneCards custom track

Promoters for MYORG Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000234518 -104 1601 HDGF PKNOX1 FOXA2 ATF1 MLX ARID4B SIN3A YY1 ETS1 GLIS2

Genomic Location for MYORG Gene

Chromosome:
9
Start:
34,366,666 bp from pter
End:
34,376,896 bp from pter
Size:
10,231 bases
Orientation:
Minus strand

Genomic View for MYORG Gene

Genes around MYORG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MYORG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MYORG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYORG Gene

Proteins for MYORG Gene

  • Protein details for MYORG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NSJ0-K1161_HUMAN
    Recommended name:
    Uncharacterized family 31 glucosidase KIAA1161
    Protein Accession:
    Q6NSJ0
    Secondary Accessions:
    • Q5T587
    • Q5T588
    • Q9ULQ9

    Protein attributes for MYORG Gene

    Size:
    714 amino acids
    Molecular mass:
    81087 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI15965.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI15966.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for MYORG Gene

Post-translational modifications for MYORG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MYORG Gene

No data available for DME Specific Peptides for MYORG Gene

Domains & Families for MYORG Gene

Gene Families for MYORG Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for MYORG Gene

Suggested Antigen Peptide Sequences for MYORG Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6NSJ0

UniProtKB/Swiss-Prot:

K1161_HUMAN :
  • Belongs to the glycosyl hydrolase 31 family.
Family:
  • Belongs to the glycosyl hydrolase 31 family.
genes like me logo Genes that share domains with MYORG: view

Function for MYORG Gene

Molecular function for MYORG Gene

UniProtKB/Swiss-Prot Function:
Putative glucosidase.

Enzyme Numbers (IUBMB) for MYORG Gene

Gene Ontology (GO) - Molecular Function for MYORG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA --
GO:0016787 hydrolase activity IEA --
GO:0016798 hydrolase activity, acting on glycosyl bonds IEA --
genes like me logo Genes that share ontologies with MYORG: view
genes like me logo Genes that share phenotypes with MYORG: view

Animal Models for MYORG Gene

MGI Knock Outs for MYORG:

Animal Model Products

CRISPR Products

miRNA for MYORG Gene

miRTarBase miRNAs that target MYORG

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for MYORG
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MYORG Gene

Localization for MYORG Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYORG Gene

Membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MYORG gene
Compartment Confidence
nucleus 3
plasma membrane 2
golgi apparatus 2
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for MYORG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0031965 nuclear membrane IEA --
genes like me logo Genes that share ontologies with MYORG: view

Pathways & Interactions for MYORG Gene

SuperPathways for MYORG Gene

SuperPathway Contained pathways
1 Ectoderm Differentiation
genes like me logo Genes that share pathways with MYORG: view

Pathways by source for MYORG Gene

1 BioSystems pathway for MYORG Gene

Gene Ontology (GO) - Biological Process for MYORG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005975 carbohydrate metabolic process IEA --
GO:0008152 metabolic process IEA --
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IEA --
GO:0048741 skeletal muscle fiber development IEA --
GO:0051897 positive regulation of protein kinase B signaling IEA --
genes like me logo Genes that share ontologies with MYORG: view

No data available for SIGNOR curated interactions for MYORG Gene

Drugs & Compounds for MYORG Gene

No Compound Related Data Available

Transcripts for MYORG Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for MYORG
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MYORG Gene

No ASD Table

Relevant External Links for MYORG Gene

GeneLoc Exon Structure for
MYORG
ECgene alternative splicing isoforms for
MYORG

Expression for MYORG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of MYORG Gene:

MYORG

Evidence on tissue expression from TISSUES for MYORG Gene

  • Liver(4.2)
  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with MYORG: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MYORG Gene

Orthologs for MYORG Gene

This gene was present in the common ancestor of animals.

Orthologs for MYORG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1161 34 33
  • 99.11 (n)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA1161 33
  • 87.8 (n)
dog
(Canis familiaris)
Mammalia KIAA1161 34 33
  • 87.19 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1309821 33
  • 85.09 (n)
mouse
(Mus musculus)
Mammalia AI464131 33 16 34
  • 84.76 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1161 34
  • 75 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 34
  • 76 (a)
OneToMany
KIAA1161 33
  • 74.84 (n)
-- 34
  • 72 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 72 (a)
OneToMany
-- 34
  • 64 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1161 33
  • 66.47 (n)
Str.14314 33
zebrafish
(Danio rerio)
Actinopterygii si:dkey-228b2.5 34
  • 66 (a)
OneToMany
si:ch211-117c19.1 34
  • 64 (a)
OneToMany
LOC100537539 33
  • 63.39 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003993 33
  • 51.86 (n)
fruit fly
(Drosophila melanogaster)
Insecta tobi 34
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 41 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 41 (a)
OneToMany
-- 34
  • 39 (a)
OneToMany
Species where no ortholog for MYORG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MYORG Gene

ENSEMBL:
Gene Tree for MYORG (if available)
TreeFam:
Gene Tree for MYORG (if available)

Paralogs for MYORG Gene

No data available for Paralogs for MYORG Gene

Variants for MYORG Gene

Sequence variations from dbSNP and Humsavar for MYORG Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000035147 -- 34,373,318(+) GATCA(C/G)AGGAT intron-variant
rs1000107597 -- 34,374,785(+) TAGTC(C/T)CAGCT intron-variant
rs1000234117 -- 34,377,286(+) GATGA(C/G)AGGGA upstream-variant-2KB
rs1000457136 -- 34,377,032(+) GGCGG(A/C)TCTGT upstream-variant-2KB
rs1000661143 -- 34,378,749(+) CGTGG(A/G)GTGGA downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MYORG Gene

Variant ID Type Subtype PubMed ID
esv3620335 CNV gain 21293372
nsv1015595 CNV gain 25217958
nsv1016251 CNV gain 25217958
nsv1028418 CNV gain 25217958
nsv1125318 OTHER inversion 24896259
nsv831542 CNV gain 17160897

Variation tolerance for MYORG Gene

Gene Damage Index Score: 11.80; 93.39% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MYORG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MYORG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYORG Gene

Disorders for MYORG Gene

Relevant External Links for MYORG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MYORG
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MYORG

No disorders were found for MYORG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MYORG Gene

Publications for MYORG Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 2 3 4 60
  2. NET37, a nuclear envelope transmembrane protein with glycosidase homology, is involved in myoblast differentiation. (PMID: 19706595) Datta K … Gerace L (The Journal of biological chemistry 2009) 2 3 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60
  5. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4 60

Products for MYORG Gene

Sources for MYORG Gene

Content
Loading form....