MYLK3 Gene
protein-coding GIFtS: 55
GCID: GC16M046736
|
|
myosin light chain kinase 3
| |
Aliases
for MYLK3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myosin Light Chain Kinase 31 2 | | Cardiac-MyBP-C Associated Ca/CaM Kinase2 | | MLCK1 2 3 5 | | MLC Kinase2 | | CaMLCK1 | | Putative Myosin Light Chain Kinase 32 | | Cardiac-MyBP-C-Associated Ca/CaM Kinase2 3 | | Cardiac-MLCK3 | | MLCK22 | | EC 2.7.11.183 | | Cardiac-MLCK3 | | EC 2.7.118 |
Export aliases for MYLK3 gene to outside databasesPrevious GC identifers: GC16M045293 GC16M032625 |
Summaries
for MYLK3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MYLK3:
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by akinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al.,2008 (PubMed 18202317)).(supplied by OMIM, Jul 2008)
UniProtKB/Swiss-Prot: MYLK3_HUMAN, Q32MK0Function: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increasescardiomyocyte contractility (By similarity)
 summary
for MYLK3: Myosin Light Chain Kinases (MLCKs) are a group of protein serine/threonine kinases that is currently divided
into two subtypes, MLCK1 and MLCK2. MLCK1 is found in smooth muscle and phosphorylates myosin II regulatory
light chains at Ser19, allowing myosin crossbridges to bind to actin filaments and initiate contraction. In
addition to smooth muscle contraction, MLCK1 is involved in a diverse range of biological processes
including control of endothelial and vascular permeability, growth initiation of astrocytes processes,
neurotransmitter release in the sympathetic nervous system and apoptosis of fibroblasts. MLCK2 is found in
striated muscle and co-localizes with phosphorylated MLC filaments to mediate skeletal and cardiac muscle
contraction. MLCK3 and MLCK4 have recently been identified but are yet to be fully characterized. MLCKs are
activated by Ca2+-calmodulin complexes and require Mg2+ or Ca2+ as a co-factor.
Gene Wiki entry for MYLK3
|
Genomic Views
for MYLK3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MYLK3 gene promoter:
Egr-3 GATA-3 SREBP-1c RREB-1 GATA-2 GATA-1 Roaz SREBP-1b SREBP-1a GATA-6
Other transcription factors
Search SABiosciences Chromatin IP Primers for MYLK3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYLK3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q11.2 Ensembl cytogenetic band: 16q11.2 HGNC cytogenetic band: 16q11.2MYLK3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M046736: view genomic region
(about GC identifiers)
Start:
|
46,736,194 bp from pter |
End:
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46,824,319 bp from pter |
Size:
|
88,126 bases |
Orientation:
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minus strand |
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Proteins
for MYLK3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MYLK3_HUMAN, Q32MK0 (See
protein sequence)Recommended Name: Myosin light chain kinase 3 Size: 819 amino acids; 88393 Da
Cofactor: Magnesium (By similarity)
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=AAI09098.2; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=CAC42766.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B5BUL9 B7Z5U8 Q32MK1 Q96DV1Alternative splicing: 2 isoforms: Q32MK0-3 Q32MK0-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MYLK3: NX_Q32MK0
Post-translational modifications:
Phosphorylated on serine residues (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q32MK0
4/6 DME Specific Peptides for MYLK3 (Q32MK0) (see all 6)
MYLK3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_872299.2
ENSEMBL proteins: ENSP00000378288 ENSP00000439297
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MYLK3 for ontologies About GeneDecksing
MYLK3 Antibody Products:
Assay Products for MYLK3: |
Protein
Domains /
Families
for MYLK3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MYLK3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q32MK0ProtoNet protein and cluster: Q32MK0 UniProtKB/Swiss-Prot: MYLK3_HUMAN, Q32MK0Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase familySimilarity: Contains 1 protein kinase domain |
Function
for MYLK3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MYLK3_HUMAN, Q32MK0Function: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increasescardiomyocyte contractility (By similarity)Catalytic activity: ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphateEnzyme Numbers (IUBMB): EC 2.7.112 EC 2.7.11.181
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYLK3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for MYLK3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYLK3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYLK3 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004683 | calmodulin-dependent protein kinase activity |
ISS | -- | | GO:0004687 | myosin light chain kinase activity |
ISS | -- | | GO:0005524 | ATP binding |
IEA | -- |
MYLK3 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for MYLK3:
Animal Models:
Mouse knock-out Mylk3tm1Jtst for MYLK3
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Mylk3):
MYLK3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MYLK3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell adhesion_Integrin-mediated cell adhesion and migration | | | 2 | Immune response _CCR3 signaling in eosinophils | | | 3 | Signal transduction_Activation of PKC via G-Protein coupled receptor | | | 4 | Regulation of Water Balance by Renal Aquaporins | | | 5 | MicroRNAs in cardiomyocyte hypertrophy | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 EMD Millipore Pathways for MYLK3
5/6  GeneGo (Thomson Reuters) Pathways for MYLK3 (see all 6)
1  BioSystems Pathway for MYLK3
5 
Kegg Pathways (Kegg details for MYLK3):
MYLK3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MYLK3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/26 Interacting proteins for MYLK3 (Q32MK03 ENSP000003782884) via UniProtKB, MINT, STRING, and/or I2D (see all 26)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
MYLK3 for ontologies About GeneDecksing
|
Drugs & Compounds
for MYLK3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MYLK3 for compounds About GeneDecksing
Compounds for MYLK3 available from Tocris Bioscience About this table
4 HMDB Compounds for MYLK3 About this table
8 Novoseek chemical compound relationships for MYLK3 gene About this table
Search CenterWatch for drugs/clinical trials and news about MYLK3
|
Transcripts
for MYLK3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MYLK3 gene: NM_182493.2 Unigene Cluster for MYLK3: Myosin light chain kinase 3 Hs.130465 [show with all ESTs]Unigene Representative Sequence: NM_1824937 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000394809(uc002eei.4 uc010vge.2) ENST00000536476 ENST00000565182
ENST00000562104 ENST00000564731(uc002eej.1) ENST00000569844 ENST00000569810
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYLK3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYLK3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MYLK3 (NM_182493) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYLK3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYLK3 |
Additional cDNA sequence: AB451455.1 AJ247087.1 AK299443.1 BC039103.1 BC109096.1 BC109097.1 6 DOTS entries: DT.40313888 DT.101961731 DT.99982217 DT.120721626 DT.100656008 DT.40237473 6 AceView cDNA sequences: Z36720 NM_182493 AJ247087 BC039103 BG719152 BF059578
GeneLoc Exon Structure
|
Expression
for MYLK3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MYLK3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGCCAGGA
About this image
See MYLK3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYLK3
SOURCE GeneReport for Unigene cluster: Hs.130465
UniProtKB/Swiss-Prot: MYLK3_HUMAN, Q32MK0Tissue specificity: Restricted to heart
SABiosciences Expression via Pathway-Focused PCR Array including MYLK3:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYLK3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MYLK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYLK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYLK3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYLK3 |
Orthologs
for MYLK3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MYLK3 gene from 5/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MYLK31 |
myosin light chain kinase 3 |
56.95(n)
53.16(a) |
|
415748 XM_414113.3 XP_414113.3 |
lizard
(Anolis carolinensis) |
Reptilia |
MYLK36 |
-- |
71(a) |
1 ↔ 1 |
LGc(3572078-3586928) |
zebrafish
(Danio rerio) |
Actinopterygii |
mylk36 |
myosin light chain kinase 3 |
38(a) |
1 ↔ 1 |
7(44551781-44587973) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Unc-896sqa6 |
spaghetti-squash activator |
3(a)16(a) |
possible ortholog1 ↔ many |
2R(19883066-19901384) 2R(5603981-5635623) |
worm
(Caenorhabditis elegans) |
Secernentea |
ZC373.46 |
Protein ZC373.4 |
11(a) |
possible ortholog |
X(10062379-10069725) |
ENSEMBL Gene Tree for MYLK3 (if available)
TreeFam Gene Tree for MYLK3 (if available) |
Paralogs
for MYLK3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MYLK3 gene
- STK17B2 DAPK22 MYLK22 TTN2 STK17A2 OBSCN2 DAPK32 SPEG2
- MYLK42 DAPK12 MYLK2 OBSL12
18/30 SIMAP similar genes for MYLK3 using alignment to 2 protein entries: MYLK3_HUMAN (see all proteins)
(see all similar genes):MYLK4 DAPK3 STK17A DAPK2 PRKY STK17B
CAMK2B CAMK1D CAMK4 MYLK2 NUAK1 PRKAA1
STK11 DKFZp564L2416 RPS6KA2 CAMK1 CAMK2D KIN27
MYLK3 for paralogs About GeneDecksing
|
Genomic Variants
for MYLK3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MYLK3 (46736194 - 46824319 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MYLK3: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYLK3 |
|
Disorders
/ Diseases
for MYLK3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MYLK3 for disorders About GeneDecksing
OMIM gene information: 612147
OMIM disorders: --
9  diseases for MYLK3: About MalaCardsinflammatory bowel disease anthrax disease crohn's disease diarrhea
copd fibrosarcoma hypoxia immunodeficiency
alcoholism
3 Novoseek disease relationships for MYLK3 gene About this table
Export disorders for MYLK3 gene to outside databases
|
Publications
for MYLK3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MYLK3 gene, integrated from 9 sources (see all 83):
(articles sorted by number of sources associating them with MYLK3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. (PubMed id 17885681)1, 2, 3 Seguchi O....Kitakaze M. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. (PubMed id 18390750)1, 9 Al-Sadi R....Ma T.Y. (2008)
- Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)1 Toyoshima M....Grandori C. (2012)
- Identification of cardiac-specific myosin light chain kinase. (PubMed id 18202317)1 Chan J.Y....Kasahara H. (2008)
- Human protein factory for converting the transcriptome into an in vitro-expressed proteome. (PubMed id 19054851)2 Goshima N.... Nomura N. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for MYLK3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MYLK3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MYLK3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MYLK3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MYLK3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MYLK3 gene:
Search GeneIP for patents involving MYLK3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MYLK3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MYLK3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYLK3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYLK3 | | | OriGene Protein Over-expression Lysate for MYLK3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MYLK3 | | OriGene 3'-UTR Clone for MYLK3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYLK3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYLK3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MYLK3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYLK3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYLK3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYLK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYLK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYLK3 |
| |
 |  |  |  | |
| | | | Tocris compounds for MYLK3 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | MYLK3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYLK3 |
|  |  |  | | | | ThermoFisher Antibody for MYLK3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYLK3 |
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