Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MYH9 Gene

protein-coding   GIFtS: 72
GCID: GC22M036677

myosin, heavy chain 9, non-muscle

(Previous names: myosin, heavy polypeptide 9, non-muscle )
(Previous symbol: DFNA17)
 Explore 60 diseases affiliated with
MYH9 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MYH9    

Aliases
for MYH9 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Myosin, Heavy Chain 9, Non-Muscle1 2     Non-Muscle Myosin Heavy Chain A2 3
DFNA171 2 5     Non-Muscle Myosin Heavy Chain IIa2 3
FTNS1 2 5     NMMHC-IIA2 3
MHA1 2 5     Myosin, Heavy Polypeptide 9, Non-Muscle1
EPSTS1 2     BDPLT62
NMHC-II-A1 2     Myosin-91
NMMHCA1 2     Non-Muscle Myosin Heavy Polypeptide 92
Cellular Myosin Heavy Chain, Type A2 3     Nonmuscle Myosin Heavy Chain II-A2
Myosin Heavy Chain 92 3     NMMHC-A3
Myosin Heavy Chain, Non-Muscle IIa2 3     NMMHC II-A3

External Ids:    HGNC: 75791   Entrez Gene: 46272   Ensembl: ENSG000001003457   OMIM: 1607755   UniProtKB: P355793   

Export aliases for MYH9 gene to outside databases

Previous GC identifers: GC22M033322 GC22M034949 GC22M035001 GC22M019645


Summaries
for MYH9 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MYH9:
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional
myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a
myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and
maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness
autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner
syndrome and macrothrombocytopenia with progressive sensorineural deafness. (provided by RefSeq, Dec 2011)

UniProtKB/Swiss-Prot: MYH9_HUMAN, P35579
Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as
secretion and capping

summary for MYH9:
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis, actin binding
and potential for kinetic energy transduction. Originally isolated from muscle cells (hence the name),
almost all eukaryotic cells are now known to contain myosins. Structurally, mysoins contain a head domain
that binds to actin filaments (microfilaments) and is the site of ATP hydrolysis. The tail domain interacts
with cargo molecules, and the neck acts as a linker between the head and tail and is the site of regulatory
myosin light chain binding. There are 17 myosin families and the most well characterized is myosin II.
Myosin II is found predominantly in myocytes and mediates plus-ended movement along microfilaments. It is
involved in muscle contraction through cyclic interactions with actin-rich thin filaments, creating a
contractile force. It is regulated by phosphorylation via myosin light chain kinase (MLCK) and by
intracellular Ca2+ concentrations.

Gene Wiki entry for MYH9


Genomic Views
for MYH9 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011520.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYH9 gene promoter:
         Max1   USF1   MyoD   Tal-1beta   E47   c-Ets-1   USF-1   Cart-1   Pax-4a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): MYH9 promoter sequence
   Search SABiosciences Chromatin IP Primers for MYH9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYH9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q12.3   HGNC cytogenetic band: 22q13.1

MYH9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYH9 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M036677:  view genomic region     (about GC identifiers)

Start:
 36,677,323 bp from pter      End:
 36,784,063 bp from pter
Size:
 106,741 bases      Orientation:
 minus strand

Proteins
for MYH9 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MYH9_HUMAN, P35579 (See protein sequence)
Recommended Name: Myosin-9  
Size: 1960 amino acids; 226532 Da
Subunit: Interacts with PDLIM2 (By similarity). Interacts with SLC6A4 (By similarity). Myosin is a hexameric protein
that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain
subunits (MLC-2). Interacts with RASIP1. Interacts with DDR1 (By similarity). Interacts with SVIL and HTRA3
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cytoplasm, cell cortex (By similarity). Note=Colocalizes
with actin filaments at lamellipodia margins and at the leading edge of migrating cells (By similarity)
Sequence caution: Sequence=CAD89954.1; Type=Frameshift; Positions=1890;
3 PDB 3D structures from and Proteopedia for MYH9:
2LNK (3D)        3ZWH (3D)        4ETO (3D)    
Secondary accessions: O60805 Q86T83
Alternative splicing: 2 isoforms:  P35579-1   P35579-2   

Explore the universe of human proteins at neXtProt for MYH9: NX_P35579

Post-translational modifications:

  • ISGylated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P35579

    • MYH9 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002464.1  
    ENSEMBL proteins: 
     ENSP00000216181   ENSP00000384631   ENSP00000414852  
    Reactome Protein details: P35579
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for MYH9 
    GenScript Custom Purified and Recombinant Proteins Services for MYH9
    Novus Biologicals MYH9 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MYH9

    Gene Ontology (GO): 5/23 cellular component terms (GO ID links to tree view) (see all 23):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001725stress fiber IDA15774463
    GO:0001726ruffle IDA16403913
    GO:0001772colocalizes with immunological synapse IDA15064761
    GO:0001931uropod IDA15064761
    GO:0005634nucleus IDA14508515


    MYH9 for ontologies           About GeneDecksing



    MYH9 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of MYH9
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for MYH9 
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MYH9 
    GenScript Custom Superior Antibodies Services for MYH9
    Novus Biologicals MYH9 Antibodies
    Abcam antibodies for MYH9 
    Uscn Antibodies for MYH9
    ThermoFisher Antibody for MYH9

    Assay Products for MYH9: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MYH9
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for MYH9

    Protein Domains /
    Families
    for MYH9 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MYH9 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR004009 Myosin_N
     IPR000048 IQ_motif_EF-hand-BS
     IPR002928 Myosin_tail
     IPR016137 Regulat_G_prot_signal_superfam
     IPR001609 Myosin_head_motor_dom

    Graphical View of Domain Structure for InterPro Entry P35579

    ProtoNet protein and cluster: P35579

    4 Blocks protein families:
    IPB000048 IQ calmodulin-binding region
    IPB002017 Spectrin repeat
    IPB002928 Myosin tail
    IPB004009 Myosin N-terminal SH3-like domain


    UniProtKB/Swiss-Prot: MYH9_HUMAN, P35579
    Domain: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4
    heptapeptides, characteristic for alpha-helical coiled coils
    Similarity: Contains 1 IQ domain
    Similarity: Contains 1 myosin head-like domain


    Function
    for MYH9 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MYH9_HUMAN, P35579
    Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as
    secretion and capping

         Genatlas biochemistry entry for MYH9:
    myosin,motor contractile protein moving towards the "plus" end of actin track,heavy polypeptide 9,non muscle

    miRNA
    Products:            		miRTarBase miRNAs that target MYH9:
    hsa-mir-124 (MIRT002579)

    OriGene 3'-UTR Clone: MYH9
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYH9
    8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate MYH9 (see all 47):
    hsa-miR-194* hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-300 hsa-miR-376b hsa-miR-25 hsa-miR-449a hsa-miR-10b*
    SwitchGear 3'UTR luciferase reporter plasmid: MYH9 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYH9 (see all 7)
    OriGene shRNA RFP: MYH9
    OriGene siRNA: MYH9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYH9

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for MYH9

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYH9 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYH9
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MYH9 (NM_002473)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYH9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYH9 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for MYH9
    Search LifeMap BioReagents cell lines for MYH9

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYH9

    Gene Ontology (GO): 5/12 molecular function terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000146microfilament motor activity IDA15845534
    GO:0003774motor activity NAS12421915
    GO:0003779actin binding IDA15065866
    GO:0005515protein binding IPI16403913
    GO:0005516calmodulin binding IEA--


    MYH9 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for MYH9:
     Increased focal adhesion (FA)   Large cells 

    Animal Models:
         Mouse knock-out Myh9tm1Maco for MYH9
         13 MGI mutant phenotypes (inferred from 11 alleles) (MGI details for Myh9):
     cardiovascular system  cellular  embryogenesis  growth/size  hearing/vestibular/ear 
     hematopoietic system  homeostasis/metabolism  immune system  mortality/aging  nervous system 
     no phenotypic analysis  normal  renal/urinary system 

    MYH9 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for MYH9 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/19 super-pathways (see all 19) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell adhesion_Integrin-mediated cell adhesion and migration
    		Cell adhesion_Integrin-mediated cell adhesion and migration1.00
    		Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    		Cell adhesion Integrin-mediated cell adhesion and migration1.00
    		Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases0.49
    2Immune response _CCR3 signaling in eosinophils
    		Immune response _CCR3 signaling in eosinophils1.00
    		Inhibitory action of Lipoxins on neutrophil migration0.51
    		Immune response CCR3 signaling in eosinophils1.00
    3Regulation of actin dynamics for phagocytic cup formation
    		Regulation of actin dynamics for phagocytic cup formation1.00
    		Fcgamma receptor (FCGR) dependent phagocytosis0.80
    		Role of myosins in phagosome formation0.80
    4PAK Pathway
    		PAK Pathway1.00
    		Epithelial Adherens Junctions0.36
    		Antioxidant Action of Vitamin-C0.56
    5Sema4D in semaphorin signaling
    		Sema4D in semaphorin signaling1.00
    		Semaphorin interactions0.44
    		Sema4D induced cell migration and growth-cone collapse0.83

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5 EMD Millipore Pathways for MYH9
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cell adhesion Tight junctions
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Immune response CCR3 signaling in eosinophils
    Development MAG-dependent inhibition of neurite outgrowth

    5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYH9 (see all 11)
        RhoA Pathway
    Antioxidant Action of Vitamin-C
    Transendothelial Migration of Leukocytes
    Actin Nucleation by ARP-WASP Complex
    Epithelial Adherens Junctions

    1 Cell Signaling Technology (CST) Pathway for MYH9
        Cytoskeletal Signaling

    5/6 GeneGo (Thomson Reuters) Pathways for MYH9 (see all 6)
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Inhibitory action of Lipoxins on neutrophil migration
    Immune response CCR3 signaling in eosinophils
    Cell adhesion Tight junctions

