Aliases for MYL9 Gene
- Myosin Light Chain 9 2 3 5
- Myosin Regulatory Light Chain 2, Smooth Muscle Isoform 2 3 4
- Myosin, Light Polypeptide 9, Regulatory 2 3
- Myosin Regulatory Light Chain MRLC1 3 4
- Myosin, Light Chain 9, Regulatory 2 3
- Myosin Regulatory Light Chain 1 2 3
- Myosin Regulatory Light Chain 9 3 4
- 20 KDa Myosin Light Chain 3 4
External Ids for MYL9 Gene
Previous GeneCards Identifiers for MYL9 Gene
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYL9 Gene
MYL9 (Myosin Light Chain 9) is a Protein Coding gene. Diseases associated with MYL9 include Primary Cutaneous Amyloidosis. Among its related pathways are CREB Pathway and Smooth Muscle Contraction. GO annotations related to this gene include calcium ion binding and structural constituent of muscle. An important paralog of this gene is MYL12B.
UniProtKB/Swiss-Prot for MYL9 Gene
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins.