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Aliases for MYO15B Gene

Aliases for MYO15B Gene

  • Myosin XVB Pseudogene 2 3
  • Myosin XVBP 3 4
  • MYO15BP 3 4
  • Unconventional Myosin XVBP Pseudogene 3
  • Unconventional Myosin-15B 4
  • Myosin XVB 3
  • KIAA1783 4

External Ids for MYO15B Gene

Previous GeneCards Identifiers for MYO15B Gene

  • GC17P073562
  • GC17P076610
  • GC17P074048
  • GC17P074182
  • GC17P074214
  • GC17P071096
  • GC17P069007
  • GC17P073586

Summaries for MYO15B Gene

GeneCards Summary for MYO15B Gene

MYO15B (Myosin XVB Pseudogene) is a Protein Coding gene. An important paralog of this gene is MYO1D.

UniProtKB/Swiss-Prot for MYO15B Gene

  • Unknown, due to the absence of a functional motor domain

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYO15B Gene

Genomics for MYO15B Gene

Regulatory Elements for MYO15B Gene

Genomic Location for MYO15B Gene

Start:
75,588,058 bp from pter
End:
75,626,849 bp from pter
Size:
38,792 bases
Orientation:
Plus strand

Genomic View for MYO15B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MYO15B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYO15B Gene

Proteins for MYO15B Gene

  • Protein details for MYO15B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96JP2-MY15B_HUMAN
    Recommended name:
    Unconventional myosin-XVB
    Protein Accession:
    Q96JP2
    Secondary Accessions:

    Protein attributes for MYO15B Gene

    Size:
    1530 amino acids
    Molecular mass:
    167118 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB47412.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for MYO15B Gene

neXtProt entry for MYO15B Gene

Proteomics data for MYO15B Gene at MOPED

Post-translational modifications for MYO15B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MYO15B Gene

Domains for MYO15B Gene

Gene Families for MYO15B Gene

HGNC:
  • MYOXV :Myosins / Myosin superfamily : Class XV

Protein Domains for MYO15B Gene

Suggested Antigen Peptide Sequences for MYO15B Gene

Graphical View of Domain Structure for InterPro Entry

Q96JP2

UniProtKB/Swiss-Prot:

MY15B_HUMAN :
  • Q96JP2
Domain:
  • Contains 1 IQ domain.
  • Contains 1 myosin motor domain.
  • Contains 1 MyTH4 domain.
  • Contains 1 SH3 domain.
Family:
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
genes like me logo Genes that share domains with MYO15B: view

Function for MYO15B Gene

Molecular function for MYO15B Gene

UniProtKB/Swiss-Prot Function: Unknown, due to the absence of a functional motor domain

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MYO15B Gene

Localization for MYO15B Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYO15B Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MYO15B Gene COMPARTMENTS Subcellular localization image for MYO15B gene
Compartment Confidence
cytosol 3
cytoskeleton 2
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for MYO15B Gene

Pathways for MYO15B Gene

SuperPathways for MYO15B Gene

No Data Available

Interacting Proteins for MYO15B Gene

Gene Ontology (GO) - Biological Process for MYO15B Gene

None

No data available for Pathways by source for MYO15B Gene

Transcripts for MYO15B Gene

Unigene Clusters for MYO15B Gene

Myosin XVB pseudogene:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MYO15B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MYO15B Gene

No ASD Table

Relevant External Links for MYO15B Gene

GeneLoc Exon Structure for
MYO15B
ECgene alternative splicing isoforms for
MYO15B

Expression for MYO15B Gene

mRNA expression in normal human tissues for MYO15B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for MYO15B Gene

SOURCE GeneReport for Unigene cluster for MYO15B Gene Hs.390817

mRNA Expression by UniProt/SwissProt for MYO15B Gene

Q96JP2-MY15B_HUMAN
Tissue specificity: Detected in brain, stomach and kidney
genes like me logo Genes that share expressions with MYO15B: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for MYO15B Gene

Orthologs for MYO15B Gene

This gene was present in the common ancestor of animals.

Orthologs for MYO15B Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia MYO15B 36
OneToOne
mouse
(Mus musculus)
Mammalia Myo15b 16
Myo15b 36
  • 8 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MYO15B 36
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MYO15B 36
  • 7 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 5 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta d 36
  • 4 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea hum-4 36
  • 2 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2003 36
  • 4 (a)
OneToMany
Species with no ortholog for MYO15B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for MYO15B Gene

ENSEMBL:
Gene Tree for MYO15B (if available)
TreeFam:
Gene Tree for MYO15B (if available)

Paralogs for MYO15B Gene

Paralogs for MYO15B Gene

genes like me logo Genes that share paralogs with MYO15B: view

Variants for MYO15B Gene

Sequence variations from dbSNP and Humsavar for MYO15B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs10808 -- 75,620,773(+) TGCCC(C/G)CTCCT intron-variant
rs10814 -- 75,620,840(+) GCTGG(A/G)TGCTG intron-variant
rs11470 -- 75,620,784(+) GATGG(A/C)TCGCC intron-variant
rs707709 -- 75,591,559(-) GGCAC(A/G)TAGGA intron-variant
rs707710 -- 75,588,194(-) CCCTG(A/C/G/T)CCGCC nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MYO15B Gene

Variant ID Type Subtype PubMed ID
nsv516133 CNV Loss 19592680
dgv3256n71 CNV Loss 21882294
nsv470603 CNV Loss 18288195
dgv3257n71 CNV Loss 21882294
nsv833543 CNV Loss 17160897
nsv908777 CNV Loss 21882294
dgv3259n71 CNV Loss 21882294
dgv3260n71 CNV Loss 21882294
dgv3261n71 CNV Loss 21882294
dgv3262n71 CNV Loss 21882294
dgv3263n71 CNV Loss 21882294
nsv908790 CNV Loss 21882294
nsv908794 CNV Loss 21882294
dgv3264n71 CNV Loss 21882294
dgv373n27 CNV Gain 19166990
nsv470604 CNV Gain 18288195
dgv3265n71 CNV Loss 21882294
nsv833544 CNV Loss 17160897
nsv908800 CNV Loss 21882294

Relevant External Links for MYO15B Gene

HapMap Linkage Disequilibrium report
MYO15B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYO15B Gene

Disorders for MYO15B Gene

No disorders were found for MYO15B Gene.

No data available for UniProtKB/Swiss-Prot for MYO15B Gene

Publications for MYO15B Gene

  1. A millennial myosin census. (PMID: 11294886) Berg J.S. … Cheney R.E. (Mol. Biol. Cell 2001) 2 3 4
  2. Human myosin XVBP is a transcribed pseudogene. (PMID: 11964073) Boger E.T. … Friedman T.B. (J. Muscle Res. Cell Motil. 2001) 3 4 23
  3. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for MYO15B Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MYO15B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MYO15B
    • Block miRNA regulation of MYO15B using miScript Target Protectors

    Sources for MYO15B Gene

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