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MYO19 Gene

protein-coding   GIFtS: 47
GCID: GC17M034851

Myosin XIX

(Previous name: myosin head domain containing 1)
(Previous symbol: MYOHD1)
  Search for MYO19
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Myosin XIX1 2
MYOHD11 2 3
Myosin Head Domain Containing 11 2
Myosin Head Domain-Containing Protein 12 3
myosin-XIX2
Unconventional Myosin-XIX2

External Ids:    HGNC: 262341   Entrez Gene: 801792   Ensembl: ENSG000001411407   UniProtKB: Q96H553   

Export aliases for MYO19 gene to outside databases

Previous GC identifers: GC17M031926 GC17M030788


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MYO19 Gene:
MYO19 (myosin XIX) is a protein-coding gene. GO annotations related to this gene include motor activity and actin binding. An important paralog of this gene is MYO1D.

UniProtKB/Swiss-Prot: MYO19_HUMAN, Q96H55
Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in
intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which
would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NT_187614.1  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MYO19 gene promoter:
         NF-AT4   NF-AT2   NF-AT3   Nkx2-5   NF-AT1   NF-AT   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMYO19 promoter sequence
   Search Chromatin IP Primers for MYO19

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MYO19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q21.1

MYO19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYO19 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M034851:  view genomic region     (about GC identifiers)

Start:
34,851,477 bp from pter      End:
34,899,284 bp from pter
Size:
47,808 bases      Orientation:
minus strand

1 alternative location:
Chr17-,NW_003315949 380,505-420,205     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MYO19_HUMAN, Q96H55 (See protein sequence)
Recommended Name: Unconventional myosin-XIX  
Size: 970 amino acids; 109135 Da
Sequence caution: Sequence=BAD92272.1; Type=Erroneous initiation;
Secondary accessions: Q59GS4 Q9H5X2
Alternative splicing: 4 isoforms:  Q96H55-1   Q96H55-2   Q96H55-3   Q96H55-4   

Explore the universe of human proteins at neXtProt for MYO19: NX_Q96H55

Explore proteomics data for MYO19 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MYO19 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001028752.1  NP_001157207.1  NP_079385.2  

    ENSEMBL proteins: 
     ENSP00000409936   ENSP00000468792   ENSP00000468488   ENSP00000268852   ENSP00000467845  
     ENSP00000468228   ENSP00000466786   ENSP00000438365   ENSP00000465350   ENSP00000467285  
     ENSP00000466713   ENSP00000467683  

    MYO19 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MYO19

    MYO19 Antibody Products:

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    MYO19 Assay Products:

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    Cloud-Clone Corp. CLIAs for MYO19


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MYOXIX: Myosins / Myosin superfamily : Class XIX

    3 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000048 IQ_motif_EF-hand-BS
     IPR001609 Myosin_head_motor_dom

    Graphical View of Domain Structure for InterPro Entry Q96H55

    ProtoNet protein and cluster: Q96H55

    1 Blocks protein domain: IPB000048 IQ calmodulin-binding region

    UniProtKB/Swiss-Prot: MYO19_HUMAN, Q96H55
    Similarity: Contains 2 IQ domains
    Similarity: Contains 1 myosin head-like domain


    MYO19 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MYO19_HUMAN, Q96H55
    Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in
    intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which
    would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003774motor activity IEA--
    GO:0003779actin binding IEA--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
         
    MYO19 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MYO19:
     Decreased cilium length after   Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MYO19
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MYO19

    miRNA
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    miRTarBase miRNAs that target MYO19:
    hsa-mir-93-5p (MIRT028110), hsa-mir-186-5p (MIRT045295), hsa-mir-124-3p (MIRT023003), hsa-mir-16-5p (MIRT051272), hsa-mir-92a-3p (MIRT049142), hsa-mir-615-3p (MIRT039861), hsa-mir-505-3p (MIRT041011), hsa-mir-125b-5p (MIRT045930)

    Block miRNA regulation of human, mouse, rat MYO19 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MYO19 (see all 12):
    hsa-miR-31 hsa-miR-328 hsa-miR-1271 hsa-miR-1291 hsa-miR-511 hsa-miR-124 hsa-miR-182 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidMYO19 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MYO19

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    GenScript: all cDNA clones in your preferred vector (see all 3): MYO19 (NM_001033580)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYO19

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO19


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MYO19_HUMAN, Q96H55: Cytoplasm, cytoskeleton. Mitochondrion outer membrane. Note=Probably associated with the
    outer membrane via its N-terminal mitochondrial targeting region
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    mitochondrion5
    cytosol3
    nucleus2
    golgi apparatus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005741mitochondrial outer membrane IEA--
    GO:0016459myosin complex IEA--

    MYO19 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MYO19
    Interactions:

        Search GeneGlobe Interaction Network for MYO19

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MYO19



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MYO19 gene (4 alternative transcripts): 
    NM_001033579.1  NM_001033580.2  NM_001163735.1  NM_025109.5  

    Unigene Cluster for MYO19:

    Myosin XIX
    Hs.302051  [show with all ESTs]
    Unigene Representative Sequence: NM_001163735
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000431794(uc010cuu.3 uc010wcy.2 uc010wcz.1) ENST00000586908
    ENST00000591794 ENST00000588377 ENST00000268852(uc002hmw.3 uc010wda.1 uc002hmx.2)
    ENST00000593275 ENST00000592110 ENST00000590233 ENST00000586328 ENST00000593222
    ENST00000591477 ENST00000592735 ENST00000588727 ENST00000588471 ENST00000591017
    ENST00000587389 ENST00000590585 ENST00000586007
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MYO19 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MYO19 (see all 12):
    hsa-miR-31 hsa-miR-328 hsa-miR-1271 hsa-miR-1291 hsa-miR-511 hsa-miR-124 hsa-miR-182 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidMYO19 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MYO19
    Predesigned siRNA for gene silencing in human, mouse, rat MYO19
    Clone
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    OriGene ORF clones in mouse, rat for MYO19
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): MYO19 (NM_001033580)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYO19
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYO19
    Primer
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    OriGene qPCR primer pairs and template standards for MYO19
    OriGene qSTAR qPCR primer pairs in human, mouse for MYO19
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MYO19
      QuantiTect SYBR Green Assays in human, mouse, rat MYO19
      QuantiFast Probe-based Assays in human, mouse, rat MYO19

    Additional mRNA sequence: 

    AK026518.1 AK293903.1 AK299802.1 AK304073.1 AL049275.1 AL133017.1 AY545559.1 BC008900.2 
    BC036325.1 BC041980.1 

    Selected DOTS entries (see all 30):

    DT.423511  DT.95373367  DT.95373374  DT.99976135  DT.91941231  DT.95373356  DT.100826435  DT.121643737 
    DT.92426495  DT.40298847  DT.121002684  DT.91729248  DT.121002667  DT.92426497  DT.100020445  DT.91938169 
    DT.446418  DT.100031461  DT.419655  DT.91755398  DT.91910903  DT.92038196  DT.100837437  DT.408274 

    Selected AceView cDNA sequences (see all 162):

    BF968765 BM666622 AI378368 CB159365 AI168838 BU509222 AW005609 BX280258 
    BX457543 BU543266 BQ181670 BQ650642 AL525887 BQ050997 BU196917 BP358072 
    AI867088 AA812539 AI968790 AA161002 BU527354 BQ063197 BQ182953 AW005600 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MYO19 (see all 32)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ·
    SP1:                                      -     -     -     -                 -     -     -                 -                 -                                 
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                  -     -                 -     -     -                 -                 -                                 
    SP5:                                                                                                                                                            

    ExUns: 9c ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b ^ 16a · 16b · 16c ^ 17a · 17b · 17c ^ 18a · 18b ^ 19a · 19b · 19c ^ 20a · 20b · 20c ·
    SP1:                                                                                                                                                            
    SP2:                                                                                      -                             -                       -               
    SP3:                                                  -     -     -     -                 -                                                                     
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 20d · 20e ^ 21a · 21b ^ 22a · 22b · 22c ^ 23a · 23b ^ 24a · 24b · 24c ^ 25a · 25b · 25c ^ 26a · 26b · 26c ^ 27a · 27b ^ 28a · 28b ^ 29 ^ 30a · 30b
    SP1:                                                                                                                                                      
    SP2:                                                                                                                                                      
    SP3:                                                                                                                                                      
    SP4:                                                                                                                                                      
    SP5:                                                        -     -                       -     -                             -                           


    ECgene alternative splicing isoforms for MYO19

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MYO19 expression in normal human tissues (normalized intensities)      MYO19 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MYO19 Expression
    About this image


    MYO19 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Bone (Muscoskeletal System)
             Rib
     
     Cartilage (Muscoskeletal System)
             Meckel's Cartilage
    MYO19 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MYO19 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.302051

    UniProtKB/Swiss-Prot: MYO19_HUMAN, Q96H55
    Tissue specificity: Widely expressed in multiple tissues and cell lines

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO19

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MYO19 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Myo191 , 5 myosin XIX1, 5 83.39(n)1
    82.41(a)1
      11 (51.34 cM)5
    661961  NM_025414.31  NP_079690.21 
     848801485 
    chicken
    (Gallus gallus)
    Aves MYO191 myosin XIX 62.94(n)
    61.12(a)
      417649  XM_415895.4  XP_415895.4 
    lizard
    (Anolis carolinensis)
    Reptilia MYO196
    myosin XIX
    57(a)
    1 ↔ 1
    GL344386.1(1643-31217)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia myo191 myosin XIX 60.54(n)
    59.83(a)
      734140  NM_001128645.1  NP_001122117.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5622791 unconventional myosin-XIX-like 58.11(n)
    52.82(a)
      562279  XM_001920048.4  XP_001920083.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG401556
    --
    35(a)
    1 ↔ 1
    3RHet(1042-92187)


    ENSEMBL Gene Tree for MYO19 (if available)
    TreeFam Gene Tree for MYO19 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MYO19 gene
    MYO1D2  MYO15A2  MYO1C2  MYO1A2  MYO1F2  MYO1G2  MYO1B2  MYO15B2  
    MYO1E2  MYO1H2  
    Selected SIMAP similar genes for MYO19 using alignment to 11 protein entries:     MYO19_HUMAN (see all proteins) (see all similar genes):
    MYH7B    MYO3B    MYO1A    MYO1C    MYO1B    MYO1E
    MYO9B    MYH2    MYO6    MYO5C    MYO1G    MYO5B
    MYH14    MYO10    MYO9A    MYO1D    MYO7B    MYO5A

    MYO19 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MYO19 (see all 1084)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2008726071,2
    --30787914(+) GCTCAA/GTCCAC 2 -- int10--------
    rs1504950581,2
    C--30787930(+) AGGCAG/ATTGAT 2 -- int11Minor allele frequency- A:0.00NA 4550
    rs1471783281,2
    C--30787945(+) AACCTC/GGATCA 2 -- int10--------
    rs115426171,2
    H--30787959(+) AGAAGA/GCAAAG 2 -- int14Minor allele frequency- G:0.00NS EA 404
    rs1913517421,2
    C--30787962(+) AGACAA/GAGCAA 2 -- int10--------
    rs1113096281,2
    C,F--30787972(+) AAGCTA/C/TATGAG 2 -- int12CSA EU 1325
    rs2014552731,2
    C--30788033(+) GAATTA/C/GTGGAG 2 -- int11EU 1323
    rs1998345031,2
    --30788051(+) AGAATA/GAGGAG 2 -- int10--------
    rs1386469111,2
    C--30788066(+) AAGATA/GGATTA 2 -- int10--------
    rs1177676181,2
    C--30788072(+) GATTAT/CTGTGC 2 -- int12Minor allele frequency- C:0.00EA EU 1437

    HapMap Linkage Disequilibrium report for MYO19 (34851477 - 34899284 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MYO19 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv469760CNV Loss16826518
    dgv122e55CNV Gain17911159
    nsv526727CNV Gain19592680
    nsv428340CNV Gain18775914
    nsv469796CNV Gain16826518
    esv2751645CNV Gain17911159
    nsv471697CNV Gain15918152
    nsv457734CNV Gain19166990
    nsv516100CNV Gain+Loss19592680
    essv6619CNV CNV17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MYO19
    DNA2.0 Custom Variant and Variant Library Synthesis for MYO19

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MYO19 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with MYO19)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Myo19 is a novel myosin that associates with mitochondria. (PubMed id 19932026)1, 2, 3 Quintero O.A....Cheney R.E. (Curr. Biol. 2009)
    2. Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species. (PubMed id 17877792)1, 3 Odronitz F. and Kollmar M. (Genome Biol. 2007)
    3. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80179 HGNC: 26234 AceView: MYOHD1 Ensembl:ENSG00000141140 euGenes: HUgn80179
    ECgene: MYO19 H-InvDB: MYO19

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MYO19 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MYO19 gene:
    Search GeneIP for patents involving MYO19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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