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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MYLPF Gene

protein-coding   GIFtS: 52
GCID: GC16P030387

Myosin Light Chain, Phosphorylatable, Fast Skeletal Muscle

  Search for MYLPF
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Myosin Light Chain, Phosphorylatable, Fast Skeletal Muscle1 2     HUMMLC2B2
Fast Skeletal Myosin Light Chain 22 3     MRLC22
MLC2B2 3     MYL112
Light Chain 111     Myosin Light Chain 22
myosin1     Myosin Regulatory Light Chain 2, Skeletal Muscle Isoform2
Myosin Regulatory Light Chain 21     Myosin, Light Chain 11, Regulatory2
regulatory1     

External Ids:    HGNC: 298241   Entrez Gene: 298952   Ensembl: ENSG000001802097   UniProtKB: Q96A323   

Export aliases for MYLPF gene to outside databases

Previous GC identifers: GC16P030294 GC16P030297 GC16P027947


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MYLPF Gene: 
MYLPF (myosin light chain, phosphorylatable, fast skeletal muscle) is a protein-coding gene. Among its related super-pathways are Immune response CCR3 signaling in eosinophils and Cell adhesion Integrin-mediated cell adhesion and migration. GO annotations related to this gene include structural constituent of muscle and calcium ion binding. An important paralog of this gene is MYL12A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYLPF gene promoter:
         Bach1   HOXA9   HOXA9B   Elk-1   p53   C/EBPalpha   Meis-1b   HFH-1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMYLPF promoter sequence
   Search SABiosciences Chromatin IP Primers for MYLPF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYLPF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

MYLPF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYLPF gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P030387:  view genomic region     (about GC identifiers)

Start:
30,382,255 bp from pter      End:
30,389,312 bp from pter
Size:
7,058 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MLRS_HUMAN, Q96A32 (See protein sequence)
Recommended Name: Myosin regulatory light chain 2, skeletal muscle isoform  
Size: 169 amino acids; 19015 Da
Subunit: Myosin is a hexamer of 2 heavy chains and 4 light chains
Miscellaneous: This chain binds calcium
Secondary accessions: B2RA83 Q14843 Q6IB41

Explore the universe of human proteins at neXtProt for MYLPF: NX_Q96A32

Explore proteomics data for MYLPF at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96A32

  • MYLPF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MYLPF Protein Expression
    REFSEQ proteins: NP_037424.2  
    ENSEMBL proteins: 
     ENSP00000454444   ENSP00000454694   ENSP00000325239   ENSP00000455356  

    Human Recombinant Protein Products for MYLPF: 
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    Novus Biologicals MYLPF Proteins
    Novus Biologicals MYLPF Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for MYLPF
    Cloud-Clone Corp. Proteins for MYLPF 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IDA17897319
    GO:0005859muscle myosin complex TAS6179945

    MYLPF for ontologies           About GeneDecksing



    MYLPF Antibody Products: 
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    Cloud-Clone Corp. ELISAs for MYLPF 
    Cloud-Clone Corp. CLIAs for MYLPF


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    EFHAND: EF-hand domain containing
    MYL: Myosins / Light chain

    3 InterPro protein domains:
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_dom
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry Q96A32

    ProtoNet protein and cluster: Q96A32

    UniProtKB/Swiss-Prot: MLRS_HUMAN, Q96A32
    Similarity: Contains 3 EF-hand domains


    MYLPF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0008307structural constituent of muscle ISS--
         
    MYLPF for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MYLPF:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mylpf):
     cardiovascular system  growth/size  mortality/aging  muscle  respiratory system 

    MYLPF for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Mylpftm1Jdp for MYLPF

       inGenious Targeting Laboratory - Custom generated mouse model solutions for MYLPF 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MYLPF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MYLPF 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MYLPF 

    miRNA
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    Inhib. RNA
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    OriGene ORF clones in mouse, rat for MYLPF
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    GenScript: all cDNA clones in your preferred vector: MYLPF (NM_013292)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYLPF
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                         Customized lentivirus expression plasmids for stable overexpression of MYLPF 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYLPF


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MYLPF About   (see all 8)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Immune response CCR3 signaling in eosinophils
    Immune response CCR3 signaling in eosinophils0.51
    Inhibitory action of Lipoxins on neutrophil migration0.51
    2Cell adhesion Integrin-mediated cell adhesion and migration
    Cell adhesion Integrin-mediated cell adhesion and migration0.49
    Cell adhesion Tight junctions0.33
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    3Development MAG-dependent inhibition of neurite outgrowth
    Development MAG-dependent inhibition of neurite outgrowth0.87
    4Focal Adhesion
    Focal adhesion0.64
    5Regulation of Actin Cytoskeleton
    Regulation of actin cytoskeleton0.57

