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MYBBP1A Gene

protein-coding   GIFtS: 56
GCID: GC17M004442

MYB Binding Protein (P160) 1a

  See MYBBP1A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MYB Binding Protein (P160) 1a1 2
P1602 3 5
P53-Activated Protein-21 2
PAP22
Myb-Binding Protein 1A2

External Ids:    HGNC: 75461   Entrez Gene: 105142   Ensembl: ENSG000001323827   OMIM: 6048855   UniProtKB: Q9BQG03   

Export aliases for MYBBP1A gene to outside databases

Previous GC identifers: GC17M004867 GC17M004787 GC17M004393 GC17M004648 GC17M004388 GC17M004331


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MYBBP1A Gene:
This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind
specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular
processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate
splicing results in multiple transcript variants. (provided by RefSeq, Sep 2013)

GeneCards Summary for MYBBP1A Gene:
MYBBP1A (MYB binding protein (P160) 1a) is a protein-coding gene. Diseases associated with MYBBP1A include brain glioma, and mn1. GO annotations related to this gene include sequence-specific DNA binding and DNA-directed DNA polymerase activity.

UniProtKB/Swiss-Prot: MBB1A_HUMAN, Q9BQG0
Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins.
Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity)

Gene Wiki entry for MYBBP1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the MYBBP1A gene promoter:
         STAT5B   GR   AhR   Max1   ISGF-3   RFX1   AP-1   GR-beta   E47   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMYBBP1A promoter sequence
   Search Chromatin IP Primers for MYBBP1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MYBBP1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.3

MYBBP1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYBBP1A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M004442:  view genomic region     (about GC identifiers)

Start:
4,442,191 bp from pter      End:
4,458,926 bp from pter
Size:
16,736 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MBB1A_HUMAN, Q9BQG0 (See protein sequence)
Recommended Name: Myb-binding protein 1A  
Size: 1328 amino acids; 148855 Da
Subunit: Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds
to and represses PPARGC1A: this interaction is abrogated when PPARGC1A is phosphorylated by MAPK1/ERK. Binds to
and stimulates transcription by AHR. Binds to KPNA2. Component of the B-WICH complex, at least composed of
SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21 (By similarity)
Sequence caution: Sequence=CAB66530.1; Type=Erroneous initiation;
Secondary accessions: Q86VM3 Q9BW49 Q9P0V5 Q9UF99
Alternative splicing: 2 isoforms:  Q9BQG0-1   Q9BQG0-2   (May be due to competing donor and acceptor splice sites)

Explore the universe of human proteins at neXtProt for MYBBP1A: NX_Q9BQG0

Explore proteomics data for MYBBP1A at MOPED

Post-translational modifications: 

  • Citrullinated by PADI4 (By similarity)1
  • Ubiquitination2 at Lys56, Lys161, Lys179, Lys231, Lys988, Lys1036, Lys1140
  • Modification sites at PhosphoSitePlus

  • See MYBBP1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001099008.1  NP_055335.2  

    ENSEMBL proteins: 
     ENSP00000458919   ENSP00000254718   ENSP00000459692   ENSP00000460087   ENSP00000370968  

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    antibodies-online peptides for MYBBP1A

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR007015 DNA_pol_V
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9BQG0

    ProtoNet protein and cluster: Q9BQG0

    1 Blocks protein domain: IPB000515 Binding-protein-dependent transport systems inner membrane component


    Find genes that share domains with MYBBP1A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MBB1A_HUMAN, Q9BQG0
    Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins.
    Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity)

         Genatlas biochemistry entry for MYBBP1A:
    MYB binding protein 1A,expressed in pancreas,kidney,brain,colon,prostate,nuclear predominantly localized in the
    nucleolus

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003887DNA-directed DNA polymerase activity IEA--
    GO:0005488binding ----
    GO:0005515protein binding IPI17255935
    GO:0008134transcription factor binding TAS10644447
         
    Find genes that share ontologies with MYBBP1A           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Mybbp1a):
     embryogenesis  mortality/aging 

    Find genes that share phenotypes with MYBBP1A           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MYBBP1A

    miRNA
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    miRTarBase miRNAs that target MYBBP1A:
    hsa-mir-193b-3p (MIRT041453), hsa-mir-30b-3p (MIRT038652), hsa-mir-26b-5p (MIRT029101), hsa-mir-331-3p (MIRT043518), hsa-mir-183-5p (MIRT047122), hsa-mir-98-5p (MIRT027438), hsa-mir-92a-3p (MIRT049640)

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    hsa-miR-877* hsa-miR-1236 hsa-miR-551b* hsa-miR-744* hsa-miR-3667-3p
    SwitchGear 3'UTR luciferase reporter plasmidMYBBP1A 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MBB1A_HUMAN, Q9BQG0: Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and cytoplasm.
    Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity).
    Predominantly nucleolar
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005730nucleolus ISS--
    GO:0005737cytoplasm ISS--
    GO:0042564NLS-dependent protein nuclear import complex ISS--
    GO:0043231intracellular membrane-bounded organelle IDA--

    Find genes that share ontologies with MYBBP1A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MYBBP1A About    
    See pathways by source

    SuperPathContained pathways About
    1Energy Metabolism
    Energy Metabolism


    1 BioSystems Pathway for MYBBP1A
        Energy Metabolism


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MYBBP1A
    Interactions:

        GeneGlobe Interaction Network for MYBBP1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MYBBP1A (Q9BQG01, 2, 3 ENSP000003709684) via UniProtKB, MINT, STRING, and/or I2D (see all 746)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DHX30Q7L2E31, 2, 3, ENSP000003926014EBI-676973,EBI-1211456 MINT-4303274 MINT-4303326 MINT-4303144 MINT-6488791 I2D: score=3 STRING: ENSP00000392601
    NR2E3Q9Y5X41, 2, 3EBI-676973,EBI-7216962 MINT-4303589 MINT-4303550 I2D: score=3 
    SMN1Q166372, 3, ENSP000003700834MINT-7947479 I2D: score=3 STRING: ENSP00000370083
    SMN2Q166372, 3, ENSP000003701194MINT-7947479 I2D: score=3 STRING: ENSP00000370119
    NCLP193382, 3, ENSP000003181954MINT-6488791 I2D: score=1 STRING: ENSP00000318195
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated TAS10644447
    GO:0006913nucleocytoplasmic transport ISS--
    GO:0022904respiratory electron transport chain IEA--
    GO:0042149cellular response to glucose starvation IDA--

    Find genes that share ontologies with MYBBP1A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for MYBBP1A (MBB1A)

    6 HMDB Compounds for MYBBP1A    About this table
    CompoundSynonyms CAS #PubMed Ids
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--
    Thymidine 5'-triphosphate2'-Deoxythymidine 5'-triphosphate (see all 13)365-08-2--
    dATP2'-Deoxy-5'-ATP (see all 8)1927-31-7--
    dCTP2'-deoxycytidine-5'-triphosphate (see all 4)2056-98-6--
    dGTP2'-Deoxyguanosine 5'-triphosphate (see all 4)2564-35-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MYBBP1A gene (2 alternative transcripts): 
    NM_001105538.1  NM_014520.3  

    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000571368 ENST00000573116 ENST00000254718(uc010vsa.2 uc002fyb.4)
    ENST00000574934(uc002fya.4) ENST00000573723 ENST00000574547 ENST00000574167
    ENST00000572759 ENST00000575662 ENST00000571354 ENST00000573175 ENST00000570986
    ENST00000381556(uc002fxz.4)
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    Selected AceView cDNA sequences (see all 158):

    AL136595 AI568506 BQ230254 BM469107 BC000641 BQ896327 BG391735 BM809215 
    CA488708 T06955 AA356844 CF142562 AW502496 AA325004 BC050546 AL701346 
    AW407071 BQ129207 BM799587 CB215833 BP349200 BM810940 AL133098 AI569350 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MYBBP1A (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b ^ 20a · 20b ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21a · 21b ^ 22 ^ 23a · 23b · 23c · 23d ^ 24a · 24b ^ 25 ^ 26 ^ 27a · 27b · 27c
    SP1:                                                                                    
    SP2:                    -     -                                                         
    SP3:                    -     -                                                         
    SP4:                    -     -                                                         
    SP5:                    -     -                                                         


    ECgene alternative splicing isoforms for MYBBP1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MYBBP1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCAGGGCTC
    MYBBP1A Expression
    About this image


    MYBBP1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Mesencephalic Ventricular Zone
     
     Thymus (Hematopoietic System)
             Thymus
     
     Gut Tube (Gastrointestinal Tract)
             Midgut
     
     Bone (Muscoskeletal System)
             Bone Marrow
    MYBBP1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MYBBP1A Protein Expression
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

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    This gene was present in the common ancestor of chordates.

