Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



MYCBP Gene

protein-coding   GIFtS: 55
GCID: GC01M039328

MYC Binding Protein

(Previous name: c-myc binding protein)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
MYC Binding Protein1 2     C-Myc-Binding Protein2
C-Myc Binding Protein1 2     AMY13
Associate Of Myc-11 2     Associate Of Myc 13
AMY-12 3     

External Ids:    HGNC: 75541   Entrez Gene: 262922   Ensembl: ENSG000002141147   OMIM: 6065355   UniProtKB: Q994173   
ORGUL members:         

Export aliases for MYCBP gene to outside databases

Previous GC identifers: GC01M039252 GC01M038336 GC01M038792 GC01M038741 GC01M038997 GC01M039101 GC01M037446


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for MYCBP Gene:
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of
C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it
translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be
involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one
protein-coding and the other probably not protein-coding, have been found for this gene. (provided by RefSeq, Nov
2011)

GeneCards Summary for MYCBP Gene:
MYCBP (MYC binding protein) is a protein-coding gene. GO annotations related to this gene include transcription coactivator activity.

UniProtKB/Swiss-Prot: MYCBP_HUMAN, Q99417
Function: May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent
transcription by MYC

Gene Wiki entry for MYCBP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the MYCBP gene promoter:
         SRF   SRF (504 AA)   AP-2gamma   NF-AT   C/EBPalpha   HFH-1   AP-2beta   AP-2alpha   NF-AT1   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMYCBP promoter sequence
   Search Chromatin IP Primers for MYCBP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MYCBP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p33-p32.2   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p33-p32.2

MYCBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYCBP gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M039328:  view genomic region     (about GC identifiers)

Start:
39,328,162 bp from pter      End:
39,347,289 bp from pter
Size:
19,128 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for MYCBP

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: MYCBP_HUMAN, Q99417 (See protein sequence)
Recommended Name: C-Myc-binding protein  
Size: 103 amino acids; 11967 Da
Subunit: Binds via its C-terminal region to the N-terminal region of MYC. Associates with AKAP1/S-AKAP84.
Interacts with MYCBPAP
1 PDB 3D structure from and Proteopedia for MYCBP:
2YY0 (3D)    
Secondary accessions: B2R4N0 Q5TA64 Q96HE2

Explore the universe of human proteins at neXtProt for MYCBP: NX_Q99417

Explore proteomics data for MYCBP at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys5, Lys20
  • Modification sites at PhosphoSitePlus

  • See MYCBP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_036465.2  
    ENSEMBL proteins: 
     ENSP00000380702  

    MYCBP Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for MYCBP
    OriGene Protein Over-expression Lysate for MYCBP
    OriGene MassSpec for MYCBP
    OriGene Custom Protein Services for MYCBP
    GenScript Custom Purified and Recombinant Proteins Services for MYCBP
    Novus Biologicals MYCBP Proteins
    Novus Biologicals MYCBP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for MYCBP
    Cloud-Clone Corp. Proteins for MYCBP

     
    Search eBioscience for Proteins for MYCBP 

     
    antibodies-online proteins for MYCBP (10 products) 

     
    antibodies-online peptides for MYCBP

    MYCBP Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MYCBP
    Novus Biologicals MYCBP Antibodies
    Abcam antibodies for MYCBP
    Cloud-Clone Corp. Antibodies for MYCBP
    Search ThermoFisher Antibodies for MYCBP
    antibodies-online antibodies for MYCBP (29 products) 

    MYCBP Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MYCBP
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MYCBP
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MYCBP
    Cloud-Clone Corp. CLIAs for MYCBP
    Search eBioscience for ELISAs for MYCBP 
    antibodies-online kits for MYCBP (13 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR026060 AMY1

    Graphical View of Domain Structure for InterPro Entry Q99417

    ProtoNet protein and cluster: Q99417

    UniProtKB/Swiss-Prot: MYCBP_HUMAN, Q99417
    Similarity: Belongs to the AMY1 family


    Find genes that share domains with MYCBP           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MYCBP_HUMAN, Q99417
    Function: May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent
    transcription by MYC

         Genatlas biochemistry entry for MYCBP:
    c-myc binding protein,mostly expressed in the cytoplasm,translocating into the nucleus of c-myc (MYC)
    expression,stimulating the activation of the E-box regulated transcription by MYC/MAX

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003713transcription coactivator activity IDA9797456
    GO:0005515protein binding IPI12151104
         
    Find genes that share ontologies with MYCBP           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MYCBP

    miRNA
    Products:
        
    miRTarBase miRNAs that target MYCBP:
    hsa-mir-93-3p (MIRT038801), hsa-mir-32-5p (MIRT028305), hsa-mir-22-3p (MIRT005505), hsa-let-7b-5p (MIRT032374), hsa-mir-122-5p (MIRT023295)