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5 EMD Millipore Pathways for MYLPF
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cell adhesion Tight junctions
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Immune response CCR3 signaling in eosinophils
    Development MAG-dependent inhibition of neurite outgrowth


    5/6 GeneGo (Thomson Reuters) Pathways for MYLPF (see all 6)
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Inhibitory action of Lipoxins on neutrophil migration
    Immune response CCR3 signaling in eosinophils
    Cell adhesion Tight junctions

    1 BioSystems Pathway for MYLPF
        ErbB1 downstream signaling


    4         Kegg Pathways  (Kegg details for MYLPF):
        Focal adhesion
    Tight junction
    Leukocyte transendothelial migration
    Regulation of actin cytoskeleton


    MYLPF for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MYLPF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/43 Interacting proteins for MYLPF (Q96A323 ENSP000003252394) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LIN37Q96GY33, ENSP000003011594I2D: score=1 STRING: ENSP00000301159
    PPP2CBP627143, ENSP000002211384I2D: score=1 STRING: ENSP00000221138
    PPP2R4Q152573, ENSP000003518854I2D: score=1 STRING: ENSP00000351885
    C12orf44Q9BSB43I2D: score=1 
    KCNMA1Q127913I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response IEA--
    GO:0007519skeletal muscle tissue development ISS--

    MYLPF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MYLPF (MLRS)

    1 HMDB Compound for MYLPF    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about MYLPF / MLRS

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MYLPF gene: 
    NM_013292.3  

    Unigene Cluster for MYLPF:

    Myosin light chain, phosphorylatable, fast skeletal muscle
    Hs.50889  [show with all ESTs]
    Unigene Representative Sequence: BF575830
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563718 ENST00000568749 ENST00000322861(uc002dxv.1) ENST00000566955
    ENST00000563728
    miRNA
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MYLPF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYLPF
    Clone
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    OriGene ORF clones in mouse, rat for MYLPF
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    GenScript: all cDNA clones in your preferred vector: MYLPF (NM_013292)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYLPF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYLPF
    Sirion Biotech Customized lentivirus for stable overexpression of MYLPF 
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    Primer
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    OriGene qPCR primer pairs and template standards for MYLPF
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYLPF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYLPF

    Additional mRNA sequence: 

    AF363061.1 AK314082.1 BC012571.1 BX649054.1 CR456963.1 M21812.1 X57543.1 

    6 DOTS entries:

    DT.452274  DT.95285371  DT.100038668  DT.100814122  DT.95285369  DT.95285384 

    24/344 AceView cDNA sequences (see all 344):

    F29586 F31960 F30841 F25243 F24662 F29841 F26736 BU580421 
    AI199401 BQ899328 F21152 W76234 BX492369 F18698 F27549 F27359 
    AA330961 AA331022 AJ573671 CF552525 F29456 F24679 F36393 AW450387 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MYLPF    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b
    SP1:                                                                              
    SP2:              -                                                               
    SP3:                                -                                             
    SP4:                                                                              


    ECgene alternative splicing isoforms for MYLPF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MYLPF expression in normal human tissues (normalized intensities)      MYLPF embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGGCGGCCT
    MYLPF Expression
    About this image


    MYLPF expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/18 selected tissues (see all 18) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 8 entries
             Mononuclear Myocytes Hyoid Arch Muscles
             Human Skeletal Muscle Satellite Cells (HSkMSC)   
             cavities and their linings/intraembryonic coelom/diaphragm   
     
     Limb (Muscoskeletal System)    fully expand to see all 4 entries
             Autopod
             limb/hindlimb/leg   
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Beating cell clusters ( Spontaneous differentiation of cardiomyocytes and further...
             heart muscle ; myocytes   
     
     Smooth Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             smooth muscle ; smooth muscle cells   
     
     Colon (Gastrointestinal Tract)
             colon ; glandular cells   

    See MYLPF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MYLPF

    SOURCE GeneReport for Unigene cluster: Hs.50889

    UniProtKB/Swiss-Prot: MLRS_HUMAN, Q96A32
    Tissue specificity: Expressed in fetal and adult skeletal muscle

