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Aliases for MYO15B Gene

Aliases for MYO15B Gene

  • Myosin XVB 2 3 5
  • Myosin XVB Pseudogene 2 3
  • MYO15BP 3 4
  • Unconventional Myosin XVBP Pseudogene 3
  • Unconventional Myosin-15B 4
  • Myosin XVBP 4
  • KIAA1783 4

External Ids for MYO15B Gene

Previous GeneCards Identifiers for MYO15B Gene

  • GC17P073562
  • GC17P076610
  • GC17P074048
  • GC17P074182
  • GC17P074214
  • GC17P071096
  • GC17P069007
  • GC17P073586

Summaries for MYO15B Gene

GeneCards Summary for MYO15B Gene

MYO15B (Myosin XVB) is a Protein Coding gene. An important paralog of this gene is MYO15A.

UniProtKB/Swiss-Prot for MYO15B Gene

  • Unknown, due to the absence of a functional motor domain.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYO15B Gene

Genomics for MYO15B Gene

Regulatory Elements for MYO15B Gene

Enhancers for MYO15B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MYO15B on UCSC Golden Path with GeneCards custom track

Promoters for MYO15B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MYO15B Gene

75,588,058 bp from pter
75,626,849 bp from pter
38,792 bases
Plus strand

Genomic View for MYO15B Gene

Genes around MYO15B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MYO15B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MYO15B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYO15B Gene

Proteins for MYO15B Gene

  • Protein details for MYO15B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Unconventional myosin-XVB
    Protein Accession:

    Protein attributes for MYO15B Gene

    1530 amino acids
    Molecular mass:
    167118 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB47412.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for MYO15B Gene

neXtProt entry for MYO15B Gene

Post-translational modifications for MYO15B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MYO15B Gene

Domains & Families for MYO15B Gene

Gene Families for MYO15B Gene

Protein Domains for MYO15B Gene

Suggested Antigen Peptide Sequences for MYO15B Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 IQ domain.
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
  • Contains 1 IQ domain.
  • Contains 1 myosin motor domain.
  • Contains 1 MyTH4 domain.
  • Contains 1 SH3 domain.
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
genes like me logo Genes that share domains with MYO15B: view

Function for MYO15B Gene

Molecular function for MYO15B Gene

UniProtKB/Swiss-Prot Function:
Unknown, due to the absence of a functional motor domain.

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MYO15B Gene

Localization for MYO15B Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYO15B Gene


Subcellular locations from

Jensen Localization Image for MYO15B Gene COMPARTMENTS Subcellular localization image for MYO15B gene
Compartment Confidence
cytosol 3
cytoskeleton 2
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for MYO15B Gene

Pathways & Interactions for MYO15B Gene

SuperPathways for MYO15B Gene

No Data Available

Gene Ontology (GO) - Biological Process for MYO15B Gene


No data available for Pathways by source and SIGNOR curated interactions for MYO15B Gene

Drugs & Compounds for MYO15B Gene

No Compound Related Data Available

Transcripts for MYO15B Gene

Unigene Clusters for MYO15B Gene

Myosin XVB pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MYO15B Gene

No ASD Table

Relevant External Links for MYO15B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MYO15B Gene

mRNA expression in normal human tissues for MYO15B Gene

Protein differential expression in normal tissues from HIPED for MYO15B Gene

This gene is overexpressed in Fetal gut (58.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MYO15B Gene

Protein tissue co-expression partners for MYO15B Gene

NURSA nuclear receptor signaling pathways regulating expression of MYO15B Gene:


SOURCE GeneReport for Unigene cluster for MYO15B Gene:


mRNA Expression by UniProt/SwissProt for MYO15B Gene:

Tissue specificity: Detected in brain, stomach and kidney.
genes like me logo Genes that share expression patterns with MYO15B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for MYO15B Gene

Orthologs for MYO15B Gene

This gene was present in the common ancestor of animals.

Orthologs for MYO15B Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia MYO15B 35
(Monodelphis domestica)
Mammalia MYO15B 35
(Mus musculus)
Mammalia Myo15b 35
  • 8 (a)
(Ornithorhynchus anatinus)
Mammalia MYO15B 35
  • 7 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 5 (a)
fruit fly
(Drosophila melanogaster)
Insecta d 35
  • 4 (a)
(Caenorhabditis elegans)
Secernentea hum-4 35
  • 2 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2003 35
  • 4 (a)
Species where no ortholog for MYO15B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for MYO15B Gene

Gene Tree for MYO15B (if available)
Gene Tree for MYO15B (if available)

Paralogs for MYO15B Gene

Paralogs for MYO15B Gene

genes like me logo Genes that share paralogs with MYO15B: view

Variants for MYO15B Gene

Sequence variations from dbSNP and Humsavar for MYO15B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs10808 -- 75,620,773(+) TGCCC(C/G)CTCCT intron-variant
rs10814 -- 75,620,840(+) GCTGG(A/G)TGCTG intron-variant
rs11470 -- 75,620,784(+) GATGG(A/C)TCGCC intron-variant
rs707709 -- 75,591,559(-) GGCAC(A/G)TAGGA intron-variant
rs707710 -- 75,588,194(-) CCCTG(A/C/G/T)CCGCC nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MYO15B Gene

Variant ID Type Subtype PubMed ID
dgv373n27 CNV gain 19166990
nsv470603 CNV loss 18288195
nsv470604 CNV gain 18288195
nsv516133 CNV loss 19592680
nsv576027 CNV gain 21841781
nsv576030 CNV gain 21841781
nsv576031 CNV loss 21841781
nsv576032 CNV gain 21841781
nsv576033 CNV loss 21841781
nsv833543 CNV loss 17160897
nsv833544 CNV loss 17160897

Variation tolerance for MYO15B Gene

Gene Damage Index Score: 12.73; 94.66% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MYO15B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYO15B Gene

Disorders for MYO15B Gene

Relevant External Links for MYO15B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MYO15B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MYO15B Gene

Publications for MYO15B Gene

  1. A millennial myosin census. (PMID: 11294886) Berg J.S. … Cheney R.E. (Mol. Biol. Cell 2001) 2 3 4 65
  2. Human myosin XVBP is a transcribed pseudogene. (PMID: 11964073) Boger E.T. … Friedman T.B. (J. Muscle Res. Cell Motil. 2001) 3 4 22 65
  3. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 3 4 65
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65
  5. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (PMID: 23443559) Fogeron M.L. … Lange B.M. (Nat Commun 2013) 3 65

Products for MYO15B Gene

Sources for MYO15B Gene

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