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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MYL7 Gene

protein-coding GIFtS: 60
GCID: GC07M044178

myosin, light chain 7, regulatory

(Previous names: myosin, light polypeptide 7, regulatory )

Explore 8 diseases affiliated with
MYL7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Myosin, Light Chain 7, Regulatory¹ ²		Myosin Regulatory Light Chain 7² ³
MYL2A¹ ² ³		MLC-2a² ³
MYLC2A¹ ² ³		MLC2a² ³
Myosin, Light Polypeptide 7, Regulatory¹ ²		Myosin Regulatory Light Chain 2, Atrial Isoform²
Myosin Light Chain 2a² ³

External Ids:	HGNC: 21719¹	Entrez Gene: 58498²	Ensembl: ENSG00000106631⁷	OMIM: 613993⁵	UniProtKB: Q01449³

Export aliases for MYL7 gene to outside databases

Previous GC identifers: GC00U912966 GC07M043919 GC07M043951 GC07M044144 GC07M044063

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

summary for MYL7:

Myosins are a large family of motor proteins that share the common features of ATP hydrolysis, actin binding

and potential for kinetic energy transduction. Originally isolated from muscle cells (hence the name),

almost all eukaryotic cells are now known to contain myosins. Structurally, mysoins contain a head domain

that binds to actin filaments (microfilaments) and is the site of ATP hydrolysis. The tail domain interacts

with cargo molecules, and the neck acts as a linker between the head and tail and is the site of regulatory

myosin light chain binding. There are 17 myosin families and the most well characterized is myosin II.

Myosin II is found predominantly in myocytes and mediates plus-ended movement along microfilaments. It is

involved in muscle contraction through cyclic interactions with actin-rich thin filaments, creating a

contractile force. It is regulated by phosphorylation via myosin light chain kinase (MLCK) and by

intracellular Ca2+ concentrations.

Gene Wiki entry for MYL7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MYL7 gene promoter:
COUP-TF1 COUP-TF COUP HNF-4alpha2 HNF-4alpha1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MYL7 promoter sequence

Search SABiosciences Chromatin IP Primers for MYL7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYL7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21-p11.2 Ensembl cytogenetic band: 7p13 HGNC cytogenetic band: 7p21-p11.2

MYL7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYL7 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M044178: view genomic region (about GC identifiers)

Start:	44,178,463 bp from pter	End:	44,180,931 bp from pter
Size:	2,469 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 44,217,962-44,220,416

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MLRA_HUMAN, Q01449 (See protein sequence)

Recommended Name: Myosin regulatory light chain 2, atrial isoform

Size: 175 amino acids; 19448 Da

Subunit: Myosin is a hexamer of 2 heavy chains and 4 light chains

Miscellaneous: This chain binds calcium

Secondary accessions: B2R4L3

Explore the universe of human proteins at neXtProt for MYL7: NX_Q01449

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q01449

MYL7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_067046.1

ENSEMBL proteins:

ENSP00000416010 ENSP00000223364 ENSP00000403360 ENSP00000389202 ENSP00000403988

ENSP00000399398 ENSP00000411340 ENSP00000404918

Human Recombinant Protein Products for MYL7:

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	ProSpec Recombinant Protein for MYL7
	Uscn Proteins for MYL7

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016459	myosin complex	NAS	1429676
GO:0031672	A band	IDA	15621049
GO:0043197	dendritic spine	IEA	--

MYL7 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for MYL7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MYL7 for domains About GeneDecksing

3 InterPro domains/families:

IPR018247 EF_Hand_1_Ca_BS

IPR011992 EF-hand-like_dom

IPR002048 EF_hand_Ca-bd

Graphical View of Domain Structure for InterPro Entry Q01449

ProtoNet protein and cluster: Q01449

UniProtKB/Swiss-Prot: MLRA_HUMAN, Q01449

Similarity: Contains 3 EF-hand domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000146	microfilament motor activity	NAS	--
GO:0005509	calcium ion binding	NAS	--
GO:0005515	protein binding	--	--
GO:0042623	ATPase activity, coupled	NAS	--

