MYCL1 Gene

Aliases
for MYCL1 gene

Previous GC identifers: GC01M040392 GC01M039364 GC01M039824 GC01M039774 GC01M040030 GC01M040133 GC01M038479

Summaries
for MYCL1 gene

Genomic Views
for MYCL1 gene

RefSeq DNA sequence:

NC_000001.10  NC_018912.1  NT_032977.9  

SwitchGear Promoter luciferase reporter plasmid: MYCL1 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYCL1

MYCL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M040361:  view genomic region     (about GC identifiers)

Proteins
for MYCL1 gene

Explore the universe of human proteins at neXtProt for MYCL1: NX_P12524

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate (see all 3): MYCL1 OriGene Custom Protein Services for MYCL1
	GenScript Custom Purified and Recombinant Proteins Services for MYCL1
	Novus Biologicals MYCL1 Protein Novus Biologicals MYCL1 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MYCL1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for MYCL1 (MYCL1/L-Myc)
	Browse OriGene Antibodies OriGene Custom Antibody Services for MYCL1
	GenScript Custom Superior Antibodies Services for MYCL1
	Novus Biologicals MYCL1 Antibodies
	Search for Antibodies for MYCL1 at Abcam
	Uscn Antibodies for MYCL1
	ThermoFisher Antibodies for MYCL1

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MYCL1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for MYCL1

Protein Domains /
Families
for MYCL1 gene

ProtoNet protein and cluster: P12524

Function
for MYCL1 gene

miRNA Products:		OriGene 3'-UTR Clone (see all 3): MYCL1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MYCL1
		8/79 QIAGEN miScript miRNA Assays for microRNAs that regulate MYCL1 (see all 79):
		hsa-miR-607 hsa-miR-3607-3p hsa-miR-106a hsa-miR-93 hsa-miR-149 hsa-miR-3613-3p hsa-miR-3148 hsa-miR-20a
		SwitchGear 3'UTR luciferase reporter plasmid: MYCL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYCL1 (see all 4) OriGene shRNA RFP: MYCL1 OriGene siRNA: MYCL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYCL1

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for MYCL1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYCL1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYCL1 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): MYCL1 (NM_001033081)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYCL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYCL1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MYCL1
		Search LifeMap BioReagents cell lines for MYCL1

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCL1

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

(inferred from 2 alleles) (MGI details for Mycl1)

Pathways & Interactions
for MYCL1 gene

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

Drugs & Compounds
for MYCL1 gene

Transcripts
for MYCL1 gene

Expression
for MYCL1 gene

MYCL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTTACAAAA

4 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	OvaryPrimary FollicleGranulosa Cells			Ovary
	OvaryPrimordial FolliclePre-Granulosa Cells			Ovary
	PancreasDorsal Pancreatic BudImmature Beta Progenitor Cells			Pancreas
	PancreasVentral Pancreatic BudImmature Beta Progenitor Cells			Pancreas
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	Definitive endoderm-like cells (A scalable, suspensi...)

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYCL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYCL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYCL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYCL1

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCL1

Orthologs
for MYCL1 gene

Paralogs
for MYCL1 gene

Paralogs for MYCL1 gene

MYCN²  MYC²  

5 SIMAP similar genes for MYCL1 using alignment to 4 protein entries:     MYCL1_HUMAN (see all proteins):

MYCL2    MAX    c-myc    N-myc    WUGSC

MYCL1 for paralogs           About GeneDecksing


2 Pseudogenes.org Pseudogenes for MYCL1
PGOHUM00000241346 PGOHUM00000250084

Genomic Variants
for MYCL1 gene

10/144 NCBI SNPs in MYCL1 are shown (see all 144)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs788480561,2		--	40360655(+)	CAGAAG/AGTCAT	2	--	ds5001		1		NA	120
rs1900608751,2		--	40360773(+)	AAGTAA/GCATTT	2	--	ds5001		0	--	--	--	--
rs1158633451,2		--	40360780(+)	ATTTAT/CCCCCA	2	--	ds5001		1		WA	118
rs771032841,2	C	--	40360784(+)	ATCCCC/TATTTT	2	--	ds5001		0	--	--	--	--
rs1826467851,2		--	40360792(+)	TTTACC/TGATAA	2	--	ds5001		0	--	--	--	--
rs1865770551,2		--	40360832(+)	AAGGCG/TGCAGA	2	--	ds5001		0	--	--	--	--
rs576101911,2	C,F,	--	40361151(+)	TAAAAT/CCAGGC	2	--	ut31		4		WA CSA	124
rs603142581,2		--	40361320(+)	AAAGAC/TTCCCC	2	--	ut31		0	--	--	--	--
rs31170841,2	C,	--	40361700(+)	TGAGGT/ATACCC	2	--	ut31 ese3		3		NA WA	240
rs412975931,2	C,F,	--	40361783(-)	CCCAGC/GTGGAC	2	--	ut31		6		EU NA WA CSA	616

HapMap Linkage Disequilibrium report for MYCL1 (40361096 - 40367928 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MYCL1
     1 CNV: 3289
Human Gene Mutation Database (HGMD): MYCL1

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYCL1

DNA2.0 Custom Variant and Variant Library Synthesis for MYCL1

Disorders / Diseases
for MYCL1 gene

20/34 diseases for MYCL1

10/19 Novoseek disease relationships for MYCL1 gene (see all 19)    About this table

Publications
for MYCL1 gene

PubMed articles for MYCL1 gene, integrated from 9 sources (see all 95): (articles sorted by number of sources associating them with MYCL1)

Utopia: connect your pdf to the dynamic world of online information

1. EcoRI polymorphism of the L-myc gene in gastric cancer patients. (PubMed id 12439118)^{1, 4, 9} Dlugosz A....Starzynska T. (2002)
2. Close correlation between restriction fragment length polymorphism of L-myc gene and susceptibility to gastric cancer. (PubMed id 12507230)^{1, 4, 9} Isbir T....Camlica H. (2002)
3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
4. A new polymorphism (Ser362Thr) of the L-myc gene is not associated with lung adenocarcinoma risk and prognosis. (PubMed id 15075794)^{1, 4} Spinola M.... Dragani T.A. (2004)
5. Meta-analysis suggests association of L-myc EcoRI polymorphism with cancer prognosis. (PubMed id 15269151)^{1, 4} Spinola M....Taioli E. (2004)
6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
7. Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review). (PubMed id 12883749)^{1, 4} Xing D....Lin D. (2003)
8. Is there any correlation between restriction fragment length polymorphism of the L-MYC gene and metastasis of human nonsmall cell lung cancer? (PubMed id 12034523)^{1, 4} Yaylim I....Camlica H. (2002)
9. Association of L-myc polymorphism with lung cancer susceptibility and prognosis in relation to age-selected controls and stratified cases. (PubMed id 11955646)^{1, 4} Shih C.M....Wang Y.C. (2002)
10. L-myc genotype is associated with different susceptibility to lung cancer in smokers. (PubMed id 11802801)^{1, 4} Kumimoto H....Ishizaki K. (2002)

External Searches for MYCL1 gene

Genome Databases showing MYCL1 gene

Other Databases showing MYCL1 gene

Specialized Databases showing MYCL1 gene

Products
for MYCL1 gene