Aliases for MYL4 Gene
External Ids for MYL4 Gene
Previous GeneCards Identifiers for MYL4 Gene
Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYL4 Gene
MYL4 (Myosin, Light Chain 4, Alkali; Atrial, Embryonic) is a Protein Coding gene. Diseases associated with MYL4 include congenital disorder of glycosylation, type iid and aortic valve disease 2. Among its related pathways are RhoGDI Pathway and Activation of cAMP-Dependent PKA. GO annotations related to this gene include calcium ion binding and actin monomer binding. An important paralog of this gene is MYL1.
UniProtKB/Swiss-Prot for MYL4 Gene
Regulatory light chain of myosin. Does not bind calcium
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins.