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Aliases for MYCBPAP Gene

Aliases for MYCBPAP Gene

  • MYCBP Associated Protein 2 3
  • AMAP1 3 4 6
  • AMY-1-Binding Protein 1 3 4
  • AMAM-1 3 4
  • AMAP-1 3 4
  • AMY1-Associating Protein 1 3
  • MYCBP-Associated Protein 3

External Ids for MYCBPAP Gene

Summaries for MYCBPAP Gene

GeneCards Summary for MYCBPAP Gene

MYCBPAP (MYCBP Associated Protein) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MYCBPAP Gene

  • May play a role in spermatogenesis. May be involved in synaptic processes (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYCBPAP Gene

Genomics for MYCBPAP Gene

Genomic Location for MYCBPAP Gene

Start:
50,508,384 bp from pter
End:
50,531,502 bp from pter
Size:
23,119 bases
Orientation:
Plus strand

Genomic View for MYCBPAP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MYCBPAP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYCBPAP Gene

No data available for Regulatory Elements for MYCBPAP Gene

Proteins for MYCBPAP Gene

  • Protein details for MYCBPAP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBZ2-MYBPP_HUMAN
    Recommended name:
    MYCBP-associated protein
    Protein Accession:
    Q8TBZ2
    Secondary Accessions:
    • A6NHJ3
    • Q8TDV8
    • Q9H0K0

    Protein attributes for MYCBPAP Gene

    Size:
    947 amino acids
    Molecular mass:
    108153 Da
    Quaternary structure:
    • Interacts with MYCBP.

neXtProt entry for MYCBPAP Gene

Proteomics data for MYCBPAP Gene at MOPED

Post-translational modifications for MYCBPAP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MYCBPAP Gene

Domains for MYCBPAP Gene

Protein Domains for MYCBPAP Gene

ProtoNet:
genes like me logo Genes that share domains with MYCBPAP: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MYCBPAP Gene

Function for MYCBPAP Gene

Molecular function for MYCBPAP Gene

UniProtKB/Swiss-Prot Function: May play a role in spermatogenesis. May be involved in synaptic processes (By similarity).

Gene Ontology (GO) - Molecular Function for MYCBPAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 12151104
genes like me logo Genes that share ontologies with MYCBPAP: view
genes like me logo Genes that share phenotypes with MYCBPAP: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MYCBPAP Gene

Localization for MYCBPAP Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYCBPAP Gene

Cytoplasm. Membrane. Note=Colocalizes with MYCBP in the cytoplasm. {ECO:0000250 UniProtKB:Q69CM7, ECO:0000269 PubMed:12151104}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MYCBPAP Gene COMPARTMENTS Subcellular localization image for MYCBPAP gene
Compartment Confidence
mitochondrion 2
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MYCBPAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 12151104
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with MYCBPAP: view

Pathways for MYCBPAP Gene

SuperPathways for MYCBPAP Gene

No Data Available

Gene Ontology (GO) - Biological Process for MYCBPAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007268 synaptic transmission ISS --
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEP 12151104
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with MYCBPAP: view

No data available for Pathways by source for MYCBPAP Gene

Transcripts for MYCBPAP Gene

Unigene Clusters for MYCBPAP Gene

MYCBP associated protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MYCBPAP Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18 ^
SP1: - - - -
SP2:
SP3:
SP4: -
SP5:

ExUns: 19 ^ 20
SP1:
SP2:
SP3:
SP4:
SP5:

Relevant External Links for MYCBPAP Gene

GeneLoc Exon Structure for
MYCBPAP
ECgene alternative splicing isoforms for
MYCBPAP

Expression for MYCBPAP Gene

mRNA expression in normal human tissues for MYCBPAP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MYCBPAP Gene

This gene is overexpressed in Testis (33.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MYCBPAP Gene

SOURCE GeneReport for Unigene cluster for MYCBPAP Gene Hs.398196

mRNA Expression by UniProt/SwissProt for MYCBPAP Gene

Q8TBZ2-MYBPP_HUMAN
Tissue specificity: Expressed specifically in testis.
genes like me logo Genes that share expressions with MYCBPAP: view

Orthologs for MYCBPAP Gene

This gene was present in the common ancestor of chordates.

Orthologs for MYCBPAP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MYCBPAP 36
  • 99.61 (n)
  • 99.16 (a)
MYCBPAP 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MYCBPAP 36
  • 84.36 (n)
  • 76.86 (a)
MYCBPAP 37
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MYCBPAP 36
  • 83.3 (n)
  • 76.17 (a)
MYCBPAP 37
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mycbpap 36
  • 77.31 (n)
  • 71.57 (a)
Mycbpap 16
Mycbpap 37
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MYCBPAP 37
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MYCBPAP 37
  • 43 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mycbpap 36
  • 75.56 (n)
  • 70.82 (a)
chicken
(Gallus gallus)
Aves MYCBPAP 36
  • 56.18 (n)
  • 48.15 (a)
MYCBPAP 37
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MYCBPAP 37
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mycbpap 36
  • 54.73 (n)
  • 45.25 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC101882572 36
  • 51.49 (n)
  • 38.71 (a)
mycbpap 37
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 38 (a)
OneToMany
-- 37
  • 30 (a)
OneToMany
Species with no ortholog for MYCBPAP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MYCBPAP Gene

ENSEMBL:
Gene Tree for MYCBPAP (if available)
TreeFam:
Gene Tree for MYCBPAP (if available)

Paralogs for MYCBPAP Gene

Selected SIMAP similar genes for MYCBPAP Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with MYCBPAP: view

No data available for Paralogs for MYCBPAP Gene

Variants for MYCBPAP Gene

Sequence variations from dbSNP and Humsavar for MYCBPAP Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs898450 -- 50,527,697(+) GAAGA(C/G)GGGGG intron-variant
rs898451 -- 50,527,925(+) GCCTC(C/G)TAACC intron-variant
rs898452 -- 50,528,058(+) AGCTC(A/G)TGGCA intron-variant
rs1106730 -- 50,525,051(+) GCCCC(A/C)TCATG intron-variant
rs1133818 - 50,529,176(+) CAGAG(C/G)CTGCA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MYCBPAP Gene

Variant ID Type Subtype PubMed ID
dgv3228n71 CNV Gain 21882294
nsv908600 CNV Gain 21882294
dgv3229n71 CNV Loss 21882294
nsv2082 CNV Insertion 18451855
nsv833477 CNV Loss 17160897
dgv3230n71 CNV Loss 21882294
nsv111976 CNV Loss 16902084

Relevant External Links for MYCBPAP Gene

HapMap Linkage Disequilibrium report
MYCBPAP

Disorders for MYCBPAP Gene

Relevant External Links for MYCBPAP

Genetic Association Database (GAD)
MYCBPAP
Human Genome Epidemiology (HuGE) Navigator
MYCBPAP
genes like me logo Genes that share disorders with MYCBPAP: view

No data available for UniProtKB/Swiss-Prot for MYCBPAP Gene

Publications for MYCBPAP Gene

  1. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. (PMID: 12151104) Yukitake H. … Ariga H. (Biochim. Biophys. Acta 2002) 2 3 4 23
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  3. AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PMID: 12223483) Yukitake H. … Ariga H. (J. Biol. Chem. 2002) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PMID: 17353931) Ewing R.M. … Figeys D. (Mol. Syst. Biol. 2007) 3

Products for MYCBPAP Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate MYCBPAP
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MYCBPAP
    • Block miRNA regulation of MYCBPAP using miScript Target Protectors

    Sources for MYCBPAP Gene

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