Aliases for MYH7B Gene
External Ids for MYH7B Gene
Previous GeneCards Identifiers for MYH7B Gene
The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]
GeneCards Summary for MYH7B Gene
MYH7B (Myosin, Heavy Chain 7B, Cardiac Muscle, Beta) is a Protein Coding gene. Diseases associated with MYH7B include left ventricular noncompaction and acute monocytic leukemia. Among its related pathways are Signaling by GPCR and Regulation of actin cytoskeleton. GO annotations related to this gene include nucleotide binding and actin filament binding. An important paralog of this gene is MYH4.
UniProtKB/Swiss-Prot for MYH7B Gene
Involved in muscle contraction.