MYO18B Gene
protein-coding GIFtS: 51
GCID: GC22P026138
|
|
myosin XVIIIB
| |
Aliases
for MYO18B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myosin XVIIIB1 2 | | BK125H2.11 | | Myosin 18B2 | | Myosin-XVIIIb1 | | Unconventional Myosin-XVIIIb2 |
Export aliases for MYO18B gene to outside databasesPrevious GC identifers: GC22P022834 GC22P024462 GC22P009085 |
Summaries
for MYO18B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MYO18B:
The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellulartrafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin.Mutations in this gene are associated with lung cancer. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MY18B_HUMAN, Q8IUG5Function: May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering thenucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumordevelopment and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth
Gene Wiki entry for MYO18B
|
Genomic Views
for MYO18B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MYO18B gene promoter:
c-Fos AP-1 AML1a p300 AP-4 SRY FOXO4 SEF-1 (1) c-Jun RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for MYO18B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYO18B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q12.1 Ensembl cytogenetic band: 22q12.1 HGNC cytogenetic band: 22q12.1MYO18B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P026138: view genomic region
(about GC identifiers)
Start:
|
26,138,111 bp from pter |
End:
|
26,427,007 bp from pter |
Size:
|
288,897 bases |
Orientation:
|
plus strand |
|
Proteins
for MYO18B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MY18B_HUMAN, Q8IUG5 (See
protein sequence)Recommended Name: Unconventional myosin-XVIIIb Size: 2567 amino acids; 285185 Da
Subunit: Homodimer. May interact with F actin through the GPA motif (Gly/Pro/Ala-rich)
Subcellular location: Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiatedmyoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in somecardiomyocytes
Developmental stage: Reaches an expression peak in the third day after induction and remains at similar level duringsuccessive myotubule maturation
Miscellaneous: Frequently deleted, mutated, and hypermethylated in lung cancers
Secondary accessions: B2RWP3 F5GYU7 Q8NDI8 Q8TE65 Q8WWS0 Q96KH2 Q96KR8 Q96KR9Alternative splicing: 2 isoforms: Q8IUG5-1 Q8IUG5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MYO18B: NX_Q8IUG5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IUG5
MYO18B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115997.5
ENSEMBL proteins: ENSP00000441229 ENSP00000334563 ENSP00000386096 ENSP00000437587 ENSP00000444262 ENSP00000441301
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
MYO18B for ontologies About GeneDecksing
MYO18B Antibody Products:
Assay Products for MYO18B: |
Protein
Domains /
Families
for MYO18B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MYO18B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IUG5ProtoNet protein and cluster: Q8IUG5 UniProtKB/Swiss-Prot: MY18B_HUMAN, Q8IUG5Similarity: Contains 1 IQ domainSimilarity: Contains 1 myosin head-like domain |
Function
for MYO18B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MY18B_HUMAN, Q8IUG5Function: May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering thenucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumordevelopment and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYO18B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYO18B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MYO18B (NM_032608) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYO18B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MYO18B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO18B |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
MYO18B for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MYO18B:
Animal Models:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Myo18b):
MYO18B for phenotypes About GeneDecksing
|
Pathways & Interactions
for MYO18B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | PAK Pathway | | | 2 | Fc-GammaR-Mediated Phagocytosis in Macrophages | | | 3 | Actin Nucleation by ARP-WASP Complex | | | 4 | Sweet Taste Signaling | | | 5 | Rho Family GTPases | |
5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYO18B (see all 11)
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MYO18B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/11 Interacting proteins for MYO18B (Q8IUG53 ENSP000003860964) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001570 | vasculogenesis |
-- | -- | | GO:0001701 | in utero embryonic development |
-- | -- | | GO:0048739 | cardiac muscle fiber development |
-- | -- |
MYO18B for ontologies About GeneDecksing
|
Drugs & Compounds
for MYO18B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MYO18B for compounds About GeneDecksing
 Browse Tocris compounds for MYO18B
1 Novoseek chemical compound relationship for MYO18B gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 5-aza-2'deoxycytidine |
72.3 |
6 |
15751041 (1), 12209013 (1), 15305387 (1) |
Search CenterWatch for drugs/clinical trials and news about MYO18B / MY18B
|
Transcripts
for MYO18B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MYO18B gene: NM_032608.5 Unigene Cluster for MYO18B: Myosin XVIIIB Hs.417959 [show with all ESTs]Unigene Representative Sequence: NM_03260810 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000536101(uc003aca.1) ENST00000335473(uc003abz.1 uc010guy.1 uc010guz.1 uc011aka.1 uc010gva.1 uc010gvb.1)
ENST00000407587 ENST00000539302 ENST00000418374(uc011akb.1) ENST00000534908
ENST00000536204 ENST00000539544 ENST00000543971 ENST00000540454
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYO18B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYO18B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MYO18B (NM_032608) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYO18B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MYO18B |
