MYH9 Gene

Aliases
for MYH9 gene

Previous GC identifers: GC22M033322 GC22M034949 GC22M035001 GC22M019645

Summaries
for MYH9 gene

Genomic Views
for MYH9 gene

RefSeq DNA sequence:

NC_000022.10  NC_018933.1  NT_011520.12  

SwitchGear Promoter luciferase reporter plasmids (see all 3): MYH9 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYH9

MYH9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M036677:  view genomic region     (about GC identifiers)

Proteins
for MYH9 gene

3 PDB 3D structures from and Proteopedia for MYH9:

2LNK (3D)        3ZWH (3D)        4ETO (3D)    

Explore the universe of human proteins at neXtProt for MYH9: NX_P35579

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for MYH9
	GenScript Custom Purified and Recombinant Proteins Services for MYH9
	Novus Biologicals MYH9 Proteins
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MYH9

Gene Ontology (GO): 5/23 cellular component terms (GO ID links to tree view) (see all 23):    About this table

	EMD Millipore Mono- and Polyclonal Antibodies for the study of MYH9
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	Cell Signaling Technology (CST) Antibodies for MYH9
	Browse OriGene Antibodies OriGene Custom Antibody Services for MYH9
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	Novus Biologicals MYH9 Antibodies
	Abcam antibodies for MYH9
	Uscn Antibodies for MYH9
	ThermoFisher Antibody for MYH9

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MYH9
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for MYH9

Protein Domains /
Families
for MYH9 gene

ProtoNet protein and cluster: P35579

Function
for MYH9 gene

miRNA Products:		miRTarBase miRNAs that target MYH9: hsa-mir-124 (MIRT002579)
		OriGene 3'-UTR Clone: MYH9 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYH9
		8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate MYH9 (see all 47):
		hsa-miR-194* hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-300 hsa-miR-376b hsa-miR-25 hsa-miR-449a hsa-miR-10b*
		SwitchGear 3'UTR luciferase reporter plasmid: MYH9 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYH9 (see all 7) OriGene shRNA RFP: MYH9 OriGene siRNA: MYH9
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYH9

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for MYH9

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYH9 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYH9 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MYH9 (NM_002473)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MYH9
		Search LifeMap BioReagents cell lines for MYH9

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYH9

Gene Ontology (GO): 5/12 molecular function terms (GO ID links to tree view) (see all 12):    About this table

(inferred from 11 alleles) (MGI details for Myh9)

Pathways & Interactions
for MYH9 gene

	Super-pathway	contained gene-specific pathways
1	Cell adhesion_Integrin-mediated cell adhesion and migration	Cell adhesion_Integrin-mediated cell adhesion and migration 1.00 Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases 0.49 Cell adhesion Integrin-mediated cell adhesion and migration 1.00 Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases 0.49
2	Immune response _CCR3 signaling in eosinophils	Immune response _CCR3 signaling in eosinophils 1.00 Inhibitory action of Lipoxins on neutrophil migration 0.51 Immune response CCR3 signaling in eosinophils 1.00
3	Regulation of actin dynamics for phagocytic cup formation	Regulation of actin dynamics for phagocytic cup formation 1.00 Fcgamma receptor (FCGR) dependent phagocytosis 0.80 Role of myosins in phagosome formation 0.80
4	PAK Pathway	PAK Pathway 1.00 Epithelial Adherens Junctions 0.36 Antioxidant Action of Vitamin-C 0.56
5	Sema4D in semaphorin signaling	Sema4D in semaphorin signaling 1.00 Semaphorin interactions 0.44 Sema4D induced cell migration and growth-cone collapse 0.83

5 EMD Millipore Pathways for MYH9

	Cell adhesion Integrin-mediated cell adhesion and migration
	Cell adhesion Tight junctions
	Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
	Immune response CCR3 signaling in eosinophils
	Development MAG-dependent inhibition of neurite outgrowth

5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYH9

	RhoA Pathway
	Antioxidant Action of Vitamin-C
	Transendothelial Migration of Leukocytes
	Actin Nucleation by ARP-WASP Complex
	Epithelial Adherens Junctions

1 Cell Signaling Technology (CST) Pathway for MYH9

Cytoskeletal Signaling

5/6 GeneGo (Thomson Reuters) Pathways for MYH9

	Cell adhesion Integrin-mediated cell adhesion and migration
	Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
	Inhibitory action of Lipoxins on neutrophil migration
	Immune response CCR3 signaling in eosinophils
	Cell adhesion Tight junctions

5/10        Reactome Pathways for MYH9

	Developmental Biology
	Role of myosins in phagosome formation
	Fcgamma receptor (FCGR) dependent phagocytosis
	Semaphorin interactions
	Sema4D induced cell migration and growth-cone collapse

3         Kegg Pathways  (Kegg details for MYH9)

	Tight junction
	Regulation of actin cytoskeleton
	Viral myocarditis

Gene Ontology (GO): 5/26 biological process terms (GO ID links to tree view) (see all 26):    About this table

Drugs & Compounds
for MYH9 gene

Transcripts
for MYH9 gene

Expression
for MYH9 gene

MYH9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCTAAAAAA

2 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	Skeletal MuscleHyoid Arch MusclesMyoblasts			Skeletal Muscle
	Skeletal MuscleMandibular Arch MusclesMyoblasts			Skeletal Muscle
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYH9 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYH9
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYH9
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYH9

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYH9

Orthologs
for MYH9 gene

Paralogs
for MYH9 gene

Paralogs for MYH9 gene

MYH8²  MYH1²  MYH2²  MYH11²  MYH14²  MYH13²  MYH10²  MYH7B²  

MYH4²  MYH3²  MYH15²  MYH6²  MYH7²  

18/39 SIMAP similar genes for MYH9 using alignment to 6 protein entries:     MYH9_HUMAN (see all proteins) (see all similar genes):

FLJ00279    DKFZp686D10126    MYH11    MYH10    MYH14    MYO1C

MYO1E    MYO3B    MYO9B variant protein    MYH7    MYO15A    MYO9A

MYH6    MYO1H    MYH13    MYH2    MYO1G    MYH7B

MYH9 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for MYH9
PGOHUM00000263186

