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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MYH13 Gene

protein-coding   GIFtS: 60
GCID: GC17M010201

myosin, heavy chain 13, skeletal muscle

(Previous names: myosin, heavy polypeptide 13, skeletal muscle )
 Explore 7 diseases affiliated with
MYH13 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MYH13    

Aliases
for MYH13 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Myosin, Heavy Chain 13, Skeletal Muscle1 2     Myosin Heavy Chain, Skeletal Muscle, Extraocular2 3
MyHC-Eo1     Extraocular Muscle Myosin Heavy Chain2
Myosin, Heavy Polypeptide 13, Skeletal Muscle1 2     Extraocular Myosin Heavy Chain2
Myosin Heavy Chain 132 3     Myosin-131

External Ids:    HGNC: 75711   Entrez Gene: 87352   Ensembl: ENSG000000067887   OMIM: 6034875   UniProtKB: Q9UKX33   

Export aliases for MYH13 gene to outside databases

Previous GC identifers: GC17M010570 GC17M011319 GC17M010147 GC17M010404 GC17M010144


Summaries
for MYH13 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: MYH13_HUMAN, Q9UKX3
Function: Muscle contraction

summary for MYH13:
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis, actin binding
and potential for kinetic energy transduction. Originally isolated from muscle cells (hence the name),
almost all eukaryotic cells are now known to contain myosins. Structurally, mysoins contain a head domain
that binds to actin filaments (microfilaments) and is the site of ATP hydrolysis. The tail domain interacts
with cargo molecules, and the neck acts as a linker between the head and tail and is the site of regulatory
myosin light chain binding. There are 17 myosin families and the most well characterized is myosin II.
Myosin II is found predominantly in myocytes and mediates plus-ended movement along microfilaments. It is
involved in muscle contraction through cyclic interactions with actin-rich thin filaments, creating a
contractile force. It is regulated by phosphorylation via myosin light chain kinase (MLCK) and by
intracellular Ca2+ concentrations.

Gene Wiki entry for MYH13


Genomic Views
for MYH13 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYH13 gene promoter:
         HOXA9B   HOXA9   Lmo2   NF-AT   IRF-2   FOXO1a   Meis-1a   NF-AT1   Meis-1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MYH13 promoter sequence
   Search SABiosciences Chromatin IP Primers for MYH13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYH13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13

MYH13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYH13 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M010201:  view genomic region     (about GC identifiers)

Start:
 10,201,401 bp from pter      End:
 10,276,447 bp from pter
Size:
 75,047 bases      Orientation:
 minus strand

Proteins
for MYH13 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MYH13_HUMAN, Q9UKX3 (See protein sequence)
Recommended Name: Myosin-13  
Size: 1938 amino acids; 223605 Da
Subunit: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain
subunits (MLC) and 2 regulatory light chain subunits (MLC-2)
Subcellular location: Cytoplasm, myofibril. Note=Thick filaments of the myofibrils
Secondary accessions: O95252

Explore the universe of human proteins at neXtProt for MYH13: NX_Q9UKX3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UKX3

    • MYH13 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003793.2  
    ENSEMBL proteins: 
     ENSP00000459873   ENSP00000404570   ENSP00000252172  

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    Uscn Proteins for MYH13

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005859muscle myosin complex TAS10388558
    GO:0030016myofibril IEA--
    GO:0032982myosin filament IEA--


    MYH13 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MYH13

    Protein Domains /
    Families
    for MYH13 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MYH13 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR004009 Myosin_N
     IPR000048 IQ_motif_EF-hand-BS
     IPR002928 Myosin_tail
     IPR015650 Myosin_1/23/4/7/8/13/15
     IPR001609 Myosin_head_motor_dom

    Graphical View of Domain Structure for InterPro Entry Q9UKX3

    ProtoNet protein and cluster: Q9UKX3

    3 Blocks protein families:
    IPB000048 IQ calmodulin-binding region
    IPB002928 Myosin tail
    IPB004009 Myosin N-terminal SH3-like domain


    UniProtKB/Swiss-Prot: MYH13_HUMAN, Q9UKX3
    Domain: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4
    heptapeptides, characteristic for alpha-helical coiled coils
    Domain: Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later
    be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2)
    Similarity: Contains 1 IQ domain
    Similarity: Contains 1 myosin head-like domain


    Function
    for MYH13 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MYH13_HUMAN, Q9UKX3
    Function: Muscle contraction

         Genatlas biochemistry entry for MYH13:
    myosin,motor contractile protein moving towards the "plus" end of actin track,heavy chain (EO myosin),expressed in
    hyperfast extra ocular and laryngeal muscles

    miRNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for MYH13

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000146microfilament motor activity TAS10388558
    GO:0003779actin binding NAS--
    GO:0005516calmodulin binding NAS--
    GO:0005524ATP binding NAS--