Additional cDNA sequence: AB042648.2 AB075376.1 AJ271918.1 AJ310931.2 AK095943.1 AK123936.1 AL833890.1 AY077700.1 BC144596.1 BC144597.1 BC150626.1 CR749556.1 11 DOTS entries: DT.431242 DT.99932561 DT.40258444 DT.101981467 DT.100750227 DT.100018555 DT.120675171 DT.75145738 DT.100655097 DT.120675199 DT.91819346 24/42 AceView cDNA sequences (see all 42): BM722939 BX646937 NM_032608 AL833890 AK095943 AJ310931 H55541 H55072 AB042648 F36455 AY077700 AB075376 BQ931968 BG113122 F21473 AA346829 CR749556 AK123936 BX502365 BG723415 F27546 BM677404 AJ271918 CF551892
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MYO18B (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32a | · | 32b | · | 32c | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40a | · | 40b | ^ | 41 | ^ | 42 | ^ | 43 | ^ | 44a | · | 44b | ^ | 45a | · |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | |
ECgene alternative splicing isoforms for MYO18B
|
Expression
for MYO18B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MYO18B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCACCCTCA
About this image
See MYO18B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYO18B
SOURCE GeneReport for Unigene cluster: Hs.417959
UniProtKB/Swiss-Prot: MY18B_HUMAN, Q8IUG5Tissue specificity: Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas,placenta, prostate, lung and thymus
SABiosciences Custom PCR Arrays for MYO18B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYO18B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYO18B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYO18B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYO18B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO18B |
Orthologs
for MYO18B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MYO18B gene from 4/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MYO18B1 |
myosin XVIIIB |
62.27(n)
55.02(a) |
|
416905 XM_415196.3 XP_415196.3 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
BX684488.12 |
-- |
75.27(n) |
|
BX684488.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
CABZ01085662.16CABZ01073112.16 |
-- |
40(a)34(a) |
possible ortholog1 ↔ 1 |
10(45725935-45746157) 10(45967086-45994332) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Mhcl6 |
Myosin heavy chain-like |
24(a) |
1 → many |
3R(11894245-11924483) |
ENSEMBL Gene Tree for MYO18B (if available)
TreeFam Gene Tree for MYO18B (if available) |
Paralogs
for MYO18B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MYO18B gene
- MYO18A2
7 SIMAP similar genes for MYO18B using alignment to 5 protein entries: MY18B_HUMAN (see all proteins):DKFZp779C1668 MYO18A MYH9 MAJN MYO1B MYH10
MYH11
MYO18B for paralogs About GeneDecksing
|
Genomic Variants
for MYO18B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MYO18B (26138111 - 26388111 bp, first 250kb of MYO18B)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for MYO18B
2 CNVs: 8904 3240
1 Indel: 103145
Human Gene Mutation Database (HGMD): MYO18B
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYO18B |
|
Disorders
/ Diseases
for MYO18B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MYO18B for disorders About GeneDecksing
OMIM gene information: 607295
OMIM disorders: --
7  diseases for MYO18B: About MalaCardslung cancer malignant pleural mesothelioma bipolar disorder ovarian cancer
colorectal cancer schizophrenia prostatitis
2 Novoseek disease relationships for MYO18B gene About this table
Human Genome Epidemiology (HuGE) Navigator: MYO18B (2 documents)
Export disorders for MYO18B gene to outside databases
|
Publications
for MYO18B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MYO18B gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with MYO18B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer. (PubMed id 12209013)1, 2, 3, 9 Nishioka M.... Yokota J. (2002)
- Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation. (PubMed id 12547197)1, 2, 3, 9 Salamon M....Lanfranchi G. (2003)
- Genetic alterations responsible for metastatic phenotypes of lung cancer cells. (PubMed id 12741677)1, 2, 9 Yokota J.... Kohno T. (2003)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. (PubMed id 15305387)1, 9 Yanaihara N....Yokota J. (2004)
- Restored expression of the MYO18B gene suppresses orthotopic growth and the production of bloody pleural effusion by human malignant pleural mesothelioma cells in SCID mice. (PubMed id 17294804)1, 9 Edakuni N....Sone S. (2006)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A genome-wide association study of serum uric acid in African Americans. (PubMed id 21294900)1 Charles B.A....Rotimi C.N. (2011)
- Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. (PubMed id 20713499)1 Huang J....Smoller J.W. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
|
External Searches for MYO18B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MYO18B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MYO18B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MYO18B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MYO18B gene:
Search GeneIP for patents involving MYO18B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MYO18B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MYO18B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYO18B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYO18B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MYO18B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYO18B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYO18B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MYO18B | | OriGene Custom Protein Services for MYO18B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MYO18B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYO18B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYO18B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYO18B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYO18B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYO18B |
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| | | | Search Tocris compounds for MYO18B |
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 | | | MYO18B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO18B |
|  |  |  | | | | Search ThermoFisher Antibodies for MYO18B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MYO18B |
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