Aliases for MYO18B Gene
External Ids for MYO18B Gene
Previous GeneCards Identifiers for MYO18B Gene
The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYO18B Gene
MYO18B (Myosin XVIIIB) is a Protein Coding gene. Diseases associated with MYO18B include lung cancer. Among its related pathways are RhoGDI Pathway and ERK Signaling. GO annotations related to this gene include actin binding and motor activity. An important paralog of this gene is MYO18A.
UniProtKB/Swiss-Prot for MYO18B Gene
May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth