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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MYLPF Gene

protein-coding   GIFtS: 51
GCID: GC16P030387

myosin light chain, phosphorylatable, fast skeletal muscle
 Explore 2 diseases affiliated with
MYLPF via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MYLPF    

Aliases
for MYLPF gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Myosin Light Chain, Phosphorylatable, Fast Skeletal Muscle1 2     MLC2B2 3
HUMMLC2B1 2     Myosin Light Chain 22
MRLC21 2     Myosin Regulatory Light Chain 2, Skeletal Muscle Isoform2
MYL111 2     Myosin, Light Chain 11, Regulatory2
Fast Skeletal Myosin Light Chain 22 3     

External Ids:    HGNC: 298241   Entrez Gene: 298952   Ensembl: ENSG000001802097   UniProtKB: Q96A323   

Export aliases for MYLPF gene to outside databases

Previous GC identifers: GC16P030294 GC16P030297 GC16P027947


Summaries
for MYLPF gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for MYLPF gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYLPF gene promoter:
         Bach1   HOXA9   HOXA9B   Elk-1   p53   C/EBPalpha   Meis-1b   HFH-1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MYLPF promoter sequence
   Search SABiosciences Chromatin IP Primers for MYLPF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYLPF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

MYLPF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYLPF gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P030387:  view genomic region     (about GC identifiers)

Start:
 30,382,255 bp from pter      End:
 30,389,312 bp from pter
Size:
 7,058 bases      Orientation:
 plus strand

Proteins
for MYLPF gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MLRS_HUMAN, Q96A32 (See protein sequence)
Recommended Name: Myosin regulatory light chain 2, skeletal muscle isoform  
Size: 169 amino acids; 19015 Da
Subunit: Myosin is a hexamer of 2 heavy chains and 4 light chains
Miscellaneous: This chain binds calcium
Secondary accessions: B2RA83 Q14843 Q6IB41

Explore the universe of human proteins at neXtProt for MYLPF: NX_Q96A32

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96A32

    • MYLPF Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_037424.2  
    ENSEMBL proteins: 
     ENSP00000454444   ENSP00000454694   ENSP00000325239   ENSP00000455356  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein: MYLPF
    OriGene Protein Over-expression Lysate: MYLPF
    OriGene Custom Protein Services for MYLPF 
    GenScript Custom Purified and Recombinant Proteins Services for MYLPF
    Novus Biologicals MYLPF Proteins
    Novus Biologicals MYLPF Lysate
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for MYLPF
    Uscn Proteins for MYLPF

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005859muscle myosin complex TAS6179945


    MYLPF for ontologies           About GeneDecksing



    MYLPF Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of MYLPF
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    Uscn Antibodies for MYLPF
    Search ThermoFisher Antibodies for MYLPF

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    Uscn ELISAs and CLIAs for MYLPF

    Protein Domains /
    Families
    for MYLPF gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MYLPF for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR018247 EF_Hand_1_Ca_BS
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd

    Graphical View of Domain Structure for InterPro Entry Q96A32

    ProtoNet protein and cluster: Q96A32

    UniProtKB/Swiss-Prot: MLRS_HUMAN, Q96A32
    Similarity: Contains 3 EF-hand domains


    Function
    for MYLPF gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYLPF
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MYLPF
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYLPF (see all 7)
    OriGene shRNA RFP: MYLPF
    OriGene siRNA: MYLPF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYLPF

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for MYLPF

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYLPF (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYLPF
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MYLPF (NM_013292)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYLPF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYLPF 

    Cell Line
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    Search LifeMap BioReagents cell lines for MYLPF

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for MYLPF

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0008307structural constituent of muscle ISS--


    MYLPF for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for MYLPF:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
         Mouse knock-out Mylpftm1Jdp for MYLPF
         5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mylpf):
     cardiovascular system  growth/size  mortality/aging  muscle  respiratory system 

    MYLPF for phenotypes           About GeneDecksing


    Pathways & Interactions
    for MYLPF gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell adhesion_Integrin-mediated cell adhesion and migration
    		Cell adhesion_Integrin-mediated cell adhesion and migration1.00
    		Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    		Cell adhesion Integrin-mediated cell adhesion and migration1.00
    		Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases0.49
    2Immune response _CCR3 signaling in eosinophils
    		Immune response _CCR3 signaling in eosinophils1.00
    		Inhibitory action of Lipoxins on neutrophil migration0.51
    		Immune response CCR3 signaling in eosinophils1.00
    3Cell adhesion Tight junctions
    		Cell adhesion Tight junctions1.00
    		Cell adhesion_Tight junctions0.99
    4Development MAG-dependent inhibition of neurite outgrowth
    		Development MAG-dependent inhibition of neurite outgrowth1.00
    		Development_MAG-dependent inhibition of neurite outgrowth0.87
    5ErbB1 downstream signaling
    		ErbB1 downstream signaling1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5 EMD Millipore Pathways for MYLPF
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cell adhesion Tight junctions
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Immune response CCR3 signaling in eosinophils
    Development MAG-dependent inhibition of neurite outgrowth


    5/6 GeneGo (Thomson Reuters) Pathways for MYLPF (see all 6)
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Inhibitory action of Lipoxins on neutrophil migration
    Immune response CCR3 signaling in eosinophils
    Cell adhesion Tight junctions

    1 BioSystems Pathway for MYLPF 
        ErbB1 downstream signaling


    4         Kegg Pathways  (Kegg details for MYLPF):
        Focal adhesion
    Tight junction
    Leukocyte transendothelial migration
    Regulation of actin cytoskeleton


    MYLPF for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MYLPF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/43 Interacting proteins for MYLPF (Q96A323 ENSP000003252394) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LIN37Q96GY33, ENSP000003011594I2D: score=1 STRING: ENSP00000301159
    PPP2CBP627143, ENSP000002211384I2D: score=1 STRING: ENSP00000221138
    PPP2R4Q152573, ENSP000003518854I2D: score=1 STRING: ENSP00000351885
    C12orf44Q9BSB43I2D: score=1 
    KCNMA1Q127913I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response IEA--
    GO:0007519skeletal muscle tissue development ISS--


    MYLPF for ontologies           About GeneDecksing



    Drugs & Compounds
    for MYLPF gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MYLPF

    1 HMDB Compound for MYLPF    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Search CenterWatch for drugs/clinical trials and news about MYLPF / MLRS 

    Transcripts
    for MYLPF gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MYLPF gene: 
    NM_013292.3  

    Unigene Cluster for MYLPF:

    Myosin light chain, phosphorylatable, fast skeletal muscle
    Hs.50889  [show with all ESTs]
    Unigene Representative Sequence: BF575830
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563718 ENST00000568749 ENST00000322861(uc002dxv.1) ENST00000566955
    ENST00000563728

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYLPF
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MYLPF
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYLPF (see all 7)
    OriGene shRNA RFP: MYLPF
    OriGene siRNA: MYLPF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYLPF
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYLPF (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYLPF
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MYLPF (NM_013292)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYLPF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYLPF 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYLPF
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYLPF
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYLPF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYLPF

    Additional cDNA sequence: 

    AF363061.1 AK314082.1 BC012571.1 BX649054.1 CR456963.1 M21812.1 X57543.1 

    6 DOTS entries:

    DT.452274  DT.95285371  DT.100038668  DT.100814122  DT.95285369  DT.95285384 

    24/344 AceView cDNA sequences (see all 344):

    F33719 F29456 F26740 F28439 F18303 AA346164 F24662 F30841 
    F25243 AW450387 F31960 AI139265 AJ572895 AJ572433 F28014 F15741 
    F26125 F29065 F36283 F28275 AA341931 AA346165 F30771 AJ573671 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MYLPF    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b
    SP1:                                                                              
    SP2:              -                                                               
    SP3:                                -                                             
    SP4:                                                                              


    ECgene alternative splicing isoforms for MYLPF

    Expression
    for MYLPF gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MYLPF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGGGCGGCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MYLPF expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Head MesenchymeHead MesenchymeHead Mesenchyme
    LimbAutopodLimb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor SK17 (Embryonic Progenitor Cell)

    See MYLPF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MYLPF

    SOURCE GeneReport for Unigene cluster: Hs.50889

    UniProtKB/Swiss-Prot: MLRS_HUMAN, Q96A32
    Tissue specificity: Expressed in fetal and adult skeletal muscle

        SABiosciences Custom PCR Arrays for MYLPF
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYLPF
    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for MYLPF

