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MYH10 Gene

protein-coding   GIFtS: 65

GC17M008318
myosin, heavy chain 10, non-muscle
(Previous names: myosin, heavy polypeptide 10, non-muscle )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
MGC134913 2
MGC134914 2
NMMHC-B 3
NMMHC-IIB 3
NMMHCB 1, 2
Descriptions
Cellular myosin heavy chain, type B 3
Myosin heavy chain 10 3
Myosin heavy chain, non-muscle IIb 3
NMMHC II-b 3
Non-muscle myosin heavy chain B 3
Non-muscle myosin heavy chain IIb 3
cellular myosin heavy chain, type B type B 2
myosin heavy chain, nonmuscle type B 2
myosin, heavy chain 10, non-muscle 2
myosin, heavy polypeptide 10, non-muscle 1, 2
near to the ATP binding region 2
nonmuscle myosin II heavy chain-B 2
nonmuscle myosin heavy chain IIB 2
nonmuscle myosin heavy chain-B 2
External Ids
HGNC: 75681
Entrez Gene: 46282
UniProtKB: P355803
Ensembl: ENSG000001330267
Search outside databases for aliases for MYH10 gene

Previous GC identifers: GC17M008754 GC17M009471 GC17M008320 GC17M008579 GC17M008580

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MYH10_HUMAN, P35580
Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized
functions such as secretion and capping

Gene Wiki entry for MYH10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the MYH10 gene  

Entrez Gene cytogenetic band: 17p13   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13

MYH10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M008318:     (about GC identifiers)

Start:
8,318,248 bp from pter
End:
8,474,804 bp from pter
Size:
156,557 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000017.9  NT_010718.15  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MYH10_HUMAN, P35580 (See protein sequence)
Recommended Name: Myosin-10  
Size: 1976 amino acids; 228999 Da
Subunit: Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali
light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with PLEKHG6
Secondary accessions: Q12989 Q149N3 Q16087
Alternative splicing: 3 isoforms:  P35580-1   P35580-2   P35580-3   

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_005955.1  

    ENSEMBL proteins: 
    ENSP00000369315 ENSP00000353590 ENSP00000379539 ENSP00000269243 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (non-muscle heavy chain Myosin)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    5/13 Gene Ontology (GO) cellular component terms (links to tree view) (see all 13 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001725 stress fiber IDA7699007
    GO:0005737 cytoplasm IDA7699007
    GO:0005819 spindle IEA--
    GO:0005886 plasma membrane IEA--
    GO:0005938 cell cortex IDA7699007
    About this table

    Antibodies for MYH10: 
    Invitrogen Antibodies for MYH10
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for MYH10
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for MYH10  (Myosin 2b)
    Antibodies from Abcam (non-muscle heavy chain Myosin), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for MYH10

    Assays for MYH10: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    4 InterPro domains/families:
     IPR004009 Myosin_N
     IPR000048 IQ_CaM_bd_region
     IPR002928 Myosin_tail
     IPR001609 Myosin_head


       GeneDecks  MYH10 for the domains selected above  
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    Graphical View of Domain Structure for InterPro Entry P35580

    ProtoNet protein and cluster: P35580

    4 Blocks protein families:
    IPB000048 IQ calmodulin-binding region
    IPB002017 Spectrin repeat
    IPB002928 Myosin tail
    IPB004009 Myosin N-terminal SH3-like domain


    UniProtKB/Swiss-Prot: MYH10_HUMAN, P35580
    Domain: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat
    pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils
    Similarity: Contains 1 IQ domain
    Similarity: Contains 1 myosin head-like domain

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (MYH10)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005964

                  Applied Biosystems Silencer® siRNAs for MYH10

                  Sigma-Aldrich siRNA for MYH10  
                         Sigma-Aldrich shRNA Panels and shRNA for MYH10  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_005964
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_005964
                                     untagged cDNA clone in CMV expression vector: NM_005964 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_005964

    UniProtKB/Swiss-Prot: MYH10_HUMAN, P35580
    Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized
    functions such as secretion and capping

    Genatlas biochemistry entry for MYH10:
    myosin,motor contractile protein moving towards the "plus" end of actin track,heavy polypeptide
    10,non muscle

    12 MGI mutant phenotypes (inferred from 7 alleles(MGI details for Myh10):

    behavior/neurologicalcraniofacialgrowth/sizelethality-postnatal
    lethality-prenatal/perinatallife span-post-weaning/agingliver/biliary systemmusclenervous system
    skeletonvision/eye

    5/7 Gene Ontology (GO) molecular function terms (links to tree view) (see all 7 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000146 microfilament motor activity IDA15845534
    GO:0000166 nucleotide binding IEA--
    GO:0005516 calmodulin binding IEA--
    GO:0005524 ATP binding NAS7782316
    GO:0030898 actin-dependent ATPase activity IDA15845534
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    1 Invitrogen iPath™ Online BioAtlas - Pathway for MYH10 (Maps provided by GeneGo):
     Regulation of actin cytoskeleton by Rho GTPases