    5/10        Reactome Pathways for MYH9 (see all 10)
        Developmental Biology
    Role of myosins in phagosome formation
    Fcgamma receptor (FCGR) dependent phagocytosis
    Semaphorin interactions
    Sema4D induced cell migration and growth-cone collapse


    3         Kegg Pathways  (Kegg details for MYH9):
        Tight junction
    Regulation of actin cytoskeleton
    Viral myocarditis


    MYH9 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MYH9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    896/953 Interacting proteins for MYH9 (P355791, 2, 3 ENSP000002161814) via UniProtKB, MINT, STRING, and/or I2D (see all 953) (see top 5)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCLP193381, 2, 3, ENSP000003181954EBI-1054343,EBI-352553 MINT-7945693 I2D: score=2 STRING: ENSP00000318195
    ACTBP607092, 3, ENSP000003499604MINT-7945693 MINT-7899812 MINT-7900157 MINT-7947479 I2D: score=4 STRING: ENSP00000349960
    HSP90AB1P082382, 3MINT-7945693 MINT-72662 MINT-7947479 I2D: score=3 
    CALM1P621582, 3MINT-7899812 I2D: score=1 
    CALM2P621582, 3MINT-7899812 I2D: score=1 
    CALM3P621582, 3MINT-7899812 I2D: score=1 
    COPS5Q929052, 3, ENSP000003505124MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000350512
    LMNAP025452, 3MINT-7945693 MINT-7899812 MINT-7947479 I2D: score=1 
    YWHAQP273482, 3, ENSP000002380814MINT-7899812 MINT-7900157 I2D: score=1 STRING: ENSP00000238081
    ACTG1P632612, 3, ENSP000003315144MINT-7899812 I2D: score=4 STRING: ENSP00000331514
    CHUKO151112, 3, ENSP000003594244MINT-48057 I2D: score=2 STRING: ENSP00000359424
    TNFRSF1AP194382, 3, ENSP000001627494MINT-49353 I2D: score=2 STRING: ENSP00000162749
    TUFMP494112, 3, ENSP000003224394MINT-7945693 I2D: score=2 STRING: ENSP00000322439
    ATG9AQ7Z3C62, 3, ENSP000003551734MINT-8142033 I2D: score=1 STRING: ENSP00000355173
    CCT3P493682, 3MINT-7945693 MINT-7947479 I2D: score=1 
    DIAPH1O606102, 3MINT-7945693 MINT-7947479 I2D: score=1 
    DNAJA1P316892, 3MINT-7945693 MINT-7947479 I2D: score=1 
    HSP90AA1P079002, 3MINT-7945693 MINT-7947479 I2D: score=1 
    PLK1P533502, 3MINT-7945693 MINT-7947479 I2D: score=1 
    RUVBL2Q9Y2302, 3MINT-7945693 MINT-7947479 I2D: score=1 
    ASCC2Q9H1I82, 3MINT-65474 I2D: score=5 
    IKBKEQ141642, 3MINT-48117 I2D: score=2 
    IKBKGQ9Y6K92, 3MINT-48214 I2D: score=2 
    MAP3K3Q997592, 3MINT-48485 I2D: score=2 
    PWP1Q136102, 3MINT-7945693 I2D: score=2 
    RIPK2O433532, 3MINT-49070 I2D: score=2 
    TNFRSF1BP203332, 3MINT-49443 I2D: score=2 
    EIF2S2P200422, 3MINT-7945693 I2D: score=1 
    PRKAG1P546192, 3MINT-7945693 I2D: score=1 
    SEPT7Q161812, 3MINT-7945693 I2D: score=1 
    TTNQ8WZ422, 3MINT-7899812 I2D: score=1 
    YWHABP319462, 3MINT-7900157 I2D: score=1 
    YWHAGP619812, 3MINT-7899812 I2D: score=1 
    YWHAZP631042, 3, ENSP000003095034MINT-7899812 MINT-7900157 I2D: score=2 STRING: ENSP00000309503
    ROCK2O751162, ENSP000003179854MINT-7945693 MINT-7947479 STRING: ENSP00000317985
    CXCR4P610731, 3, ENSP000003868844EBI-1054343,EBI-489411 I2D: score=3 STRING: ENSP00000386884
    MEN1O002551, 3, ENSP000003370884EBI-1054343,EBI-592789 I2D: score=3 STRING: ENSP00000337088
    TRPM7Q96QT42, 3, ENSP000003202394MINT-6699369 I2D: score=3 STRING: ENSP00000320239
    CBLP226812, 3, ENSP000002640334MINT-7899812 I2D: score=1 STRING: ENSP00000264033
    TRPM6Q9BX842, 3, ENSP000003540064MINT-6699553 I2D: score=1 STRING: ENSP00000354006
    SUMO1P631652, 3, ENSP000003760764MINT-7947479 I2D: score=1 STRING: ENSP00000376076
    MYH7P128832, ENSP000003475074MINT-7899812 MINT-7900157 STRING: ENSP00000347507
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    NFKB1P198382, 3, ENSP000002265744MINT-48678 I2D: score=1 STRING: ENSP00000226574
    EEF1A1P681042MINT-7945693 MINT-7900157 MINT-7947479
    HNRNPA2B1P226262MINT-7945693 MINT-7899812 MINT-7947479
    HNRNPCP079102MINT-7945693 MINT-7899812 MINT-7947479
    HSPB1P047922MINT-7945693 MINT-7900157 MINT-7947479
    MYH13Q9UKX32, ENSP000002521724MINT-7899812 MINT-7900157 STRING: ENSP00000252172
    MYL3P085902, ENSP000002923274MINT-7899812 MINT-7900157 STRING: ENSP00000292327
    PRKDCP785272MINT-7945693 MINT-7900157 MINT-7947479
    RALYQ9UKM92MINT-7945693 MINT-7899812 MINT-7947479
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    SPTAN1Q138132MINT-7945693 MINT-7902300 MINT-7947479
    VIMP086702MINT-7945693 MINT-7899812 MINT-7947479
    YWHAEP622582MINT-7899812 MINT-7900157 MINT-7947479
    GRB2P629933, ENSP000003390074I2D: score=3 STRING: ENSP00000339007
    S100A4P264473, ENSP000003462944I2D: score=3 STRING: ENSP00000346294
    AGO3Q9H9G73, ENSP000003622874I2D: score=2 STRING: ENSP00000362287
    APPP050673, ENSP000002849814I2D: score=2 STRING: ENSP00000284981
    MYOM1P521793, ENSP000003488214I2D: score=2 STRING: ENSP00000348821
    PRKCEQ021563, ENSP000003061244I2D: score=2 STRING: ENSP00000306124
    PTPN6P293503, ENSP000003915924I2D: score=2 STRING: ENSP00000391592
    USP1O947823, ENSP000003435264I2D: score=2 STRING: ENSP00000343526
    CD163Q86VB73, ENSP000003520714I2D: score=1 STRING: ENSP00000352071
    CREBBPQ927933, ENSP000002623674I2D: score=1 STRING: ENSP00000262367
    ESR1P033723, ENSP000002062494I2D: score=1 STRING: ENSP00000206249
    HDAC5Q9UQL63, ENSP000002259834I2D: score=1 STRING: ENSP00000225983
    MARK4Q96L343, ENSP000003008434I2D: score=1 STRING: ENSP00000300843
    MYOM2P542963, ENSP000002621134I2D: score=1 STRING: ENSP00000262113
    PPP2R4Q152573, ENSP000003518854I2D: score=1 STRING: ENSP00000351885
    RHOAP615863, ENSP000004001754I2D: score=1 STRING: ENSP00000400175
    TRAF4Q9BUZ43, ENSP000002623954I2D: score=1 STRING: ENSP00000262395
    UBE3AQ050863, ENSP000003810454I2D: score=1 STRING: ENSP00000381045
    SVILO954253, ENSP000003481284I2D: score=1 STRING: ENSP00000348128
    USP45Q70EL23, ENSP000003333764I2D: score=2 STRING: ENSP00000333376
    CCR5P516813, ENSP000002923034I2D: score=1 STRING: ENSP00000292303
    MYBPC3Q148963, ENSP000003821934I2D: score=2 STRING: ENSP00000382193
    MYH10P355803, ENSP000002692434I2D: score=2 STRING: ENSP00000269243
    OVGP1Q128893, ENSP000003587474I2D: score=1 STRING: ENSP00000358747
    S100PP258153, ENSP000002963704I2D: score=1 STRING: ENSP00000296370
    TRAF3IP1Q8TDR03, ENSP000003624244I2D: score=1 STRING: ENSP00000362424
    GRIN1Q055863, ENSP000003606164I2D: score=3 STRING: ENSP00000360616
    RAC1P630003, ENSP000003484614I2D: score=3 STRING: ENSP00000348461
    TERF1P542743, ENSP000002766034I2D: score=1 STRING: ENSP00000276603
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    WNK1Q9H4A33, ENSP000003130594I2D: score=2 STRING: ENSP00000313059
    EPB41P111713, ENSP000002901004I2D: score=2 STRING: ENSP00000290100
    MYL9P248443, ENSP000002790224I2D: score=3 STRING: ENSP00000279022
    NCOA3Q9Y6Q93, ENSP000003610664I2D: score=1 STRING: ENSP00000361066
    ABCF1Q8NE712MINT-7945693 MINT-7947479
    ABCF3Q9NUQ82MINT-7945693 MINT-7947479
    ACTA2P627362MINT-7899812 MINT-7900157
    ACTL6AO960192MINT-7945693 MINT-7947479
    ACTR1AP611632MINT-7945693 MINT-7947479
