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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MYO18A Gene

protein-coding GIFtS: 53
GCID: GC17M027400

myosin XVIIIA

Explore 8 diseases affiliated with
MYO18A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Myosin XVIIIA¹ ²		MysPDZ¹
KIAA0216¹ ³		Myosin 18A²
Molecule Associated With JAK3 N-Terminus² ³		Myosin Containing PDZ Domain²
Myosin Containing A PDZ Domain² ³		Myosin-XVIIIa¹
MAJN² ³		SP-A Receptor Subunit SP-R210 AlphaS²
MYSPDZ² ³		Unconventional Myosin-XVIIIa²
SPR210² ⁵

External Ids:	HGNC: 31104¹	Entrez Gene: 399687²	Ensembl: ENSG00000196535⁷	OMIM: 610067⁵	UniProtKB: Q92614³

Export aliases for MYO18A gene to outside databases

Previous GC identifers: GC17M027547 GC17M024425 GC17M023608

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MY18A_HUMAN, Q92614

Function: May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By

similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde

flow that is crucial to cell protrusion and migration

Gene Wiki entry for MYO18A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010799.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MYO18A gene promoter:
Spz1 Pax-5 Sp1 SREBP-1c MyoD Nkx5-1 SREBP-1b FAC1 SREBP-1a Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): MYO18A promoter sequence

Search SABiosciences Chromatin IP Primers for MYO18A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYO18A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2 Ensembl cytogenetic band: 17q11.2 HGNC cytogenetic band: 17q11.2

MYO18A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYO18A gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M027400: view genomic region (about GC identifiers)

Start:	27,400,528 bp from pter	End:	27,507,430 bp from pter
Size:	106,903 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MY18A_HUMAN, Q92614 (See protein sequence)

Recommended Name: Unconventional myosin-XVIIIa

Size: 2054 amino acids; 233115 Da

Subunit: Homodimer. Interacts with JAK3 and actin. Forms a tripartite complex with CDC42BPA/CDC42BPB and LURAP1 with

the latter acting as an adapter connecting CDC42BPA/CDC42BPB and MYO18A

Subcellular location: Isoform 1: Endoplasmic reticulum-Golgi intermediate compartment (By similarity). Cytoplasm,

cytoskeleton. Note=Colocalizes with actin

Subcellular location: Isoform 2: Cytoplasm. Note=Lacks the PDZ domain. Diffusely localized in the cytoplasm

Caution: The TIAF1 protein is coded in the 3'-UTR region of MYO18A

Sequence caution: Sequence=BAA13206.2; Type=Erroneous initiation; Sequence=BAD66838.1; Type=Erroneous initiation;

Secondary accessions: Q5H9U3 Q5W9F9 Q5W9G1 Q8IXP8

Alternative splicing: 5 isoforms: Q92614-1 Q92614-2 Q92614-3 Q92614-4 Q92614-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MYO18A: NX_Q92614

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q92614

MYO18A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_510880.2 NP_976063.1

ENSEMBL proteins:

ENSP00000435932 ENSP00000434228 ENSP00000437073 ENSP00000434817 ENSP00000465542

ENSP00000436660 ENSP00000346291

Reactome Protein details: Q92614
Human Recombinant Protein Products:

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	GenScript Custom Purified and Recombinant Proteins Services for MYO18A
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MYO18A

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IEA	--
GO:0005856	cytoskeleton	--	--
GO:0016459	myosin complex	IEA	--
GO:0042641	actomyosin	IDA	18854160

MYO18A for ontologies About GeneDecksing

MYO18A Antibody Products:

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	Uscn ELISAs and CLIAs for MYO18A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MYO18A for domains About GeneDecksing

5 InterPro domains/families:

IPR001478 PDZ

IPR000048 IQ_motif_EF-hand-BS

IPR002928 Myosin_tail

IPR001609 Myosin_head_motor_dom

IPR020587 RecA_monomer-monomer_interface

Graphical View of Domain Structure for InterPro Entry Q92614

ProtoNet protein and cluster: Q92614

2 Blocks protein families:

IPB000048 IQ calmodulin-binding region

IPB003345 M protein repeat

UniProtKB/Swiss-Prot: MY18A_HUMAN, Q92614

Similarity: Contains 1 IQ domain

Similarity: Contains 1 myosin head-like domain

Similarity: Contains 1 PDZ (DHR) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MY18A_HUMAN, Q92614

Function: May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By

similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde

flow that is crucial to cell protrusion and migration

miRNA Products:		OriGene 3'-UTR Clone (see all 2): MYO18A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYO18A
		8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate MYO18A (see all 24):
		hsa-miR-125a-5p hsa-miR-331-3p hsa-miR-3154 hsa-miR-125b hsa-miR-3649 hsa-miR-3174 hsa-miR-761 hsa-miR-635

		SwitchGear 3'UTR luciferase reporter plasmid: MYO18A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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		Search LifeMap BioReagents cell lines for MYO18A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYO18A

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003774	motor activity	IEA	--
GO:0005515	protein binding	IPI	19837035
GO:0005524	ATP binding	IEA	--
GO:0008094	DNA-dependent ATPase activity	IEA	--

MYO18A for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Signaling by FGFR1 mutants

	Signaling by FGFR1 mutants	1.00			Signaling by FGFR1 fusion mutants	0.63
	Signaling by FGFR mutants	0.67			FGFR1 fusion proteins recruit PIK3R1	0.37

Disease

Disease

1.00

Signaling by FGFR

Signaling by FGFR in disease

0.91

Pathway sources
See GeneCards unified pathways
Show all pathways

5/6 Reactome Pathways for MYO18A (see all 6)

	Signaling by FGFR mutants
	Signaling by FGFR1 fusion mutants
	Signaling by FGFR in disease
	Signaling by FGFR1 mutants
	Disease

MYO18A for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MYO18A

STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

5/16 Interacting proteins for MYO18A (Q92614^{1, 3} ENSP00000346291⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 16)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GOLPH3	Q9H4A6¹^,³, ENSP00000265070⁴	EBI-949059,EBI-2465479 I2D: score=1 STRING: ENSP00000265070
ATXN1	P54253³, ENSP00000244769⁴	I2D: score=2 STRING: ENSP00000244769
MARK4	Q96L34³, ENSP00000300843⁴	I2D: score=2 STRING: ENSP00000300843
CDC42BPA	Q5VT25³, ENSP00000355731⁴	I2D: score=1 STRING: ENSP00000355731
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006259	DNA metabolic process	IEA	--
GO:0016477	cell migration	IMP	18854160
GO:0031032	actomyosin structure organization	IMP	18854160
GO:0043066	negative regulation of apoptotic process	TAS	9918798

MYO18A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

MYO18A for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MYO18A
1 Novoseek chemical compound relationship for MYO18A gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine	25.1	4	14969583 (2)

Search CenterWatch for drugs/clinical trials and news about MYO18A / MY18A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MYO18A gene (2 alternative transcripts):

NM_078471.3 NM_203318.1

Unigene Cluster for MYO18A:

Myosin XVIIIA

Hs.462590 [show with all ESTs]

Unigene Representative Sequence: D86970

18/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):

ENST00000529578 ENST00000533112(uc010csa.1) ENST00000531253(uc010wbc.1)

ENST00000527372(uc002hdt.1 uc002hdu.1) ENST00000530254(uc002hds.2 uc010wbd.1)

ENST00000546105 ENST00000532867 ENST00000527312 ENST00000531438 ENST00000531892

ENST00000529889 ENST00000530557 ENST00000533652 ENST00000532143 ENST00000533399

ENST00000588791 ENST00000590242 ENST00000528564

miRNA Products:		OriGene 3'-UTR Clone (see all 2): MYO18A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYO18A
		8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate MYO18A (see all 24):
		hsa-miR-125a-5p hsa-miR-331-3p hsa-miR-3154 hsa-miR-125b hsa-miR-3649 hsa-miR-3174 hsa-miR-761 hsa-miR-635

		SwitchGear 3'UTR luciferase reporter plasmid: MYO18A 3' UTR sequence

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYO18A

Additional cDNA sequence:

AB177858.1 AB177860.1 AF105277.1 AF252258.1 AK294180.1 AK302505.1 AK302725.1 AK303522.1

AY703984.1 BC039612.1 BC047669.1 BC058075.1 BC131561.1 BC131586.1 CR933614.1 D86970.2

24/25 DOTS entries (see all 25):

DT.102833620 DT.100029510 DT.100818688 DT.447608 DT.100818687 DT.95225182 DT.100029511 DT.100801802

DT.91676723 DT.120988031 DT.86854815 DT.100818685 DT.100818691 DT.75146885 DT.120987899 DT.120987943

DT.120988018 DT.91846798 DT.92442605 DT.92442606 DT.92442610 DT.95225183 DT.97846576 DT.91980304

24/311 AceView cDNA sequences (see all 311):

AJ571771 CA448626 AW576350 BP345876 CB268076 NM_004740 BU191933 CA448050

F31497 NM_078471 AK122870 BQ644444 CD674438 BQ058479 BM978373 CD675379

AA952885 AL046057 BI092916 AA372000 AW778911 BQ962332 BQ447907 AI015823

GeneLoc Exon Structure

5/18 Alternative Splicing Database (ASD) splice patterns (SP) for MYO18A (see all 18) About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14a	·	14b	^	15a	·	15b	·	15c	^	16a	·	16b	·	16c	·	16d	^	17a	·
SP1:			-				-		-		-		-		-		-		-		-		-		-		-		-
SP2:																	-		-		-		-		-		-		-
SP3:							-		-		-		-		-		-		-		-		-		-		-		-
SP4:
SP5:													-		-		-		-		-		-		-		-		-						-		-

ExUns:	17b	·	17c	^	18	^	19	^	20	^	21	^	22	^	23	^	24a	·	24b	^	25a	·	25b	^	26	^	27	^	28	^	29a	·	29b	^	30	^	31	^	32	^	33a	·	33b	^	34	^	35	^	36	^	37a	·
SP1:																	-														-																				-
SP2:																	-														-																				-
SP3:																	-														-																				-
SP4:
SP5:

