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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MYO9A Gene

protein-coding   GIFtS: 54
GCID: GC15M072114

Myosin IXA

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Myosin IXA1 2
Unconventional Myosin-9a2 3
myosin-IXa2
Unconventional Myosin-IXa2
MYR73

External Ids:    HGNC: 76081   Entrez Gene: 46492   Ensembl: ENSG000000669337   OMIM: 6048755   UniProtKB: B2RTY43   

Export aliases for MYO9A gene to outside databases

Previous GC identifers: GC15M067913 GC15M065216 GC15M069694 GC15M069834 GC15M069905 GC15M048948


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MYO9A Gene:
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should
not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic
domains of conventional myosins and are further distinguished from class members by their tail domains. They
function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome.
(provided by RefSeq, Dec 2011)

GeneCards Summary for MYO9A Gene: 
MYO9A (myosin IXA) is a protein-coding gene. Diseases associated with MYO9A include bardet-biedl syndrome, and intrahepatic cholangiocarcinoma, and among its related super-pathways are Antioxidant Action of Vitamin-C and Actin Nucleation and Branching. GO annotations related to this gene include motor activity and actin binding. An important paralog of this gene is MYO3A.

UniProtKB/Swiss-Prot: MYO9A_HUMAN, B2RTY4
Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in
intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology
and function (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYO9A gene promoter:
         Sp1   SREBP-1c   CUTL1   HNF-1A   SREBP-1b   CREB   SREBP-1a   HNF-1   deltaCREB   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMYO9A promoter sequence
   Search SABiosciences Chromatin IP Primers for MYO9A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYO9A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22-q23   Ensembl cytogenetic band:  15q23   HGNC cytogenetic band: 15q22-q23

MYO9A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYO9A gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M072114:  view genomic region     (about GC identifiers)

Start:
72,114,632 bp from pter      End:
72,410,918 bp from pter
Size:
296,287 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MYO9A_HUMAN, B2RTY4 (See protein sequence)
Recommended Name: Unconventional myosin-IXa  
Size: 2548 amino acids; 292706 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Caution: Represents a unconventional myosin. This protein should not be confused with the conventional myosin-9
(MYH9)
Sequence caution: Sequence=BAA91979.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB14517.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B0I1T5 C9IYB3 C9JA86 Q14787 Q3YLD7 Q3YLD8 Q6P986 Q9H8T5 Q9NTG2 Q9NUY2
Q9UEP3 Q9UNJ2
Alternative splicing: 5 isoforms:  B2RTY4-1   B2RTY4-2   B2RTY4-3   B2RTY4-4   B2RTY4-5   (Lacks the ATP-binding domain which suggests that it cannot interact with actin)

Explore the universe of human proteins at neXtProt for MYO9A: NX_B2RTY4

Explore proteomics data for MYO9A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_B2RTY4

  • MYO9A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MYO9A Protein Expression
    REFSEQ proteins: NP_008832.2  
    ENSEMBL proteins: 
     ENSP00000348349   ENSP00000457945   ENSP00000457407   ENSP00000456192   ENSP00000455150  
     ENSP00000454446   ENSP00000457235   ENSP00000454517   ENSP00000456882   ENSP00000399162  
     ENSP00000398250  
    Reactome Protein details: B2RTY4
    Human Recombinant Protein Products for MYO9A: 
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    Cloud-Clone Corp. Proteins for MYO9A 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0016021integral to membrane IEA--
    GO:0016459myosin complex ----
    GO:0016461unconventional myosin complex NAS8022818

    MYO9A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MYOIX: Myosins / Myosin superfamily : Class IX

    5/7 InterPro protein domains (see all 7):
     IPR008936 Rho_GTPase_activation_prot
     IPR000159 Ras-assoc
     IPR027417 P-loop_NTPase
     IPR000048 IQ_motif_EF-hand-BS
     IPR002219 Prot_Kinase_C-like_PE/DAG-bd

    Graphical View of Domain Structure for InterPro Entry B2RTY4

    ProtoNet protein and cluster: B2RTY4

    UniProtKB/Swiss-Prot: MYO9A_HUMAN, B2RTY4
    Similarity: Contains 5 IQ domains
    Similarity: Contains 2 myosin head-like domains
    Similarity: Contains 2 phorbol-ester/DAG-type zinc fingers
    Similarity: Contains 1 Ras-associating domain
    Similarity: Contains 1 Rho-GAP domain


    MYO9A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MYO9A_HUMAN, B2RTY4
    Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in
    intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology
    and function (By similarity)

         Genatlas biochemistry entry for MYO9A:
    unconventional myosin IXA,widely expressed,located in the BBS4 region

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003774motor activity IEA--
    GO:0003779actin binding IEA--
    GO:0005096GTPase activator activity IEA--
    GO:0005515protein binding IPI15644318
    GO:0005524ATP binding IEA--
         
    MYO9A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MYO9A:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MYO9A 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MYO9A About   (see all 9)                                                                                              See pathways by source