    MYH13 for ontologies           About GeneDecksing



    Pathways & Interactions
    for MYH13 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/13 super-pathways (see all 13) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell adhesion_Integrin-mediated cell adhesion and migration
    		Cell adhesion_Integrin-mediated cell adhesion and migration1.00
    		Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    		Cell adhesion Integrin-mediated cell adhesion and migration1.00
    		Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases0.49
    2Immune response _CCR3 signaling in eosinophils
    		Immune response _CCR3 signaling in eosinophils1.00
    		Inhibitory action of Lipoxins on neutrophil migration0.51
    		Immune response CCR3 signaling in eosinophils1.00
    3PAK Pathway
    		PAK Pathway1.00
    		Epithelial Adherens Junctions0.36
    		Antioxidant Action of Vitamin-C0.56
    4Cell adhesion Tight junctions
    		Cell adhesion Tight junctions1.00
    		Cell adhesion_Tight junctions0.99
    5Development MAG-dependent inhibition of neurite outgrowth
    		Development MAG-dependent inhibition of neurite outgrowth1.00
    		Development_MAG-dependent inhibition of neurite outgrowth0.87

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5 EMD Millipore Pathways for MYH13
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cell adhesion Tight junctions
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Immune response CCR3 signaling in eosinophils
    Development MAG-dependent inhibition of neurite outgrowth

    5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MYH13 (see all 11)
        RhoA Pathway
    Antioxidant Action of Vitamin-C
    Transendothelial Migration of Leukocytes
    Actin Nucleation by ARP-WASP Complex
    Epithelial Adherens Junctions

    5/6 GeneGo (Thomson Reuters) Pathways for MYH13 (see all 6)
        Cell adhesion Integrin-mediated cell adhesion and migration
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
    Inhibitory action of Lipoxins on neutrophil migration
    Immune response CCR3 signaling in eosinophils
    Cell adhesion Tight junctions


    2         Kegg Pathways  (Kegg details for MYH13):
        Tight junction
    Viral myocarditis


    MYH13 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MYH13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/109 Interacting proteins for MYH13 (Q9UKX32, 3 ENSP000002521724) via UniProtKB, MINT, STRING, and/or I2D (see all 109)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAQP273482, 3, ENSP000002380814MINT-7899812 MINT-7900157 I2D: score=1 STRING: ENSP00000238081
    MYL3P085902, ENSP000002923274MINT-7899812 MINT-7900157 STRING: ENSP00000292327
    YWHAZP631042, ENSP000003095034MINT-7899812 MINT-7900157 STRING: ENSP00000309503
    MYH9P355792, ENSP000002161814MINT-7899812 MINT-7900157 STRING: ENSP00000216181
    ACTBP607092, ENSP000003499604MINT-7899812 MINT-7900157 STRING: ENSP00000349960
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006936muscle contraction TAS10388558
    GO:0009267cellular response to starvation IEA--


    MYH13 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MYH13 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for MYH13 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    (R)-(+)-BlebbistatinSelective inhibitor of myosin II. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760)--
    (S)-(-)-BlebbistatinSelective inhibitor of myosin II. Active enantiomer of (±)-blebbistatin (Cat. No. 1760)[856925-71-8]
    (±)-BlebbistatinSelective inhibitor of myosin II[674289-55-5]
    Search CenterWatch for drugs/clinical trials and news about MYH13 

    Transcripts
    for MYH13 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MYH13 gene: 
    NM_003802.2  

    Unigene Cluster for MYH13:

    Myosin, heavy chain 13, skeletal muscle
    Hs.711142  [show with all ESTs]
    Unigene Representative Sequence: AF111782
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570743 ENST00000418404 ENST00000252172(uc002gmk.1 uc010vve.1 uc010vvf.1)


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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYH13 (see all 4)
    OriGene shRNA RFP: MYH13
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AF111782.2 AK294316.1 

    2 DOTS entries:

    DT.92415772  DT.75162973 

    2 AceView cDNA sequences:

    NM_003802 AF111782 

    GeneLoc Exon Structure


    Expression
    for MYH13 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MYH13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGACACCTCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MYH13 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Skeletal MuscleExtraocular MusclesMultinuclear MyocyteSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MYH13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MYH13

    SOURCE GeneReport for Unigene cluster: Hs.711142
        SABiosciences Custom PCR Arrays for MYH13
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    In Situ
    Assay Products:     
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    Orthologs
    for MYH13 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for MYH13 gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MYH131 myosin, heavy chain 13, skeletal muscle 78.65(n)
    84.73(a)    		   768487  XM_001231455.2  XP_001231456.2 
    lizard
    (Anolis carolinensis)    		 Reptilia MYH136
    		 --
    		 86(a)
    		 1 ↔ 1
    		 2(109072753-109100735)
    zebrafish
    (Danio rerio)    		 Actinopterygii CABZ01079179.16
    myhz1.36
    (see all 12)    		 myosin, heavy polypeptide 1.3, skeletal muscle
    (see all 12)    		 81(a)
    80(a)
    (see all 12)    		 possible ortholog
    possible ortholog
    (see all 12)    		 22(270520-275616)
    5(33900114-33911998)
    fruit fly
    (Drosophila melanogaster)    		 Insecta Mhc3 striated muscle contraction myosin ATPase 48(a)
    (best of 2)    		   2 36B1   --
    worm
    (Caenorhabditis elegans)    		 Secernentea F58G4.13 myosin 46(a)
    (best of 6)    		   V(8111649-8120439)   --


    ENSEMBL Gene Tree for MYH13 (if available)
    TreeFam Gene Tree for MYH13 (if available) 

    Paralogs
    for MYH13 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MYH13 gene
    MYH82  MYH12  MYH22  MYH112  MYH142  MYH92  MYH102  MYH7B2  
    MYH42  MYH32  MYH62  MYH152  MYH72  
    18/26 SIMAP similar genes for MYH13 using alignment to 2 protein entries:     MYH13_HUMAN (see all proteins) (see all similar genes):
    MYH4    MYH3    MYH2    MYH6    MYH8    MYH7
    MYH1    alpha-MHC    MYH15    MYH7B    MYH16    MYH9
    MYH11    MYO10    MYO5B    MYO5C    MYH14    DKFZp686D10126

    MYH13 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MYH13
    PGOHUM00000263185


    Genomic Variants
    for MYH13 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1415 NCBI SNPs in MYH13 are shown (see all 1415)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs755987071,2
    		C--10203694(+) GTCCGA/GCCTGG 1 -- ds50010--------
    rs1378551871,2
    		C,--10203805(+) ATGCC-/CAG   
       TAGTG    CAGTA     		1 -- ds50010--------
    rs1908472991,2
    		--10203875(+) GTTGTA/GCCAAT 1 -- ds50010--------
    rs1510723791,2
    		C,--10204177(+) GAGCC-/GGGAAT 1 -- ds50010--------
    rs1833474411,2
    		C,--10204233(+) CTCTCA/GGAGGT 1 -- ut310--------
    rs1995374631,2
    		--10204308(+) TGTACA/GTAGGA 1 -- int10--------
    rs768653021,2
    		C,F,--10204401(+) AATGGC/TGTTGT 1 -- int11Minor allele frequency- T:0.05NA 120
    rs1180574311,2
    		--10204461(+) ACAAAC/TGCCCT 1 -- int11Minor allele frequency- T:0.01NA 120
    rs116522441,2
    		C,H--10204562(+) CTGGAA/CCCACA 1 -- int16Minor allele frequency- C:0.00NS EA NA 422
    rs1488377371,2
    		--10204674(+) ACTCCC/TCCGGG 1 -- int10--------

    HapMap Linkage Disequilibrium report for MYH13 (10201401 - 10276447 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for MYH13
         1 Indel: 72791
    Human Gene Mutation Database (HGMD): MYH13

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    Disorders / Diseases
    for MYH13 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MYH13 for disorders           About GeneDecksing

    OMIM gene information: 603487    OMIM disorders: --

    7 diseases for MYH13:    About MalaCards
    hyperthyroidism    hermaphroditism    alzheimer's disease    laryngitis
    pharyngitis    esophagitis    immunodeficiency

    Human Genome Epidemiology (HuGE) Navigator: MYH13 (5 documents)

    Export disorders for MYH13 gene to outside databases

    Publications
    for MYH13 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MYH13 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with MYH13)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The human extraocular muscle myosin heavy chain gene (MYH13) maps to the cluster of fast and developmental myosin genes on chromosome 17. (PubMed id 9806854)1, 2, 3, 9 Winters L.M.... Schachat F. (1998)
    2. Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity. (PubMed id 10388558)1, 2 Weiss A.... Leinwand L.A. (1999)
    3. Slow skeletal muscle myosin-binding protein-C (MyBPC1 ) mediates recruitment of muscle-type creatine kinase (CK) to myosin. (PubMed id 21426302)1 Chen Z....Zhou H.M. (2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    5. Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis. (PubMed id 20618440)1 Pozuelo-Rubio M. (2010)
    6. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (2009)
    7. Assessment of Alzheimer's disease case-control associations using family-based methods. (PubMed id 18830724)1 Schjeide B.M....Bertram L. (2008)
    8. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
    9. A protein interaction framework for human mRNA degradation. (PubMed id 15231747)1 Lehner B. and Sanderson C.M. (2004)
    10. Phylogenetic implications of the superfast myosin in extraocular muscles. (PubMed id 12110653)1 Schachat F. and Briggs M.M. (2002)

    External Searches for MYH13 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing MYH13 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8735 HGNC: 7571 AceView: MYH13 Ensembl:ENSG00000006788 euGenes: HUgn8735
    ECgene: MYH13 Kegg: 8735 H-InvDB: MYH13

    Other Databases showing MYH13 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MYH13 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MYH13 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MYH13 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MYH13 gene:
    Search GeneIP for patents involving MYH13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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