MYL7 for ontologies About GeneDecksing

Phenotypes:
7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Myl7):

cardiovascular system	cellular	embryogenesis	growth/size	homeostasis/metabolism
mortality/aging	muscle

MYL7 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MYL7

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYL7

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/17 super-pathways (see all 17) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Cell adhesion_Integrin-mediated cell adhesion and migration

	Cell adhesion_Integrin-mediated cell adhesion and migration	1.00			Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases	0.49
	Cell adhesion Integrin-mediated cell adhesion and migration	1.00			Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases	0.49

Activation of cAMP-Dependent PKA

	Activation of cAMP-Dependent PKA	1.00			Activation of PKA through GPCR	0.71
	cAMP Pathway	0.77			PKA Signaling	0.56

Immune response _CCR3 signaling in eosinophils

	Immune response _CCR3 signaling in eosinophils	1.00			Inhibitory action of Lipoxins on neutrophil migration	0.51
	Immune response CCR3 signaling in eosinophils	1.00

PAK Pathway

	PAK Pathway	1.00			Epithelial Adherens Junctions	0.36
	Antioxidant Action of Vitamin-C	0.56

Cell adhesion Tight junctions

Cell adhesion Tight junctions

1.00

Cell adhesion_Tight junctions

0.99

Pathway sources
See GeneCards unified pathways
Show all pathways

5 EMD Millipore Pathways for MYL7

	Cell adhesion Integrin-mediated cell adhesion and migration
	Cell adhesion Tight junctions
	Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
	Immune response CCR3 signaling in eosinophils
	Development MAG-dependent inhibition of neurite outgrowth

5/16 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYL7 (see all 16)

	Activation of PKA through GPCR
	RhoA Pathway
	PKA Signaling
	Guidance Cues and Growth Cone Motility
	Antioxidant Action of Vitamin-C

5/6 GeneGo (Thomson Reuters) Pathways for MYL7 (see all 6)

	Cell adhesion Integrin-mediated cell adhesion and migration
	Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
	Inhibitory action of Lipoxins on neutrophil migration
	Immune response CCR3 signaling in eosinophils
	Cell adhesion Tight junctions

4 Kegg Pathways (Kegg details for MYL7):

	Focal adhesion
	Tight junction
	Leukocyte transendothelial migration
	Regulation of actin cytoskeleton

MYL7 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MYL7

STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

5/17 Interacting proteins for MYL7 (Q01449³ ENSP00000223364⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MYH6	P13533³	I2D: score=1
ACTB	ENSP00000349960⁴	STRING: ENSP00000349960
ACTG1	ENSP00000331514⁴	STRING: ENSP00000331514
CGN	ENSP00000271636⁴	STRING: ENSP00000271636
MYH10	ENSP00000269243⁴	STRING: ENSP00000269243

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006939	smooth muscle contraction	NAS	--
GO:0030048	actin filament-based movement	NAS	--

MYL7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for MYL7 available from Tocris Bioscience About this table

Compound	Action	CAS #
(R)-(+)-Blebbistatin	Selective inhibitor of myosin II. Inactive enantiomer of (�)-blebbistatin (Cat. No. 1760)	--
(S)-(-)-Blebbistatin	Selective inhibitor of myosin II. Active enantiomer of (�)-blebbistatin (Cat. No. 1760)	[856925-71-8]
(�)-Blebbistatin	Selective inhibitor of myosin II	[674289-55-5]

1 HMDB Compound for MYL7 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

Search CenterWatch for drugs/clinical trials and news about MYL7 / MLRA

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MYL7 gene:

NM_021223.2

Unigene Cluster for MYL7:

Myosin, light chain 7, regulatory

Hs.75636 [show with all ESTs]

Unigene Representative Sequence: BI836837

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000446581 ENST00000223364(uc003tkg.3) ENST00000458240 ENST00000434895

ENST00000457314 ENST00000447951 ENST00000476118 ENST00000431289 ENST00000431007

ENST00000457910

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYL7
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		GenScript: all cDNA clones in your preferred vector: MYL7 (NM_021223)
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Additional cDNA sequence:

AK311869.1 BC027915.1 M94547.1

20 DOTS entries:

DT.450936 DT.91660291 DT.95084864 DT.87078096 DT.100754736 DT.100754737 DT.121061744 DT.91660254

DT.95371985 DT.95372000 DT.121061729 DT.95371983 DT.40292489 DT.102826012 DT.121061722 DT.121061728

DT.91660294 DT.95371995 DT.95371996 DT.121061740

24/335 AceView cDNA sequences (see all 335):

AA249277 BC027915 AA247745 AJ709502 T28710 N86069 NM_021223 BQ445851

N86275 C05145 AA347095 AA248626 AA247462 AJ708771 BX501516 AJ712021

AA346344 AA247791 AJ710773 AI332570 AJ711909 AA248691 AJ706807 AI355734

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for MYL7 (see all 8) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3a	·	3b	·	3c	^	4	^	5	^	6a	·	6b	^	7
SP1:													-		-								-				-
SP2:									-				-		-								-				-
SP3:													-		-								-		-		-
SP4:													-		-												-
SP5:									-				-

ECgene alternative splicing isoforms for MYL7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MYL7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGACGAGAA

About this image

MYL7 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10/14 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 14)

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Cardiac Crescent

Cardiac Crescent Cells

Selective marker (cell-identifying gene)

Myocardium

Myocardium

Myocardium

Myocardium

Myocardium

Myocardium

Primitive Heart Tube Cells

Myocardium

Myocardium

Myocardium

Epicardium

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 9 LifeMap Cells

Name

Category

Cardiomyocyte-like cells (Cardiomyocyte genera...)

Cardiac mesoderm embryoid bodies (Cardiomyocyte genera...)

Cardiomyocyte-like progenitor cells (Derivation of cardio...)

DKK1-induced cells (Derivation of cardio...)

Cardiomyocyte-like cells (Spontaneous differen...)

Mesoderm-like cells (Derivation of cardio...)

Definitive endoderm-like cells (Generation of mesend...)

Posterior foregut-like cells (A scalable, suspensi...)

Definitive Endoderm (Generation of beta c...)

See MYL7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYL7

SOURCE GeneReport for Unigene cluster: Hs.75636

UniProtKB/Swiss-Prot: MLRA_HUMAN, Q01449

Tissue specificity: Predominantly expressed in adult atrial muscle

SABiosciences Custom PCR Arrays for MYL7

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYL7

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYL7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for MYL7 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
African clawed frog (Xenopus laevis)	Amphibia	mylc2a-prov²	myosin light chain, regulatory A	79.41(n)		Z33999.1
zebrafish (Danio rerio)	Actinopterygii	mylc2a²	myosin light chain, regulatory A	75.19(n)		30592 AY057074.1
fruit fly (Drosophila melanogaster)	Insecta	Mlc2⁶ Eip63F-1⁶ (see all 3)	Ecdysone-induced protein 63F 1 (see all 3)	28(a) 18(a) (see all 3)	possible ortholog possible ortholog (see all 3)	3R(25997160-26000273) 3L(3909973-3935617)
worm (Caenorhabditis elegans)	Secernentea	mlc-2⁶ mlc-1⁶	Myosin regulatory light chain 1	41(a) 41(a)	many ↔ many many ↔ many	X(17455705-17456520) X(17459086-17460693)
rice (Oryza sativa)	Liliopsida	--	OsCML9 - Calmodulin-related calcium sensor protein...	21(a)	possible ortholog	5(24067532-24068539)

ENSEMBL Gene Tree for MYL7 (if available)
TreeFam Gene Tree for MYL7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MYL7 gene

MYL12A² MYL10² MYL9² MYL5² MYL2² MYLPF² MYL12B²

13 SIMAP similar genes for MYL7 using alignment to 8 protein entries: MLRA_HUMAN (see all proteins):

MYL5 MYLPF MYL12A MYL2 MYL9 MRLC3

MYL12B MYL10 CALM3 CALM2 CALM1 CALML3

CALML4

MYL7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs187876042^1,2		--	44177973(+)	`AAAGGA/GCCCAT`	1	--	int¹		0	--	--	--	--
rs111353978^1,2		--	44178088(+)	`GGGCTA/G/TTTGGG`	1	--	int¹		2		CSA	3
rs139668933^1,2		--	44178343(+)	`CTGGCA/GAGGGG`	1	--	int¹		0	--	--	--	--
rs79902400^1,2	C,F	--	44178393(+)	`ATGTGC/TGCACT`	1	--	int¹		1		NA	120
rs192675893^1,2		--	44178402(+)	`CTGAGA/GCCCTG`	1	--	int¹		0	--	--	--	--
rs184501880^1,2		--	44178462(+)	`CAGCAA/GTTCCA`	1	--	spd¹		0	--	--	--	--
rs75018391^1,2	C	--	44178498(+)	`GCCCCA/C/GCCGTG`	2	--	ut3¹		1		WA	118
rs141852636^1,2	F	--	44178535(+)	`TTCTCG/ATCTCC`	2	/D	syn¹		1		NA	4552
rs150622990^1,2	C,F	--	44178576(+)	`GTCGAT/CGTTCC`	2	/I /V	mis¹		1		NA	4552
rs138710066^1,2	C	--	44178583(+)	`TTCCCC/G/TGCCAG`	3	A	syn¹		1		NA	4552

HapMap Linkage Disequilibrium report for MYL7 (44178463 - 44180931 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MYL7
1 CNV: 4532

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MYL7 for disorders           About GeneDecksing

OMIM gene information: 613993    OMIM disorders: --

8 diseases for MYL7:    About MalaCards

hypertrophic cardiomyopathy endometritis embryonal carcinoma down syndrome

cardiomyopathy hermaphroditism pharyngitis carcinoma

1 disease from the University of Copenhagen DISEASES database for MYL7:

Endometritis

Export disorders for MYL7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MYL7 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with MYL7)

Utopia: connect your pdf to the dynamic
world of online information

Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. (PubMed id 8207020)^{1, 3, 9} Kubalak S.W....Chien K.R. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development. (PubMed id 1429676)^{1, 2} Hailstones D.L.... Gunning P.W. (1992)
Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain en dothelial cells. (PubMed id 19794400)¹ Zhong Y....Toborek M. (2010)
[Expression and function of non-muscle myosin-IIA in Fechtner syndrome] (PubMed id 18718080)¹ Yang H.Y....Ruan C.G. (2008)
Mutation in myosin heavy chain 6 causes atrial septal defect. (PubMed id 15735645)¹ Ching Y.-H.... Brook J.D. (2005)
Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium. (PubMed id 15621049)¹ Grimm M....Eschenhagen T. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform. (PubMed id 12847096)¹ Kovacs M....Sellers J.R. (2003)
The human adult cardiomyocyte phenotype. (PubMed id 12757876)¹ Bird S.D....Mummery C.L. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 58498	HGNC: 21719	AceView: MYL7	Ensembl:ENSG00000106631	euGenes: HUgn58498
ECgene: MYL7	Kegg: 58498	H-InvDB: MYL7

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MYL7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MYL7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MYL7 gene:
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GeneCards and IP:
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myosin, light chain 7, regulatory

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MYL7 Gene

myosin, light chain 7, regulatory

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