Aliases for MYH7B Gene
External Ids for MYH7B Gene
Previous GeneCards Identifiers for MYH7B Gene
The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]
GeneCards Summary for MYH7B Gene
MYH7B (Myosin Heavy Chain 7B) is a Protein Coding gene. Diseases associated with MYH7B include Left Ventricular Noncompaction and Acute Monocytic Leukemia. Among its related pathways are PAK Pathway and Vesicle-mediated transport. GO annotations related to this gene include nucleotide binding and actin filament binding. An important paralog of this gene is MYH7.
UniProtKB/Swiss-Prot for MYH7B Gene
Involved in muscle contraction.