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MYOM2 Gene

protein-coding   GIFtS: 53
GCID: GC08P001993

Myomesin 2

(Previous names: myomesin (M-protein) 2 (165kD), myomesin (M-protein) 2,...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Myomesin 21 2     Myomesin (M-Protein) 2 (165kD)1
Myomesin (M-Protein) 2, 165kDa1 2     TTNAP2
Myomesin Family Member 22 3     M-Band Protein2
165 KDa Connectin-Associated Protein2 3     myomesin-22
165 KDa Titin-Associated Protein2 3     Titin-Associated Protein, 165 KD2
M-protein2 3     

External Ids:    HGNC: 76141   Entrez Gene: 91722   Ensembl: ENSG000000364487   OMIM: 6035095   UniProtKB: P542963   

Export aliases for MYOM2 gene to outside databases

Previous GC identifers: GC08P001752 GC08M002086 GC08P002143 GC08P001980 GC08P001809


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MYOM2 Gene:
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres,
the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly
to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains
1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong
homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that
the MYOM2 protein and bovine M protein are identical. (provided by RefSeq, Jul 2008)

GeneCards Summary for MYOM2 Gene:
MYOM2 (myomesin 2) is a protein-coding gene. Diseases associated with MYOM2 include streptococcal toxic-shock syndrome, and rheumatic fever. GO annotations related to this gene include structural constituent of muscle. An important paralog of this gene is MYBPHL.

UniProtKB/Swiss-Prot: MYOM2_HUMAN, P54296
Function: Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This
binding is dose dependent

Gene Wiki entry for MYOM2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_023736.18  NC_018919.2  NT_187576.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the MYOM2 gene promoter:
         RFX1   FOXF2   Pax-2   MyoD   Pax-2a   LCR-F1   C/EBPalpha   CHOP-10   Pax-2b   FOXO1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMYOM2 promoter sequence
   Search Chromatin IP Primers for MYOM2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MYOM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p23.3   Ensembl cytogenetic band:  8p23.3   HGNC cytogenetic band: 8p23.3

MYOM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYOM2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P001993:  view genomic region     (about GC identifiers)

Start:
1,993,155 bp from pter      End:
2,113,475 bp from pter
Size:
120,321 bases      Orientation:
plus strand

1 alternative location:
Chr8+,NW_003571042 27,769-127,991     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MYOM2_HUMAN, P54296 (See protein sequence)
Recommended Name: Myomesin-2  
Size: 1465 amino acids; 164896 Da
Subunit: Interacts with TTN/titin (By similarity)
Secondary accessions: Q7Z3Y2

Explore the universe of human proteins at neXtProt for MYOM2: NX_P54296

Explore proteomics data for MYOM2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MYOM2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003961.2  
    ENSEMBL proteins: 
     ENSP00000262113   ENSP00000428396  

    MYOM2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FN3: Fibronectin type III domain containing
    ISET: Immunoglobulin superfamily / I-set domain containing
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    Selected InterPro protein domains (see all 6):
     IPR003598 Ig_sub2
     IPR003961 Fibronectin_type3
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom

    Graphical View of Domain Structure for InterPro Entry P54296

    ProtoNet protein and cluster: P54296

    3 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB003962 Fibronectin type III repeat signature
    IPB013098 Immunoglobulin I-set


    UniProtKB/Swiss-Prot: MYOM2_HUMAN, P54296
    Similarity: Contains 5 fibronectin type-III domains
    Similarity: Contains 5 Ig-like C2-type (immunoglobulin-like) domains


    MYOM2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MYOM2_HUMAN, P54296
    Function: Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This
    binding is dose dependent

         Genatlas biochemistry entry for MYOM2:
    sarcomeric M-band protein,myomesin 2,binding the globular head of titin and the central region of light
    meromyosin,Ig superfamily,transiently expressed in all developing skeletal muscle fibers,subsequently
    down-regulated and finally expressed again only in adult cardiac and fast skeletal muscles fibers

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008307structural constituent of muscle TAS7505783
         
    MYOM2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MYOM2
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MYOM2_HUMAN, P54296: Cytoplasm, myofibril, sarcomere, M line (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton3
    mitochondrion3
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0031430M band IEA--
    GO:0032982myosin filament IEA--

