Aliases for MYO18A Gene
External Ids for MYO18A Gene
Previous GeneCards Identifiers for MYO18A Gene
GeneCards Summary for MYO18A Gene
MYO18A (Myosin XVIIIA) is a Protein Coding gene. Diseases associated with MYO18A include 8p11 myeloproliferative syndrome. Among its related pathways are Signaling by FGFR1 in disease and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include poly(A) RNA binding and actin filament binding. An important paralog of this gene is MYO18B.
UniProtKB/Swiss-Prot for MYO18A Gene
May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.