       GeneDecks  MYH10 for the pathways selected above  
    About GeneDecksing

    5 Millipore Pathways for MYH10
     Cell adhesion Integrin-mediated cell adhesion and migration
     Cell adhesion Tight junctions
     Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
     Immune response CCR3 signaling in eosinophils
     Development MAG-dependent inhibition of neurite outgrowth

       GeneDecks  MYH10 for the pathways selected above  
    About GeneDecksing

    5 Sigma-Aldrich "Your Favorite Gene" Pathways for  MYH10  (Your Favorite Gene powered by Ingenuity) 
     Calcium Signaling
     Cellular Effects of Sildenafil (Viagra)
     Tight Junction Signaling
     Hepatic Fibrosis / Hepatic Stellate Cell Activation
     Actin Cytoskeleton Signaling

       GeneDecks  MYH10 for the pathways selected above  
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    2 Kegg Pathways  (Kegg details for MYH10):
     hsa04530 Tight junction
     hsa04810 Regulation of actin cytoskeleton

       GeneDecks  MYH10 for the pathways selected above  
    About GeneDecksing

    5/31 Interacting proteins for MYH10 (ENSP000002692433 P355801, 2) via UniProtKB, MINT, and/or STRING (see all 31 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKEQ141641, 2EBI-351758, EBI-307369 MINT-48102 EBI-351758, EBI-307369 MINT-48102
    LLGL1Q153341EBI-351758, EBI-299979
    MCCP235081EBI-351758, EBI-307531
    PAK2Q131771EBI-351758, EBI-1045887
    PRKAB1Q9Y4781EBI-351758, EBI-719769
    About this table

    5/24 Gene Ontology (GO) biological process terms (links to tree view) (see all 24 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000281 cytokinesis after mitosis IDA15774463
    GO:0001701 in utero embryonic development IEA--
    GO:0001764 neuron migration IEA--
    GO:0001778 plasma membrane repair IEA--
    GO:0006887 exocytosis IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Compounds for MYH10 available from Tocris Bioscience
    CompoundAction CAS number
    (±)-BlebbistatinSelective inhibitor of myosin II[674289-55-5]
    About this table


    2 Novoseek chemical compound relationships for MYH10 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    actomyosin 69.34 3 16901965 (1), 12605685 (1), 17023528 (1)
    atp 0.81 1 8663598 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (MYH10)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005964

                  Sigma-Aldrich siRNA for MYH10  
                         Sigma-Aldrich shRNA Panels and shRNA for MYH10  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_005964  

    REFSEQ mRNAs for MYH10 gene: 

    NM_005964.1   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_005964  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_005964
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_005964
                                     untagged cDNA clone in CMV expression vector: NM_005964 

    Additional cDNA sequence: 

    AB210026.1 AF086505.1 AK026977.1 BC000280.1 BC008968.2 BC117690.1 BC117691.1 BC144668.1 
    BC150634.1 CR602815.1 DQ925667.1 M69181.1 S67247.1 U15618.1 U34304.1 

    20 DOTS entries:

    DT.219373  DT.100821046  DT.91719949  DT.91817109  DT.102837546  DT.435880  DT.219370  DT.120920828 
    DT.40211646  DT.92434433  DT.99994616  DT.100821044  DT.92434421  DT.95235074  DT.95309574  DT.95343009 
    DT.97818271  DT.100821042  DT.75158458  DT.91955343 

    24/395 AceView cDNA sequences (see all 395 ):

    AW473979 F12205 BU735889 AI825348 AA340297 NM_005964 BQ227385 CF541342 
    AW877049 AI277790 AA490477 BE699108 N75446 F04914 BQ189148 AI129361 
    BE781189 CB243057 BX105953 BQ688008 AA029574 BF507359 BM981822 BU182128 

    highest scoring ESTs for MYH10:

    AA355800 AI382123 AL119272 BE734186 BG479223 BG723653 BU173337 S67247 U34304 M69181 

    Unigene Cluster for MYH10:

    Myosin, heavy chain 10, non-muscle
    Hs.16355  [show with all ESTs]
    Unigene Representative Sequence: AB210026


    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for MYH10 (see all 13 )

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                    -                                       
    SP4:                                                                                                                    -                                       
    SP5:                                                                                                                                                            

    ExUns: 20 ^ 21a · 21b · 21c ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26 ^ 27
    SP1:                                                                              
    SP2:                                                                              
    SP3:                                                                              
    SP4:                                                                              
    SP5:                                                                              

    About this scheme

    ECgene alternative splicing isoforms for MYH10

    4 Ensembl transcripts including schematic representations:
    ENST00000379980  ENST00000360416  ENST00000396239  ENST00000269243  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    MYH10 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for MYH10

    1 / 2 / 3

    8 probe-sets matching MYH10 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    32838_at2, 3 U95-A 1 1.00 1.00 0.92 1.15 S67247 0.80 1.00 0.91 1

    40900_at2, 3 U95-A 1 1.00 1.00 0.61 0.28 AI382123 0.80 1.00 0.91 1

    68979_g_at2, 3 U95-E 1 1.00 1.00 0.96 0.73 AA501869 0.60 1.00 0.82 1
    68976_at2, 3 U95-E 1 0.69 1.00 0.69 1.14 AA501869 0.60 1.00 0.82 1

    213067_at2, 3 U133-A 1 1.00 1.00 -- -- AI382123 0.80 1.00 0.91 1

    212372_at2, 3 U133-A 1 1.00 1.00 -- -- AK026977 0.60 1.00 0.82 1

    213067_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    212372_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  MYH10 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TACCTCTCTA

    SOURCE GeneReport for Unigene cluster: Hs.16355

    Expression variation in blood from EXPOLDB for MYH10

    UniProtKB/Swiss-Prot: MYH10_HUMAN, P35580
    Tissue specificity: In brain, isoform 1 is predominantly expresssed in cerebellum and spinal chord,
    isoform 2 in cerebrum and retina; isoform 3 is expressed in the cerebebrum and to a much lower
    extent in cerebellum

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for MYH10 gene from 5/14 species (see all 14 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    MYH101   -- myosin, heavy chain 10, non-muscle 90.22(n)
    98.94(a)
    479497  XM_845005.1  XP_850098.1 
    chimpanzee
    (Pan troglodytes)
    MYH101   -- myosin, heavy chain 10, non-muscle 99.58(n)
    100(a)
    455090  XM_511852.2  XP_511852.2 
    cow
    (Bos taurus)
    MYH101   -- myosin, heavy chain 10, non-muscle 90.77(n)
    98.58(a)
    317655  NM_174834.1  NP_777259.1 
    rat
    (Rattus norvegicus)
    Myh101   -- myosin, heavy chain 10, non-muscle 89.29(n)
    98.79(a)
    79433  NM_031520.1  NP_113708.1 
    mouse
    (Mus musculus)
    Myh101, 5 11 (40.00 cM)5
    myosin, heavy polypeptide 10, non-muscle1, 5 89.57(n)1
    99.09(a)1
    775791  NM_175260.21  NP_780469.11 
     AI8396095  AK0199695  (see all 28)
    About this table        Species with no ortholog for MYH10

    ENSEMBL Gene Tree for MYH10
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for MYH10 gene
    MYH112  MYH92  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/861 NCBI SNPs in MYH10 are shown (see all 861 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 247)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 17 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs9611,2
    A,C,F,H8319657(-) ATATAT/CAGACA 1 -- ut31 ese35Minor allele frequency- C:0.41MN EU EA WA 596
    rs116501371,2
    A,C,F,H8317926(+) AATGTA/CCTGGA 1 -- ng518Minor allele frequency- N:0.01EA NA EU WA 634
    --
    rs105201,2
    A,C,F8318991(-) CTCCCC/TATCGC 1 -- ut313Minor allele frequency- T:0.38MN EA 1634
    --
    rs9621,2
    A,C,F8319418(-) CCGACG/GA    
       
    /T/TC
    CTCAG
    1 -- ut31 ese33EA MN 4644
    --
    rs10425671,2
    A,C8319418(-) CGACTA/CCTCAG 1 -- ut31 ese31Minor allele frequency- C:0.00MN 184
    --
    rs20474871,2
    C8318990(-) TCCCCA/GTCGCC 1 -- ut310--------
    rs80674561,2
    A,C,F,H8364995(+) ACACCA/GTTACA 1 N/N syn18Minor allele frequency- G:0.02NA EU EA WA 632
    rs113741,2
    C,F,H8357626(+) ACCTTC/TGTCTG 1 T/T syn18Minor allele frequency- T:0.39MN EA EU WA NA 2342
    rs22917181,2
    F,H8348856(+) TTCTCG/AGATTC 1 S/S syn1 ese35Minor allele frequency- A:0.05EA EU WA 1902
    rs22707421,2
    H8336508(-) GAAGAG/ACGGGA 1 E/E syn1 ese34Minor allele frequency- A:0.00EU EA WA 420
    About this table

    HapMap Linkage Disequilibrium images for MYH10 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 160776

    1 Novoseek disease relationship for MYH10 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0.00 2 12874274 (1), 11244504 (1)
    About this table

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/60 PubMed articles for MYH10 gene (see all 60 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 4628 HGNC: 7568 AceView: MYH10 Ensembl:ENSG00000133026 euGenes: HUgn4628
    ECgene: MYH10 H-InvDB: MYH10
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    ATLAS Chromosomes in Cancer entry for MYH10 Genetics and Cytogenetics in Oncology and Haematology
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for MYH10:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for MYH10-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for MYH10 Antibodies for MYH10
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for MYH10 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Search for Recombinant Proteins
     Search for Antibodies
     Search for Chimera RNAi
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Antibodies & Assays for MYH10  (Myosin 2b)

     Recombinant Proteins
    (non-muscle heavy chain Myosin)
     Antibodies (non-muscle heavy chain Myosin)
     Search OriGene for MYH10
     Tocris compounds for MYH10




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Search Novus for antibodies for MYH10

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