    Orthologs for MYBBP1A gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mybbp1a1 , 5 MYB binding protein (P160) 1a1, 5 76.27(n)1
    70.72(a)1
      11 (44.29 cM)5
    184321  NM_016776.21  NP_058056.21 
     724413555 
    chicken
    (Gallus gallus)
    Aves MYBBP1A1 MYB binding protein (P160) 1a 60.08(n)
    53.97(a)
      417491  XM_415739.4  XP_415739.4 
    lizard
    (Anolis carolinensis)
    Reptilia MYBBP1A6
    MYB binding protein (P160) 1a
    47(a)
    1 ↔ 1
    GL344337.1(2702-41609)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.188012 Transcribed sequence with weak similarity to protein more 72.61(n)    AL898712.2 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.252512 Danio rerio cDNA clone IMAGE3815533, partial cds 70.43(n)    BC058070.1 


    ENSEMBL Gene Tree for MYBBP1A (if available)
    TreeFam Gene Tree for MYBBP1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MYBBP1A (see all 772)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs603603561,2
    C--4439373(+) AAAAA-/A/A   
       AAAAA
    GAACC
    2 -- int11NA 2
    rs1464070721,2
    F--4443750(+) ACACCC/GAGGAG 4 L syn11Minor allele frequency- G:0.00NA 4480
    rs748224991,2
    C,F--4443756(+) AGGAGC/TACCGT 4 V syn12Minor allele frequency- T:0.00EA NA 4602
    rs1429891221,2
    C,F--4443760(+) GCACCG/ATCAGG 4 /T /M mis12Minor allele frequency- A:0.00NA EU 5363
    rs2017532331,2
    C--4443788(+) CAGAGA/GGTGGG 2 -- int10--------
    rs1390468651,2
    --4443832(+) CTCTCA/GCGGGC 2 -- int10--------
    rs1861281821,2
    --4443860(+) CTGCCC/GTGTTG 2 -- int10--------
    rs1905014531,2
    --4443932(+) CATCCA/GTGTCT 2 -- int10--------
    rs1476741441,2
    C--4443976(+) TGGTT-/CTCCTCCT 2 -- int10--------
    rs352875231,2
    C--4443978(+) CTCCT-/CCTTCCCA 2 -- int10--------

    HapMap Linkage Disequilibrium report for MYBBP1A (4442191 - 4458926 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for MYBBP1A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2715555CNV Deletion23290073
    nsv907605CNV Loss21882294
    dgv3051n71CNV Loss21882294
    dgv3050n71CNV Loss21882294
    dgv3049n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): MYBBP1A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MYBBP1A
    DNA2.0 Custom Variant and Variant Library Synthesis for MYBBP1A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604885    OMIM disorders: --

    2 diseases for MYBBP1A:    
    About MalaCards
    brain glioma    mn1


    Find genes that share disorders with MYBBP1A           About GenesLikeMe

    Genetic Association Database (GAD): MYBBP1A
    Human Genome Epidemiology (HuGE) Navigator: MYBBP1A (1 document)

    Export disorders for MYBBP1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MYBBP1A gene, integrated from 10 sources (see all 100):
    (articles sorted by number of sources associating them with MYBBP1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3. (PubMed id 10644447)1, 2, 3, 9 Keough R.... Gonda T.J. (Genomics 1999)
    2. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1, 4 Lu Y....Boer J.M. (J. Lipid Res. 2008)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription. (PubMed id 16603771)1, 2 Cavellan E.... Oestlund Farrants A.-K. (J. Biol. Chem. 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    8. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    9. Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase. (PubMed id 20177074)1, 9 Perrera C....Rusconi L. (J. Biol. Chem. 2010)
    10. MYBBP1a is a novel repressor of NF-kappaB. (PubMed id 17196614)1, 9 Owen H.R....Hottiger M.O. (J. Mol. Biol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10514 HGNC: 7546 AceView: MYBBP1A Ensembl:ENSG00000132382 euGenes: HUgn10514
    ECgene: MYBBP1A H-InvDB: MYBBP1A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MYBBP1A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MYBBP1A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MYBBP1A gene:
    Search GeneIP for patents involving MYBBP1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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