    Orthologs
    for MYLPF gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MYLPF gene from 6/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia MYLPF6
    		 --
    		 62(a)
    		 1 ↔ 1
    		 GL343516.1(305617-314174)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.62632 Xenopus laevis mRNA similar to (clone PWHLC2-24) myosin light chain 2 (cDNA clone MGC52956 IMAGE4930423), complete cds less 81.25(n)    BC053808.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii mylz22 myosin, light polypeptide 2, skeletal muscle 82.01(n)   30429  AF081462.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Mlc26
    Eip63F-16
    (see all 3)    		 Ecdysone-induced protein 63F 1
    (see all 3)    		 27(a)
    17(a)
    (see all 3)    		 possible ortholog
    possible ortholog
    (see all 3)    		 3R(25997160-26000273)
    3L(3909973-3935617)
    worm
    (Caenorhabditis elegans)    		 Secernentea mlc-21 Protein MLC-2 59.3(n)
    50.31(a)    		   181775  NM_078427.4  NP_510828.1 
    rice
    (Oryza sativa)    		 Liliopsida --
    		 OsCML9 - Calmodulin-related calcium sensor protein...
    		 23(a)
    		 possible ortholog
    		 5(24067532-24068539)


    ENSEMBL Gene Tree for MYLPF (if available)
    TreeFam Gene Tree for MYLPF (if available) 

    Paralogs
    for MYLPF gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MYLPF gene
    MYL12A2  MYL72  MYL102  MYL92  MYL52  MYL22  MYL12B2  
    13 SIMAP similar genes for MYLPF using alignment to 4 protein entries:     MLRS_HUMAN (see all proteins):
    MYL2    MYL5    MYL12A    MRLC3    MYL9    MYL12B
    MYL7    MYL10    CALM1    CALM3    CALM2    CALML3
    MYL6

    MYLPF for paralogs           About GeneDecksing



    Genomic Variants
    for MYLPF gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/67 NCBI SNPs in MYLPF are shown (see all 67)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs99282181,2
    		C,F,H,--30384400(+) GATGGG/AAACTA 1 -- us2k113Minor allele frequency- A:0.18NS NA WA CSA 1594
    rs72011801,2
    		C,A,--30384736(+) gcgggA/Gaaacc 1 -- us2k1 tfbs30--------
    rs1435194251,2
    		--30385234(+) GTGGGA/GGTGGA 1 -- us2k10--------
    rs1882415111,2
    		--30385254(+) TCTGCC/TAAAGT 1 -- us2k10--------
    rs118631501,2
    		C,F,A,H,--30385503(+) GCTTCA/GTGGCA 1 -- us2k127Minor allele frequency- G:0.34NS EA NA WA CSA 2777
    rs1912895481,2
    		--30385504(+) CTTCGC/TGGCAC 1 -- us2k10--------
    rs1835942251,2
    		--30385511(+) GCACAC/GCTATA 1 -- us2k10--------
    rs711490101,2
    		C--30385635(+) AAAAA-/AGGGAG 1 -- us2k12Minor allele frequency- A:0.25NA 4
    rs2016341381,2
    		--30385647(+) AAAAA-/GAGGGA 1 -- us2k10--------
    rs80508121,2
    		C,F,A,H,--30385837(+) CAGAAC/TGATGC 1 -- us2k127Minor allele frequency- T:0.18NS EA MN NA WA CSA 3603

    HapMap Linkage Disequilibrium report for MYLPF (30382255 - 30389312 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MYLPF: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for MYLPF gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MYLPF for disorders           About GeneDecksing

    2 diseases for MYLPF:    About MalaCards
    hermaphroditism    pharyngitis


    Export disorders for MYLPF gene to outside databases

    Publications
    for MYLPF gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MYLPF gene integrated from 9 sources:
    (articles sorted by number of sources associating them with MYLPF)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships. (PubMed id 14756420)1, 2 Sachdev S.... Sarkar S. (2003)
    3. Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin. (PubMed id 6179945)1, 3 Garfinkel L.I....Nadal-Ginard B. (1982)
    4. An integrated workflow for charting the human interac tion proteome: insights into the PP2A system. (PubMed id 19156129)1 Glatter T....Gstaiger M. (2009)
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. The nucleotide sequence of a rat myosin light chain 2 gene. (PubMed id 6091059)1 Nudel U....Levy Z. (1984)

    External Searches for MYLPF gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing MYLPF gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29895 HGNC: 29824 AceView: HUMMLC2B Ensembl:ENSG00000180209 euGenes: HUgn29895
    ECgene: MYLPF Kegg: 29895 H-InvDB: MYLPF

    Other Databases showing MYLPF gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MYLPF gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MYLPF Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MYLPF gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MYLPF gene:
    Search GeneIP for patents involving MYLPF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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