    Block miRNA regulation of human, mouse, rat MYCBP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MYCBP (see all 88):
    hsa-miR-579 hsa-miR-520f hsa-miR-361-5p hsa-miR-300 hsa-miR-4272 hsa-miR-485-3p hsa-miR-759 hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidMYCBP 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MYCBP
    Predesigned siRNA for gene silencing in human, mouse, rat MYCBP

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MYCBP

    Clone
    Products:
         
    OriGene clones in human, mouse for MYCBP (see all 6)
    OriGene ORF clones in mouse, rat for MYCBP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MYCBP (NM_015057)
    Sino Biological Human cDNA Clone for MYCBP
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYCBP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYCBP

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MYCBP
    Browse ESI BIO Cell Lines and PureStem Progenitors for MYCBP 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    MYCBP_HUMAN, Q99417: Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the
    cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus5
    cytoskeleton4
    cytosol3
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA9797456
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IEA--
    GO:0005813centrosome IDA--

    Find genes that share ontologies with MYCBP           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for MYCBP About    
    See pathways by source

    SuperPathContained pathways About
    1Notch signaling pathway (Pathway Interaction Database)
    Notch signaling pathway


    1 BioSystems Pathway for MYCBP
        Notch signaling pathway



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MYCBP
    Interactions:

        GeneGlobe Interaction Network for MYCBP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    Selected Interacting proteins for MYCBP (Q994171, 2, 3 ENSP000003807024) via UniProtKB, MINT, STRING, and/or I2D (see all 73)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGEF40Q8TER52, 3, ENSP000002986944MINT-65269 I2D: score=5 STRING: ENSP00000298694
    PTCHD2Q9P2K92, 3, ENSP000002944844MINT-65267 I2D: score=5 STRING: ENSP00000294484
    SSRP1Q089452, 3, ENSP000002784124MINT-65266 I2D: score=5 STRING: ENSP00000278412
    CFL1P235282, 3MINT-65265 I2D: score=5 
    GDF9O603832, 3MINT-65263 I2D: score=5 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IDA9797456
    GO:0007283spermatogenesis IEP12151104

    Find genes that share ontologies with MYCBP           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MYCBP



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for MYCBP gene: 
    NM_012333.4  

    Unigene Cluster for MYCBP:

    C-myc binding protein
    Hs.591506  [show with all ESTs]
    Unigene Representative Sequence: NR_037633
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397572(uc001ccs.3 uc021olq.1) ENST00000494695 ENST00000495043
    ENST00000489803 ENST00000489575 ENST00000465771 ENST00000462027
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MYCBP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MYCBP (see all 88):
    hsa-miR-579 hsa-miR-520f hsa-miR-361-5p hsa-miR-300 hsa-miR-4272 hsa-miR-485-3p hsa-miR-759 hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidMYCBP 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MYCBP
    Predesigned siRNA for gene silencing in human, mouse, rat MYCBP
    Clone
    Products:
         
    OriGene clones in human, mouse for MYCBP (see all 6)
    OriGene ORF clones in mouse, rat for MYCBP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MYCBP (NM_015057)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MYCBP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYCBP
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MYCBP
    OriGene qSTAR qPCR primer pairs in human, mouse for MYCBP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MYCBP
      QuantiTect SYBR Green Assays in human, mouse, rat MYCBP
      QuantiFast Probe-based Assays in human, mouse, rat MYCBP

    Additional mRNA sequence: 

    AB007191.2 AB451287.1 AB451419.1 AF271261.1 AK095035.1 AK311886.1 AK312811.1 BC008686.1 
    BT007109.1 CR456936.1 D50692.1 NR_037632.1 NR_037633.1 NR_037634.1 NR_037635.1 NR_037636.1 
    NR_037637.1 

    15 DOTS entries:

    DT.445919  DT.100794114  DT.95309954  DT.97845735  DT.100794113  DT.95076061  DT.121348351  DT.95076062 
    DT.97811754  DT.101975994  DT.75138988  DT.75172997  DT.121348334  DT.95076077  DT.95308659 

    Selected AceView cDNA sequences (see all 538):

    CB160441 AI076839 AI418896 AA165138 AI148118 AF271261 CB132041 AI765647 
    CA307952 BQ777715 BM791108 BU071030 BM312296 AI797354 AA581659 AA904343 
    NM_030772 AA504831 BC016668 BI770903 CR608844 NM_017821 AA352872 AA505988 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    MYCBP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCCGTGAG
    MYCBP Expression
    About this image


    MYCBP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)
             201B6
     
     Epithelial Cells
             Spinous Keratinocytes Stratified Epidermis
     
     Epidermis (Integumentary System)
             Spinous Keratinocytes Stratified Epidermis
    MYCBP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MYCBP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591506

    UniProtKB/Swiss-Prot: MYCBP_HUMAN, Q99417
    Tissue specificity: Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low
    levels in lung

