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MYOD1 Gene

protein-coding GIFtS: 60

GC11P017697

myogenic differentiation 1
(Previous name: myogenic factor 3 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: MYF3)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MYF3 ^², ³, ⁵
MYOD ^¹, ², ³
Myf-3 ^³
PUM ^¹, ²
bHLHc1 ^¹, ²

Descriptions
Myogenic factor 3 ^¹, ², ³
myoblast determination protein 1 ^²
myogenic differentiation 1 ^²

External Ids
HGNC: 7611¹
Entrez Gene: 4654²
UniProtKB: P15172³
Ensembl: ENSG00000129152⁷

Search outside databases for aliases for MYOD1 gene

Previous GC identifers: GC11P018862 GC11P018683 GC11P017780 GC11P017705

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MYOD1:

This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of

transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation

by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also

involved in muscle regeneration. It activates its own transcription which may stabilize commitment

to myogenesis. [provided by RefSeq]

UniProtKB/Swiss-Prot: MYOD1_HUMAN, P15172

Function: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to

differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited

by the twist protein. This interaction probably involves the basic domains of both proteins (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MYOD1 gene

Entrez Gene cytogenetic band: 11p15.4 Ensembl cytogenetic band: 11p15.1 HGNC cytogenetic band: 11p15

MYOD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P017697: (about GC identifiers)

Start:	17,697,686 bp from pter
End:	17,700,254 bp from pter
Size:	2,569 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_009237.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MYOD1_HUMAN, P15172 (See protein sequence)

Recommended Name: Myoblast determination protein 1

Size: 320 amino acids; 34501 Da

Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Seems to form

active heterodimers with ITF-2. Interacts with SUV39H1

Subcellular location: Nucleus

Secondary accessions: O75321

Post-translational modifications:

Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target

genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity)¹

Ubiquitinated on the N-terminus; which is required for proteasomal degradation¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002469.2

ENSEMBL proteins:

ENSP00000250003

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MyoD1)
	Human Recombinant Proteins from Abnova (MYOD1)

OriGene Purified Recombinant Human Protein: MYOD1

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	TAS	3175662
GO:0005667	transcription factor complex	IEA	--

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Antibodies for MYOD1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of MYOD1
	Sigma-Aldrich Antibodies for MYOD1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (MyoD1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MYOD1)
	Novus Biologicals Antibodies for MYOD1

Assays for MYOD1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P15172

ProtoNet protein and cluster: P15172

2 Blocks protein families:

IPB001092 Basic helix-loop-helix dimerization domain bHLH

IPB002546 Myogenic basic muscle-specific protein

UniProtKB/Swiss-Prot: MYOD1_HUMAN, P15172

Similarity: Contains 1 basic helix-loop-helix (bHLH) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MYOD1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MYOD1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002478

Applied Biosystems Silencer® siRNAs for MYOD1

Sigma-Aldrich siRNA for MYOD1

Sigma-Aldrich shRNA for MYOD1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for MYOD1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002478
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002478
untagged cDNA clone in CMV expression vector: NM_002478

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002478

UniProtKB/Swiss-Prot: MYOD1_HUMAN, P15172

Function: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to

differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited

by the twist protein. This interaction probably involves the basic domains of both proteins (By

myogenic differentiation 1,transcription activator of muscle specific genes,promoting cell cycle

exit by inducing CDKNIA

12 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Myod1):

	adipose tissue	growth/size	lethality-postnatal	lethality-prenatal/perinatal
life span-post-weaning/aging	muscle	no phenotypic analysis	normal	reproductive system
respiratory system	skeleton

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding	TAS	1846704
GO:0003713	transcription coactivator activity	TAS	1846704
GO:0008134	transcription factor binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for MYOD1

5/155 Interacting proteins for MYOD1 (ENSP00000250003³ P15172^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 155 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SRF	P11831²	STRING (score=.996) MINT-15522 MINT-15523
SMAD4	Q13485²	STRING (score=.947) MINT-61952
SMAD7	O15105²	STRING (score=.925) MINT-61815
TCF3	P15923-1¹	STRING (score=.999) EBI-488878, EBI-769645
EP300	ENSP00000263253³	STRING (score=.998)

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5/11 Gene Ontology (GO) biological process terms (links to tree view) (see all 11 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	IEA	--
GO:0006468	protein amino acid phosphorylation	TAS	3175662
GO:0007275	multicellular organismal development	IEA	--
GO:0007517	muscle development	TAS	1846704
GO:0007518	myoblast cell fate determination	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MYOD1
10/25 Novoseek chemical compound relationships for MYOD1 gene (see all 25 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
chlorate	33.65	1	11784020 (1)
bromodeoxyuridine	25.08	1	16750930 (1)
threonine	18.73	4	9804168 (1), 1651276 (1), 9418854 (1)
lithium chloride	7.95	1	16162663 (1)
atp	5.17	1	16778569 (1)
12-o-tetradecanoylphorbol 13-acetate	3.07	7	8395398 (2), 7547506 (2), 17468105 (1)
calcium	1.48	2	7794894 (1), 17111365 (1)
tgf beta1	1.26	1	15056073 (1)
glucose	0.91	3	16778569 (1), 15516373 (1)
oxygen	0.22	3	14997318 (1), 18364460 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MYOD1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MYOD1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002478