    ACTR2P611602MINT-7945693 MINT-7947479
    ADNPQ9H2P02MINT-7945693 MINT-7947479
    AHNAKQ096662MINT-7945693 MINT-7947479
    ANAPC1Q9H1A42MINT-7945693 MINT-7947479
    ANKRD18AQ8IVF62MINT-7899812 MINT-7900157
    ANLNQ9NQW62MINT-7945693 MINT-7947479
    AP1B1Q105672MINT-7945693 MINT-7947479
    ARCN1P484442MINT-7945693 MINT-7947479
    ARHGEF1Q928882MINT-7945693 MINT-7947479
    ARHGEF2Q929742MINT-7945693 MINT-7947479
    ARID1AO144972MINT-7945693 MINT-7947479
    ATP5A1P257052MINT-7899812 MINT-7900157
    AURKBQ96GD42MINT-7945693 MINT-7947479
    BAZ1AQ9NRL22MINT-7945693 MINT-7947479
    BCAS2O759342MINT-7945693 MINT-7947479
    BCLAF1Q9NYF82MINT-7945693 MINT-7947479
    BRD8Q9H0E92MINT-7945693 MINT-7947479
    BTAF1O149812MINT-7945693 MINT-7947479
    BUB1O436832MINT-7945693 MINT-7947479
    BUB1BO605662MINT-7945693 MINT-7947479
    BUB3O436842MINT-7945693 MINT-7947479
    BZW1Q7L1Q62MINT-7945693 MINT-7947479
    C22orf28Q9Y3I02MINT-7945693 MINT-7947479
    CAPGP401212MINT-7945693 MINT-7947479
    CAPZA1P529072MINT-7945693 MINT-7947479
    CCNB1P146352MINT-7945693 MINT-7947479
    CCT2P783712MINT-7945693 MINT-7947479
    CCT4P509912MINT-7945693 MINT-7947479
    CCT5P486432MINT-7945693 MINT-7947479
    CCT6AP402272MINT-7945693 MINT-7947479
    CCT7Q998322MINT-7945693 MINT-7947479
    CCT8P509902MINT-7945693 MINT-7947479
    CDC16Q130422MINT-7945693 MINT-7947479
    CDC23Q9UJX22MINT-7945693 MINT-7947479
    CDC27P302602MINT-7945693 MINT-7947479
    CDC73Q6P1J92MINT-7945693 MINT-7947479
    CDK9P507502MINT-7945693 MINT-7947479
    CDKN2AIPQ9NXV62MINT-7945693 MINT-7947479
    CHD1LQ86WJ12MINT-7945693 MINT-7947479
    CHD8Q9HCK82MINT-7945693 MINT-7947479
    CHEK1O147572MINT-7945693 MINT-7947479
    CKAP5Q140082MINT-7945693 MINT-7947479
    COPAP536212MINT-7945693 MINT-7947479
    COPB1P536182MINT-7945693 MINT-7947479
    COPB2P356062MINT-7945693 MINT-7947479
    COPG1Q9Y6782MINT-7945693 MINT-7947479
    COPG2Q9UBF22MINT-7945693 MINT-7947479
    CPSF2Q9P2I02MINT-7945693 MINT-7947479
    CPSF3Q9UKF62MINT-7945693 MINT-7947479
    CPSF7Q8N6842MINT-7945693 MINT-7947479
    CSE1LP550602MINT-7945693 MINT-7947479
    CSTF3Q129962MINT-7945693 MINT-7947479
    CUL1Q136162MINT-7945693 MINT-7947479
    DCTN2Q135612MINT-7945693 MINT-7947479
    DDX17Q928412MINT-7945693 MINT-7947479
    DDX19AQ9NUU72MINT-7945693 MINT-7947479
    DDX19BQ9UMR22MINT-7945693 MINT-7947479
    DDX39AO001482MINT-7945693 MINT-7947479
    DDX39BQ138382MINT-7945693 MINT-7947479
    DDX3XO005712MINT-7945693 MINT-7947479
    DDX41Q9UJV92MINT-7945693 MINT-7947479
    DDX42Q86XP32MINT-7945693 MINT-7947479
    DDX5P178442MINT-7945693 MINT-7947479
    DEPDC7Q96QD52MINT-7945693 MINT-7947479
    DFNA5O604432MINT-7945693 MINT-7947479
    DIDO1Q9BTC02MINT-7945693 MINT-7947479
    DMAP1Q9NPF52MINT-7945693 MINT-7947479
    DNM1LO004292MINT-7945693 MINT-7947479
    DNM2P505702MINT-7945693 MINT-7947479
    DRG1Q9Y2952MINT-7945693 MINT-7947479
    DSPP159242MINT-7945693 MINT-7947479
    DYNC1H1Q142042MINT-7945693 MINT-7947479
    DYNC1LI2O432372MINT-7945693 MINT-7947479
    EFTUD2Q150292MINT-7945693 MINT-7947479
    EHD1Q9H4M92MINT-7945693 MINT-7947479
    EHD4Q9H2232MINT-7945693 MINT-7947479
    EIF2S3P410912MINT-7945693 MINT-7947479
    EIF3GO758212MINT-7945693 MINT-7947479
    EIF3IQ133472MINT-7945693 MINT-7947479
    EIF4A1P608422MINT-7945693 MINT-7947479
    EIF4A3P389192MINT-7945693 MINT-7947479
    EIF4G2P783442MINT-7945693 MINT-7947479
    EIF5BO608412MINT-7945693 MINT-7947479
    ELAVL1Q157172MINT-7945693 MINT-7947479
    ENAHQ8N8S72MINT-7945693 MINT-7947479
    ENSG00000266714Q96JP22MINT-7945693 MINT-7947479
    EPPK1P581072MINT-7945693 MINT-7947479
    EPS8L2Q9H6S32MINT-7945693 MINT-7947479
    ETF1P624952MINT-7945693 MINT-7947479
    ETV6P412122MINT-7945693 MINT-7947479
    EXOC2Q96KP12MINT-7945693 MINT-7947479
    EXOC4Q96A652MINT-7945693 MINT-7947479
    EXOC5O004712MINT-7945693 MINT-7947479
    EXOC7Q9UPT52MINT-7945693 MINT-7947479
    EXOSC10Q017802MINT-7945693 MINT-7947479
    FAM129BQ96TA12MINT-7945693 MINT-7947479
    FANCIQ9NVI12MINT-7945693 MINT-7947479
    FASNP493272MINT-7945693 MINT-7947479
    FEN1P397482MINT-7945693 MINT-7947479
    FERMT1Q9BQL62MINT-7945693 MINT-7947479
    FHOD1Q9Y6132MINT-7945693 MINT-7947479
    FUSP356372MINT-7945693 MINT-7947479
    GATAD2AQ86YP42MINT-7945693 MINT-7947479
    GCN1L1Q926162MINT-7945693 MINT-7947479
    GEMIN4P576782MINT-7945693 MINT-7947479
    GTF2IP783472MINT-7945693 MINT-7947479
    GTF3C2Q8WUA42MINT-7945693 MINT-7947479
    GULP1Q9UBP92MINT-7945693 MINT-7947479
    H1F0P073052MINT-7899812 MINT-7900157
    HBS1LQ9Y4502MINT-7945693 MINT-7947479
    HDAC1Q135472MINT-7945693 MINT-7947479
    HDAC2Q927692MINT-7945693 MINT-7947479
    HDLBPQ003412MINT-7945693 MINT-7947479
    HELLSQ9NRZ92MINT-7945693 MINT-7947479
    HIP1RO751462MINT-7945693 MINT-7947479
    HIRAP541982MINT-7945693 MINT-7947479
    HIST1H2BDP588762MINT-7899812 MINT-7900157
    HIST1H4AP628052MINT-7899812 MINT-7900157
    HIST1H4BP628052MINT-7899812 MINT-7900157
    HIST1H4CP628052MINT-7899812 MINT-7900157
    HIST1H4DP628052MINT-7899812 MINT-7900157
    HIST1H4EP628052MINT-7899812 MINT-7900157
    HIST1H4FP628052MINT-7899812 MINT-7900157
    HIST1H4HP628052MINT-7899812 MINT-7900157
    HIST1H4IP628052MINT-7899812 MINT-7900157
    HIST1H4JP628052MINT-7899812 MINT-7900157
    HIST1H4KP628052MINT-7899812 MINT-7900157
    HIST1H4LP628052MINT-7899812 MINT-7900157
    HIST2H4AP628052MINT-7899812 MINT-7900157
    HIST2H4BP628052MINT-7899812 MINT-7900157
    HIST4H4P628052MINT-7899812 MINT-7900157
    HLTFQ145272MINT-7945693 MINT-7947479
    HNRNPFP525972MINT-7945693 MINT-7947479
    HNRNPH1P319432MINT-7945693 MINT-7947479
    HNRNPKP619782MINT-7945693 MINT-7947479
    HNRNPMP522722MINT-7945693 MINT-7947479
    HNRNPUQ008392MINT-7945693 MINT-7947479
    HSP90B1P146252MINT-7945693 MINT-7947479
    HSPA12AO433012MINT-7945693 MINT-7947479
    HSPA5P110212MINT-7945693 MINT-7947479
    HSPA8P111422MINT-7945693 MINT-7947479
    HSPD1P108092MINT-7945693 MINT-7947479
    ILF2Q129052MINT-7945693 MINT-7947479
    INTS1Q8N2012MINT-7945693 MINT-7947479
    INTS3Q68E012MINT-7945693 MINT-7947479
    IPO5O004102MINT-7945693 MINT-7947479
    IPO9Q96P702MINT-7945693 MINT-7947479
    IQGAP1P469402MINT-7945693 MINT-7947479
    KDM1AO603412MINT-7945693 MINT-7947479
    KHDRBS1Q076662MINT-7945693 MINT-7947479
    KIF11P527322MINT-7945693 MINT-7947479
    KIF21AQ7Z4S62MINT-7945693 MINT-7947479
    KIF2CQ996612MINT-7945693 MINT-7947479
    KIF4AO952392MINT-7945693 MINT-7947479
    KPNA2P522922MINT-7945693 MINT-7947479
    KPNB1Q149742MINT-7945693 MINT-7947479
    KRT17Q046952MINT-7899812 MINT-7900157
    KRT8P057872MINT-7899812 MINT-7900157
    LIMS1P480592MINT-7945693 MINT-7947479
    LRRC40Q9H9A62MINT-7945693 MINT-7947479
    LRWD1Q9UFC02MINT-7945693 MINT-7947479
    MAD1L1Q9Y6D92MINT-7945693 MINT-7947479
    MAP2K7O147332MINT-7945693 MINT-7947479
    MATR3P432432MINT-7945693 MINT-7947479
    MDN1Q9NU222MINT-7945693 MINT-7947479
    MED4Q9NPJ62MINT-7945693 MINT-7947479
    MRE11AP499592MINT-7945693 MINT-7947479
    MSH2P432462MINT-7945693 MINT-7947479
    MSH6P527012MINT-7945693 MINT-7947479
    MTA2O947762MINT-7945693 MINT-7947479
    MVPQ147642MINT-7945693 MINT-7947479
    MYH11P357492, ENSP000003796164MINT-7899812 STRING: ENSP00000379616
    MYH2Q9UKX22, ENSP000002455034MINT-7899812 STRING: ENSP00000245503
    MYL12AP191052, ENSP000002176524MINT-7899812 STRING: ENSP00000217652
    MYLK2Q9H1R32MINT-7899812 MINT-7900157
    MYO15BQ96JP22MINT-7945693 MINT-7947479
    NACC1Q96RE72MINT-7945693 MINT-7947479
    NBNO609342MINT-7945693 MINT-7947479
    NCAPD2Q150212MINT-7945693 MINT-7947479
    NCAPHQ150032MINT-7945693 MINT-7947479
    NCOR1O753762MINT-7945693 MINT-7947479
    NDC80O147772MINT-7945693 MINT-7947479
    NELFBQ8WX922MINT-7945693 MINT-7947479
    NIPBLQ6KC792MINT-7945693 MINT-7947479
    NONOQ152332MINT-7945693 MINT-7947479
    NPM1P067482MINT-7899812 MINT-7947479
    NSFP464592MINT-7945693 MINT-7947479
    NSUN5Q96P112MINT-7945693 MINT-7947479
    NUDCQ9Y2662MINT-7945693 MINT-7947479
    NUF2Q9BZD42MINT-7945693 MINT-7947479
    NUP155O756942MINT-7945693 MINT-7947479
    ORC2Q134162MINT-7945693 MINT-7947479
    ORC3Q9UBD52MINT-7945693 MINT-7947479
    OXSR1O957472MINT-7945693 MINT-7947479
    PAK4O960132MINT-7945693 MINT-7947479
    PARVAQ9NVD72MINT-7945693 MINT-7947479
    PARVBQ9HBI12MINT-7945693 MINT-7947479
    PCBP2Q153662MINT-7945693 MINT-7947479
    PDLIM7Q9NR122MINT-7945693 MINT-7947479
    PFKMP082372MINT-7945693 MINT-7947479
    PFKPQ018132MINT-7945693 MINT-7947479
    PHGDHO431752MINT-7945693 MINT-7947479
    PICALMQ134922MINT-7945693 MINT-7947479
    PKN2Q165132MINT-7945693 MINT-7947479
    PLECQ151492MINT-7945693 MINT-7947479
    PLRG1O436602MINT-7945693 MINT-7947479
    PNNQ9H3072MINT-7945693 MINT-7947479
    POLD1P283402MINT-7945693 MINT-7947479
    POLR1CO151602MINT-7945693 MINT-7947479
    PPP1CAP621362MINT-7945693 MINT-7947479
    PPP2R1AP301532MINT-7945693 MINT-7947479
    PRPF19Q9UMS42MINT-7945693 MINT-7947479
    PRPF6O949062MINT-7945693 MINT-7947479
    PRPF8Q6P2Q92MINT-7945693 MINT-7947479
    PSMC1P621912MINT-7945693 MINT-7947479
    PSMC2P359982MINT-7945693 MINT-7947479
    PSMC3P179802MINT-7945693 MINT-7947479
    PSMC4P436862MINT-7945693 MINT-7947479
    PSMC5P621952MINT-7945693 MINT-7947479
    PSMC6P623332MINT-7945693 MINT-7947479
    PSMD1Q994602MINT-7945693 MINT-7947479
    PSMD11O002312MINT-7945693 MINT-7947479
    PSMD12O002322MINT-7945693 MINT-7947479
    PSMD13Q9UNM62MINT-7945693 MINT-7947479
    PSMD2Q132002MINT-7945693 MINT-7947479
    PSMD3O432422MINT-7945693 MINT-7947479
    PTBP1P265992MINT-7945693 MINT-7947479
    RACGAP1Q9H0H52MINT-7945693 MINT-7947479
    RAD18Q9NS912MINT-7945693 MINT-7947479
    RAD50Q928782MINT-7945693 MINT-7947479
    RANBP2P497922MINT-7945693 MINT-7947479
    RANGAP1P460602MINT-7945693 MINT-7947479
    RBBP5Q152912MINT-7945693 MINT-7947479
    RBBP7Q165762MINT-7945693 MINT-7947479
    RBM17Q96I252MINT-7945693 MINT-7947479
    RBM39Q144982MINT-7945693 MINT-7947479
    RBM4Q9BWF32MINT-7945693 MINT-7947479
    RBM45Q8IUH32MINT-7945693 MINT-7947479
    RBMXP381592MINT-7945693 MINT-7947479
    RCOR1Q9UKL02MINT-7945693 MINT-7947479
    RFC2P352502MINT-7945693 MINT-7947479
    RFC3P409382MINT-7945693 MINT-7947479
    RFC4P352492MINT-7945693 MINT-7947479
    RFC5P409372MINT-7945693 MINT-7947479
    RIF1Q5UIP02MINT-7945693 MINT-7947479
    RPL13P263732MINT-7945693 MINT-7947479
    RPL22P352682MINT-7945693 MINT-7947479
    RPL31P628992MINT-7945693 MINT-7947479
    RPLP0P053882MINT-7945693 MINT-7947479
    RPS3P233962MINT-7945693 MINT-7899812
    RPS6KA4O756762MINT-7945693 MINT-7947479
    RPS6KB2Q9UBS02MINT-7945693 MINT-7947479
    RUVBL1Q9Y2652MINT-7945693 MINT-7947479
    SART1O432902MINT-7945693 MINT-7947479
    SCYL2Q6P3W72MINT-7945693 MINT-7947479
    SEH1LQ96EE32MINT-7945693 MINT-7947479
    SEPT9Q9UHD82MINT-7945693 MINT-7947479
    SETXQ7Z3332MINT-7945693 MINT-7947479
    SF3A1Q154592MINT-7945693 MINT-7947479
    SF3A3Q128742MINT-7945693 MINT-7947479
    SF3B1O755332MINT-7945693 MINT-7947479
    SF3B14Q9Y3B42MINT-7945693 MINT-7947479
    SF3B2Q134352MINT-7945693 MINT-7947479
    SF3B3Q153932MINT-7945693 MINT-7947479
    SFPQP232462MINT-7945693 MINT-7947479
    SHROOM3Q8TF722MINT-7945693 MINT-7947479
    SMARCA5O602642MINT-7945693 MINT-7947479
    SMARCAD1Q9H4L72MINT-7945693 MINT-7947479
    SMARCB1Q128242MINT-7945693 MINT-7947479
    SMARCC1Q929222MINT-7945693 MINT-7947479
    SMARCC2Q8TAQ22MINT-7945693 MINT-7947479
    SMARCD1Q96GM52MINT-7945693 MINT-7947479
    SMARCE1Q969G32MINT-7945693 MINT-7947479
    SMC1AQ146832MINT-7945693 MINT-7947479
    SMC2O953472MINT-7945693 MINT-7947479
    SMC3Q9UQE72MINT-7945693 MINT-7947479
    SMC4Q9NTJ32MINT-7945693 MINT-7947479
    SMCHD1A6NHR92MINT-7945693 MINT-7947479
    SMN1Q166372MINT-7945693 MINT-7947479
    SMN2Q166372MINT-7945693 MINT-7947479
    SNRNP200O756432MINT-7945693 MINT-7947479
    SNRNP40Q96DI72MINT-7945693 MINT-7947479
    SNRNP70P086212MINT-7945693 MINT-7947479
    SNRPD3P623182MINT-7945693 MINT-7947479
    SPATA5Q8NB902MINT-7945693 MINT-7947479
    SPTBN1Q010822MINT-7945693 MINT-7947479
    SRP54P610112MINT-7945693 MINT-7947479
    SRP68Q9UHB92MINT-7945693 MINT-7947479
    SRP72O760942MINT-7945693 MINT-7947479
    SRRM1Q8IYB32MINT-7945693 MINT-7947479
    SRSF1Q079552MINT-7945693 MINT-7947479
    SRSF7Q166292MINT-7945693 MINT-7947479
    SUGT1Q9Y2Z02MINT-7945693 MINT-7947479
    SYMPKQ927972MINT-7945693 MINT-7947479
    TARDBPQ131482MINT-7945693 MINT-7947479
    TBL1XR1Q9BZK72MINT-7945693 MINT-7947479
    TCP1P179872MINT-7945693 MINT-7947479
    THRAP3Q9Y2W12MINT-7945693 MINT-7947479
    TIAL1Q010852MINT-7945693 MINT-7947479
    TLN1Q9Y4902MINT-7945693 MINT-7947479
    TMPOP421662MINT-7945693 MINT-7947479
    TRAP1Q129312MINT-7945693 MINT-7947479
    TRIM28Q132632MINT-7945693 MINT-7947479
    TRIP13Q156452MINT-7945693 MINT-7947479
    TRUB1Q8WWH52MINT-7945693 MINT-7947479
    TSG101Q998162MINT-7945693 MINT-7947479
    TUBA1CQ9BQE32MINT-7900157 MINT-7947479
    TUBA4AP683662MINT-7945693 MINT-7947479
    TUBBP074372MINT-7945693 MINT-7947479
    TUBB4BP683712MINT-7945693 MINT-7947479
    TUBG1P232582MINT-7945693 MINT-7947479
    TUBGCP2Q9BSJ22MINT-7945693 MINT-7947479
    TUBGCP3Q96CW52MINT-7945693 MINT-7947479
    TWF1Q127922MINT-7945693 MINT-7947479
    U2AF1Q010812MINT-7945693 MINT-7947479
    U2AF2P263682MINT-7945693 MINT-7947479
    U2SURPO150422MINT-7945693 MINT-7947479
    UBA5Q9GZZ92MINT-7945693 MINT-7947479
    UBE2MP610812MINT-7945693 MINT-7947479
    UBE2NP610882MINT-7945693 MINT-7947479
    UBL4AP114412MINT-7945693 MINT-7947479
    UCHL5Q9Y5K52MINT-7945693 MINT-7947479
    UNC45AQ9H3U12MINT-7945693 MINT-7947479
    UPF1Q929002MINT-7945693 MINT-7947479
    UPF2Q9HAU52MINT-7945693 MINT-7947479
    USP39Q53GS92MINT-7945693 MINT-7947479
    VASPP505522MINT-7945693 MINT-7899812
    VPS33BQ9H2672MINT-7945693 MINT-7947479
    WDR18Q9BV382MINT-7945693 MINT-7947479
    WDR33Q9C0J82MINT-7945693 MINT-7947479
    XRN2Q9H0D62MINT-7945693 MINT-7947479
    ZNF638Q149662MINT-7945693 MINT-7947479
    MYO5BQ9ULV03I2D: score=4 
    NAA10P412273I2D: score=4 
    AGLP355733I2D: score=3 
