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Aliases for MYNN Gene

Aliases for MYNN Gene

  • Myoneurin 2 3 5
  • Zinc Finger And BTB Domain-Containing Protein 31 3 4
  • ZBTB31 3 4
  • OSZF 3 4
  • Zinc Finger Protein With BTB/POZ Domain 3
  • SBBIZ1 3
  • ZNF902 3

External Ids for MYNN Gene

Previous GeneCards Identifiers for MYNN Gene

  • GC03P166758
  • GC03P170539
  • GC03P170892
  • GC03P170812
  • GC03P170973
  • GC03P169490
  • GC03P166860

Summaries for MYNN Gene

Entrez Gene Summary for MYNN Gene

  • This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 14. [provided by RefSeq, Jun 2010]

GeneCards Summary for MYNN Gene

MYNN (Myoneurin) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ENSG00000254553.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYNN Gene

Genomics for MYNN Gene

Regulatory Elements for MYNN Gene

Promoters for MYNN Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MYNN on UCSC Golden Path with GeneCards custom track

Genomic Location for MYNN Gene

169,769,649 bp from pter
169,789,716 bp from pter
20,068 bases
Plus strand

Genomic View for MYNN Gene

Genes around MYNN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MYNN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MYNN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYNN Gene

Proteins for MYNN Gene

  • Protein details for MYNN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • B2R6C9
    • Q6QHA6
    • Q6QHA7
    • Q6R3G1
    • Q6R3G2
    • Q6R4A0
    • Q7Z716
    • Q7Z717
    • Q86Z11
    • Q86Z12
    • Q9NS01
    • Q9UIW8

    Protein attributes for MYNN Gene

    610 amino acids
    Molecular mass:
    68682 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MYNN Gene

    Alternative splice isoforms for MYNN Gene


neXtProt entry for MYNN Gene

Proteomics data for MYNN Gene at MOPED

Post-translational modifications for MYNN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MYNN Gene

Antibody Products

No data available for DME Specific Peptides for MYNN Gene

Domains & Families for MYNN Gene

Gene Families for MYNN Gene

Protein Domains for MYNN Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 BTB (POZ) domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
  • Contains 1 BTB (POZ) domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with MYNN: view

Function for MYNN Gene

Gene Ontology (GO) - Molecular Function for MYNN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IEA --
genes like me logo Genes that share ontologies with MYNN: view
genes like me logo Genes that share phenotypes with MYNN: view

Animal Model Products

miRNA for MYNN Gene

miRTarBase miRNAs that target MYNN

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MYNN Gene

Localization for MYNN Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYNN Gene

Subcellular locations from

Jensen Localization Image for MYNN Gene COMPARTMENTS Subcellular localization image for MYNN gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for MYNN Gene

Pathways & Interactions for MYNN Gene

SuperPathways for MYNN Gene

No Data Available

Gene Ontology (GO) - Biological Process for MYNN Gene


No data available for Pathways by source and SIGNOR curated interactions for MYNN Gene

Drugs & Compounds for MYNN Gene

No Compound Related Data Available

Transcripts for MYNN Gene

Unigene Clusters for MYNN Gene

Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MYNN Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c · 12d ·
SP1: - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - -
SP6: - - -
SP7: - - -
SP8: - - -
SP9: - -
SP11: - - - - -
SP12: - -

ExUns: 12e

Relevant External Links for MYNN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MYNN Gene

mRNA expression in normal human tissues for MYNN Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for MYNN Gene

SOURCE GeneReport for Unigene cluster for MYNN Gene Hs.507025

mRNA Expression by UniProt/SwissProt for MYNN Gene

Tissue specificity: Mainly expressed in the neuromuscular system. Located in and around synaptic myonuclei in adult muscle. Expression is dysregulated after nerve injury. Also found in the testis, ovary and placenta.
genes like me logo Genes that share expression patterns with MYNN: view

Protein tissue co-expression partners for MYNN Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and Protein differential expression in normal tissues for MYNN Gene

Orthologs for MYNN Gene

This gene was present in the common ancestor of animals.

Orthologs for MYNN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MYNN 35
  • 92.25 (n)
  • 93.98 (a)
  • 95 (a)
(Canis familiaris)
Mammalia MYNN 35
  • 94.37 (n)
  • 96.23 (a)
  • 96 (a)
(Mus musculus)
Mammalia Mynn 35
  • 87.92 (n)
  • 91.97 (a)
Mynn 16
Mynn 36
  • 92 (a)
(Pan troglodytes)
Mammalia MYNN 35
  • 99.67 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Mynn 35
  • 86.97 (n)
  • 90.38 (a)
(Monodelphis domestica)
Mammalia MYNN 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia MYNN 36
  • 83 (a)
(Gallus gallus)
Aves MYNN 35
  • 77.21 (n)
  • 82.13 (a)
  • 75 (a)
(Anolis carolinensis)
Reptilia MYNN 36
  • 80 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492148 35
  • 66.33 (n)
  • 63.95 (a)
(Danio rerio)
Actinopterygii -- 35
mynn 36
  • 29 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1602 37
  • 36 (a)
rgr 37
  • 35 (a)
Species with no ortholog for MYNN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MYNN Gene

Gene Tree for MYNN (if available)
Gene Tree for MYNN (if available)

Paralogs for MYNN Gene

(378) SIMAP similar genes for MYNN Gene using alignment to 3 proteins: Pseudogenes for MYNN Gene

genes like me logo Genes that share paralogs with MYNN: view

Variants for MYNN Gene

Sequence variations from dbSNP and Humsavar for MYNN Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1317082 -- 169,779,797(+) TAAGT(A/G)TGTTG intron-variant
rs1920120 -- 169,784,392(+) CTGTT(C/T)ATGAA intron-variant
rs1920121 -- 169,787,865(+) CCCAC(A/G)TATTA nc-transcript-variant, utr-variant-3-prime
rs1920122 -- 169,788,353(+) TGTAT(C/T)AAGTT nc-transcript-variant, utr-variant-3-prime
rs1920123 -- 169,788,385(+) ATTTA(C/T)AAAGC nc-transcript-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MYNN Gene

Variant ID Type Subtype PubMed ID
nsv7356 OTHER Inversion 18451855
esv2422204 CNV Deletion 17116639

Variation tolerance for MYNN Gene

Residual Variation Intolerance Score: 40.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.67; 31.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MYNN Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYNN Gene

Disorders for MYNN Gene

Relevant External Links for MYNN

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MYNN Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MYNN Gene

Publications for MYNN Gene

  1. Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle. (PMID: 10873615) Alliel P.M. … Perin J.-P. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 23 67
  2. Neuromuscular expression of the BTB/POZ and zinc finger protein myoneurin. (PMID: 14694499) Cifuentes-Diaz C. … Alliel P.M. (Muscle Nerve 2004) 3 23
  3. HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP. (PMID: 25925205) Bhattacharya S. … Ghosh M.K. (Cell Oncol (Dordr) 2015) 3
  4. Genome-wide association study identifies multiple loci associated with bladder cancer risk. (PMID: 24163127) Figueroa J.D. … Rothman N. (Hum. Mol. Genet. 2014) 3
  5. A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. (PMID: 24292274) Speedy H.E. … Houlston R.S. (Nat. Genet. 2014) 3

Products for MYNN Gene

Sources for MYNN Gene

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