External Ids for MYO1F Gene
Previous GeneCards Identifiers for MYO1F Gene
Myosins are molecular motors that use the energy from ATP hydrolysis to generate force on actin filaments. The protein encoded by this gene is an unconventional myosin that may be involved in the intracellular movement of membrane-enclosed compartments. There is evidence to suggest that mutations in this gene can result in hearing loss. [provided by RefSeq, Jan 2017]
GeneCards Summary for MYO1F Gene
MYO1F (Myosin IF) is a Protein Coding gene. Diseases associated with MYO1F include Deafness, Autosomal Recessive 15 and Leukemia, Acute Monocytic. Among its related pathways are PAK Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include actin binding and motor activity. An important paralog of this gene is MYO1E.
UniProtKB/Swiss-Prot for MYO1F Gene
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).