    EMDP504023I2D: score=2 
    IQGAP2Q135763I2D: score=2 
    MCM5P339923I2D: score=2 
    MMEP084733I2D: score=2 
    ANAPC10Q9UM133I2D: score=1 
    ARRB1P494073I2D: score=1 
    ARRB2P321213I2D: score=1 
    ATG13O751433I2D: score=1 
    ATG5Q9H1Y03I2D: score=1 
    BECN1Q144573I2D: score=1 
    C12orf44Q9BSB43I2D: score=1 
    CAMKK2Q96RR43I2D: score=1 
    CDC14AQ9UNH53I2D: score=1 
    CLN3Q132863I2D: score=1 
    CLUHO751533I2D: score=1 
    CNDP2Q96KP43I2D: score=1 
    CPOXP365513I2D: score=1 
    CSF1P096033I2D: score=1 
    CUX1Q139483I2D: score=1 
    DDA1Q9BW613I2D: score=1 
    DDIT3P356383I2D: score=1 
    EIF2AK4Q9P2K83I2D: score=1 
    ENO3P139293I2D: score=1 
    FZR1Q9UM113I2D: score=1 
    GABARAPL1Q9H0R83I2D: score=1 
    GBASO753233I2D: score=1 
    GNB2L1P632443I2D: score=1 
    GRIN2BQ132243I2D: score=1 
    HSPH1Q925983I2D: score=1 
    KIAA0020Q153973I2D: score=1 
    KIAA0368Q5VYK33I2D: score=1 
    MOB1AQ9H8S93I2D: score=1 
    NAA16Q6N0693I2D: score=1 
    NOL6Q9H6R43I2D: score=1 
    NRBF2Q96F243I2D: score=1 
    PKNOX1P553473I2D: score=1 
    PLEKHA5Q9HAU03I2D: score=1 
    PPIFP304053I2D: score=1 
    PRKAG2Q9UGJ03I2D: score=1 
    PXNP490233I2D: score=1 
    RPL30P628883I2D: score=1 
    RPS20P608663I2D: score=1 
    RPS24P628473I2D: score=1 
    RPS27AP629793I2D: score=1 
    SH3GLB2Q9NR463I2D: score=1 
    SHBQ154643I2D: score=1 
    SQLEQ145343I2D: score=1 
    TADA2AO754783I2D: score=1 
    TAF6P498483I2D: score=1 
    TBPP202263I2D: score=1 
    TECPR1Q7Z6L13I2D: score=1 
    TSGA10Q9BZW73I2D: score=1 
    UBE2D4Q9Y2X83I2D: score=1 
    UBE2KP610863I2D: score=1 
    VBP1P617583I2D: score=1 
    VCLP182063I2D: score=1 
    ACIN1Q9UKV32MINT-7945693
    ACTN2P356092MINT-7899812
    ACTN3Q080432MINT-7899812
    AKAP8O438232MINT-7947479
    ANAPC2Q9UJX62MINT-7947479
    ANAPC7Q9UJX32MINT-7947479
    ANXA11P509952MINT-7947479
    AP3B1O002032MINT-7945693
    APBB1IPQ7Z5R62MINT-7945693
    API5Q9BZZ52MINT-7945693
    AQRO603062MINT-7945693
    ARAP1Q96P482MINT-7945693
    ARF4P180852MINT-7945693
    ARF5P840852MINT-7945693
    ARFGEF2Q9Y6D52MINT-7945693
    ARGLU1Q9NWB62MINT-7947479
    ASUNQ9NVM92MINT-7945693
    ATMQ133152MINT-7945693
    ATP5BP065762MINT-7900157
    ATRQ135352MINT-7945693
    ATRXP461002MINT-7945693
    AURKAO149652MINT-7945693
    BABAM1Q9NWV82MINT-7945693
    BANK1Q8NDB22MINT-7899812
    BCL7CQ8WUZ02MINT-7945693
    BIDP559572MINT-7947479
    BLMP541322MINT-7945693
    BRD2P254402MINT-7947479
    BRD4O608852MINT-7947479
    BRD7Q9NPI12MINT-7947479
    BRIX1Q8TDN62MINT-7945693
    BZW2Q9Y6E22MINT-7945693
    C7orf13Q8NI282MINT-7947479
    C7orf55-LUC7L2Q9Y3832MINT-7945693
    CACNA1SQ136982MINT-7899812
    CAND1Q86VP62MINT-7945693
    CARD10Q9BWT72MINT-7947479
    CASC5Q8NG312MINT-7947479
    CCNT1O605632MINT-7945693
    CDC20Q128342MINT-7947479
    CDK1P064932MINT-7945693
    CDK12Q9NYV42MINT-7945693
    CDK3Q005262MINT-7945693
    CEP250Q9BV732MINT-7899812
    CHD3Q128732MINT-7945693
    CHD4Q148392MINT-7945693
    CHD7Q9P2D12MINT-7945693
    CLASP1Q7Z4602MINT-7947479
    CLINT1Q146772MINT-7947479
    CLP1Q929892MINT-7945693
    CNOT10Q9H9A52MINT-7947479
    CNOT3O751752MINT-7947479
    COPS3Q9UNS22MINT-7945693
    COPS6Q7L5N12MINT-7945693
    CPNE3O751312MINT-7945693
    CPS1P313272MINT-7900157
    CPSF1Q105702MINT-7945693
    CPSF4O956392MINT-7945693
    CSDAP169892MINT-7945693
    CSKP412402MINT-7945693
    CTNND1O607162MINT-7947479
    CTTNQ142472MINT-7945693
    CWC15Q9P0132MINT-7947479
    DCTN1Q142032MINT-7945693
    DDB1Q165312MINT-7947479
    DDX1Q924992MINT-7945693
    DDX21Q9NR302MINT-7945693
    DDX23Q9BUQ82MINT-7945693
    DDX46Q7L0142MINT-7945693
    DDX47Q9H0S42MINT-7947479
    DDX6P261962MINT-7947479
    DESP176612MINT-7899812
    DHX8Q145622MINT-7945693
    DHX9Q082112MINT-7945693
    DIAPH3Q9NSV42MINT-7945693
    DNAJC13O751652MINT-7945693
    DOCK1Q141852MINT-7945693
    DOCK2Q926082MINT-7945693
    DOCK5Q9H7D02MINT-7947479
    DOCK8Q8NF502MINT-7947479
    DPF2Q927852MINT-7945693
    DTYMKP239192MINT-7947479
    DYNC1LI1Q9Y6G92MINT-7947479
    EBNA1BP2Q998482MINT-7945693
    ECT2Q9H8V32MINT-7947479
    EDC4Q6P2E92MINT-7947479
    EEFSECP577722MINT-7945693
    EHMT1Q9H9B12MINT-7947479
    EIF2B4Q9UI102MINT-7947479
    EIF2DP412142MINT-7947479
    EIF2S1P051982MINT-7945693
    EIF3BP558842MINT-7947479
    EIF3EP602282MINT-7945693
    EIF3HO153722MINT-7945693
    EIF3LQ9Y2622MINT-7945693
    EIF4A2Q142402MINT-7947479
    ELF2Q157232MINT-7947479
    ENSG00000258947Q135092MINT-7945693
    EPB41L3Q9Y2J22MINT-7947479
    ERAL1O756162MINT-7947479
    ERCC1P079922MINT-7947479
    ERCC6LQ2NKX82MINT-7947479
    EWSR1Q018442MINT-7947479
    EXOC1Q9NV702MINT-7945693
    EXOC3O606452MINT-7945693
    EXOSC6Q5RKV62MINT-7945693
    FAF1Q9UNN52MINT-7947479
    FAM105BQ96BN82MINT-7945693
    FANCD2Q9BXW92MINT-7947479
    FIP1L1Q6UN152MINT-7945693
    FUBP1Q96AE42MINT-7945693
    FYTTD1Q96QD92MINT-7945693
    G3BP2Q9UN862MINT-7945693
    GAPDHP044062MINT-7947479
    GATAD2BQ8WXI92MINT-7945693
    GEMIN6Q8WXD52MINT-7947479
    GMPSP499152MINT-7947479
    GNA14O958372MINT-7945693
    GNASP630922MINT-7947479
    GNB3P165202MINT-7947479
    GOLGB1Q147892MINT-7947479
    GPS2Q132272MINT-7947479
    GSPT1P151702MINT-7945693
    GTF3C1Q127892MINT-7945693
    GTF3C3Q9Y5Q92MINT-7945693
    GTF3C4Q9UKN82MINT-7945693
    GTF3C5Q9Y5Q82MINT-7947479
    GTPBP1O001782MINT-7947479
    GTPBP4Q9BZE42MINT-7945693
    H2AFXP161042MINT-7899812
    HAUS7Q998712MINT-7947479
    HIC2Q96JB32MINT-7947479
    HIST1H1CP164032MINT-7899812
    HIST1H1DP164022MINT-7899812
    HIST1H1TP224922MINT-7899812
    HIST1H2AGP0C0S82MINT-7899812
    HIST1H2AIP0C0S82MINT-7899812
    HIST1H2AKP0C0S82MINT-7899812
    HIST1H2ALP0C0S82MINT-7899812
    HIST1H2AMP0C0S82MINT-7899812
    HMGCS2P548682MINT-7900157
    HNRNPA0Q131512MINT-7945693
    HNRNPA1P096512MINT-7945693
    HNRNPA3P519912MINT-7945693
    HNRNPABQ997292MINT-7945693
    HNRNPDQ141032MINT-7945693
    HNRNPRO433902MINT-7945693
    HSPA6P170662MINT-7947479
    HTATSF1O437192MINT-7945693
    HUWE1Q7Z6Z72MINT-7947479
    IKQ131232MINT-7945693
    IKBKAPO951632MINT-7947479
    ILF3Q129062MINT-7945693
    ILKQ134182MINT-7945693
    INTS12Q96CB82MINT-7945693
    INTS6Q9UL032MINT-7947479
    INTS8Q75QN22MINT-7947479
    IPO7O953732MINT-7947479
    ITPK1Q135722MINT-7947479
    KANSL1Q7Z3B32MINT-7947479
    KIAA1279Q96EK52MINT-7945693
    KIF27Q86VH22MINT-7945693
    KPNA1P522942MINT-7945693
    KRT18P057832MINT-7899812
    KTI12Q96EK92MINT-7945693
    LAS1LQ9Y4W22MINT-7947479
    LDLRAP1Q5SW962MINT-7945693
    LENG9Q96B702MINT-7947479
    LMO7Q8WWI12MINT-7947479
    LRRC1Q9BTT62MINT-7947479
    LRRC47Q8N1G42MINT-7945693
    LUC7L2Q9Y3832MINT-7945693
    MAGED2Q9UNF12MINT-7945693
    MAGEE2Q8TD902MINT-7947479
    MAP2K2P365072MINT-7945693
    MAP2K3P467342MINT-7945693
    MAP2K4P459852MINT-7947479
    MAP7Q142442MINT-7947479
    MARK2Q7KZI72MINT-7947479
    MBD3O959832MINT-7945693
    MED12Q930742MINT-7947479
    MED12LQ86YW92MINT-7947479
    MED16Q9Y2X02MINT-7947479
    MELKQ146802MINT-7947479
    METTL13Q8N6R02MINT-7945693
    MLH1P406922MINT-7945693
    MLKLQ8NB162MINT-7945693
    MLL2O146862MINT-7945693
    MORF4L1Q9UBU82MINT-7945693
    MORF4L2Q150142MINT-7945693
    MPP2Q141682MINT-7947479
    MTA3Q9BTC82MINT-7947479
    MYBBP1AQ9BQG02MINT-7947479
    MYH3P110552MINT-7899812
    NAT10Q9H0A02MINT-7947479
    NCAPGQ9BPX32MINT-7945693
    NCOR2Q9Y6182MINT-7945693
    NELFCDQ8IXH72MINT-7945693
    NF1P213592MINT-7947479
    NFICP086512MINT-7945693
    NFKB2Q006532MINT-48615
    NOLC1Q149782MINT-7945693
    NR2C2P491162MINT-7945693
    NR2F2P244682MINT-7945693
    NR2F6P105882MINT-7945693
    NRG1Q022972MINT-7947479
    NUDT21O438092MINT-7947479
    NUP107P577402MINT-7947479
    NUP153P497902MINT-7945693
    NUP37Q8NFH42MINT-7945693
    NUP93Q8N1F72MINT-7947479
    OLA1Q9NTK52MINT-7945693
    PABPC1P119402MINT-7945693
    PABPN1Q86U422MINT-7945693
    PAK1Q131532MINT-7945693
    PARP1P098742MINT-7947479
    PARP4Q9UKK32MINT-7945693
    PAXIP1Q6ZW492MINT-7945693
    PBRM1Q86U862MINT-7945693
    PCBP1Q153652MINT-7947479
    PCF11O949132MINT-7945693
    PCNTO956132MINT-7947479
    PDCD6IPQ8WUM42MINT-7945693
    PELOQ9BRX22MINT-7947479
    PELP1Q8IZL82MINT-7945693
    PIK3R4Q995702MINT-7945693
    PKP3Q9Y4462MINT-7945693
    POGZQ7Z3K32MINT-7945693
    POLEQ078642MINT-7945693
    POLR2AP249282MINT-7945693
    POLR2EP193882MINT-7945693
    POLR3DP054232MINT-7947479
    POLR3EQ9NVU02MINT-7947479
    PPFIA1Q131362MINT-7947479
    PPM1DO152972MINT-7947479
    PPP2R1BP301542MINT-7945693
    PRCCQ927332MINT-7947479
    PRPF3O433952MINT-7947479
    PRPF40AO754002MINT-7945693
    PRPF4BQ135232MINT-7947479
    PSTPIP2Q9H9392MINT-7947479
    PTBP2Q9UKA92MINT-7947479
    PTBP3O957582MINT-7947479
    PUF60Q9UHX12MINT-7945693
    PUM1Q146712MINT-7947479
    PUM2Q8TB722MINT-7945693
    PURAQ005772MINT-7945693
    RAD21O602162MINT-7945693
    RAE1P784062MINT-7945693
    RAVER1Q8IY672MINT-7947479
    RBBP4Q090282MINT-7947479
    RBM10P981752MINT-7945693
    RBM14Q96PK62MINT-7945693
    RBM15Q96T372MINT-7945693
    RBM7Q9Y5802MINT-7947479
    RFX1P226702MINT-7947479
    RFX5P483822MINT-7947479
    RING1Q065872MINT-7945693
    RIOK1Q9BRS22MINT-7945693
    RNF130Q86XS82MINT-7947479
    RNF17Q9BXT82MINT-7947479
    RNF2Q994962MINT-7945693
    RPL12P300502MINT-7945693
    RPL19P840982MINT-7945693
    RPL23AP627502MINT-7945693
    RPL24P837312MINT-7947479
    RPL3P390232MINT-7945693
    RPL36Q9Y3U82MINT-7945693
    RPL4P365782MINT-7945693
    RPL7AP624242MINT-7945693
    RPL8P629172MINT-7945693
    RPS13P622772MINT-7947479
    RPS14P622632MINT-7945693
    RPS18P622692MINT-7945693
    RPS19P390192MINT-7945693
    RPS25P628512MINT-7945693
    RXRBP287022MINT-7947479
    SCAF8Q9UPN62MINT-7947479
    SCRIBQ141602MINT-7947479
    SEC23AQ154362MINT-7947479
    SEC23BQ154372MINT-7945693
    SEC24CP539922MINT-7947479
    SEC31BQ9NQW12MINT-7945693
    SENP3Q9H4L42MINT-7947479
    SF3A2Q154282MINT-7947479
    SF3B4Q154272MINT-7945693
    SFNP319472MINT-7900157
    SHC1P293532MINT-7947479
    SHOC2Q9UQ132MINT-7945693
    SIN3AQ96ST32MINT-7947479
    SKIV2L2P422852MINT-7947479
    SMARCA2P515312MINT-7945693
    SNAPC4Q5SXM22MINT-7947479
    SND1Q7KZF42MINT-7945693
    SNRPAP090122MINT-7947479
    SNRPA1P096612MINT-7947479
    SNRPB2P085792MINT-7945693
    SNRPD1P623142MINT-7947479
    SNRPEP623042MINT-7947479
    SNUPNO951492MINT-7945693
    SNX12Q9UMY42MINT-7947479
    SNX2O607492MINT-7947479
    SOGA2Q9Y4B52MINT-7947479
    SPATA5L1Q9BVQ72MINT-7945693
    SPENQ96T582MINT-7947479
    SQSTM1Q135012MINT-7945693
    SREK1Q8WXA92MINT-7947479
    SRP19P091322MINT-7945693
    SRRM2Q9UQ352MINT-7945693
    SRSF11Q055192MINT-7945693
    SRSF2Q011302MINT-7945693
    SRSF3P841032MINT-7945693
    SRSF4Q081702MINT-7947479
    SRSF5Q132432MINT-7945693
    SRSF6Q132472MINT-7945693
    SSUH2Q9Y2M22MINT-7947479
    STAB1Q9NY152MINT-7947479
    STAG1Q8WVM72MINT-7945693
    STAG2Q8N3U42MINT-7947479
    STAT3P407632MINT-7947479
    STK24Q9Y6E02MINT-7947479
    SUPT16HQ9Y5B92MINT-7947479
    SUPV3L1Q8IYB82MINT-7945693
    SYNCRIPO605062MINT-7945693
    TAF12Q165142MINT-7945693
    TAF15Q928042MINT-7947479
    TAF5LO755292MINT-7947479
    TAF9Q165942MINT-7945693
    TANC2Q9HCD62MINT-7947479
    TAOK1Q7L7X32MINT-7945693
    TGIF2LYQ8IUE02MINT-7899812
    THAP1Q9NVV92MINT-7947479
    THOC1Q96FV92MINT-7945693
    THOC2Q8NI272MINT-7945693
    TLN2Q9Y4G62MINT-7947479
    TMOD3Q9NYL92MINT-7947479
    TNFAIP2Q031692MINT-7947479
    TNKS1BP1Q9C0C22MINT-7947479
    TNPO1Q929732MINT-7947479
    TOX4O948422MINT-7945693
    TPM1P094932MINT-7899812
    TPRP122702MINT-7947479
    TPX2Q9ULW02MINT-7947479
    TRIM21P194742MINT-7947479
    TRIP12Q146692MINT-7945693
    TRMT1LQ7Z2T52MINT-7947479
    TRRAPQ9Y4A52MINT-7947479
    TSC2P498152MINT-7899812
    TTKP339812MINT-7945693
    TUBA3EQ6PEY22MINT-7945693
    TUBB1Q9H4B72MINT-7945693
    TUBB2AQ138852MINT-7899812
    TUBB3Q135092MINT-7945693
    TUBGCP4Q9UGJ12MINT-7947479
    TUT1Q9H6E52MINT-7900157
    UBE2Q1Q7Z7E82MINT-7945693
    UBE2SQ167632MINT-7947479
    UBN1Q9NPG32MINT-7947479
    UMPSP111722MINT-7947479
    USO1O607632MINT-7947479
    USP10Q146942MINT-7947479
    USP24Q9UPU52MINT-7947479
    USP42Q9H9J42MINT-7899812
    USP48Q86UV52MINT-7945693
    VPS33AQ96AX12MINT-7947479
    VPS36Q86VN12MINT-7947479
    VPS51Q9UID32MINT-7947479
    VRK1Q999862MINT-7945693
    WAPALQ7Z5K22MINT-7945693
    WDR5P619642MINT-7945693
    WIZO957852MINT-7945693
    WNK4Q96J922MINT-7900157
    WRNIP1Q96S552MINT-7947479
    XPO5Q9HAV42MINT-7947479
    XPO6Q96QU82MINT-7945693
    XRCC6P129562MINT-7945693
    YEATS4O956192MINT-7947479
    YLPM1P497502MINT-7947479
    YTHDC2Q9H6S02MINT-7945693
    YWHAHQ049172MINT-7899812
    YY1P254902MINT-7945693
    ZBTB7CA1YPR02MINT-7947479
    ZC3HC1Q86WB02MINT-7947479
    ZNF326Q5BKZ12MINT-7945693
    MYL6ENSP000002934224STRING: ENSP00000293422
    RHOBENSP000002722334STRING: ENSP00000272233
    CGNENSP000002716364STRING: ENSP00000271636
    MYL10ENSP000002231674STRING: ENSP00000223167
    MYL12BENSP000002375004STRING: ENSP00000237500
    MYL2ENSP000002288414STRING: ENSP00000228841
    MYL5ENSP000003830234STRING: ENSP00000383023
    MYL7ENSP000002233644STRING: ENSP00000223364
    MYLPFENSP000003252394STRING: ENSP00000325239
    URI1ENSP000003760974STRING: ENSP00000376097
    UBCENSP000003448184STRING: ENSP00000344818
    FBXO25ENSP000002763264STRING: ENSP00000276326
    IQCB1ENSP000003115054STRING: ENSP00000311505
    MYH1ENSP000002262074STRING: ENSP00000226207
    MYH4ENSP000002553814STRING: ENSP00000255381
    MYH6ENSP000003486344STRING: ENSP00000348634
    MYL1ENSP000003072804STRING: ENSP00000307280
    MYL4ENSP000003470554STRING: ENSP00000347055
    MYL6BENSP000002074374STRING: ENSP00000207437
    SHROOM1ENSP000003242454STRING: ENSP00000324245
    SHROOM4ENSP000002892924STRING: ENSP00000289292
    TRIM32ENSP000003630954STRING: ENSP00000363095
    CYTIPENSP000002641924STRING: ENSP00000264192
    SUMO2ENSP000004059654STRING: ENSP00000405965
    KNCNENSP000003796074STRING: ENSP00000379607
    SIRT7ENSP000003294664STRING: ENSP00000329466
    About this table

    Gene Ontology (GO): 5/26 biological process terms (GO ID links to tree view) (see all 26):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000212meiotic spindle organization IEA--
    GO:0000904cell morphogenesis involved in differentiation ----
    GO:0000910cytokinesis IMP15774463
    GO:0001525angiogenesis IDA16403913
    GO:0001701in utero embryonic development IEA--


    MYH9 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MYH9 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MYH9 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for MYH9 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    (R)-(+)-BlebbistatinSelective inhibitor of myosin II. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760)--
    (S)-(-)-BlebbistatinSelective inhibitor of myosin II. Active enantiomer of (±)-blebbistatin (Cat. No. 1760)[856925-71-8]
    (±)-BlebbistatinSelective inhibitor of myosin II[674289-55-5]
    4 Novoseek chemical compound relationships for MYH9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phorbol 21.5 1 15496418 (1)
    calcium 0 1 18312684 (1)
    threonine 0 1 10945986 (1)
    tyrosine 0 1 19401332 (1)

    Search CenterWatch for drugs/clinical trials and news about MYH9 

    Transcripts
    for MYH9 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MYH9 gene: 
    NM_002473.4  

    Unigene Cluster for MYH9:

    Myosin, heavy chain 9, non-muscle
    Hs.474751  [show with all ESTs]
    Unigene Representative Sequence: NM_002473
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000216181(uc003apg.3 uc003aph.1) ENST00000475726 ENST00000486218
    ENST00000459960 ENST00000495928 ENST00000473022 ENST00000477189 ENST00000472210
    ENST00000463027 ENST00000463293 ENST00000401701(uc003api.1) ENST00000456729


    miRNA
    Products:             		 OriGene 3'-UTR Clone: MYH9
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYH9
    8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate MYH9 (see all 47):
    hsa-miR-194* hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-300 hsa-miR-376b hsa-miR-25 hsa-miR-449a hsa-miR-10b*
    SwitchGear 3'UTR luciferase reporter plasmid: MYH9 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYH9 (see all 7)
    OriGene shRNA RFP: MYH9
    OriGene siRNA: MYH9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYH9
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYH9 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYH9
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MYH9 (NM_002473)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYH9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYH9 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYH9
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYH9
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYH9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYH9

    Additional cDNA sequence: 

    AB191263.1 AB290175.1 AK025219.1 AK025393.1 AK131080.1 AK291609.1 AK304840.1 BC011915.2 
    BC049849.1 BC090921.1 BC111387.1 BC113067.1 BC131741.1 CR456526.1 D11393.1 HQ326701.1 
    L29141.1 M31013.1 M69180.1 M81105.1 

    24/58 DOTS entries (see all 58):

    DT.95126859  DT.119239  DT.92464957  DT.95347813  DT.97761844  DT.100659644  DT.100659636  DT.100659653 
    DT.91985714  DT.120655569  DT.95347783  DT.120655540  DT.100659655  DT.120655825  DT.120655658  DT.100659642 
    DT.120655748  DT.100659641  DT.120655676  DT.91811745  DT.102840742  DT.95347683  DT.97867641  DT.120655554 

    24/1191 AceView cDNA sequences (see all 1191):

    BQ433063 AI287313 BQ058956 H55296 BU622803 BU169188 BE311756 BU626369 
    CA388984 AA856897 BF689443 BE795516 AW008451 CF995724 CK000662 AA666146 
    BU500273 AI925868 BU501267 BU632240 BQ947257 AI859664 BQ876769 BI020066 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MYH9 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b ^ 20 ^ 21 ^
    SP1:                                                  -                             -                                                                           
    SP2:              -                                   -                             -                                                                           
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27 ^ 28a · 28b ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35a · 35b ^ 36a · 36b ^ 37a · 37b ^ 38a · 38b · 38c ^ 39 ^
    SP1:                          -     -     -     -     -     -     -     -     -     -     -     -     -                                                         
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                  -     -   
    SP5:                                                                                                                                                            

    ExUns: 40a · 40b · 40c ^ 41a · 41b ^ 42a · 42b ^ 43 ^ 44a · 44b ^ 45a · 45b · 45c ^ 46a · 46b
    SP1:  -                                                                                       
    SP2:                                                                                          
    SP3:                                                                                          
    SP4:  -     -     -     -                                                                     
    SP5:  -           -     -     -     -                                                         


    ECgene alternative splicing isoforms for MYH9

    Expression
    for MYH9 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MYH9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGCTAAAAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MYH9 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Skeletal MuscleHyoid Arch MusclesMyoblastsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMyoblastsSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MYH9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MYH9

    SOURCE GeneReport for Unigene cluster: Hs.474751

    UniProtKB/Swiss-Prot: MYH9_HUMAN, P35579
    Tissue specificity: In the kidney, expressed in the glomeruli. Also expressed in leukocytes

        SABiosciences Expression via Pathway-Focused PCR Arrays including MYH9: 
              Cell Surface Markers in human mouse rat
              Cell Motility in human mouse rat

    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYH9
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYH9
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYH9
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYH9
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYH9

    Orthologs
    for MYH9 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for MYH9 gene from 6/22 species (see all 22)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MYH91 myosin, heavy chain 9, non-muscle 80.91(n)
    92.75(a)    		   396469  NM_205477.1  NP_990808.1 
    lizard
    (Anolis carolinensis)    		 Reptilia MYH96
    		 --
    		 92(a)
    		 1 ↔ 1
    		 5(22051567-22103593)
    African clawed frog
    (Xenopus laevis)    		 Amphibia AF055895.12   -- 76.39(n)    AF055895.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BC045324.12   -- 77.88(n)   393797  BC045324.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta zip3 NOT muscle attachment myosin ATPase 61(a)     --
    worm
    (Caenorhabditis elegans)    		 Secernentea nmy-13 myosin 50(a)
    (best of 6)    		   X(2944856-2952845)   --


    ENSEMBL Gene Tree for MYH9 (if available)
    TreeFam Gene Tree for MYH9 (if available) 

    Paralogs
    for MYH9 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MYH9 gene
    MYH82  MYH12  MYH22  MYH112  MYH142  MYH132  MYH102  MYH7B2  
    MYH42  MYH32  MYH152  MYH62  MYH72  
    18/39 SIMAP similar genes for MYH9 using alignment to 6 protein entries:     MYH9_HUMAN (see all proteins) (see all similar genes):
    FLJ00279    DKFZp686D10126    MYH11    MYH10    MYH14    MYO1C
    MYO1E    MYO3B    MYO9B variant protein    MYH7    MYO15A    MYO9A
    MYH6    MYO1H    MYH13    MYH2    MYO1G    MYH7B

    MYH9 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MYH9
    PGOHUM00000263186


    Genomic Variants
    for MYH9 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2156 NCBI SNPs in MYH9 are shown (see all 2156)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 22 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs169966521,2
    		Cnon-pathogenic36696249(+) TGGTCA/TCCTTC 2 E V mis1 spl34Minor allele frequency- T:0.01NA 144
    rs803388351,2
    		Cpathogenic36678800(-) CCCGCC/TGAATG 2 R * stg10--------
    rs803388341,2
    		Cpathogenic36680520(-) GGACCA/GAGAAG 2 K E mis10--------
    rs803388311,2
    		Cpathogenic36688106(-) TGGACA/C/G/T 
                ACCTG     		4 N H D Y mis10--------
    rs803388291,2
    		Cpathogenic36691115(-) CAAAAC/TGTGAG 2 R C mis10--------
    rs803388281,2
    		Cpathogenic36702021(-) CTGCCA/GCCAGG 2 H R mis10--------
    rs803388271,2
    		Cpathogenic36702030(-) CATCCA/GTATCT 2 H R mis10--------
    rs803388261,2
    		Cpathogenic36702031(-) GCATCC/TGTATC 2 R C mis10--------
    rs1419046821,2
    		C,other36689833(+) CCAGCA/GCGGAG 2 A V mis10--------
    rs1921918811,2
    		--36676888(+) CAATCG/TTAGCT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for MYH9 (36677323 - 36784063 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for MYH9
         1 CNV: 5183
    Human Gene Mutation Database (HGMD): MYH9

    Locus Specific Mutation Databases (LSDB): MYH9

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYH9
    DNA2.0 Custom Variant and Variant Library Synthesis for MYH9

    Disorders / Diseases
    for MYH9 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MYH9 for disorders           About GeneDecksing

    OMIM gene information: 160775   
    OMIM disorders: 155100  153640  605249  603622  153650  600208  
    UniProtKB/Swiss-Prot: MYH9_HUMAN, P35579
  • Defects in MYH9 are the cause of May-Hegglin anomaly (MHA) [MIM:155100]. MHA is an autosomal dominant
    • macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukokyte inclusions appearing as highly
    parallel paracrystalline bodies
  • Defects in MYH9 are the cause of Sebastian syndrome (SBS) [MIM:605249]. SBS is an autosomal dominant
    • macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukocyte inclusions that are smaller and
    less organized than in May-Hegglin anomaly
  • Defects in MYH9 are the cause of Fechtner syndrome (FTNS) [MIM:153640]. FTNS is an autosomal dominant
    • macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukocyte inclusions that are small and
    poorly organized. Additionally, FTNS is distinguished by Alport-like clinical features of sensorineural deafness,
    cataracts and nephritis
  • Defects in MYH9 are the cause of Alport syndrome with macrothrombocytopenia (APSM) [MIM:153650]. APSM is an
    • autosomal dominant disorder characterized by the association of ocular lesions, sensorineural hearing loss and
    nephritis (Alport syndrome) with platelet defects
  • Defects in MYH9 are the cause of Epstein syndrome (EPS) [MIM:153650]. EPS is an autosomal dominant disorder
    • characterized by the association of macrothrombocytopathy, sensorineural hearing loss and nephritis
  • Defects in MYH9 are the cause of deafness autosomal dominant type 17 (DFNA17) [MIM:603622]. DFNA17 is a form
    • of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear,
    the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA17 is characterized by
    progressive hearing impairment and cochleosaccular degeneration
  • Defects in MYH9 are the cause of macrothrombocytopenia with progressive sensorineural deafness (MPSD)
    • [MIM:600208]. MPSD is an autosomal dominant disorder characterized by the association of macrothrombocytopathy and
    progressive sensorineural hearing loss without renal dysfunction
  • Note=Subjects with mutations in the motor domain of MYH9 present with severe thrombocytopenia and develop
    • nephritis and deafness before the age of 40 years, while those with mutations in the tail domain have a much lower
    risk of noncongenital complications and significantly higher platelet counts. The clinical course of patients with
    mutations in the four most frequently affected residues of MYH9 (responsible for 70% of MYH9-related cases) were
    evaluated. Mutations at residue 1933 do not induce kidney damage or cataracts and cause deafness only in the elderly,
    those in position 702 result in severe thrombocytopenia and produce nephritis and deafness at a juvenile age, while
    alterations at residue 1424 or 1841 result in intermediate clinical pictures
  • Note=Genetic variations in MYH9 are associated with non-diabetic end stage renal disease (ESRD)

    • 20/60 diseases for MYH9 (see all 60):    About MalaCards
    macrothrombocytopenia and progressive sensorineural deafness    may-hegglin anomaly    sebastian syndrome    macrothrombocytopenia
    fechtner syndrome    alport syndrome    epstein syndrome    bernard-soulier syndrome
    deafness, autosomal dominant 17    graft versus host disease    acute graft versus host disease    autosomal dominant alport syndrome
    macrothrombocytopenia progressive deafness    cleft lip/palate    focal segmental glomerulosclerosis    hearing loss
    sensorineural hearing loss    anaplastic large cell lymphoma    cleft lip    cleft palate

    5 diseases from the University of Copenhagen DISEASES database for MYH9:
    Thrombocytopenia     Sensorineural hearing loss     Bernard-Soulier syndrome     Kidney disease
    Alport syndrome

    10/28 Novoseek disease relationships for MYH9 gene (see all 28)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    may-hegglin anomaly 97.7 30 12930685 (2), 19954613 (1), 11935325 (1), 11943476 (1) (see all 18)
    sebastian syndrome 96.9 6 11935325 (1), 19408192 (1), 10973259 (1), 11159552 (1) (see all 5)
    epsteins syndrome 96.5 11 11943476 (2), 11935325 (1), 17975807 (1), 19408192 (1) (see all 9)
    fechtner syndrome 96.3 8 11752022 (2), 17655694 (2), 18718080 (1), 19408192 (1)
    platelet disorder 82.7 5 11935325 (2), 19645626 (1), 16044442 (1)
    deafness sensorineural 75.6 3 19967157 (1), 10973259 (1), 17655694 (1)
    bernard-soulier syndrome 74.8 4 15477207 (1), 14706930 (1), 14635206 (1), 15529446 (1)
    alports syndrome 73.9 2 12454218 (1), 11590545 (1)
    nephritis 72.1 6 17975807 (1), 19967157 (1), 16978745 (1), 19645626 (1) (see all 6)
    thrombocytopenia 69.7 18 15667538 (1), 15869600 (1), 17241369 (1), 19046415 (1) (see all 12)

    GeneTests: MYH9
    MYH9-Related Disorders

    Genetic Association Database (GAD): MYH9
    Human Genome Epidemiology (HuGE) Navigator: MYH9 (21 documents)

    Export disorders for MYH9 gene to outside databases

    Publications
    for MYH9 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MYH9 gene, integrated from 9 sources (see all 301):
    (articles sorted by number of sources associating them with MYH9)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9. (PubMed id 11023810)1, 2, 3, 9 Lalwani A.K....Mhatre A.N. (2000)
    2. Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes. (PubMed id 1860190)1, 2, 3, 9 Simons M.... Weir L. (1991)
    3. Immunofluorescence analysis of neutrophil nonmuscle myosin heavy chain-A in MYH9 disorders: association of subcellular localization with MYH9 mutations. (PubMed id 12533692)1, 2, 9 Kunishima S.... Saito H. (2003)
    4. Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes. (PubMed id 11752022)1, 2, 9 Arrondel C.... Heidet L. (2002)
    5. Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. (PubMed id 11590545)1, 2, 9 Heath K.E....Martignetti J.A. (2001)
    6. Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history of MYH9-related disease. (PubMed id 18059020)1, 2, 9 Pecci A....Savoia A. (2008)
    7. Macrothrombocytopenia and progressive deafness is due to a mutation in MYH9. (PubMed id 12621333)1, 2, 9 Mhatre A.N.... Lalwani A.K. (2003)
    8. Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans. (PubMed id 19177153)1, 2, 9 Freedman B.I....Bowden D.W. (2009)
    9. Epstein syndrome: another renal disorder with mutations in the nonmuscle myosin heavy chain 9 gene. (PubMed id 11935325)1, 2, 9 Seri M.... Savoia A. (2002)
    10. Identification of six novel MYH9 mutations and genotype-phenotype relationships in autosomal dominant macrothrombocytopenia with leukocyte inclusions. (PubMed id 11776386)1, 2, 9 Kunishima S....Saito H. (2001)

    External Searches for MYH9 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing MYH9 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4627 HGNC: 7579 AceView: MYH9 Ensembl:ENSG00000100345 euGenes: HUgn4627
    ECgene: MYH9 Kegg: 4627 H-InvDB: MYH9

    Other Databases showing MYH9 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MYH9 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MYH9 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MYH9 Genetics and Cytogenetics in Oncology and Haematology
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/MYH9

    Intellectual Property
    for MYH9 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MYH9 gene:
    Search GeneIP for patents involving MYH9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for MYH9 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences,