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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MYH7B Gene

protein-coding GIFtS: 52
GCID: GC20P033565

myosin, heavy chain 7B, cardiac muscle, beta

(Previous names: myosin, heavy polypeptide 7B, cardiac muscle, beta )

Explore 10 diseases affiliated with
MYH7B via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Myosin, Heavy Chain 7B, Cardiac Muscle, Beta¹ ²		Myosin Heavy Chain 7B, Cardiac Muscle Beta Isoform² ³
MYH14¹ ² ⁵		Slow A MYH14² ³
KIAA1512¹ ³ ⁵		DJ756N5.1¹
MHC14¹ ²		Myosin-7B¹
Myosin, Heavy Polypeptide 7B, Cardiac Muscle, Beta¹ ²		U937-Associated Antigen²
Antigen MLAA-21² ³		Myosin Cardiac Muscle Beta Chain³

External Ids:	HGNC: 15906¹	Entrez Gene: 57644²	Ensembl: ENSG00000078814⁷	OMIM: 609928⁵	UniProtKB: A7E2Y1³

Export aliases for MYH7B gene to outside databases

Previous GC identifers: GC20P033325 GC20P034231 GC20P034278 GC20P033026 GC20P030322

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MYH7B:

The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene

encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a

globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad

repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain

subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature

of these variants is not determined. (provided by RefSeq, Mar 2010)

UniProtKB/Swiss-Prot: MYH7B_HUMAN, A7E2Y1

Function: Involved in muscle contraction

summary for MYH7B:

Myosins are a large family of motor proteins that share the common features of ATP hydrolysis, actin binding

and potential for kinetic energy transduction. Originally isolated from muscle cells (hence the name),

almost all eukaryotic cells are now known to contain myosins. Structurally, mysoins contain a head domain

that binds to actin filaments (microfilaments) and is the site of ATP hydrolysis. The tail domain interacts

with cargo molecules, and the neck acts as a linker between the head and tail and is the site of regulatory

myosin light chain binding. There are 17 myosin families and the most well characterized is myosin II.

Myosin II is found predominantly in myocytes and mediates plus-ended movement along microfilaments. It is

involved in muscle contraction through cyclic interactions with actin-rich thin filaments, creating a

contractile force. It is regulated by phosphorylation via myosin light chain kinase (MLCK) and by

intracellular Ca2+ concentrations.

Gene Wiki entry for MYH7B

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011362.10

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MYH7B gene promoter:
AML1a Ik-3 Arnt FAC1 STAT3 Zic3 Pax-4a En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MYH7B promoter sequence

Search SABiosciences Chromatin IP Primers for MYH7B

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYH7B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.22 Ensembl cytogenetic band: 20q11.22 HGNC cytogenetic band: 20q11

MYH7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYH7B gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P033565: view genomic region (about GC identifiers)

Start:	33,543,704 bp from pter	End:	33,590,240 bp from pter
Size:	46,537 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MYH7B_HUMAN, A7E2Y1 (See protein sequence)

Recommended Name: Myosin-7B

Size: 1941 amino acids; 221388 Da

Subunit: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain

subunits (MLC) and 2 regulatory light chain subunits (MLC-2) (By similarity)

Subcellular location: Membrane; Peripheral membrane protein

Developmental stage: Found in fetal liver and brain

Miscellaneous: Expression does not vary in normal patients compared to patients with acute monocytic leukemia

Miscellaneous: The cardiac alpha isoform is a 'fast' ATPase myosin, while the beta isoform is a 'slow' ATPase

Caution: This protein sequence has been named 'Slow A' MYH14 (PubMed:11919279), but it also appears also as 'Slow B'

MYH15 within the reference

Caution: Represents a conventional myosin. This protein should not be confused with the unconventional myosin-7 (MYO7)

Sequence caution: Sequence=AAI51243.1; Type=Erroneous initiation; Sequence=BAA96036.2; Type=Erroneous initiation;

Sequence=CAI19310.2; Type=Erroneous gene model prediction; Sequence=CAI43047.2; Type=Erroneous gene model prediction;

Secondary accessions: Q5JVW7 Q6NT44 Q6NT57 Q6WG75 Q96I57 Q9NWE2 Q9P216

Alternative splicing: 3 isoforms: A7E2Y1-1 A7E2Y1-2 A7E2Y1-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MYH7B: NX_A7E2Y1

MYH7B Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065935.2

ENSEMBL proteins:

ENSP00000262873 ENSP00000395858 ENSP00000409103 ENSP00000391939 ENSP00000412594

ENSP00000396368

Human Recombinant Protein Products:

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	Uscn Proteins for MYH7B

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--
GO:0032982	myosin filament	IEA	--

MYH7B for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for MYH7B

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MYH7B for domains About GeneDecksing

5 InterPro domains/families:

IPR004009 Myosin_N

IPR000048 IQ_motif_EF-hand-BS

IPR002928 Myosin_tail

IPR015650 Myosin_1/23/4/7/8/13/15

IPR001609 Myosin_head_motor_dom

Graphical View of Domain Structure for InterPro Entry A7E2Y1

ProtoNet protein and cluster: A7E2Y1

UniProtKB/Swiss-Prot: MYH7B_HUMAN, A7E2Y1

Similarity: Contains 1 IQ domain

Similarity: Contains 1 myosin head-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MYH7B_HUMAN, A7E2Y1

Function: Involved in muscle contraction

miRNA Products:		OriGene 3'-UTR Clone: MYH7B Browse MicroRNA Expression Plasmids
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		hsa-miR-492
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYH7B

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003774	motor activity	IEA	--
GO:0003779	actin binding	IEA	--
GO:0005524	ATP binding	IEA	--

MYH7B for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for MYH7B:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

PAK Pathway

	PAK Pathway	1.00			Epithelial Adherens Junctions	0.36
	Antioxidant Action of Vitamin-C	0.56

Fc-GammaR-Mediated Phagocytosis in Macrophages

Fc-GammaR-Mediated Phagocytosis in Macrophages

1.00

RhoGDI Pathway

0.33

Actin Nucleation by ARP-WASP Complex

Actin Nucleation by ARP-WASP Complex

1.00

RhoA Pathway

0.35

Cardiomyocyte Differentiation through BMP Receptors

Cardiomyocyte Differentiation through BMP Receptors

1.00

Tight junction

Tight junction

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYH7B (see all 13)

	RhoA Pathway
	Factors Promoting Cardiogenesis in Vertebrates
	Antioxidant Action of Vitamin-C
	Transendothelial Migration of Leukocytes
	Actin Nucleation by ARP-WASP Complex

2 Kegg Pathways (Kegg details for MYH7B):

	Tight junction
	Viral myocarditis

MYH7B for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MYH7B

STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

5/23 Interacting proteins for MYH7B (A7E2Y1³ ENSP00000262873⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ESR2	Q92731³, ENSP00000343925⁴	I2D: score=1 STRING: ENSP00000343925
UBC	P0CG48³, ENSP00000344818⁴	I2D: score=1 STRING: ENSP00000344818
ACTB	ENSP00000349960⁴	STRING: ENSP00000349960
ACTG1	ENSP00000331514⁴	STRING: ENSP00000331514
CGN	ENSP00000271636⁴	STRING: ENSP00000271636

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for MYH7B available from Tocris Bioscience About this table

Compound	Action	CAS #
(R)-(+)-Blebbistatin	Selective inhibitor of myosin II. Inactive enantiomer of (�)-blebbistatin (Cat. No. 1760)	--
(S)-(-)-Blebbistatin	Selective inhibitor of myosin II. Active enantiomer of (�)-blebbistatin (Cat. No. 1760)	[856925-71-8]
(�)-Blebbistatin	Selective inhibitor of myosin II	[674289-55-5]

Search CenterWatch for drugs/clinical trials and news about MYH7B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MYH7B gene:

NM_020884.3

Unigene Cluster for MYH7B:

Myosin, heavy chain 7B, cardiac muscle, beta

Hs.414122 [show with all ESTs]

Unigene Representative Sequence: NM_020884

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000262873(uc002xbi.2) ENST00000470929(uc010gfa.1) ENST00000481922

ENST00000446156 ENST00000453028 ENST00000435272 ENST00000433934 ENST00000456649

miRNA Products:		OriGene 3'-UTR Clone: MYH7B Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYH7B
		1 QIAGEN miScript miRNA Assays for microRNA that regulate MYH7B:
		hsa-miR-492
		SwitchGear 3'UTR luciferase reporter plasmid: MYH7B 3' UTR sequence

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		GenScript: all cDNA clones in your preferred vector: MYH7B (NM_020884)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYH7B

Additional cDNA sequence:

AB040945.2 BC007808.1 BC069327.1 BC069406.1 BC151242.1

11 DOTS entries:

DT.100038434 DT.426774 DT.91999887 DT.91745239 DT.91745251 DT.95378665 DT.91745247 DT.91745237

DT.91745244 DT.91745245 DT.91745250

24/72 AceView cDNA sequences (see all 72):

BC069327 BX281886 BC069406 AJ709100 CD244305 BF926901 AU117776 AB040945

BG189104 AI160292 BF348318 BG210297 BG189675 BM723903 AI638757 BG219246

AK000947 BX413650 BC007808 AW206885 BG218249 AI968301 BE672319 BG192213

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for MYH7B (see all 11) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14a	·	14b	^	15	^	16	^	17a	·	17b	^	18a	·	18b	^	19	^	20a	·	20b	^	21a	·	21b	^
SP1:
SP2:
SP3:
SP4:																																																			-
SP5:																																																			-

ExUns:	22	^	23a	·	23b	·	23c	·	23d
SP1:
SP2:
SP3:
SP4:
SP5:			-

ECgene alternative splicing isoforms for MYH7B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MYH7B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGGAAACCC

About this image

MYH7B expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

7 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Skeletal Muscle

Mesenchymal Condensate Cells

Bone, Cartilage

Bone

Eye

Limb

Limb

Limb

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MYH7B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYH7B

SOURCE GeneReport for Unigene cluster: Hs.414122

UniProtKB/Swiss-Prot: MYH7B_HUMAN, A7E2Y1

Tissue specificity: Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly

lower expression was detected in ovary and kidney, and intermediate expression was detected in lung, pancreas, spleen

and liver

SABiosciences Custom PCR Arrays for MYH7B

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYH7B

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYH7B

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MYH7B gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MYH7B¹	myosin, heavy chain 7B, cardiac muscle, beta	78.35(n) 79.59(a)		395279 NM_204587.1 NP_989918.1
lizard (Anolis carolinensis)	Reptilia	MYH7B⁶	--	79(a)	1 ↔ 1	4(135420982-135474586)
zebrafish (Danio rerio)	Actinopterygii	myh7b¹	myosin, heavy chain 7b	69.96(n) 73.92(a)		795534 XM_001335708.3 XP_001335744.3
fruit fly (Drosophila melanogaster)	Insecta	Mhc⁶	Myosin heavy chain	52(a)	1 → many	2L(16766737-16788766)
worm (Caenorhabditis elegans)	Secernentea	unc-54⁶ myo-5⁶ (see all 6)	Myosin-4 MYOsin heavy chain structural genes family member ... (see all 6)	47(a) 47(a) (see all 6)	many ↔ many many ↔ many (see all 6)	I(14855888-14863529) V(8109031-8118110)

ENSEMBL Gene Tree for MYH7B (if available)
TreeFam Gene Tree for MYH7B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MYH7B gene

MYH8² MYH1² MYH2² MYH11² MYH14² MYH9² MYH13² MYH10²

MYH4² MYH3² MYH15² MYH6² MYH7²

18/30 SIMAP similar genes for MYH7B using alignment to 6 protein entries: MYH7B_HUMAN (see all proteins) (see all similar genes):

MYH2 MYH4 MYH8 MYH1 MYH7 MYH15

MYH3 MYH6 MYH13 MYO19 MYH16 MYH9

MYO1E MYH11 MYO10 MYO5C MYH14 CGN

MYH7B for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs75507897^1,2	C,F,	--	30323982(+)	`TTGACT/CCTTTA`	1	--	int¹		1		WA	118
rs74516190^1,2	C,F,	--	30324298(+)	`CAAGAC/TGGGTG`	1	--	ut5¹		1		WA	118
rs6120768^1,2	H	--	30324321(+)	`TATCAG/AGTGTC`	1	--	ut5¹		4		NS EA	416
rs78737890^1,2	C,	--	30325241(+)	`TTTCAA/GGGTAG`	1	--	int¹		1		NA	120
rs79162346^1,2	F,	--	30325250(+)	`AGAAAT/CCGTAT`	1	--	int¹		1		WA	118
rs10427424^1,2	C,H	--	30325290(+)	`AGTCAG/CGTCAA`	1	--	int¹		4		NS EA	416
rs76014274^1,2	C,	--	30325368(+)	`GCTACA/GTGGAG`	1	--	int¹		0	--	--	--	--
rs79752862^1,2	C,F,	--	30325605(+)	`CTGTGC/TAGAAG`	1	--	int¹		1		WA	118
rs74937561^1,2	C,F,	--	30326050(+)	`AATGAC/ATTTAC`	1	--	int¹		1		WA	118
rs11905995^1,2	C,F,A,H,	--	30326123(+)	`CAGCCG/AGGGAA`	1	--	int¹		7		NS EA NA WA	532

HapMap Linkage Disequilibrium report for MYH7B (33543704 - 33590240 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MYH7B
1 CNV: 5134
1 Indel: 40449

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MYH7B for disorders           About GeneDecksing

OMIM gene information: 609928    OMIM disorders: --

10 diseases for MYH7B:    About MalaCards

monocytic leukemia acute monocytic leukemia dilated cardiomyopathy cardiomyopathy

gallbladder cancer hermaphroditism pharyngitis leukemia

breast cancer melanoma

Human Genome Epidemiology (HuGE) Navigator: MYH7B (7 documents)

Export disorders for MYH7B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MYH7B gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with MYH7B)

Utopia: connect your pdf to the dynamic
world of online information

Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family. (PubMed id 11919279)^{1, 2, 3} Desjardins P.R....Stedman H.H. (2002)
Evolution of sarcomeric myosin heavy chain genes: evi dence from fish. (PubMed id 15014174)^{1, 3} McGuigan K....Postlethwait J.H. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)^{1, 2} Nagase T.... Ohara O. (2000)
Sp1 phosphorylation by cyclin-dependent kinase 1/cycli n B1 represses its DNA-binding activity during mitosis in cancer cells. (PubMed id 22266860)¹ Chuang J.Y....Hung J.J. (2012)
Genetic associations for activated partial thromboplas tin time and prothrombin time, their gene expression profiles, and risk of coron ary artery disease. (PubMed id 22703881)¹ Tang W....Folsom A.R. (2012)
A genome-wide association study of the Protein C antic oagulant pathway. (PubMed id 22216198)¹ Athanasiadis G....Soria J.M. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57644	HGNC: 15906	AceView: MYH7B	Ensembl:ENSG00000078814	euGenes: HUgn57644
ECgene: MYH7B	Kegg: 57644	H-InvDB: MYH7B

(According to HUGE)
About This Section

HUGE: KIAA1512

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MYH7B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MYH7B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MYH7B gene:
Search GeneIP for patents involving MYH7B

GeneCards and IP:
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myosin, heavy chain 7B, cardiac muscle, beta

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