MYCBP2 Gene
protein-coding GIFtS: 55
GCID: GC13M077618
|
|
MYC binding protein 2, E3 ubiquitin protein ligase(Previous name: MYC binding protein 2 )
| |
Aliases
for MYCBP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MYC Binding Protein 2, E3 Ubiquitin Protein Ligase1 2 | | Protein Associated With Myc2 3 | | PAM1 2 3 | | FLJ101061 | | KIAA09161 3 | | MYC Binding Protein 21 | | Myc-Binding Protein 22 3 | | Probable E3 Ubiquitin-Protein Ligase MYCBP22 | | Pam/Highwire/Rpm-1 Protein2 3 | | EC 6.3.2.-3 |
Export aliases for MYCBP2 gene to outside databasesPrevious GC identifers: GC13M075417 GC13M076517 GC13M058316 |
Summaries
for MYCBP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MYCB2_HUMAN, O75592Function: Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation oftarget proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a roleduring synaptogenesis
Gene Wiki entry for MYCBP2
|
Genomic Views
for MYCBP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MYCBP2 gene promoter:
ER-alpha ISGF-3 HOXA3 AML1a C/EBPalpha Meis-1b AREB6 CHOP-10 Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MYCBP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYCBP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q22 Ensembl cytogenetic band: 13q22.3 HGNC cytogenetic band: 13q22MYCBP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M077618: view genomic region
(about GC identifiers)
Start:
|
77,618,792 bp from pter |
End:
|
77,901,185 bp from pter |
Size:
|
282,394 bases |
Orientation:
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minus strand |
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Proteins
for MYCBP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MYCB2_HUMAN, O75592 (See
protein sequence)Recommended Name: Probable E3 ubiquitin-protein ligase MYCBP2 Size: 4640 amino acids; 510084 Da
Subunit: Interacts with MYC. Interacts with TSC2 (tuberin) when TSC2 is in complex with TSC1 (hamartin). Interacts withFBXO45
Subcellular location: Nucleus
Sequence caution: Sequence=AAD39842.1; Type=Frameshift; Positions=4636; Sequence=AAH37971.1; Type=Erroneous initiation;Sequence=CAI39758.1; Type=Erroneous gene model prediction;
Secondary accessions: A6NJC6 Q5JSX8 Q5VZN6 Q6PIB6 Q9UQ11 Q9Y6E4Alternative splicing: 2 isoforms: O75592-1 O75592-2 (Derived from EST data)Explore the universe of human proteins at neXtProt for MYCBP2: NX_O75592
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75592
MYCBP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055872.4
ENSEMBL proteins: ENSP00000349892 ENSP00000413907 ENSP00000384288 ENSP00000444596 ENSP00000353197
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MYCBP2 for ontologies About GeneDecksing
MYCBP2 Antibody Products:
Assay Products for MYCBP2: |
Protein
Domains /
Families
for MYCBP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MYCBP2 for domains About GeneDecksing
5/11 InterPro domains/families (see all 11):Graphical View of Domain Structure for InterPro Entry O75592ProtoNet protein and cluster: O75592 2 Blocks protein families: IPB000408 Regulator of chromosome condensation IPB001841 Zn-finger
UniProtKB/Swiss-Prot: MYCB2_HUMAN, O75592Domain: The PHR domains are compact beta-sandwich folds composed of 11 antiparallel strands and decorated withconserved apical loops. They are likely to play a structural role and mediate interactions with substrates or partners(By similarity)Similarity: Belongs to the highwire familySimilarity: Contains 1 B box-type zinc fingerSimilarity: Contains 1 DOC domainSimilarity: Contains 1 filamin repeatSimilarity: Contains 5 RCC1 repeatsSimilarity: Contains 1 RING-type zinc finger |
Function
for MYCBP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MYCB2_HUMAN, O75592Function: Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation oftarget proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a roleduring synaptogenesisEnzyme Number (IUBMB): EC 6.3.2.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYCBP2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYCBP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MYCBP2 (NM_015057) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYCBP2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MYCBP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBP2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- | | GO:0016874 | ligase activity |
IEA | -- | | GO:0042803 | protein homodimerization activity |
IEA | -- |
MYCBP2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Mycbp2tm1.1Adia for MYCBP2
8 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Mycbp2):
MYCBP2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MYCBP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Integrated Breast Cancer Pathway | |
1  BioSystems Pathway for MYCBP2
UniProtKB/Swiss-Prot: MYCB2_HUMAN, O75592Pathway: Protein modification; protein ubiquitinationInteractions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MYCBP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 21)
5/130 Interacting proteins for MYCBP2 (O755922, 3 ENSP000003498924) via UniProtKB, MINT, STRING, and/or I2D (see all 130) About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0008045 | motor neuron axon guidance |
-- | -- | | GO:0016567 | protein ubiquitination |
IEA | -- | | GO:0021785 | branchiomotor neuron axon guidance |
IEA | -- |
MYCBP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for MYCBP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MYCBP2
4 HMDB Compounds for MYCBP2 About this table
Search CenterWatch for drugs/clinical trials and news about MYCBP2 / MYCB2
|
Transcripts
for MYCBP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MYCBP2 gene: NM_015057.4 Unigene Cluster for MYCBP2: MYC binding protein 2, E3 ubiquitin protein ligase Hs.591221 [show with all ESTs]Unigene Representative Sequence: NM_01505713 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000357337(uc001vke.3 uc001vkg.1) ENST00000429715 ENST00000485061
ENST00000482517 ENST00000462987 ENST00000466564 ENST00000498073 ENST00000486679
ENST00000474882 ENST00000491491 ENST00000407578 ENST00000544440(uc021rks.1 uc010aev.3)
ENST00000360084
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYCBP2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYCBP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MYCBP2 (NM_015057) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MYCBP2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MYCBP2 |
Additional cDNA sequence: AB020723.1 AF075587.1 AF083244.1 AK000968.1 AK023888.1 AK025250.1 AK025299.1 BC037971.2 BX647202.1 24/25 DOTS entries (see all 25): DT.445942 DT.95136320 DT.101956478 DT.100036184 DT.40111890 DT.95136323 DT.120779329 DT.92059107 DT.99940688 DT.120779348 DT.120779355 DT.100651675 DT.120779234 DT.120779243 DT.40121982 DT.435320 DT.91924201 DT.92038334 DT.95136324 DT.97786543 DT.102830145 DT.120779333 DT.91925307 DT.92068186 24/270 AceView cDNA sequences (see all 270): AA350691 N49728 BP336806 BM825734 BX093662 BU729899 AL704422 AI290115 BQ063902 BG108656 BQ049194 AL046362 AW964505 BC037971 H20266 BX647202 AL706888 AA287873 AI278706 AW663079 BU146129 AL134630 AA813697 BX641381
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MYCBP2 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31a | · | 31b | ^ | 32 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MYCBP2
|
Expression
for MYCBP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MYCBP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCAATAAAAC
About this image
See MYCBP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MYCBP2
SOURCE GeneReport for Unigene cluster: Hs.591221
UniProtKB/Swiss-Prot: MYCB2_HUMAN, O75592Tissue specificity: Expressed in all tissues examined, expression is exceptionally abundant in brain and thymus.Colocalizes with TSC1 and TSC2 along the neurites and in the growth cones. Colocalized with TSC1 in one of thefilopodial extensions at the tip of a growth cone
SABiosciences Expression via Pathway-Focused PCR Array including MYCBP2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYCBP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MYCBP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYCBP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYCBP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBP2 |
Orthologs
for MYCBP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MYCBP2 gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for MYCBP2 (if available)
TreeFam Gene Tree for MYCBP2 (if available) |
Paralogs
for MYCBP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MYCBP2 gene
3 SIMAP similar genes for MYCBP2 using alignment to 4 protein entries: MYCB2_HUMAN (see all proteins):DKFZp586G0322 HERC3 HERC6
MYCBP2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MYCBP2
PGOHUM00000235117
|
Genomic Variants
for MYCBP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MYCBP2 (77618792 - 77868792 bp, first 250kb of MYCBP2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MYCBP2
2 CNVs: 101783 3915
Human Gene Mutation Database (HGMD): MYCBP2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYCBP2 |
|
Disorders
/ Diseases
for MYCBP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MYCBP2 for disorders About GeneDecksing
OMIM gene information: 610392
OMIM disorders: --
2  diseases for MYCBP2: About MalaCardstuberous sclerosis neuronitis
Human Genome Epidemiology (HuGE) Navigator: MYCBP2 (2 documents)
Export disorders for MYCBP2 gene to outside databases
|
Publications
for MYCBP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MYCBP2 gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with MYCBP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2, 3 Dunham A.... Ross M.T. (2004)
- Identification of a large Myc-binding protein that contains RCC1-like repeats. (PubMed id 9689053)1, 2, 3 Guo Q.... Bishop J.M. (1998)
- Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development. (PubMed id 19398581)1, 2 Saiga T....Nakayama K.I. (2009)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex. (PubMed id 14559897)1, 2 Murthy V....Ramesh V. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T....Ohara O. (1998)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
|
External Searches for MYCBP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MYCBP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MYCBP2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing MYCBP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MYCBP2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MYCBP2 gene:
Search GeneIP for patents involving MYCBP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MYCBP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MYCBP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MYCBP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MYCBP2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MYCBP2 | | OriGene 3'-UTR Clone for MYCBP2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MYCBP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MYCBP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MYCBP2 | | OriGene Custom Protein Services for MYCBP2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MYCBP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MYCBP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MYCBP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MYCBP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MYCBP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MYCBP2 |
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| | | | Search Tocris compounds for MYCBP2 |
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 | | | MYCBP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBP2 |
|  |  |  | | | | Search ThermoFisher Antibodies for MYCBP2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MYCBP2 |
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