Genomic Variants
for MYH9 gene

10/2156 NCBI SNPs in MYH9 are shown (see all 2156)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs169966521,2	C	non-pathogenic	36696249(+)	TGGTCA/TCCTTC	2	E V	mis1 spl3		4		NA	144
rs803388351,2	C	pathogenic	36678800(-)	CCCGCC/TGAATG	2	R *	stg1		0	--	--	--	--
rs803388341,2	C	pathogenic	36680520(-)	GGACCA/GAGAAG	2	K E	mis1		0	--	--	--	--
rs803388311,2	C	pathogenic	36688106(-)	TGGACA/C/G/T          ACCTG	4	N H D Y	mis1		0	--	--	--	--
rs803388291,2	C	pathogenic	36691115(-)	CAAAAC/TGTGAG	2	R C	mis1		0	--	--	--	--
rs803388281,2	C	pathogenic	36702021(-)	CTGCCA/GCCAGG	2	H R	mis1		0	--	--	--	--
rs803388271,2	C	pathogenic	36702030(-)	CATCCA/GTATCT	2	H R	mis1		0	--	--	--	--
rs803388261,2	C	pathogenic	36702031(-)	GCATCC/TGTATC	2	R C	mis1		0	--	--	--	--
rs1419046821,2	C,	other	36689833(+)	CCAGCA/GCGGAG	2	A V	mis1		0	--	--	--	--
rs1921918811,2		--	36676888(+)	CAATCG/TTAGCT	1	--	ds5001		0	--	--	--	--

HapMap Linkage Disequilibrium report for MYH9 (36677323 - 36784063 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MYH9
     1 CNV: 5183
Human Gene Mutation Database (HGMD): MYH9

Locus Specific Mutation Databases (LSDB): MYH9

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYH9

DNA2.0 Custom Variant and Variant Library Synthesis for MYH9

Disorders / Diseases
for MYH9 gene

20/60 diseases for MYH9

10/28 Novoseek disease relationships for MYH9 gene (see all 28)    About this table

Publications
for MYH9 gene

PubMed articles for MYH9 gene, integrated from 9 sources (see all 301) (see top 10): (articles sorted by number of sources associating them with MYH9)

Utopia: connect your pdf to the dynamic world of online information

1. Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9. (PubMed id 11023810)^{1, 2, 3, 9} Lalwani A.K....Mhatre A.N. (2000)
2. Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes. (PubMed id 1860190)^{1, 2, 3, 9} Simons M.... Weir L. (1991)
3. Immunofluorescence analysis of neutrophil nonmuscle myosin heavy chain-A in MYH9 disorders: association of subcellular localization with MYH9 mutations. (PubMed id 12533692)^{1, 2, 9} Kunishima S.... Saito H. (2003)
4. Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes. (PubMed id 11752022)^{1, 2, 9} Arrondel C.... Heidet L. (2002)
5. Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. (PubMed id 11590545)^{1, 2, 9} Heath K.E....Martignetti J.A. (2001)
6. Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history of MYH9-related disease. (PubMed id 18059020)^{1, 2, 9} Pecci A....Savoia A. (2008)
7. Macrothrombocytopenia and progressive deafness is due to a mutation in MYH9. (PubMed id 12621333)^{1, 2, 9} Mhatre A.N.... Lalwani A.K. (2003)
8. Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans. (PubMed id 19177153)^{1, 2, 9} Freedman B.I....Bowden D.W. (2009)
9. Epstein syndrome: another renal disorder with mutations in the nonmuscle myosin heavy chain 9 gene. (PubMed id 11935325)^{1, 2, 9} Seri M.... Savoia A. (2002)
10. Identification of six novel MYH9 mutations and genotype-phenotype relationships in autosomal dominant macrothrombocytopenia with leukocyte inclusions. (PubMed id 11776386)^{1, 2, 9} Kunishima S....Saito H. (2001)
11. Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. (PubMed id 10973259)^{1, 2, 9} Seri M.... Martignetti J.A. (2000)
12. MYH9-related disease: may-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness. (PubMed id 12792306)^{1, 2, 9} Seri M.... Savoia A. (2003)
13. Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May- Hegglin anomaly. (PubMed id 10973260)^{1, 2, 9} Kelley M.J.... Korczak J.F. (2000)
14. MYH9 is associated with nondiabetic end-stage renal disease in African Americans. (PubMed id 18794854)^{1, 2, 9} Kao W.H....Parekh R.S. (2008)
15. MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. (PubMed id 18794856)^{1, 2, 9} Kopp J.B....Winkler C.A. (2008)
16. Asp1424Asn MYH9 mutation results in an unstable protein responsible for the phenotypes in May-Hegglin anomaly/Fechtner syndrome. (PubMed id 12649151)^{1, 2, 9} Deutsch S.... Beris P. (2003)
17. Application of a diagnostic algorithm for inherited thrombocytopenias to 46 consecutive patients. (PubMed id 15477207)^{1, 4, 9} Noris P....Balduini C.L. (2004)
18. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{1, 2} Beausoleil S.A.... Gygi S.P. (2006)
19. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
20. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{1, 2} Collins J.E.... Dunham I. (2004)
21. The DNA sequence of human chromosome 22. (PubMed id 10591208)^{1, 2} Dunham I....O'Brien K.P. (1999)
22. Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation. (PubMed id 1912569)^{1, 2} Toothaker L.E.... Tenen D.G. (1991)
23. Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation. (PubMed id 1967836)^{1, 2} Saez C.G.... Leinwand L.A. (1990)
24. Differential expression of wild-type and mutant NMMHC-IIA polypeptides in blood cells suggests cell-specific regulation mechanisms in MYH9 disorders. (PubMed id 18192507)^{1, 9} Kunishima S....Saito H. (2008)
25. Signaling via the angiotensin-converting enzyme results in the phosphorylation of the nonmuscle myosin heavy chain IIA. (PubMed id 16186248)^{1, 9} Kohlstedt K....Fleming I. (2006)
26. Pathogenetic mechanisms of hematological abnormalities of patients with MYH9 mutations. (PubMed id 16162639)^{1, 9} Pecci A....Torti M. (2005)
27. MYH9-siRNA and MYH9 mutant alleles: expression in cultured cell lines and their effects upon cell structure and function. (PubMed id 18330899)^{1, 9} Li Y....Lalwani A.K. (2008)
28. Haematological characteristics of MYH9 disorders due to MYH9 R702 mutations. (PubMed id 17241369)^{1, 9} Kunishima S....Saito H. (2007)
29. Heavy chain myosin 9-related disease (MYH9 -RD): neut rophil inclusions of myosin-9 as a pathognomonic sign of the disorder. (PubMed id 20174760)^{1, 9} Savoia A....Pecci A. (2010)
30. Analysis of clinical manifestations, mutant gene and encoded protein in two Chinese MYH9-related disease families. (PubMed id 16806139)^{1, 9} Yi Y....Ma J. (2006)
31. Genetics of focal segmental glomerulosclerosis and hu man immunodeficiency virus-associated collapsing glomerulopathy: the role of MY H9 genetic variation. (PubMed id 20347641)^{1, 9} Winkler C.A....Kopp J.B. (2010)
32. Targeted disruption of mouse ortholog of the human MYH9 responsible for macrothrombocytopenia with different organ involvement: hematological, nephrological, and otological studies of heterozygous KO mice. (PubMed id 15555549)^{1, 9} Matsushita T....Saito H. (2004)
33. Genetics, clinical and pathological features of glomerulonephritis associated with mutations of nonmuscle myosin IIA (Fechtner syndrome). (PubMed id 12500226)^{1, 9} Ghiggeri G.M....Balduini C.L. (2003)
34. Cloning of the murine non-muscle myosin heavy chain IIA gene ortholog of human MYH9 responsible for May-Hegglin, Sebastian, Fechtner, and Epstein syndromes. (PubMed id 11943476)^{1, 9} D'Apolito M....Savoia A. (2002)
35. The association of the MYH9 gene and kidney outcomes in American Indians: the Strong Heart Family Study. (PubMed id 19921264)^{1, 9} Franceschini N....Cole S.A. (2010)
36. Mutations in MYH9 exons 1, 16, 26, and 30 are infrequ ently found in Japanese patients with nonsyndromic deafness. (PubMed id 19645626)^{1, 9} Kunishima S....Saito H. (2009)
37. Identification of the first in cis mutations in MYH9 disorder. (PubMed id 19191864)^{1, 9} Miyajima Y. and Kunishima S. (2009)
38. Polymorphisms in the Nonmuscle Myosin Heavy Chain 9 Gene (MYH9) Are Associated with Albuminuria in Hypertensive African Americans: The HyperGEN Study. (PubMed id 19153477)^{1, 9} Freedman B.I....Hunt S.C. (2009)
39. High-resolution melting analysis for detection of MYH9 mutations. (PubMed id 18925516)^{1, 9} Provaznikova D....Rittich S. (2008)
40. Identification and characterization of the first large deletion of the MYH9 gene associated with MYH9 disorders. (PubMed id 18284620)^{1, 9} Kunishima S....Saito H. (2008)
41. Further evidence for the involvement of MYH9 in the etiology of non-syndromic cleft lip with or without cleft palate. (PubMed id 19320731)^{1, 9} Birnbaum S....Mangold E. (2009)
42. Clinical manifestation and molecular genetic characte rization of MYH9 disorders. (PubMed id 19557653)^{1, 9} Provaznikova D....Rittich S. (2009)
43. Identification of three in-frame deletion mutations i n MYH9 disorders suggesting an important hot spot for small rearrangements in M YH9 exon 24. (PubMed id 19459928)^{1, 9} Miyazaki K....Higashihara M. (2009)
44. [A non-familial May-Hegglin anomaly accompanying with MYH9 gene R1933X mutation and I1626V polymorphism] (PubMed id 19954613)^{1, 9} Li Y....Fang M.Y. (2009)
45. In vitro expression and characterization of MYH9 muta nt alleles linked to hereditary hearing loss. (PubMed id 20416459)^{1, 9} Wei C.C....Mhatre A.N. (2010)
46. Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. (PubMed id 18195072)^{1, 9} Morin N.A....Kim M. (2008)
47. Identification and characterization of oviductal glycoprotein-binding protein partner on gametes: epitopic similarity to non-muscle myosin IIA, MYH 9. (PubMed id 16567366)^{1, 9} Kadam K.M....Natraj U. (2006)
48. Expression of non-muscle type myosin heavy polypeptide 9 (MYH9) in mammalian cells. (PubMed id 14706930)^{1, 9} Takubo T....Hino M. (2003)
49. Immunocytochemistry for the heavy chain of the non-muscle myosin IIA as a diagnostic tool for MYH9-related disorders. (PubMed id 11918549)^{1, 9} Pecci A....Balduini C.L. (2002)
50. Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome). (PubMed id 11159552)^{1, 9} Kunishima S....Saito H. (2001)
51. Gene-gene and gene-environment interactions in HIV-as sociated nephropathy: A focus on the MYH9 nephropathy susceptibility gene. (PubMed id 20005488)^{1, 9} NA_A+ez M....Freedman B.I. (2010)
52. Association among polymorphisms at MYH9, environmenta l factors, and nonsyndromic orofacial clefts in western China. (PubMed id 19891592)^{1, 9} Jia Z.L....Shi B. (2010)
53. African ancestry allelic variation at the MYH9 gene c ontributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans. (PubMed id 20144966)^{1, 9} Behar D.M....Skorecki K. (2010)
54. MYH9 related disease: four novel mutations of the tai l domain of myosin-9 correlating with a mild clinical phenotype. (PubMed id 20002731)^{1, 9} Pecci A....Savoia A. (2010)
55. [May-Hegglin anomaly: past and present--novel diagnostic test and new concept of the disease] (PubMed id 19227191)^{1, 9} Kunishima S. (2009)
56. MYH9 related disease: a novel missense Ala95Asp mutat ion of the MYH9 gene. (PubMed id 19860543)^{1, 9} de Rocco D....Savoia A. (2009)
57. Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate. (PubMed id 18716610)^{1, 9} Chiquet B.T....Hecht J.T. (2008)
58. RASD2, MYH9, and CACNG2 Genes at Chromosome 22q12 Associated with the Subgroup of Schizophrenia with Non-Deficit in Sustained Attention and Executive Function. (PubMed id 18571626)^{1, 9} Liu Y.L....Hwu H.G. (2008)
59. Identification of the first duplication in MYH9-relat ed disease: a hot spot for unequal crossing-over within exon 24 of the MYH9 gen e. (PubMed id 19450438)^{1, 9} De Rocco D....Savoia A. (2009)
60. Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA. (PubMed id 17337617)^{1, 9} Martinelli M....Savoia A. (2007)
61. Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: relevance for MYH9-related disease. (PubMed id 16596254)^{1, 9} Marini M....Ravazzolo R. (2006)
62. A single class II myosin modulates T cell motility and stopping, but not synapse formation. (PubMed id 15064761)^{1, 9} Jacobelli J....Krummel M.F. (2004)
63. Defective expression of GPIb/IX/V complex in platelets from patients with May-Hegglin anomaly and Sebastian syndrome. (PubMed id 12217806)^{1, 9} Di Pumpo M....Balduini C.L. (2002)
64. The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA. (PubMed id 19401332)^{1, 9} Huang Y....Vogel W.F. (2009)
65. Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA. (PubMed id 18812466)^{1, 9} Chu C.C....Chiorazzi N. (2008)
66. An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character. (PubMed id 17901043)^{1, 9} Franke J.D....Kiehart D.P. (2007)
67. Cleavage of nonmuscle myosin heavy chain-A during apoptosis in human Jurkat T cells. (PubMed id 15749830)^{1, 9} Kato M....Imajoh-Ohmi S. (2005)
68. Altered cytoskeleton organization in platelets from patients with MYH9-related disease. (PubMed id 15869600)^{1, 9} Canobbio I....Torti M. (2005)
69. Non-muscle myosin heavy chain (MYH9): a new partner fused to ALK in anaplastic large cell lymphoma. (PubMed id 12800156)^{1, 9} Lamant L....Espinos E. (2003)
70. Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain. (PubMed id 14508515)^{1, 9} Obungu V.H....Marx S.J. (2003)
71. Protein complexes involving alpha v beta 3 integrins, nonmuscle myosin heavy chain-A, and focal adhesion kinase from in thrombospondin-treated smooth muscle cells. (PubMed id 10822899)^{1, 9} Sajid M....Stouffer G.A. (2000)
72. Megakaryocytes of patients with MYH9-related thromboc ytopenia present an altered proplatelet formation. (PubMed id 19572073)^{1, 9} Pecci A....Balduini A. (2009)
73. Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1alpha. (PubMed id 17327270)^{1, 9} Rey M....Sanchez-Madrid F. (2007)
74. Nonmuscle myosin IIA is associated with poor prognosis of esophageal squamous cancer. (PubMed id 21951916)¹ Xia Z.K....Hu Y.R. (2012)
75. Short-term eltrombopag for surgical preparation of a p atient with inherited thrombocytopenia deriving from MYH9 mutation. (PubMed id 22398565)¹ Pecci A....Balduini C.L. (2012)
76. A Trp33Arg mutation at exon 1 of the MYH9 gene in a Ko rean patient with May-Hegglin anomaly. (PubMed id 22477015)¹ Jang M.J....Oh D. (2012)
77. Glomerular MYH9 expression is reduced by HIV-1. (PubMed id 22313957)¹ Hays T....Klotman P.E. (2012)
78. Polymorphisms in MYH9 are associated with diabetic nep hropathy in European Americans. (PubMed id 21968013)¹ Cooke J.N....Bowden D.W. (2012)
79. Role of MYH9 and APOL1 in African and non-African popu lations with lupus nephritis. (PubMed id 22189356)¹ Lin C.P....Montgomery C.G. (2012)
80. Shotgun proteomics and network analysis of ubiquitin-r elated proteins from human breast carcinoma epithelial cells. (PubMed id 21853274)¹ Zhou J....Liang S. (2012)
81. A large family with MYH9 disorder caused by E1841K mut ation suffering from serious kidney and hearing impairment and cataracts. (PubMed id 22080149)¹ Hao J....Gao W. (2012)
82. A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
83. Sp1 phosphorylation by cyclin-dependent kinase 1/cycli n B1 represses its DNA-binding activity during mitosis in cancer cells. (PubMed id 22266860)¹ Chuang J.Y....Hung J.J. (2012)
84. Early diagnosis improves the quality of life in MYH9 disorder. (PubMed id 21796764)¹ Shiota M....Hata D. (2012)
85. Crystal structure of the S100A4-nonmuscle myosin IIA t ail fragment complex reveals an asymmetric target binding mechanism. (PubMed id 22460785)¹ Kiss B....Nyitray L. (2012)
86. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
87. Sulfiredoxin redox-sensitive interaction with S100A4 a nd non-muscle myosin IIA regulates cancer cell motility. (PubMed id 22934964)¹ Bowers R.R....Tew K.D. (2012)
88. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
89. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)¹ Wu Z....Ma L. (2012)
90. Alteration of liver enzymes is a feature of the MYH9-r elated disease syndrome. (PubMed id 22558294)¹ Pecci A....Gresele P. (2012)