    MYOM2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MYOM2
    Interactions:

        Search GeneGlobe Interaction Network for MYOM2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for MYOM2 (P542961, 3 ENSP000002621134) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CKMP067323, ENSP000002214764I2D: score=1 STRING: ENSP00000221476
    MYH9P355793, ENSP000002161814I2D: score=1 STRING: ENSP00000216181
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    ACTN2P356091EBI-5357134,EBI-77797
    DYSFO759231EBI-5357134,EBI-2799016
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006936muscle contraction IEA--

    MYOM2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MYOM2

    2 Novoseek inferred chemical compound relationships for MYOM2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hyaluronic acid 49 1 8903312 (1)
    fibrinogen 16.3 3 8275054 (1), 7569776 (1)



    MYOM2 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MYOM2 gene: 
    NM_003970.2  

    Unigene Cluster for MYOM2:

    Myomesin 2
    Hs.443683  [show with all ESTs]
    Unigene Representative Sequence: NM_003970
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262113(uc003wpx.4 uc011kwi.2) ENST00000523438 ENST00000519518
    ENST00000518803 ENST00000519372 ENST00000518203 ENST00000517520 ENST00000523443
    ENST00000520072 ENST00000519631 ENST00000523595 ENST00000519268 ENST00000520298
    ENST00000520779 ENST00000518513
    miRNA
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    GenScript: all cDNA clones in your preferred vector: MYOM2 (NM_003970)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYOM2
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat MYOM2
      QuantiFast Probe-based Assays in human, mouse, rat MYOM2

    Additional mRNA sequence: 

    AK297890.1 BC052969.1 X69089.1 

    8 DOTS entries:

    DT.114269  DT.40116833  DT.100679255  DT.101956413  DT.102828258  DT.447999  DT.92019729  DT.95108195 

    Selected AceView cDNA sequences (see all 102):

    BM720057 BF063120 BM709069 AJ712046 F36638 BX094800 BX455670 BI917023 
    F04076 BX507467 AI186799 BM713936 N78805 BC052969 CD617771 CD617773 
    BM040745 CK004918 C03894 AW027783 BQ956106 BM665811 CB128597 AJ712023 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MYOM2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTACCTGG
    MYOM2 Expression
    About this image


    MYOM2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Primitive Streak (Early Embryonic Tissues)    fully expand to see all 2 entries
             Notochord Cells Notochord
             Notochord
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mandibular Arch Muscles
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Notochord Cells Notochord
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
     
     Epithelial Cells
             Podocytes Podocyte Layer
    MYOM2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MYOM2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.443683
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MYOM2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Myom21 , 5 myomesin 21, 5 82.42(n)1
    89.4(a)1
      8 (7.63 cM)5
    179301  NM_008664.21  NP_032690.21 
     150576535 
    chicken
    (Gallus gallus)
    Aves MYOM21 myomesin (M-protein) 2, 165kDa 70.53(n)
    72.79(a)
      396034  NM_205135.1  NP_990466.1 
    lizard
    (Anolis carolinensis)
    Reptilia MYOM26
    myomesin 2
    73(a)
    1 ↔ 1
    1(158395438-158487702)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.242142 Xenopus laevis transcribed sequence with weak similarity more 74.26(n)    BQ732496.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wu:fi38e051 wu:fi38e05 60.38(n)
    55.23(a)
      334269  XM_003199440.2  XP_003199488.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta sls6
    CG149646
    --
    2(a)
    12(a)
    many ↔ many
    many ↔ many
    3L(2039681-2115611)
    3L(3172817-3178580)


    ENSEMBL Gene Tree for MYOM2 (if available)
    TreeFam Gene Tree for MYOM2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MYOM2 gene
    MYBPHL2  MYBPC32  MYOM12  MYOM32  IGSF222  MYBPH2  IGFN12  MYBPC22  
    MYBPC12  
    3 SIMAP similar genes for MYOM2 using alignment to 2 protein entries:     MYOM2_HUMAN (see all proteins):
    MYOM3    MYOM1    KIAA0992

    MYOM2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MYOM2 (see all 4463)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1158828501,2
    C,F--1991210(+) CTATCT/CGTGTC 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1180129481,2
    C,F--1991272(+) TTAGAC/TGCAGC 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs48759291,2
    C,F,A,H--1991352(-) AGGAAG/AGGCCA 1 -- us2k1 trp318Minor allele frequency- A:0.29NA NS EA WA CSA 923
    rs746193111,2
    F--1991379(+) CCTCCC/TCGGGA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs177509801,2
    C,F,H--1991386(+) GGGATG/AAGATT 1 -- us2k120Minor allele frequency- A:0.11NA NS EA WA 2400
    rs1915679241,2
    --1991504(+) TCCAGG/TGTCGG 1 -- us2k10--------
    rs736577121,2
    C,F--1991507(+) AGTGTC/TGGCCA 1 -- us2k12Minor allele frequency- T:0.06WA 120
    rs347812821,2
    C--1991640(+) TTTGC-/AACCCC 1 -- us2k10--------
    rs1436548031,2
    C--1991641(+) TTGCA-/AC/C  
            
    CCCCC
    1 -- us2k10--------
    rs344973441,2
    C--1991643(+) CAACC-/TCCCCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MYOM2 (1993155 - 2113475 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MYOM2 (see all 73):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1967473CNV Deletion18987734
    esv2736389CNV Deletion23290073
    esv2736373CNV Deletion23290073
    esv2433339CNV Deletion19546169
    esv1094537CNV Deletion17803354
    esv2108954CNV Deletion18987734
    esv2661335CNV Deletion23128226
    esv3586CNV Deletion18987735
    esv2736387CNV Deletion23290073
    nsv820985CNV Deletion20802225

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MYOM2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603509    OMIM disorders: --

    Selected diseases for MYOM2 (see all 21):    
    About MalaCards
    streptococcal toxic-shock syndrome    rheumatic fever    toxic shock syndrome    poems syndrome
    subacute sclerosing panencephalitis    bacteremia    aggressive periodontitis    pharyngitis
    myeloma    amyloidosis    measles    periodontitis
    multiple myeloma    pertussis    pulmonary function    laryngitis
    chronic lymphocytic leukemia    bipolar disorder    arthritis    schizophrenia


    MYOM2 for disorders           About GeneDecksing

    6 Novoseek inferred disease relationships for MYOM2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    monoclonal gammopathy 73.8 2 14616966 (1), 19673884 (1)
    acute rheumatic fever 69.2 2 2016540 (1), 16421785 (1)
    toxic shock syndrome 38.8 1 8335368 (1)
    skin infection 38.1 1 10678929 (1)
    myeloma 37.6 3 19673884 (1), 18069256 (1)
    necrosis 0 1 9691092 (1)

    Genetic Association Database (GAD): MYOM2

    Export disorders for MYOM2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MYOM2 gene, integrated from 10 sources (see all 76):
    (articles sorted by number of sources associating them with MYOM2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins. (PubMed id 7505783)1, 2 Vinkemeier U.... Fuerst D.O. (J. Cell Sci. 1993)
    2. Assignment of the human gene for endosarcomeric cytoskeletal M-protein (MYOM2) to 8p23.3. (PubMed id 9933576)1, 9 van der Ven P.F....FA1rst D.O. (Genomics 1999)
    3. Dysferlin interacts with calsequestrin-1, myomesin-2 and dynein in human skeletal muscle. (PubMed id 23792176)1 Flix B....Gallardo E. (amp 2013)
    4. Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. (PubMed id 20709820)4 Kong X....Pillai S.G. (Am. J. Respir. Crit. Care Med. 2011)
    5. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PubMed id 20889312)1 Wang K.S....Aragam N. (Schizophr. Res. 2010)
    6. The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (PLoS ONE 2010)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    9. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (BMC Med. Genet. 2007)
    10. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (Nature 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9172 HGNC: 7614 AceView: MYOM2 Ensembl:ENSG00000036448 euGenes: HUgn9172
    ECgene: MYOM2 H-InvDB: MYOM2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MYOM2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MYOM2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MYOM2 gene:
    Search GeneIP for patents involving MYOM2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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