        Custom PCR Arrays for MYCBP
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MYCBP
    OriGene qSTAR qPCR primer pairs in human, mouse for MYCBP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MYCBP
    QuantiTect SYBR Green Assays in human, mouse, rat MYCBP
    QuantiFast Probe-based Assays in human, mouse, rat MYCBP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for MYCBP gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mycbp1 , 5 c-myc binding protein1, 5 95.15(n)1
    97.09(a)1
      4 (57.42 cM)5
    563091  NM_019660.31  NP_062634.21 
     1239048325 
    chicken
    (Gallus gallus)
    Aves MYCBP1 c-myc binding protein 81.55(n)
    87.38(a)
      770496  XM_001232873.3  XP_001232874.2 
    lizard
    (Anolis carolinensis)
    Reptilia MYCBP6
    MYC binding protein
    79(a)
    1 ↔ 1
    GL343426.1(760973-762000)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.64912 Xenopus laevis transcribed sequence with moderate similarity more 74.85(n)    AW633953.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AL908806.12   -- 76.73(n)    AL908806.1 


    ENSEMBL Gene Tree for MYCBP (if available)
    TreeFam Gene Tree for MYCBP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for MYCBP gene

    Find genes that share paralogs with MYCBP           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for MYCBP
    PGOHUM00000249168 PGOHUM00000240024


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MYCBP
    DNA2.0 Custom Variant and Variant Library Synthesis for MYCBP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 606535    OMIM disorders: --


    Find genes that share disorders with MYCBP           About GenesLikeMe

    Genetic Association Database (GAD): MYCBP
    Human Genome Epidemiology (HuGE) Navigator: MYCBP (1 document)

    Export disorders for MYCBP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for MYCBP gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with MYCBP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC. (PubMed id 9797456)1, 2, 3, 9 Taira T.... Ariga H. (Genes Cells 1998)
    2. AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP- dependent protein kinase. (PubMed id 11483602)1, 2, 9 Furusawa M.... Ariga H. (J. Biol. Chem. 2001)
    3. AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. (PubMed id 12151104)1, 2, 9 Yukitake H.... Ariga H. (Biochim. Biophys. Acta 2002)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (Nat. Biotechnol. 2003)
    7. AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PubMed id 12223483)1, 9 Yukitake H.... Ariga H. (J. Biol. Chem. 2002)
    8. AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex. (PubMed id 12414807)1, 9 Furusawa M....Ariga H. (J. Biol. Chem. 2002)
    9. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    10. 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation. (PubMed id 23444366)1 Ichimura T....Hachiya N. (J. Cell. Sci. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 26292 HGNC: 7554 AceView: MYCBPandRHBDL2andRRAGCandGJA10 Ensembl:ENSG00000214114 euGenes: HUgn26292
    ECgene: MYCBP H-InvDB: MYCBP

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for MYCBP Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MYCBP Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for MYCBP gene:
    Search GeneIP for patents involving MYCBP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MYCBP  
     OriGene qPCR primer pairs and template standards for MYCBP   OriGene Protein Over-expression Lysate for MYCBP  
     OriGene MassSpec for MYCBP   OriGene clones in human, mouse for MYCBP  
     OriGene qSTAR qPCR primer pairs in human, mouse for MYCBP   OriGene Purified Protein for MYCBP  
     OriGene ORF clones in mouse, rat for MYCBP   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MYCBP   OriGene Custom Protein Services for MYCBP  

     
     
     Block miRNA regulation of human, mouse, rat MYCBP using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MYCBP
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MYCBP Predesigned siRNA for gene silencing in human, mouse, rat MYCBP
     QuantiFast Probe-based Assays in human, mouse, rat MYCBP QuantiTect SYBR Green Assays in human, mouse, rat MYCBP
     Custom PCR Arrays for MYCBP Search Chromatin IP Primers for MYCBP
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MYCBP  GeneGlobe Interaction Network for MYCBP
     Regulatory tfbs in MYCBP promoter
     GenScript Custom Purified and Recombinant Proteins Services for MYCBP GenScript cDNA clones with any tag delivered in your preferred vector for MYCBP
     GenScript Custom Assay Services for MYCBP GenScript Custom overexpressing Cell Line Services for MYCBP
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for MYCBP
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for MYCBP
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     MYCBP antibodies
     MYCBP proteins
     MYCBP lysates
     Antibodies for MYCBP
     See all of Abcam's Antibodies, Kits and Proteins for MYCBP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for MYCBP
     Proteins for MYCBP
     Antibodies for MYCBP
     ELISAs for MYCBP
     CLIAs for MYCBP



     Browse ESI BIO Cell Lines and PureStem Progenitors for MYCBP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MYCBP
     SwitchGear 3'UTR luciferase reporter plasmids for MYCBP
     SwitchGear Promoter luciferase reporter plasmids for MYCBP
     Search ThermoFisher Antibodies for MYCBP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MYCBP
     Browse compounds at ApexBio
     Search Addgene for plasmids for MYCBP
      Search eBioscience for proteins for MYCBP
      Search eBioscience for elisas for MYCBP
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for MYCBP
     antibodies-online antibodies for MYCBP (29 products)
     antibodies-online kits for MYCBP (13 products)
     antibodies-online peptides for MYCBP
     antibodies-online proteins for MYCBP (10 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MYCBP gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4