Aliases for MYO1A Gene
External Ids for MYO1A Gene
Previous HGNC Symbols for MYO1A Gene
Previous GeneCards Identifiers for MYO1A Gene
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for MYO1A Gene
MYO1A (Myosin IA) is a Protein Coding gene. Diseases associated with MYO1A include Deafness, Autosomal Dominant 48 and Autosomal Dominant Non-Syndromic Sensorineural Deafness Type Dfna. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and ERK Signaling. GO annotations related to this gene include actin binding and motor activity. An important paralog of this gene is MYO1B.
UniProtKB/Swiss-Prot for MYO1A Gene
Involved in directing the movement of organelles along actin filaments.