ExUns:	37b	^	38	^	39	^	40	^	41	^	42	^	43	^	44	^	45a	·	45b	^	46	^	47	^	48a	·	48b	^	49a	·	49b	^	50a	·	50b	·	50c	·	50d	^	51	^	52	^	53a	·	53b	·	53c
SP1:															-		-		-						-								-		-
SP2:															-		-		-						-								-		-						-
SP3:							-								-		-		-						-								-		-						-
SP4:																									-								-		-						-
SP5:

ECgene alternative splicing isoforms for MYO18A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MYO18A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
See MYO18A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYO18A

SOURCE GeneReport for Unigene cluster: Hs.462590

SABiosciences Expression via Pathway-Focused PCR Array including MYO18A:

Apoptosis 384HT in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MYO18A gene from 4/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MYO18A¹	myosin XVIIIA	80.75(n) 84.9(a)		417581 XM_415827.3 XP_415827.3
lizard (Anolis carolinensis)	Reptilia	MYO18A⁶	--	81(a)	1 ↔ 1	GL343462.1(126090-244323)
zebrafish (Danio rerio)	Actinopterygii	myo18ab⁶ myo18aa⁶ (see all 3)	myosin XVIIIAa (see all 3)	77(a) 59(a) (see all 3)	1 ↔ many 1 ↔ many (see all 3)	15(23305108-23469164) 10(38273747-38406003)
fruit fly (Drosophila melanogaster)	Insecta	Mhcl¹	Myosin heavy chain-like	52.13(n) 43.06(a)		41955 NM_001043250.2 NP_001036715.1

ENSEMBL Gene Tree for MYO18A (if available)
TreeFam Gene Tree for MYO18A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MYO18A gene

MYO18B²

13 SIMAP similar genes for MYO18A using alignment to 6 protein entries: MY18A_HUMAN (see all proteins):

MAJN MYH7 MYO18B MYH10 MYH11 MYH14

MYO1E MYH9 MYO1B MYH2 MYO10 MYO1A

MYO5C

MYO18A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs189408746^1,2		--	27404658(+)	`CCAATC/TCTCCT`	2	--	int¹		0	--	--	--	--
rs73268313^1,2	C,	--	27404670(+)	`GGAGCG/AGGTGG`	2	--	int¹		2		WA	120
rs141841115^1,2		--	27404704(+)	`CAGCTC/TTCCTG`	2	--	int¹		0	--	--	--	--
rs80326352^1,2	C,F,	--	27404749(+)	`AGAAAC/TAGGCT`	2	--	int¹		1		WA	118
rs145584174^1,2		--	27404939(+)	`TCTCCA/CAGGTC`	2	--	int¹		0	--	--	--	--
rs8075134^1,2	C,F,A,H,	--	27404953(+)	`CAGCTA/GACTTC`	2	--	int¹		21		NS EA NA WA CSA	2344
rs8080453^1,2	C,F,A,H,	--	27405044(+)	`TATATT/ATTTTT`	2	--	int¹		4		WA NA CSA	8
rs201211034^1,2		--	27405044(+)	`TATAT-/ATTTTT`	2	--	int¹		0	--	--	--	--
rs8065952^1,2	C,F,A,H,	--	27405050(+)	`TTTTTT/CGAGAT`	2	--	int¹		4		NA WA CSA	126
rs147725256^1,2		--	27405101(+)	`GATCTC/TGGTTC`	2	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MYO18A (27400528 - 27507430 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MYO18A: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MYO18A for disorders           About GeneDecksing

OMIM gene information: 610067    OMIM disorders: --

8 diseases for MYO18A:    About MalaCards

vesicoureteral reflux stem cell leukemia eosinophilia t-cell leukemia

ataxia tuberculosis leukemia mycobacterium tuberculosis

Human Genome Epidemiology (HuGE) Navigator: MYO18A (1 document)

Export disorders for MYO18A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MYO18A gene, integrated from 9 sources (see all 39):
(articles sorted by number of sources associating them with MYO18A)

Utopia: connect your pdf to the dynamic
world of online information

Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A). (PubMed id 12761286)^{1, 2, 3} Mori K.... Obinata M. (2003)
The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site. (PubMed id 15835906)^{1, 2, 9} Isogawa Y....Sutoh K. (2005)
A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow. (PubMed id 18854160)^{1, 2} Tan I....Leung T. (2008)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Alternative splice variants encoding unstable protein domains exist in the human brain. (PubMed id 15491607)^{1, 2} Homma K.... Nishikawa K. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival. (PubMed id 10733938)^{1, 2} Ji H.... Zheng Z. (2000)
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{1, 2} Nagase T....Nomura N. (1996)
Proteomics analysis of the ezrin interactome in B cell s reveals a novel association with Myo18aa. (PubMed id 21751808)¹ Matsui K....Gupta N. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 399687	HGNC: 31104	AceView: TIAF1	Ensembl:ENSG00000196535	euGenes: HUgn399687
ECgene: MYO18A	H-InvDB: MYO18A

(According to HUGE)
About This Section

HUGE: KIAA0216

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MYO18A	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for MYO18A	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for MYO18A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MYO18A gene:
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