    SuperPathContained pathways About
    1PAK Pathway
    PAK Pathway0.56
    Epithelial Adherens Junctions0.36
    Antioxidant Action of Vitamin-C0.56
    2Actin Nucleation by ARP-WASP Complex
    Actin Nucleation by ARP-WASP Complex0.66
    RhoA Pathway0.35
    3Rho GTPase cycle
    Signaling by Rho GTPases1.00
    Rho GTPase cycle1.00
    4Fc-GammaR-Mediated Phagocytosis in Macrophages
    Fc-GammaR-Mediated Phagocytosis in Macrophages0.33
    RhoGDI Pathway0.33
    5Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYO9A (see all 11)
        RhoA Pathway
    Antioxidant Action of Vitamin-C
    Transendothelial Migration of Leukocytes
    Actin Nucleation by ARP-WASP Complex
    Epithelial Adherens Junctions

    3        Reactome Pathways for MYO9A
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    MYO9A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MYO9A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/48 Interacting proteins for MYO9A (B2RTY43 ENSP000003483494) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=3 STRING: ENSP00000367207
    PPP2R2BQ000053, ENSP000003365914I2D: score=2 STRING: ENSP00000336591
    CDC42P609533, ENSP000003144584I2D: score=5 STRING: ENSP00000314458
    MYZAPP0CAP13I2D: score=4 
    POLR2MP0CAP23I2D: score=3 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0007601visual perception TAS10409426
    GO:0035556intracellular signal transduction ----
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    MYO9A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MYO9A

    10/843 HMDB Compounds for MYO9A (see all 843)    About this table
    CompoundSynonyms CAS #PubMed Ids
    DG(14:0/14:0/0:0)DAG(14:0/14:0) (see all 9)----
    DG(14:0/14:1(9Z)/0:0)DAG(14:0/14:1) (see all 15)----
    DG(14:0/15:0/0:0)Diacylglycerol(29:0) (see all 9)----
    DG(14:0/16:0/0:0)DAG(30:0) (see all 9)----
    DG(14:0/16:1(9Z)/0:0)DG(30:1) (see all 15)----
    DG(14:0/18:0/0:0)DG(14:0/18:0) (see all 9)----
    DG(14:0/18:1(11Z)/0:0)Diacylglycerol (see all 15)----
    DG(14:0/18:1(9Z)/0:0)1-myristoyl-2-oleoyl-sn-glycerol (see all 15)----
    DG(14:0/18:2(9Z,12Z)/0:0)DAG(14:0/18:2n6) (see all 15)----
    DG(14:0/18:3(6Z,9Z,12Z)/0:0)Diacylglycerol(14:0/18:3n6) (see all 16)----

    Search CenterWatch for drugs/clinical trials and news about MYO9A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MYO9A gene: 
    NM_006901.3  

    Unigene Cluster for MYO9A:

    Myosin IXA
    Hs.546268  [show with all ESTs]
    Unigene Representative Sequence: NM_006901
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000356056(uc002atl.4) ENST00000561618 ENST00000568042 ENST00000564571
    ENST00000568481 ENST00000564699 ENST00000563071 ENST00000563542(uc002atn.1)
    ENST00000568781 ENST00000566885(uc010biq.3) ENST00000566744 ENST00000563648
    ENST00000565528 ENST00000567095 ENST00000563925 ENST00000567560(uc002ato.3)
    ENST00000568438 ENST00000569314
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    Additional mRNA sequence: 

    AB209841.1 AB290183.1 AF117888.1 AJ001714.1 AK001923.1 AK023306.1 AL137287.1 BC060886.1 
    BC140869.1 BC144683.1 BC150294.1 DQ088983.1 DQ088984.1 L29148.1 

    14 DOTS entries:

    DT.110966  DT.75198560  DT.91643477  DT.101978549  DT.100023347  DT.100786357  DT.205337  DT.40247736 
    DT.100643662  DT.121077420  DT.303809  DT.75104834  DT.75126467  DT.75146265 

    24/131 AceView cDNA sequences (see all 131):

    AW294290 AI769976 CB140040 AA287851 AI435029 AK023306 AU125900 L29148 
    BP363841 BG118393 AA235795 BM724723 BM680262 AI147845 BP348859 AI636635 
    BM724066 AK001923 AL119860 AU136653 CB120828 AI963943 AA910579 AA494302 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MYO9A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATATTCTG
    MYO9A Expression
    About this image


    See MYO9A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MYO9A

    SOURCE GeneReport for Unigene cluster: Hs.546268

    UniProtKB/Swiss-Prot: MYO9A_HUMAN, B2RTY4
    Tissue specificity: Found to be expressed in testis and placenta, and at lower levels in all the examined tissues
    with the exception of liver. Isoform 5 was found in leukocytes but not in brain, retina or testis

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO9A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MYO9A gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Myo9a1 , 5 myosin IXa1, 5 87.39(n)1
    87.9(a)1
      9 (32.13 cM)5
    2701631  NM_173018.21  NP_766606.21 
     597508965 
    chicken
    (Gallus gallus)
    Aves MYO9A6
    myosin IXA
    68(a)
    1 ↔ 1
    10(899894-1036065)
    lizard
    (Anolis carolinensis)
    Reptilia MYO9A6
    myosin IXA
    69(a)
    1 ↔ 1
    GL343479.1(402664-480750)
    zebrafish
    (Danio rerio)
    Actinopterygii myo9al11 myosin IXa-like 1 63.75(n)
    67.22(a)
      100006612  XM_001924008.3  XP_001924043.2 
    worm
    (Caenorhabditis elegans)
    Secernentea hum-71 , 3 myosin3
    Protein HUM-71
    49(a)3
    49.68(n)1
    43.06(a)1
      I(585863-607574)3
    1716501  NM_058354.21  NP_490755.11 
    rice
    (Oryza sativa)
    Liliopsida AK102087.12   -- 75.84(n)    AK102087.1 


    ENSEMBL Gene Tree for MYO9A (if available)
    TreeFam Gene Tree for MYO9A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MYO9A gene
    MYO3A2  MYO5C2  MYO102  MYO7A2  MYO9B2  MYO5A2  MYO7B2  PLEKHH32  
    MYO5B2  MYO62  MYO3B2  
    18/29 SIMAP similar genes for MYO9A using alignment to 9 protein entries:     MYO9A_HUMAN (see all proteins) (see all similar genes):
    MYO1G    MYO1B    MYO1A    ARHGAP24    MYH9    MYO1C
    MYO1D    MYO5C    MYH11    MYO9B    MYH10    ARHGAP12
    MYO10    ARHGAP5    MYO1E    PIK3R1    ARHGAP31    MYH2

    MYO9A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5215 SNPs in MYO9A are shown (see all 5215)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0461704
    ----see VAR_0461702 R Q mis40--------
    VAR_0461664
    ----see VAR_0461662 R Q mis40--------
    VAR_0461764
    ----see VAR_0461762 R C mis40--------
    VAR_0461684
    ----see VAR_0461682 N D mis40--------
    VAR_0461694
    ----see VAR_0461692 L P mis40--------
    rs611530231,2
    C--49139993(+) TTTTT-/T/TT  
            
    GAAAT
    1 -- int11NA 2
    rs340540951,2
    C--52268430(+) TTTTTT/AAATTT 1 -- int11Minor allele frequency- A:0.50NA 2
    rs30283621,2
    C--52388383(+) TTTTT-/T/TT  
            
    AAATT
    1 -- int1 trp31NA 2
    rs1918360141,2
    C--72117934(+) TAAACA/C/GGTCAC 1 -- ds50010--------
    rs1483621271,2
    C--72117943(+) CATTA-/TTTG  
            
    TTTGT
    1 -- ds50010--------

    HapMap Linkage Disequilibrium report for MYO9A (72114632 - 72364632 bp, first 250kb of MYO9A)

    Structural Variations
         Database of Genomic Variants (DGV) 10/24 variations for MYO9A (see all 24):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv821198CNV Deletion20802225
    esv2749858CNV Deletion23290073
    esv2531029CNV Deletion19546169
    esv2331045CNV Deletion18987734
    esv2749862CNV Deletion23290073
    esv2749859CNV Deletion23290073
    esv2672608CNV Deletion23128226
    esv2656527CNV Deletion23128226
    esv2749860CNV Deletion23290073
    esv2749861CNV Deletion23290073

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604875    OMIM disorders: --

    4 diseases for MYO9A:    About MalaCards
    bardet-biedl syndrome    intrahepatic cholangiocarcinoma    cholangiocarcinoma    neuronitis


    MYO9A for disorders           About GeneDecksing

    Genetic Association Database (GAD): MYO9A
    Human Genome Epidemiology (HuGE) Navigator: MYO9A (1 document)

    Export disorders for MYO9A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MYO9A gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MYO9A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23. (PubMed id 10409426)1, 2, 3, 9 Gorman S.W.... Duhl D.M. (1999)
    2. Non-EST based prediction of exon skipping and intron retention events using Pfam information. (PubMed id 16204458)1, 2 Hiller M.... Backofen R. (2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. (PubMed id 8022818)1, 2 Bement W.M....Mooseker M.S. (1994)
    5. Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. (PubMed id 23319000)1 Luykx J.J....Ophoff R.A. (2013)
    6. Myosin-IXA regulates collective epithelial cell migrat ion by targeting RhoGAP activity to cell-cell junctions. (PubMed id 22305756)1 Omelchenko T. and Hall A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Mutation of ARHGAP9 in patients with coronary spastic angina. (PubMed id 19911011)4 Takefuji M....Kaibuchi K. (2010)
    9. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    10. Hundreds of variants clustered in genomic loci and bi ological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4649 HGNC: 7608 AceView: MYO9A Ensembl:ENSG00000066933 euGenes: HUgn4649
    ECgene: MYO9A H-InvDB: MYO9A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MYO9A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MYO9A gene:
    Search GeneIP for patents involving MYO9A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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