91. Crawling from soft to stiff matrix polarizes the cytos keleton and phosphoregulates myosin-II heavy chain. (PubMed id 23128239)¹ Raab M....Discher D.E. (2012)
92. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
93. S100P dissociates myosin IIA filaments and focal adhes ion sites to reduce cell adhesion and enhance cell migration. (PubMed id 22399300)¹ Du M....Rudland P.S. (2012)
94. Application of the wheat-germ cell-free translation system to produce high temperature requirement A3 (HtrA3) proteases. (PubMed id 22229724)² Singh H.... Nie G. (2012)
95. Asymmetric mode of Ca^^+-S100A4 interaction with nonmu scle myosin IIA generates nanomolar affinity required for filament remodeling. (PubMed id 22483112)¹ Elliott P.R....Barsukov I.L. (2012)
96. Nonmuscle myosin IIA facilitates vesicle trafficking f or MG53-mediated cell membrane repair. (PubMed id 22253476)¹ Lin P....Ma J. (2012)
97. Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
98. Renal manifestations of patients with MYH9-related di sorders. (PubMed id 21210153)¹ Han K.H....Cheong H.I. (2011)
99. Mutations responsible for MYH9-related thrombocytopen ia impair SDF-1-driven migration of megakaryoblastic cells. (PubMed id 21833445)¹ Pecci A....Balduini C.L. (2011)
100. Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)¹ Lopitz-Otsoa F....Rodriguez M.S. (2011)
101. The population genetics of chronic kidney disease: in sights from the MYH9-APOL1 locus. (PubMed id 21537348)¹ Rosset S....Skorecki K. (2011)
102. Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression. (PubMed id 21792479)¹ Bond J.E....Levinson H. (2011)
103. Identification of proteins associated with ligand-acti vated estrogen receptor a in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. (PubMed id 21182205)¹ Tarallo R....Weisz A. (2011)
104. Identification of the myosin heavy polypeptide 9 as a downstream effector of the proprotein convertases in the human colon carcinoma H T-29 cells. (PubMed id 21805244)¹ Scamuffa N....Khatib A.M. (2011)
105. Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity. (PubMed id 22123909)¹ Sanborn K.B....Orange J.S. (2011)
106. The MYH9/APOL1 region and chronic kidney disease in E uropean-Americans. (PubMed id 21429915)¹ O'Seaghdha C.M....Kao W.H. (2011)
107. Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. (PubMed id 21698141)¹ Freedman B.I....Bowden D.W. (2011)
108. MicroRNA let-7f inhibits tumor invasion and metastasi s by targeting MYH9 in human gastric cancer. (PubMed id 21533124)¹ Liang S....Fan D. (2011)
109. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
110. Two functional S100A4 monomers are necessary for regu lating nonmuscle myosin-IIA and HCT116 cell invasion. (PubMed id 21721535)¹ House R.P....Bresnick A.R. (2011)
111. Aberrant expression of the polarity complex atypical PKC and non-muscle myosin IIA in active and inactive inflammatory bowel disease . (PubMed id 21667320)¹ Wald F.A....Salas P.J. (2011)
112. Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion. (PubMed id 21826056)¹ Erickson-Johnson M.R.... Oliveira A.M. (2011)
113. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
114. Polymorphisms in the nonmuscle myosin heavy chain 9 g ene (MYH9) are associated with the progression of IgA nephropathy in Chinese. (PubMed id 21245129)¹ Cheng W....Zhang H. (2011)
115. The role of non-muscle myosin IIA in aggregation and i nvasion of human MCF-7 breast cancer cells. (PubMed id 22161839)¹ Derycke L....Bracke M. (2011)
116. MYH9 related platelet disorders - often unknown and m isdiagnosed. (PubMed id 21567368)¹ Althaus K....Greinacher A. (2011)
117. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)¹ Emanuele M.J....Elledge S.J. (2011)
118. Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)¹ Bruderer R....Hay R.T. (2011)
119. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PubMed id 21319273)¹ Neganova I....Lako M. (2011)
120. Plasma from a case of recurrent idiopathic FSGS pertu rbs non-muscle myosin IIA (MYH9 protein) in human podocytes. (PubMed id 21380797)¹ Babayeva S....Torban E. (2011)
121. Dynamic assembly properties of nonmuscle myosin II is oforms revealed by combination of fluorescence correlation spectroscopy and flu orescence cross-correlation spectroscopy. (PubMed id 21106542)¹ Mitsuhashi M....Takahashi M. (2011)
122. Mechanism of the CaA^+-dependent interaction between S 100A4 and tail fragments of nonmuscle myosin heavy chain IIA. (PubMed id 21110983)¹ Badyal S.K....Bagshaw C.R. (2011)
123. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
124. The first report of homozygous May-Hegglin anomaly E1 841K mutation. (PubMed id 21083612)¹ Poopak B....Saki N. (2011)
125. Nonmuscle myosin IIA is required for lamellipodia for mation through binding to WAVE2 and phosphatidylinositol 3,4,5-triphosphate. (PubMed id 21184743)¹ Morimura S....Takahashi K. (2011)
126. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
127. MYH9 and APOL1 are both associated with sickle cell d isease nephropathy. (PubMed id 21910715)¹ Ashley-Koch A.E....Telen M.J. (2011)
128. Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation. (PubMed id 21081666)¹ Greco T.M....Cristea I.M. (2011)
129. A G to C transversion at the last nucleotide of exon 25 of the MYH9 gene results in a missense mutation rather than in a splicing de fect. (PubMed id 20603234)¹ Vettore S....Savoia A. (2010)
130. Genome-wide association identifies ATOH7 as a major g ene determining human optic disc size. (PubMed id 20395239)¹ Macgregor S....Mackey D.A. (2010)
131. A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. (PubMed id 20668430)¹ Genovese G....Pollak M.R. (2010)
132. Candidate genes for non-diabetic ESRD in African Amer icans: a genome-wide association study using pooled DNA. (PubMed id 20532800)¹ Bostrom M.A....Freedman B.I. (2010)
133. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)
134. Failure to find an association between myosin heavy c hain 9, non-muscle (MYH9) and schizophrenia: a three-stage case-control associa tion study. (PubMed id 20188514)¹ Amagane H....Someya T. (2010)
135. Eltrombopag for the treatment of the inherited thromb ocytopenia deriving from MYH9 mutations. (PubMed id 20844233)¹ Pecci A....Balduini C.L. (2010)
136. Potential effects of MYH9-associated nephropathy on d ialysis and kidney transplant outcomes. (PubMed id 20492585)¹ Freedman B.I. and Murea M. (2010)
137. The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)¹ Giannone R.J....Liu Y. (2010)
138. The spectrum of MYH9-associated nephropathy. (PubMed id 20299374)¹ Bostrom M.A. and Freedman B.I. (2010)
139. The value of a native milieu: mutated non-muscle myos in IIA does lead to thrombocytopenia. (PubMed id 20723023)¹ Ravid K. (2010)
140. Identification of FBXO25-interacting proteins using an integrated proteomics approach. (PubMed id 20473970)¹ Teixeira F.R.... Gomes M.D. (2010)
141. Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-1. (PubMed id 20944748)¹ Arii J....Kawaguchi Y. (2010)
142. Worldwide distribution of the MYH9 kidney disease sus ceptibility alleles and haplotypes: evidence of historical selection in Africa. (PubMed id 20634883)¹ Oleksyk T.K....Winkler C.A. (2010)
143. MYH9-related disease: Report on five German families and description of a novel mutation. (PubMed id 20221761)¹ Savoia A....Ballmaier M. (2010)
144. The non-muscle Myosin heavy chain 9 gene (MYH9) is no t associated with lupus nephritis in African Americans. (PubMed id 20523037)¹ Freedman B.I....Kimberly R.P. (2010)
145. Missense mutations in the APOL1 gene are highly assoc iated with end stage kidney disease risk previously attributed to the MYH9 gene . (PubMed id 20635188)¹ Tzur S....Skorecki K. (2010)
146. Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15. (PubMed id 20124285)¹ Nelson G.W....Winkler C.A. (2010)
147. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
148. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)¹ Yoshida T....Yamada Y. (2010)
149. Filament-associated TSGA10 protein is expressed in pr ofessional antigen presenting cells and interacts with vimentin. (PubMed id 20797700)¹ Roghanian A....Behnam B. (2010)
150. Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis. (PubMed id 20618440)¹ Pozuelo-Rubio M. (2010)
151. Interaction of c-Cbl with myosin IIA regulates Bleb a ssociated macropinocytosis of Kaposi's sarcoma-associated herpesvirus. (PubMed id 21203488)¹ Valiya Veettil M....Chandran B. (2010)
152. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)¹ Oguri M....Yamada Y. (2010)
153. Patients with Epstein-Fechtner syndromes owing to MYH 9 R702 mutations develop progressive proteinuric renal disease. (PubMed id 20200500)¹ Sekine T....Kunishima S. (2010)
154. A human MAP kinase interactome. (PubMed id 20936779)¹ Bandyopadhyay S....Ideker T. (2010)
155. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)¹ Sowa M.E....Harper J.W. (2009)
156. Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. (PubMed id 19167051)¹ Weinmann L.... Meister G. (2009)
157. Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)² Oppermann F.S.... Daub H. (2009)
158. Non-muscle myosin heavy chain 9 gene MYH9 association s in African Americans with clinically diagnosed type 2 diabetes mellitus-assoc iated ESRD. (PubMed id 19567477)¹ Freedman B.I....Bowden D.W. (2009)
159. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
160. An integrated workflow for charting the human interac tion proteome: insights into the PP2A system. (PubMed id 19156129)¹ Glatter T....Gstaiger M. (2009)
161. Charting the molecular network of the drug target Bcr-Abl. (PubMed id 19380743)¹ Brehme M....Superti-Furga G. (2009)
162. Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse . (PubMed id 19454694)¹ Sanborn K.B....Orange J.S. (2009)
163. Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion. (PubMed id 19147824)¹ Babbin B.A....Ivanov A.I. (2009)
164. Proteomics analysis of nucleolar SUMO-1 target protei ns upon proteasome inhibition. (PubMed id 19596686)¹ Matafora V....Bachi A. (2009)
165. Genome-wide linkage analysis of serum creatinine in t hree isolated European populations. (PubMed id 19387472)¹ Pattaro C....Pramstaller P.P. (2009)
166. In vitro nuclear interactome of the HIV-1 Tat protein . (PubMed id 19454010)¹ Gautier V.W....Hall W.W. (2009)
167. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)² Choudhary C.... Mann M. (2009)
168. Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. (PubMed id 18971378)¹ Breckenridge M.T....Egelhoff T.T. (2009)
169. Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography. (PubMed id 18318008)² Han G.... Gu J. (2008)
170. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
171. The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells. (PubMed id 18843042)¹ Sandquist J.C. and Means A.R. (2008)
172. Phosphoproteome of resting human platelets. (PubMed id 18088087)² Zahedi R.P.... Sickmann A. (2008)
173. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
174. Cellular nonmuscle myosins NMHC-IIA and NMHC-IIB and vertebrate heart looping. (PubMed id 18697221)¹ Lu W....Linask K.K. (2008)
175. Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes. (PubMed id 18752571)¹ Balduini A....Torti M. (2008)
176. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. (PubMed id 19367720)² Carrascal M.... Abian J. (2008)
177. Inhibition of 'self' engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. (PubMed id 18332220)¹ Tsai R.K. and Discher D.E. (2008)
178. TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. (PubMed id 18394644)¹ Clark K....van Leeuwen F.N. (2008)
179. Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. (PubMed id 18850735)¹ Fang L.... Huang L. (2008)
180. MyosinIIa contractility is required for maintenance of platelet structure during spreading on collagen and contributes to thrombus stability. (PubMed id 17645784)¹ Calaminus S.D....Watson S.P. (2007)
181. Supervillin slows cell spreading by facilitating myosin II activation at the cell periphery. (PubMed id 17925381)² Takizawa N....Luna E.J. (2007)
182. Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line. (PubMed id 17487921)² Giorgianni F.... Beranova-Giorgianni S. (2007)
183. The critical role of myosin IIA in platelet internal contraction. (PubMed id 17488351)¹ Johnson G.J....White J.G. (2007)
184. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
185. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)¹ Ewing R.M.... Figeys D. (2007)
186. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PubMed id 17620599)¹ Xiao K....Lefkowitz R.J. (2007)
187. Myosin IIA is required for cytolytic granule exocytosis in human NK cells. (PubMed id 17875677)¹ Andzelm M.M....Strominger J.L. (2007)
188. Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. (PubMed id 17310241)¹ Even-Ram S....Yamada K.M. (2007)
189. An emerin 'proteome': purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture. (PubMed id 17620012)¹ Holaska J.M. and Wilson K.L. (2007)
190. Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. (PubMed id 17567956)¹ Dulyaninova N.G....Bresnick A.R. (2007)
191. HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells. (PubMed id 17342744)¹ Dall'Era M.A....Liu A.Y. (2007)
192. Identification and characterization of proteins intera cting with Traf4, an enigmatic p53 target. (PubMed id 16969126)¹ Rozan L.M. and El-Deiry W.S. (2006)
193. Bladder exstrophy and Epstein type congenital macrothrombocytopenia: evidence for a common cause? (PubMed id 16969870)² Utsch B.... Troebs R.-B. (2006)
194. Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. (PubMed id 17020881)¹ Sandquist J.C....Means A.R. (2006)
195. The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin. (PubMed id 16403913)¹ Huang Y....Luo Y. (2006)
196. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)² Sjoeblom T.... Velculescu V.E. (2006)
197. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)
198. Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis. (PubMed id 15774463)¹ Bao J....Adelstein R.S. (2005)
199. Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PubMed id 16094384)¹ Tao W.A.... Aebersold R. (2005)
200. Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. (PubMed id 15845534)¹ Kim K.Y....Adelstein R.S. (2005)
201. Vector-capping: a simple method for preparing a high-quality full- length cDNA library. (PubMed id 16106752)¹ Kato S.... Kimura T. (2005)
202. Nucleolar proteome dynamics. (PubMed id 15635413)¹ Andersen J.S....Mann M. (2005)
203. Global phosphoproteome of HT-29 human colon adenocarcinoma cells. (PubMed id 16083285)¹ Kim J.-E.... White F.M. (2005)
204. Interaction of metastasis-inducing S100A4 protein in vivo by fluorescence lifetime imaging microscopy. (PubMed id 15289939)¹ Zhang S....Martin-Fernandez M. (2005)
205. Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. (PubMed id 16139798)² Giannakopoulos N.V....Zhang D.E. (2005)
206. Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. (PubMed id 16051665)¹ Jung S.Y....Qin J. (2005)
207. Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. (PubMed id 15865432)¹ Dulyaninova N.G....Bresnick A.R. (2005)
208. Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways. (PubMed id 16009940)¹ Zhao C.... Krug R.M. (2005)
209. MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes. (PubMed id 14594945)¹ Trinczek B....Drewes G. (2004)
210. Interaction of soluble CD163 with activated T lymphocytes involves its association with non-muscle myosin heavy chain type A. (PubMed id 15479433)¹ Timmermann M....Hogger P. (2004)
211. Heterodimeric interaction and interfaces of S100A1 an d S100P. (PubMed id 15171681)¹ Wang G....Barraclough R. (2004)
212. Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. (PubMed id 15203218)¹ Fu G.K....Stuve L.L. (2004)
213. Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin.ADP complex to actin. (PubMed id 15065866)¹ Kovacs M....Sellers J.R. (2004)
214. Mts1 regulates the assembly of nonmuscle myosin-IIA. (PubMed id 14640694)¹ Li Z.H....Bresnick A.R. (2003)
215. Myosin is an in vivo substrate of the protein tyrosine phosphatase (SHP-1) after mIgM cross-linking. (PubMed id 12705885)¹ Baba T....Hozumi N. (2003)
216. F-actin and myosin II binding domains in supervillin. (PubMed id 12917436)² Chen Y.... Luna E.J. (2003)
217. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling. (PubMed id 12577067)¹ Blagoev B....Mann M. (2003)
218. PKC epsilon is associated with myosin IIA and actin in fibroblasts. (PubMed id 11897493)¹ England K....Rumsby M. (2002)
219. Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes. (PubMed id 12421915)¹ Rey M....Sanchez-Madrid F. (2002)
220. Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function. (PubMed id 12237319)¹ Hu A....Sellers J.R. (2002)
221. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
222. Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. (PubMed id 10862698)¹ Husi H....Grant S.G. (2000)
223. Autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly) is linked to chromosome 22q12-13. (PubMed id 10914687)¹ Kelley M.J....Korczak J.F. (2000)
224. Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells. (PubMed id 11029059)¹ Wei Q. and Adelstein R.S. (2000)
225. Autosomal-dominant giant platelet syndromes: a hint of the same genetic defect as in Fechtner syndrome owing to a similar genetic linkage to chromosome 22q11-13. (PubMed id 11071640)¹ Toren A....Greinacher A. (2000)
226. Localisation of the gene responsible for fechtner syndrome in a region <600 Kb on 22q11-q13. (PubMed id 11093280)¹ Cusano R....Seri M. (2000)
227. The interface between MyBP-C and myosin: site-directed mutagenesis of the CX myosin-binding domain of MyBP-C. (PubMed id 10672519)¹ Miyamoto C.A....Reinach F.C. (1999)
228. Mapping of a myosin-binding domain and a regulatory phosphorylation site in M-protein, a structural protein of the sarcomeric M band. (PubMed id 9529381)¹ Obermann W.M....Furst D.O. (1998)
229. Effect of Mts1 on the structure and activity of nonmuscle myosin II. (PubMed id 9405067)¹ Ford H.L....Zain S.B. (1997)
230. A five-generation family with late-onset progressive hereditary hearing impairment due to cochleosaccular degeneration. (PubMed id 9390828)¹ Lalwani A.K....Luxford W.M. (1997)
231. Purification and biochemical characterization of myomesin, a myosin-binding and titin-binding protein, from bovine skeletal muscle. (PubMed id 7588733)¹ Obermann W.M....Furst D.O. (1995)
232. Cellular titin localization in stress fibers and interaction with myosin II filaments in vitro. (PubMed id 8063857)¹ Eilertsen K.J....Keller T.C. (1994)
233. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. (PubMed id 8022818)¹ Bement W.M....Mooseker M.S. (1994)
234. Differential localization of myosin-II isozymes in human cultured cells and blood cells. (PubMed id 7699007)¹ Maupin P....Pollard T.D. (1994)
235. Deafness and Heredita ry Hearing Loss Overview (PubMed id 20301607)¹ Smith R.J.H....Van Camp G. (1993)
236. MYH9-Related Disorders (PubMed id 20301740)¹ Savoia A. and Balduini C.L. (1993)
237. Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin. (PubMed id 8424456)¹ Shoeman R.L....Traub P. (1993)
238. Large tidal volume ventilation improves pulmonary gas exchange during lower abdominal surgery in Trendelenburg's position. (PubMed id 1752022)¹ Tweed W.A....Lee T.L. (1991)
239. Effect of C-protein on actomyosin ATPase. (PubMed id 6448079)¹ Moos C. and Feng I.N. (1980)
240. The interaction of C-protein with heavy meromyosin and subfragment-2. (PubMed id 352343)¹ Starr R. and Offer G. (1978)
241. Enzymic and immunochemical properties of lysozyme. Accurate definition of the antigenic site around the disulphide bridge 30-115 (site 3) by 'surface-simulation' synthesis. (PubMed id 603622)¹ Lee C.L. and Atassi M.Z. (1977)
242. [May-Hegglin anomaly--from genome research to clinical laboratory] (PubMed id 14560660)⁹ Kunishima S. (2003)
243. Absence of hearing loss in a mouse model for DFNA17 and MYH9-related disease: the use of public gene-targeted ES cell resources. (PubMed id 16630581)⁹ Parker L.L....Zuo J. (2006)
244. Detection of unique neutrophil non-muscle myosin heavy chain-A localization by immunofluorescence analysis in MYH9 disorder presented with macrothrombocytopenia without leukocyte inclusions and deafness. (PubMed id 15613099)⁹ Kunishima S....Saito H. (2005)
245. [Inhibition of MYH9 expression by short hairpin RNA expression vector in human umbilical vein endothelial cells (HUVEC).] (PubMed id 19068200)⁹ Huang Y.L....Yu B.Y. (2008)
246. [The MYH9 syndrome: report of a new case with a new mutation of the MYH9 gene] (PubMed id 16978745)⁹ Schleinitz N....Harle J.R. (2006)
247. [Nonmuscle myosin heavy chain 9 gene mutations related disease: a family report] (PubMed id 18458691)⁹ Hua Y....Lu X. (2008)
