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Aliases for MYNN Gene

Aliases for MYNN Gene

  • Myoneurin 2 3
  • Zinc Finger And BTB Domain-Containing Protein 31 3 4
  • ZBTB31 3 4
  • OSZF 3 4
  • Zinc Finger Protein With BTB/POZ Domain 3
  • SBBIZ1 3
  • ZNF902 3

External Ids for MYNN Gene

Summaries for MYNN Gene

Entrez Gene Summary for MYNN Gene

  • This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 14. [provided by RefSeq, Jun 2010]

GeneCards Summary for MYNN Gene

MYNN (Myoneurin) is a Protein Coding gene. Diseases associated with MYNN include lung cancer. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ENSG00000254553.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYNN Gene

Genomics for MYNN Gene

Genomic Location for MYNN Gene

Start:
169,772,401 bp from pter
End:
169,789,716 bp from pter
Size:
17,316 bases
Orientation:
Plus strand

Genomic View for MYNN Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MYNN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYNN Gene

Regulatory Elements for MYNN Gene

Proteins for MYNN Gene

  • Protein details for MYNN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NPC7-MYNN_HUMAN
    Recommended name:
    Myoneurin
    Protein Accession:
    Q9NPC7
    Secondary Accessions:
    • B2R6C9
    • Q6QHA6
    • Q6QHA7
    • Q6R3G1
    • Q6R3G2
    • Q6R4A0
    • Q7Z716
    • Q7Z717
    • Q86Z11
    • Q86Z12
    • Q9NS01
    • Q9UIW8

    Protein attributes for MYNN Gene

    Size:
    610 amino acids
    Molecular mass:
    68682 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MYNN Gene

    Alternative splice isoforms for MYNN Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MYNN Gene

Proteomics data for MYNN Gene at MOPED

Post-translational modifications for MYNN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MYNN Gene

No data available for DME Specific Peptides for MYNN Gene

Domains for MYNN Gene

Gene Families for MYNN Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type
  • BTBD :BTB/POZ domain containing

Protein Domains for MYNN Gene

UniProtKB/Swiss-Prot:

MYNN_HUMAN
Domain:
  • Contains 1 BTB (POZ) domain.:
    • Q9NPC7
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9NPC7
Similarity:
  • Contains 8 C2H2-type zinc fingers.:
    • Q9NPC7
genes like me logo Genes that share domains with MYNN: view

Function for MYNN Gene

Gene Ontology (GO) - Molecular Function for MYNN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding --
GO:0008270 zinc ion binding TAS 10873615
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with MYNN: view

Phenotypes for MYNN Gene

GenomeRNAi human phenotypes for MYNN:
genes like me logo Genes that share phenotypes with MYNN: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MYNN Gene

Localization for MYNN Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYNN Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MYNN Gene COMPARTMENTS Subcellular localization image for MYNN gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for MYNN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with MYNN: view

Pathways for MYNN Gene

SuperPathways for MYNN Gene

No Data Available

Gene Ontology (GO) - Biological Process for MYNN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with MYNN: view

No data available for Pathways by source for MYNN Gene

Transcripts for MYNN Gene

Unigene Clusters for MYNN Gene

Myoneurin:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MYNN Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c · 12d ·
SP1: - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - -
SP5:
SP6: - - -
SP7: - - -
SP8: - - -
SP9: - -
SP10:
SP11: - - - - -
SP12: - -

ExUns: 12e
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:

Relevant External Links for MYNN Gene

GeneLoc Exon Structure for
MYNN
ECgene alternative splicing isoforms for
MYNN

Expression for MYNN Gene

mRNA expression in normal human tissues for MYNN Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MYNN Gene

SOURCE GeneReport for Unigene cluster for MYNN Gene Hs.507025

mRNA Expression by UniProt/SwissProt for MYNN Gene

Q9NPC7-MYNN_HUMAN
Tissue specificity: Mainly expressed in the neuromuscular system. Located in and around synaptic myonuclei in adult muscle. Expression is dysregulated after nerve injury. Also found in the testis, ovary and placenta.
genes like me logo Genes that share expressions with MYNN: view

Orthologs for MYNN Gene

This gene was present in the common ancestor of animals.

Orthologs for MYNN Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MYNN 36
  • 99.67 (n)
  • 100 (a)
MYNN 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MYNN 36
  • 92.25 (n)
  • 93.98 (a)
MYNN 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MYNN 36
  • 94.37 (n)
  • 96.23 (a)
MYNN 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mynn 36
  • 87.92 (n)
  • 91.97 (a)
Mynn 16
Mynn 37
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MYNN 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MYNN 37
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mynn 36
  • 86.97 (n)
  • 90.38 (a)
chicken
(Gallus gallus)
Aves MYNN 36
  • 77.21 (n)
  • 82.13 (a)
MYNN 37
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MYNN 37
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492148 36
  • 66.33 (n)
  • 63.95 (a)
zebrafish
(Danio rerio)
Actinopterygii -- 36
mynn 37
  • 29 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta rgr 38
  • 35 (a)
CG1602 38
  • 36 (a)
Species with no ortholog for MYNN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MYNN Gene

ENSEMBL:
Gene Tree for MYNN (if available)
TreeFam:
Gene Tree for MYNN (if available)

Paralogs for MYNN Gene

Selected SIMAP similar genes for MYNN Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for MYNN Gene

genes like me logo Genes that share paralogs with MYNN: view

Variants for MYNN Gene

Sequence variations from dbSNP and Humsavar for MYNN Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1317082 -- 169,779,797(+) TAAGT(A/G)TGTTG intron-variant
rs1881966 -- 169,778,152(+) GCTGC(A/G)GTGAG intron-variant
rs1920120 -- 169,784,392(+) CTGTT(C/T)ATGAA intron-variant
rs1920121 -- 169,787,865(+) CCCAC(A/G)TATTA utr-variant-3-prime, nc-transcript-variant
rs1920122 -- 169,788,353(+) TGTAT(C/T)AAGTT utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MYNN Gene

Variant ID Type Subtype PubMed ID
nsv7356 OTHER Inversion 18451855
esv2422204 CNV Deletion 17116639

Relevant External Links for MYNN Gene

HapMap Linkage Disequilibrium report
MYNN

Disorders for MYNN Gene

(1) MalaCards Diseases for MYNN Gene

Search for MYNN Gene in MalaCards »

Relevant External Links for MYNN

Genetic Association Database (GAD)
MYNN
Human Genome Epidemiology (HuGE) Navigator
MYNN
genes like me logo Genes that share disorders with MYNN: view

No data available for UniProtKB/Swiss-Prot for MYNN Gene

Publications for MYNN Gene

  1. Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle. (PMID: 10873615) Alliel P.M. … Perin J.-P. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 23
  2. Neuromuscular expression of the BTB/POZ and zinc finger protein myoneurin. (PMID: 14694499) Cifuentes-Diaz C. … Alliel P.M. (Muscle Nerve 2004) 3 4 23
  3. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PMID: 18676680) Hosgood H.D. … Lan Q. (Carcinogenesis 2008) 3 49
  4. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M. … Lan Q. (Environ. Mol. Mutagen. 2009) 3 49
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for MYNN Gene

  • Addgene plasmids for MYNN

Sources for MYNN Gene

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