Sigma-Aldrich siRNA for MYOD1

Sigma-Aldrich shRNA for MYOD1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002478

REFSEQ mRNAs for MYOD1 gene:

NM_002478.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002478

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002478
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002478
                                 untagged cDNA clone in CMV expression vector: NM_002478

Additional cDNA sequence:

AK314968.1 BC064493.1 BT007157.1 CR612159.1 X17650.1 X56677.1

4 DOTS entries:

DT.100828831 DT.95218213 DT.86848246 DT.91770652

24/86 AceView cDNA sequences (see all 86 ):

BI115390 NM_002478 AI300241 BE296570 CR612159 BC064493 BE019098 BG828208

BF309303 BF204506 BE298382 BE250705 BF205585 BI114877 BF204151 BE299732

BF304451 BI114827 BX283932 BE297539 BE019350 BF205507 BU738397 BG827263

highest scoring ESTs for MYOD1:

BC064493 BE250506 BE296570 BE299484 BE299697 BE299732 BE299768 BE300295 BF203994 BF204151

Unigene Cluster for MYOD1:

Myogenic differentiation 1

Hs.181768 [show with all ESTs]

Unigene Representative Sequence: NM_002478

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000250003

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MYOD1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MYOD1

¹ / ² / ³

3 probe-sets matching MYOD1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33482_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AF027148	0.20	1.00	0.72	1
206657_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002478	0.60	1.00	0.82	1
206657_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks MYOD1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTGTGTGGTG

SOURCE GeneReport for Unigene cluster: Hs.181768
Expression variation in blood from EXPOLDB for MYOD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MYOD1 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MYOD1¹	--	myogenic differentiation 1	89.97(n) 93.1(a)	611940 XM_849663.1 XP_854756.1
chimpanzee (Pan troglodytes)	MYOD1¹	--	myogenic differentiation 1	99.48(n) 99.37(a)	451057 XM_508311.2 XP_508311.2
cow (Bos taurus)	MYOD1¹	--	myogenic differentiation 1	88.78(n) 92.14(a)	281938 NM_001040478.2 NP_001035568.2
rat (Rattus norvegicus)	Myod1¹	--	myogenic differentiation 1	84.7(n) 87.74(a)	337868 NM_176079.1 NP_788268.1
mouse (Mus musculus)	Myod1^{1, 5}	7 (23.50 cM)⁵	myogenic differentiation 1^{1, 5}	85.32(n)¹ 88.68(a)¹	17927¹ NM_010866.1¹ NP_034996.1¹ AI503393⁵ AK076157⁵ (see all 12)

About this table Species with no ortholog for MYOD1

ENSEMBL Gene Tree for MYOD1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MYOD1 gene

MYF5² MYOG² MYF6²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/25 NCBI SNPs in MYOD1 are shown (see all 25 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 30)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs3911833^1,2	C,F,H	17697354(-)	`TCTGAG/ACTGAC`	1	--	ng5¹		4		EU EA WA	418
--	rs7107526^1,2	A,C	17700525(+)	`CTCGCC/TCCCTA`	1	--	ng3¹		0	--	--	--	--
	rs2734549^1,2	F	17697786(+)	`GTGGGC/GATTCA`	1	--	ut5¹		1		MN	184
	rs2734556^1,2	H	17695878(+)	`TGCTGC/GCTCTG`	1	--	ng5¹		4		EU EA WA	412
	rs10832853^1,2	A	17699257(+)	`CTTTTC/GGATTG`	1	--	int¹		0	--	--	--	--
	rs2526547^1,2	A	17698896(-)	`TGGTTC/GGGGGG`	1	--	int¹		0	--	--	--	--
--	rs2734557^1,2	--	17696799(+)	`GGAACC/GAAGCC`	1	--	ng5¹		0	--	--	--	--
	rs1042806^1,2	--	17700158(+)	`AGGCAG/TGGTGT`	1	--	ut3¹		0	--	--	--	--
--	rs66928907^1,2	--	17697575(+)	`CCCCA-/CAGCCC`	1	--	ng5¹		0	--	--	--	--
--	rs7121212^1,2	--	17696848(+)	`TCAGCC/TTAGAC`	1	--	ng5¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for MYOD1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 159970

10/32 Novoseek disease relationships for MYOD1 gene (see all 32 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
rhabdomyosarcoma	79.50	49	19299559 (5), 2260621 (5), 8383879 (5), 12783965 (2) (see all 25)
rhabdomyosarcoma embryonal	64.17	5	16010486 (1), 18656317 (1), 19299559 (1), 16220232 (1)
rhabdomyosarcoma alveolar	57.09	1	9256013 (1)
sarcoma alveolar soft part	51.10	6	10383802 (4), 12778001 (1), 1656801 (1)
rhabdoid tumor	46.77	1	2260621 (1)
sarcoma extraosseous ewings	46.21	1	2260621 (1)
retinoblastoma	42.12	5	7970718 (2), 12665587 (1), 10601020 (1), 8400456 (1)
ewings sarcoma	39.37	5	12426678 (2), 10227726 (1), 2260621 (1), 7495304 (1)
hypertrophy	37.01	4	12716875 (1), 17661068 (1), 17395765 (1), 10370140 (1)
muscular dystrophies	36.16	1	18334989 (1)

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Tumor Gene Database: MYOD1

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/536 PubMed articles for MYOD1 gene (see all 536 ):

Control of muscle development by dueling HATs and HDACs. (PubMed id 11532390)^{1, 3, 4} McKinsey T.A.... Olson E.N. (2001)
Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation. (PubMed id 16858404)^{3, 4} Mal A.K. (2006)
A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein. (PubMed id 9774340)^{3, 4} Breitschopf K.... Ciechanover A. (1998)
Methylation alterations of the MyoD1 upstream region are predictive of subclassification of human rhabdomyosarcomas. (PubMed id 9546368)^{3, 4} Chen B.... Parham D.M. (1998)
Human MyoD: cDNA and deduced amino acid sequence. (PubMed id 1850513)^{3, 4} Pearson-White S.H. (1991)
Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products. (PubMed id 2583111)^{3, 4} Braun T....Arnold H.H. (1989)
Phosphorylation of nuclear MyoD is required for its rapid degradation. (PubMed id 9710583)^{1, 3} Song A....Harrington M.A. (1998)
Direct inhibition of G(1) cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation. (PubMed id 10601020)^{1, 3} Zhang J.M....Paterson B.M. (1999)
MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state. (PubMed id 19299559)^{1, 3} Yang Z....Tapscott S.J. (2009)
Analysis of the DNA-binding properties of MyoD, myogenin, and E12 by fluorescence anisotropy. (PubMed id 12196028)^{1, 3} Maleki S.J....Hurlburt B.K. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4654	HGNC: 7611	AceView: MYOD1	Ensembl:ENSG00000129152	euGenes: HUgn4654
ECgene: MYOD1	H-InvDB: MYOD1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MYOD1	Genetics and Cytogenetics in Oncology and Haematology
Wikipedia	http://en.wikipedia.org/wiki/MyoD

Licensable Technologies for MYOD1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for MYOD1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MYOD1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MYOD1		Antibodies for MYOD1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MYOD1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MYOD1)
	Antibodies (MYOD1)
	Chimera RNAi (MYOD1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (MyoD1)
	Antibodies (MyoD1)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for MYOD1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for MYOD1

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MYOD1 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for MYOD1

Summaries
for MYOD1

Genomic Location
for MYOD1

Proteins
for MYOD1

Protein Domains/
Families
for MYOD1

Gene Function
for MYOD1

Pathways & Interactions
for MYOD1

Drugs & Compounds
for MYOD1

Transcripts
for MYOD1

Expression
for MYOD1

Orthologs
for MYOD1

Paralogs
for MYOD1

SNPs/Variants
for MYOD1

Disorders & Mutations
for MYOD1

Medical News
for MYOD1

Publications
for MYOD1

Search for MYOD1

Genome Databases showing MYOD1

Other Databases showing MYOD1

Specialized Databases showing MYOD1

Licensable Technologies
for MYOD1

Services
for MYOD1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MYOD1 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor MYOD1

Summariesfor MYOD1

Genomic Locationfor MYOD1

Proteinsfor MYOD1

Protein Domains/Familiesfor MYOD1

Gene Functionfor MYOD1

Pathways & Interactionsfor MYOD1

Drugs & Compoundsfor MYOD1

Transcriptsfor MYOD1

Expression for MYOD1

Orthologsfor MYOD1

Paralogsfor MYOD1

SNPs/Variantsfor MYOD1

Disorders & Mutationsfor MYOD1

Medical Newsfor MYOD1

Publicationsfor MYOD1

Search for MYOD1

Genome Databases showing MYOD1

Other Databases showing MYOD1

Specialized Databases showing MYOD1

Licensable Technologiesfor MYOD1

Servicesfor MYOD1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MYOD1

Summaries
for MYOD1

Genomic Location
for MYOD1

Proteins
for MYOD1

Protein Domains/
Families
for MYOD1

Gene Function
for MYOD1

Pathways & Interactions
for MYOD1

Drugs & Compounds
for MYOD1

Transcripts
for MYOD1

Expression
for MYOD1

Orthologs
for MYOD1

Paralogs
for MYOD1

SNPs/Variants
for MYOD1

Disorders & Mutations
for MYOD1

Medical News
for MYOD1

Publications
for MYOD1

Licensable Technologies
for MYOD1

Services
for MYOD1