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Aliases for MYEOV2 Gene

Aliases for MYEOV2 Gene

  • Myeloma Overexpressed 2 2 3

External Ids for MYEOV2 Gene

Previous GeneCards Identifiers for MYEOV2 Gene

  • GC02M240786
  • GC02M241065
  • GC02M232823

Summaries for MYEOV2 Gene

GeneCards Summary for MYEOV2 Gene

MYEOV2 (Myeloma Overexpressed 2) is a Protein Coding gene. Diseases associated with MYEOV2 include myeloma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYEOV2 Gene

Genomics for MYEOV2 Gene

Regulatory Elements for MYEOV2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MYEOV2 Gene

Chromosome:
2
Start:
240,126,563 bp from pter
End:
240,136,807 bp from pter
Size:
10,245 bases
Orientation:
Minus strand

Genomic View for MYEOV2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MYEOV2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYEOV2 Gene

Proteins for MYEOV2 Gene

  • Protein details for MYEOV2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WXC6-MYOV2_HUMAN
    Recommended name:
    Myeloma-overexpressed gene 2 protein
    Protein Accession:
    Q8WXC6
    Secondary Accessions:
    • Q8N110

    Protein attributes for MYEOV2 Gene

    Size:
    57 amino acids
    Molecular mass:
    6211 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MYEOV2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MYEOV2 Gene

Proteomics data for MYEOV2 Gene at MOPED

Post-translational modifications for MYEOV2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MYEOV2 Gene

No data available for DME Specific Peptides for MYEOV2 Gene

Domains & Families for MYEOV2 Gene

Protein Domains for MYEOV2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MYEOV2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8WXC6

UniProtKB/Swiss-Prot:

MYOV2_HUMAN :
  • Belongs to the MYEOV2 family.
Family:
  • Belongs to the MYEOV2 family.
genes like me logo Genes that share domains with MYEOV2: view

No data available for Gene Families for MYEOV2 Gene

Function for MYEOV2 Gene

Phenotypes for MYEOV2 Gene

GenomeRNAi human phenotypes for MYEOV2:
genes like me logo Genes that share phenotypes with MYEOV2: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MYEOV2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MYEOV2 Gene

Localization for MYEOV2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MYEOV2 Gene COMPARTMENTS Subcellular localization image for MYEOV2 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MYEOV2 Gene

Pathways & Interactions for MYEOV2 Gene

SuperPathways for MYEOV2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MYEOV2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MYEOV2 Gene

Drugs & Compounds for MYEOV2 Gene

No Compound Related Data Available

Transcripts for MYEOV2 Gene

Unigene Clusters for MYEOV2 Gene

Myeloma overexpressed 2:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MYEOV2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MYEOV2 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6
SP1: - -
SP2: - -
SP3:

Relevant External Links for MYEOV2 Gene

GeneLoc Exon Structure for
MYEOV2
ECgene alternative splicing isoforms for
MYEOV2

Expression for MYEOV2 Gene

mRNA expression in normal human tissues for MYEOV2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MYEOV2 Gene

This gene is overexpressed in Fetal Brain (34.6), Fetal ovary (8.9), and Peripheral blood mononuclear cells (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MYEOV2 Gene



SOURCE GeneReport for Unigene cluster for MYEOV2 Gene Hs.293884

genes like me logo Genes that share expression patterns with MYEOV2: view

Protein tissue co-expression partners for MYEOV2 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MYEOV2 Gene

Orthologs for MYEOV2 Gene

This gene was present in the common ancestor of animals.

Orthologs for MYEOV2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MYEOV2 35
  • 93.57 (n)
  • 100 (a)
MYEOV2 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MYEOV2 35
  • 94.15 (n)
  • 100 (a)
MYEOV2 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Myeov2 35
  • 90.64 (n)
  • 98.25 (a)
Myeov2 16
Myeov2 36
  • 96 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MYEOV2 35
  • 98.83 (n)
  • 100 (a)
MYEOV2 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Myeov2 35
  • 89.47 (n)
  • 98.25 (a)
oppossum
(Monodelphis domestica)
Mammalia MYEOV2 36
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves MYEOV2 35
  • 87.13 (n)
  • 100 (a)
MYEOV2 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MYEOV2 36
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia myeov2 35
  • 83.04 (n)
  • 98.25 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc77808 35
myeov2 36
  • 95 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG17059 36
  • 46 (a)
OneToOne
Species with no ortholog for MYEOV2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MYEOV2 Gene

ENSEMBL:
Gene Tree for MYEOV2 (if available)
TreeFam:
Gene Tree for MYEOV2 (if available)

Paralogs for MYEOV2 Gene

Pseudogenes.org Pseudogenes for MYEOV2 Gene

genes like me logo Genes that share paralogs with MYEOV2: view

No data available for Paralogs for MYEOV2 Gene

Variants for MYEOV2 Gene

Sequence variations from dbSNP and Humsavar for MYEOV2 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs747740 -- 240,133,626(+) GAGGG(C/G)CCAGA intron-variant
rs747741 -- 240,133,753(+) GGCTG(C/T)CTGCC intron-variant
rs1866646 -- 240,130,823(+) ACTCC(A/G)CATGT downstream-variant-500B, intron-variant
rs1866647 -- 240,133,108(+) GGTAA(A/G)TTAGA intron-variant
rs1866648 -- 240,133,133(+) GCTCA(C/G)GTCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MYEOV2 Gene

Variant ID Type Subtype PubMed ID
nsv876099 CNV Gain 21882294
nsv483047 CNV Loss 15286789

Variation tolerance for MYEOV2 Gene

Residual Variation Intolerance Score: 50.77% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.39; 42.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MYEOV2 Gene

HapMap Linkage Disequilibrium report
MYEOV2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYEOV2 Gene

Disorders for MYEOV2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MYEOV2 Gene - From: GeneCards

Disorder Aliases PubMed IDs
myeloma
  • multiple myeloma
- elite association

Relevant External Links for MYEOV2

Human Genome Epidemiology (HuGE) Navigator
MYEOV2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MYEOV2
genes like me logo Genes that share disorders with MYEOV2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MYEOV2 Gene

Publications for MYEOV2 Gene

  1. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. (PMID: 25737280) Murn J. … Shi Y. (Genes Dev. 2015) 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67
  4. Myeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modification. (PMID: 23776465) Ebina M. … Chiba T. (PLoS ONE 2013) 67
  5. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 67

Products for MYEOV2 Gene

Sources for MYEOV2 Gene

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