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MYBL2 Gene

protein-coding GIFtS: 65

GC20P041729

v-myb myeloblastosis viral oncogene homolog (avian)-like 2
(Previous name: v-myb avian myeloblastosis viral oncogene homolog-like 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
B-MYB ^¹, ²
B-Myb ^³
BMYB ^¹, ², ³, ⁵
MGC15600 ^²
OTTHUMP00000031719 ^²

Descriptions
MYB-related protein B ^²
v-myb avian myeloblastosis viral oncogene homolog-like 2 ^¹, ²
v-myb myeloblastosis viral oncogene homolog (avian)-like 2 ^²

External Ids
HGNC: 7548¹
Entrez Gene: 4605²
UniProtKB: P10244³
Ensembl: ENSG00000101057⁷

Search outside databases for aliases for MYBL2 gene

Previous GC identifers: GC20P042024 GC20P042934 GC20P042981

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MYBL2:

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a

nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by

cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both

activator and repressor activities. It has been shown to activate the cell division cycle 2,

cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist

for this gene, but their full-length natures have not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: MYBB_HUMAN, P10244

Function: Transcription factor involved in the regulation of cell survival, proliferation, and

differentiation. Transactivates the expression of the CLU gene

Gene Wiki entry for MYBL2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MYBL2 gene

Entrez Gene cytogenetic band: 20q13.1 Ensembl cytogenetic band: 20q13.12 HGNC cytogenetic band: 20q13.1

MYBL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P041729: (about GC identifiers)

Start:	41,729,123 bp from pter
End:	41,778,537 bp from pter
Size:	49,415 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000020.9 NT_011362.9

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: MYBB_HUMAN, P10244 (See protein sequence)

Recommended Name: Myb-related protein B

Size: 700 amino acids; 78764 Da

Subunit: Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5,

LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in

quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when

LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22

Subcellular location: Nucleus

Post-translational modifications:

Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in

transcriptional activity¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002457.1

ENSEMBL proteins:

ENSP00000380072 ENSP00000217026

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (B MyB)
	Human Recombinant Proteins from Abnova (MYBL2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

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Antibodies for MYBL2:

	Invitrogen Antibodies for MYBL2
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for MYBL2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (B MyB), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MYBL2)
	Novus Biologicals Antibodies for MYBL2

Assays for MYBL2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P10244

ProtoNet protein and cluster: P10244

1 Blocks protein family: IPB001005 Myb DNA-binding domain

UniProtKB/Swiss-Prot: MYBB_HUMAN, P10244

Similarity: Contains 3 HTH myb-type DNA-binding domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MYBL2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MYBL2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002466

Applied Biosystems Silencer® siRNAs for MYBL2

Sigma-Aldrich siRNA for MYBL2

Sigma-Aldrich shRNA Panels and shRNA for MYBL2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for MYBL2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002466
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002466
untagged cDNA clone in CMV expression vector: NM_002466

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002466

UniProtKB/Swiss-Prot: MYBB_HUMAN, P10244

Function: Transcription factor involved in the regulation of cell survival, proliferation, and

differentiation. Transactivates the expression of the CLU gene

Genatlas biochemistry entry for MYBL2:

avian myeloblastosis viral (v-myb) oncogene homolog-like 2

5 MGI mutant phenotypes (inferred from 6 alleles) (MGI details for Mybl2):

cellular

embryogenesis

lethality-prenatal/perinatal

no phenotypic analysis

normal

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	10770937

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for MYBL2

5/37 Interacting proteins for MYBL2 (P10244² ENSP00000217026³) via UniProtKB, MINT, and/or STRING (see all 37 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LIN9	Q5TKA1², ENSP00000355772³	MINT-4054250 MINT-4054241 MINT-4054263 MINT-4301520 STRING (score=.922)
E2F4	Q16254², ENSP00000368686³	MINT-4054181 STRING (score=.941)
HDAC2	Q92769², ENSP00000357621³	MINT-4054286 STRING (score=.716)
E2F3	O00716²	MINT-4053806
CDK2	ENSP00000266970³	STRING (score=.993)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MYBL2
4 Novoseek chemical compound relationships for MYBL2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
thymidine	22.45	3	1717494 (1), 9521863 (1), 11464857 (1)
dihydrofolate	20.78	1	12565705 (1)
oligonucleotide	0.00	1	11423988 (1)
tyrosine	0.00	1	17418011 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MYBL2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MYBL2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002466

Sigma-Aldrich siRNA for MYBL2

Sigma-Aldrich shRNA Panels and shRNA for MYBL2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002466

REFSEQ mRNAs for MYBL2 gene:

NM_002466.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002466

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002466
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002466
                                 untagged cDNA clone in CMV expression vector: NM_002466

Additional cDNA sequence:

AK223482.1 AK303249.1 AK314791.1 BC007585.1 BC053555.1 BX647151.1 CR591125.1 CR593650.1

CR598128.1 CR600287.1 CR620461.1 X13293.1

21 DOTS entries:

DT.100795111 DT.318246 DT.100038396 DT.99993278 DT.100795098 DT.91764270 DT.91764272 DT.100795097

DT.86590214 DT.95069875 DT.95170001 DT.120804957 DT.95169997 DT.95170000 DT.120804928 DT.120804954

DT.120804973 DT.120804978 DT.120804990 DT.91764255 DT.120804959

24/367 AceView cDNA sequences (see all 367 ):

BQ437722 BQ221748 BX353484 NM_002466 BG686935 BI858046 AW610505 BM830948

BE513316 CA455193 BM974810 BX482288 BU944590 BM823178 BQ071228 BE394157

BE279757 X13293 BM825590 BQ069161 R47814 BX388187 BM454013 BG117236

highest scoring ESTs for MYBL2:

X13293 AA102380 AA121314 AA150579 AA197300 AA206221 AA292433 AA308055 AA341315 AA393471

Unigene Cluster for MYBL2:

V-myb myeloblastosis viral oncogene homolog (avian)-like 2

Hs.179718 [show with all ESTs]

Unigene Representative Sequence: BX647151

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for MYBL2 (see all 13 )

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	·	9c	^	10	^	11	^	12a	·	12b	^	13a	·	13b	^	14	^	15a	·	15b	^	16a	·
SP1:							-		-						-				-		-																		-		-						-
SP2:							-		-						-				-
SP3:							-		-		-				-				-		-
SP4:																																															-				-
SP5:							-		-		-				-				-		-

ExUns:	16b	·	16c	^	17a	·	17b
SP1:			-
SP2:
SP3:
SP4:			-
SP5:

About this scheme

ECgene alternative splicing isoforms for MYBL2

2 Ensembl transcripts including schematic representations:

ENST00000396863 ENST00000217026

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MYBL2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MYBL2

¹ / ² / ³

3 probe-sets matching MYBL2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1854_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	X13293	1.00	0.90	0.95	1
201710_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002466	0.60	1.00	0.82	1
201710_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks MYBL2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGCTGCCCTG

SOURCE GeneReport for Unigene cluster: Hs.179718
Expression variation in blood from EXPOLDB for MYBL2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MYBL2 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MYBL2¹	--	v-myb myeloblastosis viral oncogene homolog (avian)-like more	88.49(n) 90.97(a)	477232 XM_534424.2 XP_534424.2
chimpanzee (Pan troglodytes)	MYBL2¹	--	v-myb myeloblastosis viral oncogene homolog (avian)-like more	98.57(n) 98.41(a)	458262 XM_514658.2 XP_514658.2
cow (Bos taurus)	MYBL2¹	--	v-myb myeloblastosis viral oncogene homolog (avian)-like more	87.39(n) 88.92(a)	510420 NM_001075448.1 NP_001068916.1
rat (Rattus norvegicus)	Mybl2¹	--	myeloblastosis oncogene-like 2	85(n) 88.54(a)	296344 XM_215922.4 XP_215922.4
mouse (Mus musculus)	Mybl2^{1, 5}	2 (93.00 cM)⁵	myeloblastosis oncogene-like 2^{1, 5}	84.24(n)¹ 85.82(a)¹	17865¹ NM_008652.2¹ NP_032678.1¹ AA624533⁵ AK028497⁵ (see all 13)

About this table Species with no ortholog for MYBL2

ENSEMBL Gene Tree for MYBL2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MYBL2 gene

MYB² MYBL1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/476 NCBI SNPs in MYBL2 are shown (see all 476 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 135)

AB	SNP ID	Valid	Chr 20 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2070235^1,2	A,C,F,H,O	41764871(+)	`AGAATA/GGCACC`	1	S/G	mis¹		19		MN EA EU WA NA CSAM	3008
	rs452734^1,2	A,C,F,H,O	41727294(-)	`AGGACA/GCTGAA`	1	--	ng5¹		7		MN EU EA WA NA	780
	rs285207^1,2	A,C,F,H	41728793(+)	`AGGGAA/CCCAGT`	1	--	ng5¹		6		EU EA WA MN	768
	rs619289^1,2	A,C,F,H	41728027(+)	`TGTGAC/TTGTGG`	1	--	ng5¹		25		NA EA NS EU WA MN CSAM	1954
	rs285175^1,2	C,F,H	41778877(+)	`GCCCAC/TTAACA`	1	--	ng3¹		12		EU EA WA NA MN CSAM	962
--	rs11556379^1,2	C,F,H	41777235(+)	`GGTATC/GAAAGA`	1	I/M	mis¹		12		EU EA WA	1228
	rs6017146^1,2	C,F,H	41764614(+)	`TATCAA/GCAACA`	1	N/S	mis¹		13		EU EA WA MN CSAM	1246
--	rs826943^1,2	A,C	41728107(+)	`cagcaC/Ttttgg`	1	--	ng5¹		0	--	--	--	--
--	rs826945^1,2	A,C	41728465(+)	`agatcA/Gcgcca`	1	--	ng5¹		0	--	--	--	--
	rs2664531^1,2	C,H	41764941(+)	`CCTGCC/GCTTCT`	1	P/R	mis¹		9		MN CSAM EA EU WA	824

About this table

HapMap Linkage Disequilibrium images for MYBL2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601415

8 Novoseek disease relationships for MYBL2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
retinoblastoma	52.12	9	11464857 (3), 9361185 (2), 8621601 (1), 11500496 (1) (see all 5)
tumors	10.63	18	10416595 (2), 16299810 (2), 19043454 (2), 17975021 (1) (see all 12)
cervical carcinoma	10.12	2	14506250 (1)
osteosarcoma	2.05	1	8621601 (1)
cancer lung	0.00	1	9865724 (1)
cancer	0.00	6	10228942 (3), 8812502 (1), 16914089 (1)
breast cancer	0.00	12	19043454 (4), 17418011 (3), 10815905 (1)
leukemia	0.00	1	11080802 (1)

About this table

Human Gene Mutation Database: MYBL2
Human Genome Epidemiology Navigator: MYBL2 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/162 PubMed articles for MYBL2 gene (see all 162 ):

Mybl2 (Bmyb) maps to mouse chromosome 2 and human chromosome 20q 13.1. (PubMed id 8812502)^{1, 2, 3} Noben-Trauth K....Klempnauer K.H. (1996)
The cell-cycle regulated transcription factor B-Myb is phosphorylated by cyclin A/Cdk2 at sites that enhance its transactivation properties. (PubMed id 9840932)^{1, 3, 4} Saville M.K. and Watson R.J. (1998)
Identification of cyclin A/Cdk2 phosphorylation sites in B-Myb. (PubMed id 10095772)^{1, 3, 4} Bartsch O.... Ferrari S. (1999)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{3, 4} Deloukas P....Rogers J. (2001)
Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB. (PubMed id 10770937)^{3, 4} Cervellera M.... Sala A. (2000)
Multiple nuclear localization signals of the B-myb gene product. (PubMed id 8062924)^{3, 4} Takemoto Y.... Ishii S. (1994)
Isolation of human cDNA clones of myb-related genes, A-myb and B- myb. (PubMed id 3060855)^{3, 4} Nomura N....Ishizaki R. (1988)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4605	HGNC: 7548	AceView: MYBL2	Ensembl:ENSG00000101057	euGenes: HUgn4605
ECgene: MYBL2	H-InvDB: MYBL2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MYBL2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MYBL2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MYBL2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MYBL2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MYBL2		Antibodies for MYBL2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MYBL2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MYBL2)
	Antibodies (MYBL2)
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MYBL2 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for MYBL2

Summaries
for MYBL2

Genomic Location
for MYBL2

Proteins
for MYBL2

Protein Domains/
Families
for MYBL2

Gene Function
for MYBL2

Pathways & Interactions
for MYBL2

Drugs & Compounds
for MYBL2

Transcripts
for MYBL2

Expression
for MYBL2

Orthologs
for MYBL2

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SNPs/Variants
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Disorders & Mutations
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for MYBL2

Search for MYBL2

Genome Databases showing MYBL2

Other Databases showing MYBL2

Specialized Databases showing MYBL2

Licensable Technologies
for MYBL2

Services
for MYBL2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MYBL2 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor MYBL2

Summariesfor MYBL2

Genomic Locationfor MYBL2

Proteinsfor MYBL2

Protein Domains/Familiesfor MYBL2

Gene Functionfor MYBL2

Pathways & Interactionsfor MYBL2

Drugs & Compoundsfor MYBL2

Transcriptsfor MYBL2

Expression for MYBL2

Orthologsfor MYBL2

Paralogsfor MYBL2

SNPs/Variantsfor MYBL2

Disorders & Mutationsfor MYBL2

Medical Newsfor MYBL2

Publicationsfor MYBL2

Search for MYBL2

Genome Databases showing MYBL2

Other Databases showing MYBL2

Specialized Databases showing MYBL2

Licensable Technologiesfor MYBL2

Servicesfor MYBL2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MYBL2

Summaries
for MYBL2

Genomic Location
for MYBL2

Proteins
for MYBL2

Protein Domains/
Families
for MYBL2

Gene Function
for MYBL2

Pathways & Interactions
for MYBL2

Drugs & Compounds
for MYBL2

Transcripts
for MYBL2

Expression
for MYBL2

Orthologs
for MYBL2

Paralogs
for MYBL2

SNPs/Variants
for MYBL2

Disorders & Mutations
for MYBL2

Medical News
for MYBL2

Publications
for MYBL2

Licensable Technologies
for MYBL2

Services
for MYBL2