248. [Autosomal dominant macrothrombocytopenia with leukoc yte inclusion bodies and MYH9 disorders] (PubMed id 19489439)⁹ Kunishima S. (2009)
249. Alternative splice variants of MYH9. (PubMed id 17997715)⁹ Li Y....Mhatre A.N. (2008)
250. Transfection of the mutant MYH9 cDNA reproduces the most typical cellular phenotype of MYH9-related disease in different cell lines. (PubMed id 19046415)⁹ Panza E....Ravazzolo R. (2008)
251. First description of somatic mosaicism in MYH9 disorders. (PubMed id 15667538)⁹ Kunishima S....Saito H. (2005)
252. [Immunofluorescence localization of inclusion and identification of nonmuscle myosin heavy chain IIA in neutrophils of May-Hegglin anomaly patients] (PubMed id 12930685)⁹ Yi Y. and Zhang G.S. (2003)
253. Calcium-dependent threonine phosphorylation of nonmuscle myosin in stimulated RBL-2H3 mast cells. (PubMed id 10945986)⁹ Buxton D.B. and Adelstein R.S. (2000)
254. MYH9-related platelet disorders. (PubMed id 19408192)⁹ Althaus K. and Greinacher A. (2009)
255. Clinical and molecular genetic analysis of a family w ith macrothrombocytopenia and early onset sensorineural hearing loss. (PubMed id 19285578)⁹ Mhatre A.N....Lalwani A.K. (2009)
256. [Expression and function of non-muscle myosin-IIA in Fechtner syndrome] (PubMed id 18718080)⁹ Yang H.Y....Ruan C.G. (2008)
257. [Usefulness of immunofluorescence analysis of neutrop hil nonmuscle myosin heavy chain-A for diagnosing in two sisters with May-Heggl in anomaly] (PubMed id 19110523)⁹ Kimura N....Kunishima S. (2008)
258. Expression of Myh9 in the mammalian cochlea: localization within the stereocilia. (PubMed id 16862555)⁹ Mhatre A.N....Lalwani A.K. (2006)
259. A unique immunofluorescence method promotes accurate diagnosis in MYH9 disorders: a case report. (PubMed id 15342975)⁹ Yoshinari M....Tsuchiya S. (2004)
260. MYH9 spectrum of autosomal-dominant giant platelet syndromes: unexpected association with fibulin-1 variant-D inactivation. (PubMed id 14635206)⁹ Toren A....Rechavi G. (2003)
261. Essential hypertension and risk of nephropathy: a rea ppraisal. (PubMed id 20051853)⁹ Murea M. and Freedman B.I. (2010)
262. CKD in MYH9-related disorders. (PubMed id 19726116)⁹ Singh N....Venuto R.C. (2009)
263. Potential donor-recipient MYH9 genotype interactions in posttransplant nephrotic syndrome after pediatric kidney transplantation. (PubMed id 19764949)⁹ Freedman B.I....Reeves-Daniel A.M. (2009)
264. Historical hematology: May-Hegglin anomaly. (PubMed id 17975807)⁹ Saito H. and Kunishima S. (2008)
265. Accumulation of MYH9 mRNA at leukocyte inclusion bodi es in MYH9 disorders. (PubMed id 18616507)⁹ Kunishima S....Saito H. (2008)
266. Lipoxin A4 redistributes myosin IIA and Cdc42 in macrophages: implications for phagocytosis of apoptotic leukocytes. (PubMed id 16424219)⁹ Reville K....Godson C. (2006)
267. Myosin II in retinal pigmented epithelial cells: evidence for an association with membranous vesicles. (PubMed id 12697418)⁹ Linz-McGillem L.A. and Alliegro M.C. (2003)
268. Many chronic lymphocytic leukemia antibodies recogniz e apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications f or patient outcome and cell of origin. (PubMed id 20110421)⁹ Chu C.C....Chiorazzi N. (2010)
269. Extracellular ATP dissociates nonmuscle myosin from P 2X(7) complex: this dissociation regulates P2X(7) pore formation. (PubMed id 19494237)⁹ Gu B.J....Wiley J.S. (2009)
270. Protein kinase CK2 regulates cytoskeletal reorganizat ion during ionizing radiation-induced senescence of human mesenchymal stem cell s. (PubMed id 19826041)⁹ Wang D. and Jang D.J. (2009)
271. Association of CD38 with nonmuscle myosin heavy chain IIA and Lck is essential for the internalization and activation of CD38. (PubMed id 17182620)⁹ Rah S.Y....Kim U.H. (2007)
272. Perioperative management of MYH9 hereditary macrothrombocytopenia (Fechtner syndrome). (PubMed id 17655694)⁹ Selleng K....Warkentin T.E. (2007)
273. [Clinical and molecular study on Fechtner syndrome--case report and literature review] (PubMed id 17649707)⁹ Yang H.Y....Ruan C.G. (2007)
274. Role of non-HLA genetic polymorphisms in graft-versus-host disease after haematopoietic stem cell transplantation. (PubMed id 16984283)⁹ Bertinetto F.E....Amoroso A. (2006)
275. Ultrastructural analysis of granulocyte inclusions in genetically confirmed MYH9-related disorders. (PubMed id 15020273)⁹ Pujol-Moix N....Espanol I. (2004)
276. IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression during phorbol ester-induced promyelocytic HL-60 differentiation. (PubMed id 15496418)⁹ Chung M.C. and Kawamoto S. (2004)
277. Donor-recipient incompatibility at CD31-codon 563 is a major risk factor for acute graft-versus-host disease after allogeneic bone marrow transplantation from a human leucocyte antigen-matched donor. (PubMed id 11564091)⁹ Balduini C.L....Locatelli F. (2001)
278. Differential expression of nonmuscle myosin II isoforms in human atherosclerotic plaque. (PubMed id 9126650)⁹ Nikol S....Weir L. (1997)
279. Susceptibility genes in common complex kidney disease . (PubMed id 19838113)⁹ Divers J. and Freedman B.I. (2010)
280. Is there a genetic basis for health disparities in hu man immunodeficiency virus disease? (PubMed id 20309925)⁹ Winkler C. (2010)
281. Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes. (PubMed id 20160060)⁹ Ofran Y....Ritz J. (2010)
282. Is collapsing C1q nephropathy another MYH9-associated kidney disease? A case report. (PubMed id 20116156)⁹ Reeves-Daniel A.M....Freedman B.I. (2010)
283. Thrombocytopenia and proteinuria. Nonmuscle myosin he avy-chain-9-related disease ( MYH9 RD) or Epstein syndrome (ES). (PubMed id 18781340)⁹ Bhatt A....Omoloja A. (2009)
284. Megakaryocyte and platelet abnormalities in a patient with a W33C mutation in the conserved SH3-like domain of myosin heavy chain II A. (PubMed id 19967157)⁹ Kahr W.H....Blanchette V.S. (2009)
285. Alport syndrome. Molecular genetic aspects. (PubMed id 19728970)⁹ Hertz J.M. (2009)
286. Hypertension-associated kidney disease: perhaps no more. (PubMed id 18923054)⁹ Freedman B.I. and Sedor J.R. (2008)
287. Renin-angiotensin system blockade is effective in reducing proteinuria of patients with progressive nephropathy caused by MYH9 mutations (Fechtner-Epstein syndrome). (PubMed id 18503011)⁹ Pecci A....Balduini C.L. (2008)
288. A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation. (PubMed id 18312684)⁹ Titulaer M.K....Luider T.M. (2008)
289. Of mice and men: Relevance of cellular and molecular characterizations of myosin IIA to MYH9-related human disease. (PubMed id 19262128)⁹ Even-Ram S. and Yamada K.M. (2007)
290. Kappa immunoglobulin light chain polymorphisms and survival after allogeneic transplantation for B-cell malignancies: a potential graft-vs-leukaemia target. (PubMed id 17212708)⁹ Etto T.L....Schwarer A.P. (2007)

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