MYCBPAP Gene
protein-coding GIFtS : 46
GCID: GC17 P048585
MYCBP associated protein
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Aliasesfor MYCBPAP gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases MYCBP Associated Protein 1 2 AMY-1-Binding Protein 12 3 AMAP-11 2 3 DKFZp434N14151 AMAP12 3 5 AMY1-Associating Protein 12 AMAM-12 3 MYCBP-Associated Protein2
Export aliases for MYCBPAP gene to outside databases Previous GC identifers: GC17P049061 GC17P045940 GC17P043953
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Summariesfor MYCBPAP gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: MYBPP_HUMAN, Q8TBZ2 Function : May play a role in spermatogenesis. May be involved in synaptic processes (By similarity)
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Genomic Viewsfor MYCBPAP gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000017.10 NC_018928.1 NT_010783.15 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for MYCBPAP Other transcription factors Search SABiosciences Chromatin IP Primers for MYCBPAP Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat MYCBPAP
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17q21.33 Ensembl cytogenetic band: 17q21.33 HGNC cytogenetic band: 17q21.33 MYCBPAP Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17P048585: view genomic region
(about GC identifiers )
Start:
48,585,745 bp from pter
End:
48,608,862 bp from pter
Size:
23,118 bases
Orientation:
plus strand
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Proteinsfor MYCBPAP gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: MYBPP_HUMAN, Q8TBZ2 (See
protein sequence )Recommended Name: MYCBP-associated protein Size : 947 amino acids; 108153 Da
Subunit : Interacts with MYCBP
Subcellular location : Cytoplasm. Membrane (By similarity). Note=Colocalizes with MYCBP in the cytoplasm
Secondary accessions : A6NHJ3 Q8TDV8 Q9H0K0Explore the universe of human proteins at neXtProt for MYCBPAP: NX_Q8TBZ2 MYCBPAP Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_115509.4 ENSEMBL proteins: ENSP00000323184 ENSP00000459714 ENSP00000407719 ENSP00000407145 ENSP00000397686 ENSP00000414583 ENSP00000464992 ENSP00000465746 ENSP00000465337 ENSP00000397209 Human Recombinant Protein Products for MYCBPAP: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
MYCBPAP for ontologies About GeneDecksing MYCBPAP Antibody Products: Assay Products for MYCBPAP:
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Protein
Domains / Familiesfor MYCBPAP gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q8TBZ2
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Functionfor MYCBPAP gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: MYBPP_HUMAN, Q8TBZ2 Function : May play a role in spermatogenesis. May be involved in synaptic processes (By similarity)
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
MYCBPAP for ontologies About GeneDecksing Phenotypes: 2 GenomeRNAi human phenotypes for MYCBPAP :Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MYCBPAP (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MYCBPAP (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: MYCBPAP (NM_032133 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYCBPAP Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MYCBPAP
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBPAP
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Pathways & Interactionsfor MYCBPAP gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MYCBPAP STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)5/6 Interacting proteins for MYCBPAP (Q8TBZ2 1 , 2 , 3 ENSP00000323184 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 6 )About this table Gene Ontology (GO): 5 biological process terms (GO ID links to tree view) : About this table
MYCBPAP for ontologies About GeneDecksing
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Drugs & Compoundsfor MYCBPAP gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for MYCBPAP Search CenterWatch for drugs/clinical trials and news about MYCBPAP / MYBPP
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Transcriptsfor MYCBPAP gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for MYCBPAP gene: NM_032133.4 Unigene Cluster for MYCBPAP:
MYCBP associated protein Hs.398196 [show with all ESTs ] Unigene Representative Sequence: NM_032133 14 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000323776 (uc010wmr.2 uc002iqz.3 ) ENST00000470609 ENST00000576179 ENST00000419930 ENST00000452039 ENST00000458692 ENST00000437498 ENST00000468821 ENST00000459754 ENST00000488432 ENST00000485169 ENST00000477744 ENST00000573066 ENST00000436259 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MYCBPAP (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MYCBPAP (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: MYCBPAP (NM_032133 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYCBPAP Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MYCBPAP
Additional cDNA sequence: AB083068.1 AK127992.1 AK303041.1 AK314052.1 AL136765.1 BC028393.2 BC036358.1
8 DOTS entries : DT.101935 DT.120965957
DT.95267785 DT.70103968 DT.95280336 DT.100722323 DT.120965962 DT.92420675 24/58 AceView cDNA sequences (see all 58 ):
BM559592 AL042715 AI656008 BG037198 BP358108 BF980036 BI463480 BC028393 CD557775 BX430897 AL832225 AI249809 NM_032133 CD244016 AI824911 AB083068 BC036358 BE549952 AI142370 AW297114 BF222708 BV205581 BX106321 AL079750 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for MYCBPAP About this scheme ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18 ^ SP1 :       -       -             -                     -         SP2 :                                                     SP3 :                                                     SP4 :       -                                               SP5 :                                                    
ExUns: 19 ^ 20 SP1 :     SP2 :     SP3 :     SP4 :     SP5 :    
ECgene alternative splicing isoforms for MYCBPAP
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Expression for MYCBPAP gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section MYCBPAP expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image MYCBPAP expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Brain Choroid Plexus Brain Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See MYCBPAP Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MYCBPAP SOURCE GeneReport for Unigene cluster: Hs.398196 UniProtKB/Swiss-Prot: MYBPP_HUMAN, Q8TBZ2 Tissue specificity : Expressed specifically in testis SABiosciences Custom PCR Arrays for MYCBPAP Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MYCBPAPBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat MYCBPAP QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MYCBPAP QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MYCBPAP In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBPAP
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Orthologsfor MYCBPAP gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for MYCBPAP gene from 5/17 species (see all 17 ) About this table
ENSEMBL Gene Tree for MYCBPAP (if available)TreeFam Gene Tree for MYCBPAP (if available)
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Paralogsfor MYCBPAP gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor MYCBPAP gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 17 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for MYCBPAP (48585745 - 48608862 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for MYCBPAP 2 CNVs : 5017 5868
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing MYCBPAP
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Disorders
/ Diseasesfor MYCBPAP gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
MYCBPAP for disorders About MalaCards
MYCBPAP for disorders About GeneDecksing
OMIM gene information: 609835
OMIM disorders : --Human Genome Epidemiology (HuGE) Navigator: MYCBPAP (1 document)Export disorders for MYCBPAP gene to outside databases
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Publicationsfor MYCBPAP gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for MYCBPAP gene integrated from 9 sources : (articles sorted by number of sources associating them with MYCBPAP) Utopia : connect your pdf to the dynamic world of online information
AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. (PubMed id 12151104) 1 , 2 , 3, 9 Yukitake H.... Ariga H. (2002) Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166) 1 , 2 Wiemann S.... Poustka A. (2001) Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738) 1 Fox C.S....Borecki I.B. (2012) IRES-mediated translational control of AMAP1 expression during differentiation of monocyte U937 cells. (PubMed id 18843202) 1 Miyata M....Sabe H. (2008) Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931) 1 Ewing R.M.... Figeys D. (2007) DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196) 2 Zody M.C.... Nusbaum C. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PubMed id 12223483) 1 Yukitake H.... Ariga H. (2002)
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External Searches for MYCBPAP gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing MYCBPAP gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing MYCBPAP gene
(According to HUGE )
About This Section --
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Specialized Databases showing MYCBPAP gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for MYCBPAP Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for MYCBPAP gene: Search GeneIP for patents involving MYCBPAP GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor MYCBPAP gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for MYCBPAP OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for MYCBPAP OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MYCBPAP OriGene Protein Over-expression Lysate for MYCBPAP Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for MYCBPAP OriGene 3'-UTR Clone for MYCBPAP OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MYCBPAP OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MYCBPAP Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MYCBPAP QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing MYCBPAP QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat MYCBPAP QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat MYCBPAP QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MYCBPAP QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MYCBPAP
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MYCBPAP Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBPAP
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MYCBPAP
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Aliases for MYCBPAP
Databases for MYCBPAP
Disorders / Diseases for MYCBPAP
Domains / Families for MYCBPAP
Drugs / Compounds for MYCBPAP
Expression for MYCBPAP
Function for MYCBPAP
Genomic Views for MYCBPAP
Intellectual Property for MYCBPAP
Orthologs for MYCBPAP
Paralogs for MYCBPAP
Pathways / Interactions for MYCBPAP
Products for MYCBPAP
Proteins for MYCBPAP
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Transcripts for MYCBPAP
Variants for MYCBPAP
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