        SABiosciences Custom PCR Arrays for MYLPF
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYLPF
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYLPF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MYLPF gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mylpf1 , 5 myosin light chain, phosphorylatable, fast skeletal more1, 5 88.76(n)1
    95.86(a)1
      7 (69.39 cM)5
    179071  NM_016754.51  NP_058034.11 
     1272116085 
    lizard
    (Anolis carolinensis)
    Reptilia MYLPF6
    Uncharacterized protein
    62(a)
    1 ↔ 1
    GL343516.1(305626-314174)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.62632 Xenopus laevis mRNA similar to (clone PWHLC2-24) myosin more 81.25(n)    BC053808.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mylz22 myosin, light polypeptide 2, skeletal muscle 82.01(n)   30429  AF081462.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mlc26
    CG330986
    --
    28(a)
    20(a)
    many ↔ many
    many ↔ many
    3R(25997160-26000273)
    3R(8212910-8214517)
    worm
    (Caenorhabditis elegans)
    Secernentea mlc-21 Protein MLC-2 59.3(n)
    50.31(a)
      181775  NM_078427.4  NP_510828.1 


    ENSEMBL Gene Tree for MYLPF (if available)
    TreeFam Gene Tree for MYLPF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MYLPF gene
    MYL12A2  MYL102  MYL72  MYL92  MYL52  MYL22  MYL12B2  
    12 SIMAP similar genes for MYLPF using alignment to 4 protein entries:     MLRS_HUMAN (see all proteins):
    MYL2    MYL5    MYL12A    MRLC3    MYL9    MYL12B
    MYL7    MYL10    CALM2    CALM1    CALML3    CALM3

    MYLPF for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/67 SNPs in MYLPF are shown (see all 67)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs99282181,2
    C,F,H--30384400(+) GATGGG/AAACTA 1 -- us2k113Minor allele frequency- A:0.18NS NA WA CSA 1594
    rs72011801,2
    C,A--30384736(+) gcgggA/Gaaacc 1 -- us2k1 tfbs30--------
    rs1435194251,2
    C--30385234(+) GTGGGA/GGTGGA 1 -- us2k10--------
    rs1882415111,2
    --30385254(+) TCTGCC/TAAAGT 1 -- us2k10--------
    rs118631501,2
    C,F,A,H--30385503(+) GCTTCA/GTGGCA 1 -- us2k127Minor allele frequency- G:0.34NS EA NA WA CSA 2777
    rs1912895481,2
    --30385504(+) CTTCGC/TGGCAC 1 -- us2k10--------
    rs1835942251,2
    --30385511(+) GCACAC/GCTATA 1 -- us2k10--------
    rs2016341381,2
    --30385647(+) AAAAA-/GAGGGA 1 -- us2k10--------
    rs711490101,2
    C--30385648(+) AAAAA-/AGGGAG 1 -- us2k12Minor allele frequency- A:0.25NA 4
    rs80508121,2
    C,F,A,H--30385837(+) CAGAAC/TGATGC 1 -- us2k127Minor allele frequency- T:0.18NS EA MN NA WA CSA 3603

    HapMap Linkage Disequilibrium report for MYLPF (30382255 - 30389312 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MYLPF:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv905724CNV Loss21882294
    nsv905725CNV Loss21882294
    nsv827612CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MYLPF for disorders           About MalaCards

    MYLPF for disorders           About GeneDecksing

    Genetic Association Database (GAD): MYLPF

    Export disorders for MYLPF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MYLPF gene integrated from 9 sources:
    (articles sorted by number of sources associating them with MYLPF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships. (PubMed id 14756420)1, 2 Sachdev S.... Sarkar S. (2003)
    3. Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin. (PubMed id 6179945)1, 3 Garfinkel L.I....Nadal-Ginard B. (1982)
    4. Identification of DeltaNp63alpha protein interactions by mass spectrometry. (PubMed id 20085233)1 Amoresano A....CalabrA^ V. (2010)
    5. An integrated workflow for charting the human interac tion proteome: insights into the PP2A system. (PubMed id 19156129)1 Glatter T....Gstaiger M. (2009)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. Integral and associated lysosomal membrane proteins. (PubMed id 17897319)1 Schroeder B.... Hasilik A. (2007)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The nucleotide sequence of a rat myosin light chain 2 gene. (PubMed id 6091059)1 Nudel U....Levy Z. (1984)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29895 HGNC: 29824 AceView: HUMMLC2B Ensembl:ENSG00000180209 euGenes: HUgn29895
    ECgene: MYLPF Kegg: 29895 H-InvDB: MYLPF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MYLPF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MYLPF gene:
    Search GeneIP for patents involving MYLPF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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